Interplay of Viral Infection, Host Cell Factors and Tumor Microenvironment in the Pathogenesis of Nasopharyngeal Carcinoma.

scientific article published on 4 April 2018

Interplay of Viral Infection, Host Cell Factors and Tumor Microenvironment in the Pathogenesis of Nasopharyngeal Carcinoma. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/CANCERS10040106
P932PMC publication ID5923361
P698PubMed publication ID29617291

P2093author name stringSai Wah Tsao
Chi Man Tsang
Shaina Chor Mei Huang
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Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinomaQ47248660
EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinomaQ47259217
Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9Q33265945
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Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinomaQ33598586
Characterization of Epstein-Barr Virus miRNAome in Nasopharyngeal Carcinoma by Deep SequencingQ33700293
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VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMAQ33971399
MicroRNA miR-BART20-5p stabilizes Epstein-Barr virus latency by directly targeting BZLF1 and BRLF1Q34059350
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomesQ34171808
Targeting Epstein-Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapyQ34171822
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasisQ34228703
Epstein-Barr virus-encoded latent membrane protein 2A promotes the epithelial-mesenchymal transition in nasopharyngeal carcinoma via metastatic tumor antigen 1 and mechanistic target of rapamycin signaling inductionQ34261571
Expression of cytokine and chemokine genes in Epstein-Barr virus-associated nasopharyngeal carcinoma: comparison with Hodgkin's diseaseQ34278487
Extra-cellular release and blood diffusion of BART viral micro-RNAs produced by EBV-infected nasopharyngeal carcinoma cells.Q34282719
Ectopic expression of DICE1 suppresses tumor cell growth.Q34333513
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Human tumor virus utilizes exosomes for intercellular communication.Q34377767
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Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutationsQ34549536
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LMP1 strain variants: biological and molecular properties.Q34717145
Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinomaQ34745799
The biological role of the Fas/FasL system during tumor formation and progressionQ34766094
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The Epstein-Barr virus encoded BART miRNAs potentiate tumor growth in vivoQ34973323
Epstein-Barr virus in the pathogenesis of NPC.Q35008870
The significance of LMP1 expression in nasopharyngeal carcinomaQ35008886
EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapyQ35067875
Epstein-Barr virus Zta-induced immunomodulators from nasopharyngeal carcinoma cells upregulate interleukin-10 production from monocytesQ35077651
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signallingQ35194008
Distribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma.Q35570420
EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell SurvivalQ35662292
Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigrationQ35755712
Gold nano-particles (AuNPs) carrying anti-EBV-miR-BART7-3p inhibit growth of EBV-positive nasopharyngeal carcinomaQ35781438
Epstein-Barr virus: more than 50 years old and still providing surprises.Q38968588
Down-regulation of miRNA-204 by LMP-1 enhances CDC42 activity and facilitates invasion of EBV-associated nasopharyngeal carcinoma cellsQ39016871
NF-κB-mediated transcriptional upregulation of TNFAIP2 by the Epstein-Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma.Q39105321
Overexpression of Epstein-Barr virus-encoded microRNA-BART7 in undifferentiated nasopharyngeal carcinomaQ39306381
Epstein-Barr viral microRNAs target caspase 3.Q39449661
Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cellsQ39578660
MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells.Q39664249
Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokinesQ39679329
Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibitionQ39682274
The EBV-encoded latent membrane proteins, LMP2A and LMP2B, limit the actions of interferon by targeting interferon receptors for degradation.Q39806231
Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma.Q39903979
Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitroQ39927855
Efficiency of transformation of lymphocytes by Epstein-Barr virusQ40044594
Epstein-Barr virus infection and nasopharyngeal carcinomaQ40046633
Epithelial-mesenchymal transitions: twist in development and metastasisQ35856121
Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinomaQ35865016
The Epstein-Barr Virus BART microRNAs target the pro-apoptotic protein Bim.Q35924384
Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9Q36086653
Modulation of LMP1 protein expression by EBV-encoded microRNAsQ36092565
Epstein-Barr virus: an important vaccine target for cancer preventionQ36408680
EBV-encoded RNA via TLR3 induces inflammation in nasopharyngeal carcinomaQ36414449
Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasisQ36467398
Epstein-Barr virus (EBV) and its associated human cancers--genetics, epigenetics, pathobiology and novel therapeutics.Q36486650
Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cellsQ36498181
EBV-miR-BART10-3p facilitates epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRCQ36561585
Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma.Q36697762
Alterations of the p53 gene in nasopharyngeal carcinomaQ36698270
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cellsQ36734903
Expression of the Epstein-Barr virus immediate early gene, BZLF1, in nasopharyngeal carcinoma tumor cellsQ36753036
Potential selection of LMP1 variants in nasopharyngeal carcinomaQ36944141
Clinical and biological significance of HAX-1 overexpression in nasopharyngeal carcinomaQ37022210
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implicationsQ37160617
E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancerQ37372547
Clonal transformation of adult human leukocytes by Epstein-Barr virusQ37506764
Role of EBNA1 in NPC tumourigenesisQ37972201
Host-tumor interactions in nasopharyngeal carcinomasQ37976234
The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).Q37976235
Switching of EBV cycles between latent and lytic statesQ38171455
The role of Epstein-Barr virus in epithelial malignanciesQ38253914
The role of Epstein-Barr virus infection in the pathogenesis of nasopharyngeal carcinomaQ38440804
Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinomaQ38480025
Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3.Q38714699
Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling PathwaysQ38722933
Epstein-Barr virus LMP1 induces focal adhesions and epithelial cell migration through effects on integrin-α5 and N-cadherinQ38826798
Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins.Q38889253
Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cellsQ38928572
Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cellsQ38943928
EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN.Q38944897
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P577publication date2018-04-04
P1433published inCancersQ27722963
P1476titleInterplay of Viral Infection, Host Cell Factors and Tumor Microenvironment in the Pathogenesis of Nasopharyngeal Carcinoma.
P478volume10

Reverse relations

cites work (P2860)
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