New Insights from Elucidating the Role of LMP1 in Nasopharyngeal Carcinoma.

scientific article published on 21 March 2018

New Insights from Elucidating the Role of LMP1 in Nasopharyngeal Carcinoma. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/CANCERS10040086
P932PMC publication ID5923341
P698PubMed publication ID29561768

P50authorVaughn S. CooperQ41050411
P2093author name stringKathy H Y Shair
Akhil Reddy
P2860cites workAssociation of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in TaiwanQ78608443
LMP1 signaling and activation of NF-kappaB in LMP1 transgenic miceQ81398990
Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cellsQ24294987
Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinomaQ24298635
Compartmentalization and transmission of multiple epstein-barr virus strains in asymptomatic carriersQ24541318
Epstein-Barr virus infection in ex vivo tonsil epithelial cell cultures of asymptomatic carriersQ24561854
The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaBQ24646694
Epstein-Barr virus and virus human protein interaction mapsQ24675055
Structural and Mechanistic Insights into the Tropism of Epstein-Barr VirusQ26752331
Adoptive T-Cell ImmunotherapyQ26782845
Microvesicles and viral infectionQ26823408
Novel mechanisms of EBV-induced oncogenesisQ27006524
Therapeutic implications of Epstein-Barr virus infection for the treatment of nasopharyngeal carcinomaQ27016002
Epithelial-mesenchymal transitions in tumour progressionQ27860487
Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzeesQ27861060
Epstein–Barr Virus Replication in Oropharyngeal Epithelial CellsQ45796774
Chemical carcinogen Epstein-Barr virus (EBV) synergism: EBV genome amplification and site-specific mutation during transformationQ45846486
Epstein-Barr virus infection and replication in a human epithelial cell systemQ45880200
Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entryQ47239784
Cadherin 6 is activated by Epstein-Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinomaQ47248660
Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus.Q47559100
Well-differentiated human airway epithelial cell cultures.Q47910046
The NPC derived C15 LMP1 protein confers enhanced activation of NF-kappa B and induction of the EGFR in epithelial cells.Q48038156
C-Terminal Farnesylation of UCH-L1 Plays a Role in Transport of Epstein-Barr Virus Primary Oncoprotein LMP1 to ExosomesQ50045673
The interactome of EBV LMP1 evaluated by proximity-based BioID approachQ50064513
Viral Entry.Q50955999
The association of E-cadherin expression and the methylation status of the E-cadherin gene in nasopharyngeal carcinoma cells.Q54773119
Epstein-Barr virus-associated lymphomasQ56930876
Oral hairy leukoplakiaQ68465807
Conserved CTL epitopes within EBV latent membrane protein 2: a potential target for CTL-based tumor therapyQ73271294
Downregulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasisQ77340409
Exosomal communication goes viralQ28083133
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteinsQ28117120
Cadherin switch in tumor progressionQ28262569
Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activationQ28728022
MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger DatasetsQ29616345
Epstein-Barr virus: 40 years onQ29617969
Exosomes derived from Burkitt's lymphoma cell lines induce proliferation, differentiation, and class-switch recombination in B cellsQ30587658
EBV latent membrane protein 1 activates Akt, NFkappaB, and Stat3 in B cell lymphomasQ30837949
Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9Q33265945
Linkage between STAT regulation and Epstein-Barr virus gene expression in tumorsQ33866046
Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.Q33900772
VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT'S LYMPHOMAQ33971399
The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferasesQ34099074
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomesQ34171808
Genomic sequence analysis of Epstein-Barr virus strain GD1 from a nasopharyngeal carcinoma patientQ34228526
The DNA damage response in viral-induced cellular transformationQ34246710
Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsy samples.Q34262322
Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy.Q34271121
Human tumor virus utilizes exosomes for intercellular communication.Q34377767
LMP1 structure and signal transductionQ34415978
Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutationsQ34549536
Epstein-Barr virus replicating in epithelial cellsQ34581119
Efficient replication of Epstein-Barr virus in stratified epithelium in vitroQ34581330
Resting B cells as a transfer vehicle for Epstein-Barr virus infection of epithelial cellsQ34598541
LMP1-induced cell death may contribute to the emergency of its oncogenic property.Q34699997
LMP1 strain variants: biological and molecular properties.Q34717145
Epstein-Barr Virus latent membrane protein 1 induces Snail and epithelial-mesenchymal transition in metastatic nasopharyngeal carcinomaQ34745799
Signalling shortcuts: cell-surface receptors in the nucleus?Q34810206
Epstein-Barr virus in the pathogenesis of NPC.Q35008870
The significance of LMP1 expression in nasopharyngeal carcinomaQ35008886
Efficient immortalization of primary nasopharyngeal epithelial cells for EBV infection studyQ35027926
Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cellsQ35119824
Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signalingQ35122447
Direct sequencing and characterization of a clinical isolate of Epstein-Barr virus from nasopharyngeal carcinoma tissue by using next-generation sequencing technologyQ35363383
MUC1 induced by Epstein-Barr virus latent membrane protein 1 causes dissociation of the cell-matrix interaction and cellular invasiveness via STAT signalingQ35635449
The pathogenesis of Epstein-Barr virus persistent infection.Q38107595
The role of Epstein-Barr virus in epithelial malignanciesQ38253914
Characterization of the latent membrane protein 1 signaling complex of Epstein-Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementationQ38427527
Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinomaQ38480025
Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Types.Q38596342
Nasopharyngeal Carcinoma: An Evolving Role for the Epstein-Barr VirusQ38596356
Viral effects on the content and function of extracellular vesicles.Q38666881
CD63 Regulates Epstein-Barr Virus LMP1 Exosomal Packaging, Enhancement of Vesicle Production, and Noncanonical NF-κB SignalingQ38782732
Epstein-Barr virus LMP1 induces focal adhesions and epithelial cell migration through effects on integrin-α5 and N-cadherinQ38826798
Epstein-Barr virus latent membrane protein 1 genetic variability in peripheral blood B cells and oropharyngeal fluidsQ38855080
The genomic landscape of nasopharyngeal carcinomaQ38982367
The Long and Complicated Relationship between Epstein-Barr Virus and Epithelial CellsQ38994418
Complete genomic sequence of Epstein-Barr virus in nasopharyngeal carcinoma cell line C666-1.Q39115333
Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells.Q39124304
Cell-to-cell contact as an efficient mode of Epstein-Barr virus infection of diverse human epithelial cellsQ39578660
Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdeltaQ39595269
Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways.Q39604074
Endogenous latent membrane protein 1 in Epstein-Barr virus-infected nasopharyngeal carcinoma cells attracts T lymphocytes through upregulation of multiple chemokinesQ39679329
Preferential localization of the Epstein-Barr virus (EBV) oncoprotein LMP-1 to nuclei in human T cells: implications for its role in the development of EBV genome-positive T-cell lymphomasQ39683197
Identification of Epstein-Barr virus strain variants in hairy leukoplakia and peripheral blood by use of a heteroduplex tracking assayQ39684889
A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.Q39736828
Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization.Q39749474
Features distinguishing Epstein-Barr virus infections of epithelial cells and B cells: viral genome expression, genome maintenance, and genome amplificationQ39852028
Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.Q39917652
Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinomaQ39952661
Epstein-Barr virus infection and nasopharyngeal carcinomaQ40046633
HPV16 E7 Genetic Conservation Is Critical to CarcinogenesisQ40050669
A new diagnostic marker for secreted Epstein-Barr virus encoded LMP1 and BARF1 oncoproteins in the serum and saliva of patients with nasopharyngeal carcinomaQ40085468
Molecular diversity of IgG responses to Epstein-Barr virus proteins in asymptomatic Epstein-Barr virus carriersQ40088154
Epstein-Barr virus latent membrane protein 1 promotes concentration in multivesicular bodies of fibroblast growth factor 2 and its release through exosomesQ40124366
Genome-Wide Analysis of 18 Epstein-Barr Viruses Isolated from Primary Nasopharyngeal Carcinoma Biopsy SpecimensQ40150612
Biological and biochemical observations on isolates of EB virus from the malignant epithelial cells of two nasopharyngeal carcinomasQ40259681
Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cellsQ40293195
Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial CellsQ40339509
Epstein-Barr virus latent membrane protein 1 CTAR1 mediates rodent and human fibroblast transformation through activation of PI3K.Q40399583
Generation and Infection of Organotypic Cultures with Epstein-Barr VirusQ40441067
Nuclear accumulation of epidermal growth factor receptor and acceleration of G1/S stage by Epstein-Barr-encoded oncoprotein latent membrane protein 1.Q40470698
Epstein-Barr virus immortalizing genesQ40540784
Phenotypic alterations induced by the Hong Kong-prevalent Epstein-Barr virus-encoded LMP1 variant (2117-LMP1) in nasopharyngeal epithelial cellsQ40577418
The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activityQ40814583
Direct immunosuppressive effects of EBV-encoded latent membrane protein 1.Q40870284
CTL control of EBV in nasopharyngeal carcinoma (NPC): EBV-specific CTL responses in the blood and tumors of NPC patients and the antigen-processing function of the tumor cellsQ40872749
Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strainsQ40936386
Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 productionQ40951743
Functional analysis of different LMP1 proteins isolated from Epstein-Barr virus-positive carriersQ40957203
Epstein-Barr virus genotypes associated with nasopharyngeal carcinoma in southern ChinaQ41729450
Epstein-Barr virus latent membrane protein 1 modulates distinctive NF- kappaB pathways through C-terminus-activating region 1 to regulate epidermal growth factor receptor expressionQ41981419
Etiological factors of nasopharyngeal carcinomaQ42231417
Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomasQ42262852
Fibronectin overexpression is associated with latent membrane protein 1 expression and has independent prognostic value for nasopharyngeal carcinomaQ42265650
The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferationQ43610021
Persistent productive Epstein-Barr virus replication in normal epithelial cells in vivoQ43820693
Burkitt lymphoma and the discovery of Epstein-Barr virusQ43953860
Biology of Epstein-Barr virus during infectious mononucleosisQ43971482
Expression of Epstein‐Barr virus‐encodedLMP1andhTERTextends the life span and immortalizes primary cultures of nasopharyngeal epithelial cellsQ44232903
Expression of Epstein-Barr virus latent genes in oral epithelium: determinants of the pathogenesis of oral hairy leukoplakiaQ44929567
Persistence and transition of Epstein-Barr virus genotypes in the pathogenesis of oral hairy leukoplakiaQ44951056
Latent Membrane Protein 1 Is a Novel Determinant of Epstein-Barr Virus Genome Persistence and ReactivationQ45288192
Tetraspanin CD63 bridges autophagic and endosomal processes to regulate exosomal secretion and intracellular signaling of Epstein-Barr virus LMP1.Q45323701
Effective treatment of metastatic forms of Epstein-Barr virus-associated nasopharyngeal carcinoma with a novel adenovirus-based adoptive immunotherapyQ45360118
Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma.Q45360289
Epstein-Barr virus (EBV) infection in epithelial cells in vivo: rare detection of EBV replication in tongue mucosa but not in salivary glandsQ45532916
Epstein-Barr virus strain variation in nasopharyngeal carcinoma from the endemic and non-endemic regions of ChinaQ45756839
Analysis of Epstein-Barr virus infection in nasopharyngeal biopsies from a group at high risk of nasopharyngeal carcinoma.Q45775433
Sequence variation in the Epstein-Barr virus latent membrane protein 1.Q45782895
Epstein-Barr virus is detected in undifferentiated nasopharyngeal carcinoma but not in lymphoepithelioma-like carcinoma of the urinary bladderQ45788362
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infectionQ35641421
Focus on nasopharyngeal carcinomaQ35773862
Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial CellsQ35797164
Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Variants of Epstein-Barr virus-infected neoplasiaQ35798133
The Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor.Q35841701
The Epstein-Barr virus 3.5-kilobase latent membrane protein 1 mRNA initiates from a TATA-Less promoter within the first terminal repeatQ35842451
LMP1-Induced Sumoylation Influences the Maintenance of Epstein-Barr Virus Latency through KAP1Q35861199
Regulation of DNA Damage Signaling and Cell Death Responses by Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) and LMP2A in Nasopharyngeal Carcinoma Cells.Q35861281
The role of miRNAs and EBV BARTs in NPC.Q35924359
The expression of matrix metalloproteinase 9 is enhanced by Epstein-Barr virus latent membrane protein 1Q36006767
Nonmuscle myosin heavy chain IIA mediates Epstein-Barr virus infection of nasopharyngeal epithelial cellsQ36055637
Epstein-Barr virus latent membrane protein 1 regulates the function of interferon regulatory factor 7 by inducing its sumoylationQ36363843
Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cellsQ36483613
The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signallingQ36500037
Whole-genome sequencing of the Akata and Mutu Epstein-Barr virus strainsQ36559612
Epstein-Barr virus LMP1 modulates lipid raft microdomains and the vimentin cytoskeleton for signal transduction and transformationQ36559750
Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformationQ36575274
Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinomaQ36742929
Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genesQ36782491
Potential selection of LMP1 variants in nasopharyngeal carcinomaQ36944141
EBV latent membrane protein 1 effects on plakoglobin, cell growth, and migration.Q36994005
Immortalization of human lymphocytes by Epstein-Barr virusQ37000329
Human airway epithelial cell culture to identify new respiratory viruses: coronavirus NL63 as a modelQ37165380
Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.Q37323204
Epstein-Barr Virus encoded LMP1 regulates cyclin D1 promoter activity by nuclear EGFR and STAT3 in CNE1 cellsQ37350214
Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch.Q37408369
Fusion of epithelial cells by Epstein-Barr virus proteins is triggered by binding of viral glycoproteins gHgL to integrins alphavbeta6 or alphavbeta8.Q37453542
Role of the Epstein-Barr virus-encoded latent membrane protein-1, LMP1, in the pathogenesis of nasopharyngeal carcinomaQ37575613
Culturing of human nasal epithelial cells at the air liquid interfaceQ37610749
STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferationQ37687614
The biological properties of different Epstein-Barr virus strains explain their association with various types of cancersQ37705818
Epstein-Barr virus genetics: talking about the BAC generationQ37856451
The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC).Q37976235
The biology of EBV infection in human epithelial cellsQ38002035
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P577publication date2018-03-21
P1433published inCancersQ27722963
P1476titleNew Insights from Elucidating the Role of LMP1 in Nasopharyngeal Carcinoma.
P478volume10

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cites work (P2860)
Q57093338Air-Liquid Interface Method To Study Epstein-Barr Virus Pathogenesis in Nasopharyngeal Epithelial Cells
Q64084471Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway
Q64901933Efficient Epstein-Barr Virus Progeny Production Mediated by Cancer-Derived LMP1 and Virally-Encoded microRNAs.
Q56990996Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck Cancer
Q59358007Modified Anoikis Assay That Functionally Segregates Epstein-Barr Virus LMP1 Strains into Two Groups