Epstein-Barr virus infection and nasopharyngeal carcinoma

scientific article published on October 2017

Epstein-Barr virus infection and nasopharyngeal carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1098/RSTB.2016.0270
P932PMC publication ID5597737
P698PubMed publication ID28893937

P50authorKwok Wai LoQ59247702
Chi Man TsangQ90584750
P2093author name stringSai Wah Tsao
P2860cites workAn Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survivalQ24649032
From Conventional to Next Generation Sequencing of Epstein-Barr Virus GenomesQ26765442
Understanding the interplay between host immunity and Epstein-Barr virus in NPC patientsQ26823898
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Epstein-Barr virus latent genesQ28082701
Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinomaQ28191706
Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodiesQ39666008
Epstein-Barr virus BRLF1 inhibits transcription of IRF3 and IRF7 and suppresses induction of interferon-betaQ39716669
A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.Q39736828
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signalingQ28588278
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility lociQ28943422
Deciphering the molecular genetic basis of NPC through molecular, cytogenetic, and epigenetic approachesQ29036707
Epstein-Barr virus: 40 years onQ29617969
TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinomaQ30491128
Epstein-Barr virus particles induce centrosome amplification and chromosomal instabilityQ30838642
Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinomaQ33254109
Laser-capture microdissection of oropharyngeal epithelium indicates restriction of Epstein-Barr virus receptor/CD21 mRNA to tonsil epithelial cellsQ33360874
Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodiesQ33373662
Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinomaQ33598586
Epstein-Barr virus BARF1 protein is dispensable for B-cell transformation and inhibits alpha interferon secretion from mononuclear cells.Q33650107
Epstein-Barr Virus Interferes with the Amplification of IFNα Secretion by Activating Suppressor of Cytokine Signaling 3 in Primary Human MonocytesQ33650938
Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cellsQ33760239
The Epstein-Barr virus BARF1 gene encodes a novel, soluble colony-stimulating factor-1 receptor.Q33782739
Differences in B cell growth phenotype reflect novel patterns of Epstein-Barr virus latent gene expression in Burkitt's lymphoma cellsQ33929593
VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMAQ33971399
Epstein-Barr virus latent membrane protein-2A-induced DeltaNp63alpha expression is associated with impaired epithelial-cell differentiationQ34029669
The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferasesQ34099074
Histology of the human nasopharyngeal mucosaQ34105490
Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.Q34200710
Oral dysplasia and squamous cell carcinoma: correlation between increased expression of CD21, Epstein-Barr virus and CK19.Q34237606
Genome-wide DNA methylation as an epigenetic consequence of Epstein-Barr virus infection of immortalized keratinocytesQ34261921
Loss of the tumor suppressor PML in human cancers of multiple histologic originsQ34299352
Epstein-Barr virus BALF3 mediates genomic instability and progressive malignancy in nasopharyngeal carcinomaQ34483687
High resolution allelotype of microdissected primary nasopharyngeal carcinoma.Q34509844
High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinomaQ34515210
CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.Q34533871
Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutationsQ34549536
Resting B cells as a transfer vehicle for Epstein-Barr virus infection of epithelial cellsQ34598541
Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cellsQ34712473
The Epstein-Barr virus encoded BART miRNAs potentiate tumor growth in vivoQ34973323
The significance of LMP1 expression in nasopharyngeal carcinomaQ35008886
Oncogenic induction of cellular high CpG methylation by Epstein-Barr virus in malignant epithelial cellsQ35020438
Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cellsQ35119824
NF-kappaB inhibits gammaherpesvirus lytic replicationQ35155154
Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization.Q39749474
Expression of Epstein-Barr nuclear antigen 1 in gastric carcinoma cells is associated with enhanced tumorigenicity and reduced cisplatin sensitivityQ39767918
The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation.Q39806231
Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinomaQ39865449
Attempts to detect virus-specific DNA sequences in human tumors. III. Epstein-Barr viral DNA in non-lymphoid nasopharyngeal carcinoma cellsQ39929408
Epstein-Barr virus B95.8 produced in 293 cells shows marked tropism for differentiated primary epithelial cells and reveals interindividual variation in susceptibility to viral infectionQ40148095
Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signalingQ40192981
Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinomaQ40372899
Epstein-Barr virus-encoded poly(A)- RNA confers resistance to apoptosis mediated through Fas by blocking the PKR pathway in human epithelial intestine 407 cells.Q40373897
Epstein-Barr virus latent membrane protein 1 represses p53-mediated DNA repair and transcriptional activity.Q40435357
Phenotypic alterations induced by the Hong Kong-prevalent Epstein-Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cellsQ40577418
Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1.Q40641449
Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virusQ40934947
EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loopQ41122951
Enhanced malignant progression of nasopharyngeal carcinoma cells mediated by the expression of Epstein-Barr nuclear antigen 1 in vivoQ41153139
Hypermethylation of the p16 gene in nasopharyngeal carcinomaQ41191384
Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1.Q41549956
Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers.Q41868979
Regulation of APC/CCdc20 activity by RASSF1A-APC/CCdc20 circuitryQ41980393
Sequence-based typing of HLA-A gene in 930 patients with nasopharyngeal carcinoma in Hunan province, southern ChinaQ42144225
Etiological factors of nasopharyngeal carcinomaQ42231417
Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomasQ42262852
Identification of a human epithelial cell surface protein sharing an epitope with the C3d/Epstein-Barr virus receptor molecule of B lymphocytesQ42490090
The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferationQ43610021
Promoter hypermethylation of multiple genes in nasopharyngeal carcinomaQ43860639
Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern ChineseQ44192526
PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survivalQ45226982
Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomasQ45424270
Nasopharyngeal intraepithelial lesion: latent Epstein-Barr virus infection with malignant potentialQ45608351
Inhibition of IFN-gamma signaling by an Epstein-Barr virus immediate-early proteinQ45734610
Coinfection of multiple strains of Epstein-Barr virus in immunocompetent normal individuals: reassessment of the viral carrier stateQ45743571
Specific latent membrane protein 1 gene sequences in type 1 and type 2 Epstein-Barr virus from nasopharyngeal carcinoma in Hong Kong.Q45756231
Epstein-Barr virus in Burkitt's lymphoma and nasopharyngeal carcinoma. Antibodies to EBV associated membrane and viral capsid antigens in Burkitt lymphoma patientsQ45822159
Epidemiology of nasopharyngeal carcinoma.Q45948135
Recurrent chemical reactivations of EBV promotes genome instability and enhances tumor progression of nasopharyngeal carcinoma cells.Q46170131
Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cellsQ47978435
PIK3CA mutations in nasopharyngeal carcinoma.Q53355100
Epstein-Barr virus and nasopharyngeal carcinomaQ56947843
p16 gene alterations in nasopharyngeal carcinomaQ72220049
High frequency of chromosome 3p deletion in histologically normal nasopharyngeal epithelia from southern ChineseQ73083791
Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasisQ77340409
Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisationQ77995454
Identification of a novel 12p13.3 amplicon in nasopharyngeal carcinomaQ84493563
Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinomaQ38480025
Epstein-Barr Virus Strain VariationQ38596335
Nasopharyngeal Carcinoma: An Evolving Role for the Epstein-Barr VirusQ38596356
EBNA1.Q38597231
The Latent Membrane Protein 1 (LMP1).Q38597238
Epstein-Barr Virus Lytic Cycle ReactivationQ38597247
Immune Evasion by Epstein-Barr VirusQ38597254
Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3.Q38610363
Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cellsQ38928572
Epstein-Barr virus: more than 50 years old and still providing surprises.Q38968588
The genomic landscape of nasopharyngeal carcinomaQ38982367
Epstein-Barr virus induction of the Hedgehog signalling pathway imposes a stem cell phenotype on human epithelial cellsQ39112082
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.Q39123741
Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK activationQ39148562
Epstein-Barr virus-encoded miR-BART20-5p inhibits T-bet translation with secondary suppression of p53 in invasive nasal NK/T-cell lymphomaQ39162375
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β productionQ39277512
Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinomaQ39455578
Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV-associated nasopharyngeal carcinoma.Q39456193
The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stressQ39577788
Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cellsQ39578660
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection.Q39614564
Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphomaQ39646759
Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell linesQ35363169
Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatinQ35505126
EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell SurvivalQ35662292
Focus on nasopharyngeal carcinomaQ35773862
Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factorsQ35812949
The role of miRNAs and EBV BARTs in NPC.Q35924359
The Epstein-Barr Virus BART microRNAs target the pro-apoptotic protein Bim.Q35924384
Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma.Q35928927
Nonmuscle myosin heavy chain IIA mediates Epstein-Barr virus infection of nasopharyngeal epithelial cellsQ36055637
Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse modelQ36099024
An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse modelQ36171933
Recurrent FGFR3-TACC3 fusion gene in nasopharyngeal carcinomaQ36211300
EBV-encoded RNA via TLR3 induces inflammation in nasopharyngeal carcinomaQ36414449
The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition grooveQ36433849
A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese AncestryQ36463672
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cellsQ36483613
Epstein-Barr virus-induced epigenetic alterations following transient infectionQ36625981
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cellsQ36734903
Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cellsQ36845616
NF-κB Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma.Q37073277
The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species.Q37114836
New insights into the role of PML in tumour suppressionQ37173760
Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.Q37301260
ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA DemethylationQ37314790
Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.Q37323204
Human leukocyte antigens and epstein-barr virus-associated nasopharyngeal carcinoma: old associations offer new clues into the role of immunity in infection-associated cancers.Q37376994
Role of EBER and BARF1 in nasopharyngeal carcinoma (NPC) tumorigenesisQ37972526
Host-tumor interactions in nasopharyngeal carcinomasQ37976234
The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).Q37976235
Familial and large-scale case-control studies identify genes associated with nasopharyngeal carcinomaQ37982181
Epstein-Barr virus infection as an epigenetic driver of tumorigenesisQ38023841
The role of Epstein-Barr virus in epithelial malignanciesQ38253914
Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinomaQ38273731
Qualitative analysis of the expression of Epstein-Barr virus lytic genes in nasopharyngeal carcinoma biopsiesQ38294587
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.Q38307191
P433issue1732
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
P577publication date2017-10-01
P1433published inPhilosophical Transactions of the Royal Society BQ2153239
P1476titleEpstein-Barr virus infection and nasopharyngeal carcinoma
P478volume372

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