Nasopharyngeal Carcinoma: An Evolving Role for the Epstein-Barr Virus

scientific article published on January 2015

Nasopharyngeal Carcinoma: An Evolving Role for the Epstein-Barr Virus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/978-3-319-22822-8_14
P698PubMed publication ID26424653

P50authorNancy Raab-TraubQ90483481
P2860cites workImmunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasmsQ70456616
Localization of the Epstein-Barr virus protein LMP 1 to exosomesQ45237056
Differential signaling pathways are activated in the Epstein-Barr virus-associated malignancies nasopharyngeal carcinoma and Hodgkin lymphomaQ45605928
Molecular markers of clonality and identity in Epstein-Barr virus-associated B-cell lymphoproliferative diseaseQ45613226
Comparison of plasma Epstein-Barr virus (EBV) DNA levels and serum EBV immunoglobulin A/virus capsid antigen antibody titers in patients with nasopharyngeal carcinomaQ45665252
Epstein-Barr virus latent membrane protein 2A has no growth-altering effects when expressed in differentiating epitheliaQ45740958
Antibodies to the Epstein-Barr virus transactivator protein (ZEBRA) as a valuable biomarker in young patients with nasopharyngeal carcinomaQ45743631
The A20 protein interacts with the Epstein-Barr virus latent membrane protein 1 (LMP1) and alters the LMP1/TRAF1/TRADD complexQ45746529
Sequence variation in the Epstein-Barr virus latent membrane protein 1.Q45782895
Epstein–Barr Virus Replication in Oropharyngeal Epithelial CellsQ45796774
DNA of Epstein-Barr virus VIII: B95-8, the previous prototype, is an unusual deletion derivativeQ45803144
Separation of Epstein-Barr virus DNA from large chromosomal DNA in non-virus-producing cells.Q45820444
Demonstration of Epstein-Barr virus-associated nuclear antigen in nasopharyngeal carcinoma cells from fresh biopsiesQ45826327
Prospective studies on nasopharyngeal carcinoma in Epstein-Barr virus IgA/VCA antibody-positive persons in Wuzhou City, ChinaQ45827831
Detection of Antigens Associated With Epstein-Barr Virus Replication in Extracts From Biopsy Specimens of Nasopharyngeal CarcinomasQ45831879
The differentiated form of nasopharyngeal carcinoma contains Epstein-Barr virus DNA.Q45835618
Latent and replicating forms of Epstein-Barr virus DNA in lymphomas and lymphoproliferative diseasesQ45845223
Detection and prevalence of the “f” variant of epstein-barr virus in Southern ChinaQ45862289
EBV specific CTL: a model for immune therapyQ45888825
Clonal antigen receptor gene rearrangements and Epstein-Barr viral DNA in tissues of Hodgkin's diseaseQ46254634
EBV persistence in memory B cells in vivo.Q52037383
An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.Q53541156
Salted fish and nasopharyngeal carcinoma in southern ChineseQ66698677
Cytogenetics of undifferentiated nasopharyngeal carcinoma xenografts from southern ChineseQ69599721
Establishment and characterization of three transplantable EBV-containing nasopharyngeal carcinomasQ70061763
Structure and coding content of CST (BART) family RNAs of Epstein-Barr virusQ24524755
An Epstein-Barr virus protein interacts with NotchQ24529019
Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosisQ24632165
The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaBQ24646694
An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survivalQ24649032
Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressedQ25257225
A novel persistence associated EBV miRNA expression profile is disrupted in neoplasiaQ27349177
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalizationQ28243346
Identification of virus-encoded microRNAsQ28259309
The enigmatic epidemiology of nasopharyngeal carcinomaQ28268076
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9Q33265945
Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodiesQ33373662
EBV gene expression in an NPC-related tumour.Q33576708
Augmented latent membrane protein 1 expression from Epstein-Barr virus episomes with minimal terminal repeatsQ33649035
Characterization of Epstein-Barr Virus miRNAome in Nasopharyngeal Carcinoma by Deep SequencingQ33700293
Epstein-Barr virus provides a survival factor to Burkitt's lymphomasQ33716529
Transfer of EBV-specific CTL to prevent EBV lymphoma post bone marrow transplantQ33762569
Interaction of tumor necrosis factor receptor-associated factor signaling proteins with the latent membrane protein 1 PXQXT motif is essential for induction of epidermal growth factor receptor expressionQ33786551
Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathwayQ33787396
Epstein-Barr virus in Burkitt's lymphoma: a role for latent membrane protein 2AQ33794029
A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirusQ33838266
Epstein-Barr virus small nuclear RNAs are not expressed in permissively infected cells in AIDS-associated leukoplakiaQ33891606
miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesisQ34023389
Epstein-Barr virus latent membrane protein-2A-induced DeltaNp63alpha expression is associated with impaired epithelial-cell differentiationQ34029669
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomesQ34171808
Human tumor virus utilizes exosomes for intercellular communication.Q34377767
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomasQ34457976
Quantitative Studies of Epstein-Barr Virus-Encoded MicroRNAs Provide Novel Insights into Their RegulationQ34485302
Epstein-barr virus-specific IgA serum antibodies as an outstanding feature of nasopharyngeal carcinomaQ34579494
Efficient replication of Epstein-Barr virus in stratified epithelium in vitroQ34581330
Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitroQ34717880
The Epstein-Barr virus encoded BART miRNAs potentiate tumor growth in vivoQ34973323
Itchy, a Nedd4 Ubiquitin Ligase, Downregulates Latent Membrane Protein 2A Activity in B-Cell SignalingQ34975783
Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genesQ35080523
Length of Epstein-Barr virus termini as a determinant of epithelial cell clonal emergenceQ35155351
The role of miRNAs and EBV BARTs in NPC.Q35924359
The Epstein-Barr Virus BART microRNAs target the pro-apoptotic protein Bim.Q35924384
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.Q35943724
Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt PathwayQ35948025
Infection of Epstein-Barr virus in a gastric carcinoma cell line induces anchorage independence and global changes in gene expressionQ36066487
Unique signaling properties of CTAR1 in LMP1-mediated transformationQ36098869
Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignanciesQ36231550
Modelling glandular epithelial cancers in three-dimensional culturesQ36251934
A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cellsQ36263086
Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk- and Akt-dependent epithelial migration through αv-integrin membrane translocationQ36276627
Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent mannerQ36324519
Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic miceQ36327458
Epstein-Barr virus (B95-8) DNA VII: molecular cloning and detailed mappingQ36390998
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cellsQ36483613
Epstein-Barr virus LMP1 modulates lipid raft microdomains and the vimentin cytoskeleton for signal transduction and transformationQ36559750
Cellular responses to viral infection in humans: lessons from Epstein-Barr virus.Q36766875
Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.Q36890676
Potential selection of LMP1 variants in nasopharyngeal carcinomaQ36944141
IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3Q36984994
Modulation of B-cell exosome proteins by gamma herpesvirus infectionQ37068487
Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cellsQ37093324
Epstein-Barr virus latent membrane protein 2 effects on epithelial acinus development reveal distinct requirements for the PY and YEEA motifsQ37336691
Proof for EBV's sustaining role in Burkitt's lymphomasQ37463625
Expression profile of microRNAs in Epstein-Barr virus-infected AGS gastric carcinoma cellsQ37547400
Restricted Epstein-Barr virus protein expression in Burkitt lymphoma is due to a different Epstein-Barr nuclear antigen 1 transcriptional initiation siteQ37552683
Qualitative analysis of the expression of Epstein-Barr virus lytic genes in nasopharyngeal carcinoma biopsiesQ38294587
Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinomaQ38480025
Molecular cytogenetic characterization of nasopharyngeal carcinoma cell lines and xenografts by comparative genomic hybridization and spectral karyotypingQ38484975
Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3.Q38610363
Epstein-Barr virus nuclear antigen 1 replication and segregation functions in nasopharyngeal carcinoma cell linesQ38748334
Diet, living conditions and nasopharyngeal carcinoma in Tunisia--a case-control studyQ39102898
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.Q39123741
Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinomaQ39455578
Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt.Q39585482
Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdeltaQ39595269
Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodiesQ39666008
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assayQ39711736
Overexpression of delta Np63 in a human nasopharyngeal carcinoma cell line downregulates CKIs and enhances cell proliferationQ39904201
Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinomaQ39952661
EBV latent membrane proteins (LMPs) 1 and 2 as immunotherapeutic targets: LMP-specific CD4+ cytotoxic T cell recognition of EBV-transformed B cell lines.Q40022307
Replication of EBV in epithelial cells during infectious mononucleosisQ40086221
Roles of lytic viral infection and IL-6 in early versus late passage lymphoblastoid cell lines and EBV-associated lymphoproliferative diseaseQ40129013
Identification of Epstein-Barr virus RK-BARF0-interacting proteins and characterization of expression pattern.Q40275967
Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cellsQ40326039
Epstein-Barr virus latent membrane protein 1 CTAR1 mediates rodent and human fibroblast transformation through activation of PI3K.Q40399583
Induction of Id1 and Id3 by latent membrane protein 1 of Epstein-Barr virus and regulation of p27/Kip and cyclin-dependent kinase 2 in rodent fibroblast transformationQ40487971
TRAF interactions with raft-like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1.Q40512215
RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinomaQ40577439
Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathwayQ40623366
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodelingQ40687983
EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasivenessQ40718647
Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virusQ40934947
Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strainsQ40936386
Relative levels of EBNA1 gene transcripts from the C/W, F and Q promoters in Epstein-Barr virus-transformed lymphoid cells in latent and lytic stages of infectionQ40967827
Regulation of Epstein-Barr virus latency by latent membrane protein 2.Q41125684
Detection of Epstein-Barr Virus DNA in well and poorly differentiated nasopharyngeal carcinoma cell linesQ41244707
The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferationQ43610021
Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative diseaseQ43936463
Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinomaQ43947306
The terminal protein gene 2 of Epstein-Barr virus is transcribed from a bidirectional latent promoter regionQ44081032
Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern ChineseQ44192526
Profiling of Epstein-Barr virus-encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs.Q44833814
P433issuePt 1
P921main subjectEpstein–Barr virusQ6900
P304page(s)339-363
P577publication date2015-01-01
P1433published inCurrent Topics in Microbiology and ImmunologyQ15752446
P1476titleNasopharyngeal Carcinoma: An Evolving Role for the Epstein-Barr Virus
P478volume390

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