Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies

scientific article

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1024008605
P356DOI10.1007/S00401-009-0635-8
P932PMC publication ID2849937
P698PubMed publication ID20091409
P5875ResearchGate publication ID41103724

P50authorJohn T. O'BrienQ37830687
Masafumi IharaQ42656310
Paul InceQ42856560
Elisabet EnglundQ56589972
P2093author name stringRaj N Kalaria
Robert H Perry
Arthur E Oakley
Tuomo M Polvikoski
Ros Hall
Janet Y Slade
P2860cites workNeuropathological stageing of Alzheimer-related changesQ27860862
Diagnosis and management of dementia with Lewy bodies: third report of the DLB ConsortiumQ29614409
Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia.Q30813216
Changes in DWI and MRS associated with white matter hyperintensities in elderly subjects.Q30882166
Glial levels determine severity of white matter disease in Alzheimer's disease: a neuropathological study of glial changes.Q30908254
Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe ConsortiumQ34023599
Axonal damage: a key predictor of outcome in human CNS diseasesQ34174912
The Significance of Cerebral White Matter Abnormalities 100 Years After Binswanger’s ReportQ34299420
Alterations in glia and axons in the brains of Binswanger's disease patientsQ34433021
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistryQ34556945
Similarities between Alzheimer's disease and vascular dementiaQ34989464
Rett Syndrome -- an updateQ35136636
White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer's disease, vascular dementia, and normal agingQ35451667
Quantitative MRI findings and cognitive impairment among community dwelling elderly subjectsQ35467851
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigensQ35764331
Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's diseaseQ35774045
White matter lesions impair frontal lobe function regardless of their locationQ35844738
Towards defining the neuropathological substrates of vascular dementia.Q35945432
The enigma of vascular cognitive disorder and vascular dementiaQ36730292
Neuropathological correlates of temporal pole white matter hyperintensities in CADASIL.Q37299626
Pathogenesis of leukoaraiosis: a reviewQ41369515
Cerebral vessels in ageing and Alzheimer's diseaseQ41639782
Medullary arteries in aging and dementiaQ44347066
Upregulation of oligodendrocyte progenitor cells associated with restoration of mature oligodendrocytes and myelination in peri-infarct area in the rat brainQ44616090
Progression of white matter hyperintensities in Alzheimer disease, dementia with lewy bodies, and Parkinson disease dementia: a comparison with normal agingQ44668515
Encephalitogenic peptide (EP) in human cerebrovascular white matter lesionsQ46160481
Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's diseaseQ46825969
Topographical and cytopathological lesion analysis of the white matter in Binswanger's disease brainsQ47753395
Prevalence of vascular lesions in dementia with Lewy bodies. A postmortem study.Q47824887
Neuropathology of white matter changes in Alzheimer's disease and vascular dementia.Q48406159
Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI studyQ48424981
Nogo-A expression in the human hippocampus in normal aging and in Alzheimer diseaseQ48497710
Phases of A beta-deposition in the human brain and its relevance for the development of AD.Q48567985
White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injuryQ48575517
The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: a commentaryQ48662464
Axonal damage and demyelination in the white matter after chronic cerebral hypoperfusion in the rat.Q48689416
A Pi Form of Glutathione-S-Transferase Is a Myelin-and Oligodendrocyte-Associated Enzyme in Mouse BrainQ48702530
Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomasQ48743716
Decreasing myelin density reflected increasing white matter pathology in Alzheimer's disease--a neuropathological studyQ48767861
Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brainQ48825929
Heterogeneity of white matter hyperintensities in Alzheimer's disease: post-mortem quantitative MRI and neuropathology.Q48876836
Age-related alterations in white matter microstructure measured by diffusion tensor imagingQ48884470
Brain tissue damage in dementia with Lewy bodies: an in vivo diffusion tensor MRI studyQ48937236
Diffuse vacuolization (spongiosis) and arteriolosclerosis in the frontal white matter occurs in vascular dementiaQ49017095
Differential degeneration of the cerebral microvasculature in Alzheimer's disease.Q53202611
Clinical Lewy body dementia and the impact of vascular components.Q53232551
Myelin breakdown in Alzheimer's disease: a commentary.Q53259065
Differential deposition of amyloid beta peptides in cerebral amyloid angiopathy associated with Alzheimer's disease and vascular dementia.Q53378017
White Matter Hyperintensities Are Associated With Impairment of Memory, Attention, and Global Cognitive Performance in Older Stroke PatientsQ57813866
Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosisQ73302186
Neuropathological correlates to clinically defined dementia with Lewy bodiesQ74245351
P433issue5
P921main subjectAlzheimer's diseaseQ11081
dementiaQ83030
vascular dementiaQ583908
dementia with Lewy bodiesQ101245788
P304page(s)579-589
P577publication date2010-01-21
P1433published inActa NeuropathologicaQ343168
P1476titleQuantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies
P478volume119

Reverse relations

cites work (P2860)
Q64124512A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology
Q59543627Adrenomedullin, a Novel Target for Neurodegenerative Diseases
Q45841436Age-dependent modification of proteins: N-terminal racemization
Q49294109An Aged Canid with Behavioral Deficits Exhibits Blood and Cerebrospinal Fluid Amyloid Beta Oligomers
Q37517131Aspirin promotes oligodendrocyte precursor cell proliferation and differentiation after white matter lesion
Q55415412Association between Alzheimer's disease pathogenesis and early demyelination and oligodendrocyte dysfunction.
Q46985283Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms
Q38020618Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.
Q38232821Axonal transport defects in Alzheimer's disease
Q35767208Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts
Q47651485Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases
Q34275469Decreased oligodendrocyte nuclear diameter in Alzheimer's disease and Lewy body dementia
Q44839334Dementia: Vascular and neurodegenerative pathways-will they meet?
Q50547160Disrupted white matter structure underlies cognitive deficit in hypertensive patients.
Q59798063Dysfunction of Cerebrovascular Endothelial Cells: Prelude to Vascular Dementia
Q35852601Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion
Q47417382Effect of ninjin'yoeito, a Kampo (traditional Japanese) medicine, on cognitive impairment and depression in patients with Alzheimer's disease: 2 years of observation
Q48656776Effects of Chronic Scopolamine Treatment on Cognitive Impairments and Myelin Basic Protein Expression in the Mouse Hippocampus
Q36684570Effects of Hormone Therapy on Brain Volumes Changes of Postmenopausal Women Revealed by Optimally-Discriminative Voxel-Based Morphometry
Q91955237Elevated Insulin and Insulin Resistance are Associated with Altered Myelin in Cognitively Unimpaired Middle-Aged Adults
Q92636791Emerging Biomarkers in Vascular Cognitive Impairment and Dementia: From Pathophysiological Pathways to Clinical Application
Q48361042Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry.
Q34370861Frontal lobe white matter hyperintensities and neurofibrillary pathology in the oldest old.
Q35868696Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia
Q36694586Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease
Q99711219HUCBC Treatment Improves Cognitive Outcome in Rats With Vascular Dementia
Q38748464Heterozygote galactocerebrosidase (GALC) mutants have reduced remyelination and impaired myelin debris clearance following demyelinating injury
Q52330247Heterozygous carriers of galactocerebrosidase mutations that cause Krabbe disease have impaired microglial function and defective repair of myelin damage.
Q39114617Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes
Q35606711Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors
Q48773470Longitudinal magnetization transfer imaging in mild to severe Alzheimer disease
Q89522904Microbleeds in dementia with Lewy bodies
Q92423945Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
Q26824027Microvascular pathology and morphometrics of sporadic and hereditary small vessel diseases of the brain
Q48103598Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease
Q36244982Models and mechanisms of vascular dementia
Q36595660Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias
Q48251767Myelin Detection Using Rapid Quantitative MR Imaging Correlated to Macroscopically Registered Luxol Fast Blue-Stained Brain Specimens
Q90011417Myelin Measurement: Comparison Between Simultaneous Tissue Relaxometry, Magnetization Transfer Saturation Index, and T1w/T2w Ratio Methods
Q35576628Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain
Q33791342Myelin injury and degraded myelin vesicles in Alzheimer's disease
Q41069446Neuroinflammation, myelin and behavior: Temporal patterns following mild traumatic brain injury in mice
Q26750515Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease
Q60917211Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain
Q38497880Oligodendrocytes and Alzheimer's disease
Q36754568Pathology and pathogenesis of vascular cognitive impairment-a critical update
Q38730474Pathology of the Aging Brain in Domestic and Laboratory Animals, and Animal Models of Human Neurodegenerative Diseases
Q48194042Pericyte-derived bone morphogenetic protein 4 underlies white matter damage after chronic hypoperfusion
Q28394779Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain
Q37387274Protective effects of carnosine on white matter damage induced by chronic cerebral hypoperfusion.
Q48689999Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias
Q47324557Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.
Q38814687Remyelination: A Potential Therapeutic Strategy for Alzheimer's Disease?
Q35865696Staging and natural history of cerebrovascular pathology in dementia
Q36786383Stroke injury, cognitive impairment and vascular dementia
Q33964442Structural covariance of superficial white matter in mild Alzheimer's disease compared to normal aging.
Q36341689TREM2 regulates microglial cell activation in response to demyelination in vivo
Q46788633Tau proteins in the temporal and frontal cortices in patients with vascular dementia.
Q50593514The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion.
Q47136067The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease
Q38969718The impact of cerebrovascular aging on vascular cognitive impairment and dementia.
Q34402033The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia
Q34484708The overlap between vascular disease and Alzheimer's disease--lessons from pathology
Q36731049The role of cerebrovascular disease when there is concomitant Alzheimer disease
Q48691605Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.
Q36127395Traumatic brain injury in young rats leads to progressive behavioral deficits coincident with altered tissue properties in adulthood
Q38238144Understanding and preventing the development of post-stroke dementia
Q47964631Update on Vascular Dementia
Q61797709White matter capillaries in vascular and neurodegenerative dementias
Q30880445White matter changes in dementia: role of impaired drainage of interstitial fluid.
Q47325037White matter degeneration in vascular and other ageing-related dementias
Q34515561White matter hyperintensities and imaging patterns of brain ageing in the general population
Q33864697White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults.
Q33741447White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease
Q34805975White matter pathology and disconnection in the frontal lobe in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Search more.