| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Michael Chopp | Q71037672 |
| P2093 | author name string | Jieli Chen | |
| Poornima Venkat | |||
| P2860 | cites work | Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults | Q24558984 |
| Vascular dementia | Q24629003 | ||
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| High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling | Q30496730 | ||
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| Middle-aged, but not young, rats develop cognitive impairment and cortical neurodegeneration following the four-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion. | Q44173545 | ||
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| Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats | Q44923040 | ||
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| The metabolic syndrome, inflammation, and risk of cognitive decline | Q45145786 | ||
| An experimental model of lacunar infarction: embolization of microthrombi | Q45332918 | ||
| Injury markers in two models of cerebral ischemia | Q45416345 | ||
| Effects of statins on the progression of cerebral white matter lesion: Post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study | Q46104218 | ||
| Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes. | Q46223207 | ||
| High blood pressure and cerebral white matter lesion progression in the general population | Q46400752 | ||
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| Inhibitory avoidance memory retention in the elevated T-maze is impaired after perivascular manipulation of the common carotid arteries | Q46434959 | ||
| Effect of age on hypertension: analysis of over 4,800 referred hypertensive patients. | Q46652070 | ||
| Effects of acupuncture on declined cerebral blood flow, impaired mitochondrial respiratory function and oxidative stress in multi-infarct dementia rats | Q46824636 | ||
| Complex neurodegeneration in retina following moderate ischemia induced by bilateral common carotid artery occlusion in Wistar rats | Q46855125 | ||
| Strain differences in fatigue and depression after experimental stroke | Q46881379 | ||
| Amelioration of cognitive impairment in the type-2 diabetic mouse by the angiotensin II type-1 receptor blocker candesartan | Q46925507 | ||
| Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice | Q47961075 | ||
| Pathology and pathophysiology of cerebrovascular dementia: pure subgroups of obstructive and hypoperfusive etiology | Q48128525 | ||
| Depressive-like behaviors in a rat model of chronic cerebral hypoperfusion | Q48145468 | ||
| Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats | Q48194377 | ||
| Glial activation and white matter changes in the rat brain induced by chronic cerebral hypoperfusion: an immunohistochemical study | Q48212602 | ||
| Sustained decrease in brain regional blood flow after microsphere embolism in rats | Q48323254 | ||
| Blood-brain barrier disruption in white matter lesions in a rat model of chronic cerebral hypoperfusion | Q42516218 | ||
| The long-term efficacy and tolerability of donepezil in patients with vascular dementia | Q42628342 | ||
| Microemboli composed of cholesterol crystals disrupt the blood-brain barrier and reduce cognition | Q42659740 | ||
| A high-fat diet impairs neurogenesis: Involvement of lipid peroxidation and brain-derived neurotrophic factor | Q42952281 | ||
| A mouse model characterizing features of vascular dementia with hippocampal atrophy | Q43071462 | ||
| Metabolic syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Ageing | Q43228795 | ||
| Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion | Q43268776 | ||
| Association between dementia and midlife risk factors: the Radiation Effects Research Foundation Adult Health Study | Q43447590 | ||
| Cerebral embolization leads to memory impairment of several learning tasks in rats | Q43485821 | ||
| Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study | Q43935519 | ||
| Retinal and optic nerve degeneration after chronic carotid ligation: time course and role of light exposure | Q43948964 | ||
| Sildenafil provides sustained neuroprotection in the absence of learning recovery following the 4-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion in middle-aged rats | Q48375736 | ||
| Pathogenetic similarity of strokes in stroke-prone spontaneously hypertensive rats and humans | Q48408803 | ||
| Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents. | Q48410331 | ||
| Effect of simvastatin on MMPs and TIMPs in human brain endothelial cells and experimental stroke | Q48423590 | ||
| The effect of simvastatin treatment on behavioral parameters, cognitive performance, and hippocampal morphology in rats fed a standard or a high-fat diet | Q48439680 | ||
| Persistent impairment of gait performances and working memory after bilateral common carotid artery occlusion in the adult Wistar rat. | Q48465637 | ||
| Late-life metabolic syndrome prevents cognitive decline among older men aged 75 years and over: one-year prospective cohort study | Q48466562 | ||
| Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability | Q48573786 | ||
| Hippocampal (CA1) activities in Wistar rats from different vendors. Fundamental differences in acute ischemia | Q48580931 | ||
| The dose-response effect of acute intravenous transplantation of human umbilical cord blood cells on brain damage and spatial memory deficits in neonatal hypoxia-ischemia | Q48601887 | ||
| Evaluation of the protective potential of brain microvascular endothelial cell autophagy on blood-brain barrier integrity during experimental cerebral ischemia-reperfusion injury | Q48633024 | ||
| Adverse effects associated with the use of donepezil in general practice in England | Q48703804 | ||
| Failure in learning task and loss of cortical cholingergic fibers in microsphere-embolized rats | Q48736410 | ||
| Permanent, 3-stage, 4-vessel occlusion as a model of chronic and progressive brain hypoperfusion in rats: a neurohistological and behavioral analysis | Q48906654 | ||
| Dietary resveratrol supplementation normalizes gene expression in the hippocampus of streptozotocin-induced diabetic C57Bl/6 mice. | Q50663969 | ||
| Comparison of cognitive performance between two rat models of vascular dementia. | Q50697773 | ||
| Protective effect of bilobalide on learning and memory impairment in rats with vascular dementia. | Q50735049 | ||
| Association of cerebral emboli with accelerated cognitive deterioration in Alzheimer's disease and vascular dementia. | Q50775712 | ||
| Metabolic syndrome is associated with poor memory and executive performance in elderly community residents: the PROOF study. | Q50860432 | ||
| Blood pressure reduction, cardiovascular diseases, and cognitive decline in the mini-mental state examination in a community population of normal very old people: a three-year follow-up. | Q50883499 | ||
| Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion. | Q50889759 | ||
| Selective white matter abnormalities in a novel rat model of vascular dementia. | Q50980121 | ||
| Decline in blood pressure over time and risk of dementia: a longitudinal study from the Kungsholmen project. | Q51939508 | ||
| The hippocampus in spontaneously hypertensive rats: an animal model of vascular dementia? | Q52014470 | ||
| Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia. | Q52125344 | ||
| [Availability of 2VO rats as a model for chronic cerebrovascular disease]. | Q52177891 | ||
| Diabetes mellitus and the risk of dementia: The Rotterdam Study. | Q53231897 | ||
| Midlife blood pressure and dementia: the Honolulu-Asia aging study. | Q53234678 | ||
| Midlife blood pressure and the risk of hippocampal atrophy: the Honolulu Asia Aging Study. | Q53261918 | ||
| Predictors of cognitive impairment and dementia in older people with diabetes. | Q53290887 | ||
| Prevention of Spontaneous Tumors of Aged Mice by Immunopharmacologic Manipulation: Study of Immune Antitumor Mechanisms2 | Q58106121 | ||
| The four-vessel occlusion rat model: method for complete occlusion of vertebral arteries and control of collateral circulation | Q68147230 | ||
| Blood pressure and cognitive performance. The Framingham Study | Q69461525 | ||
| Memory deficit accompanying cerebral neurodegeneration after stroke in stroke-prone spontaneously hypertensive rats (SHRSP) | Q72846927 | ||
| Clinical management of metabolic syndrome: report of the American Heart Association/National Heart, Lung, and Blood Institute/American Diabetes Association conference on scientific issues related to management | Q75392143 | ||
| [Changes of interleukin-1beta and TNF-alpha contents in the hippocampus and the interventional effect of electroacupuncture in vascular dementia rats] | Q80502775 | ||
| Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain | Q33281864 | ||
| Chronic cerebral hypoperfusion induced by right unilateral common carotid artery occlusion causes delayed white matter lesions and cognitive impairment in adult mice | Q33316614 | ||
| Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair | Q33583258 | ||
| Association between risk factors for vascular dementia and adiponectin | Q33594133 | ||
| Cognitive impairment following high fat diet consumption is associated with brain inflammation. | Q33665160 | ||
| Mesenchymal stem cells can modulate longitudinal changes in cortical thickness and its related cognitive decline in patients with multiple system atrophy. | Q33750881 | ||
| Hypertension-induced vascular remodeling contributes to reduced cerebral perfusion and the development of spontaneous stroke in aged SHRSP rats | Q33766305 | ||
| Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies | Q33771165 | ||
| Neurorestorative therapy for stroke | Q33813333 | ||
| Is apolipoprotein E4 an important risk factor for vascular dementia? | Q34028845 | ||
| Dietary fat intake and the risk of incident dementia in the Rotterdam Study | Q34065622 | ||
| Brain aging and AD-like pathology in streptozotocin-induced diabetic rats | Q34114295 | ||
| Effects of nefiracetam on spatial memory function and acetylcholine and GABA metabolism in microsphere-embolized rats | Q34155664 | ||
| Myelin loss associated with neuroinflammation in hypertensive rats | Q34169644 | ||
| Accelerated progression from mild cognitive impairment to dementia in people with diabetes | Q34237746 | ||
| The use of animal models in diabetes research | Q34255921 | ||
| HUCBCs increase angiopoietin 1 and induce neurorestorative effects after stroke in T1DM rats | Q34270300 | ||
| Comparison of different diagnostic criteria for vascular dementia (ADDTC, DSM-IV, ICD-10, NINDS-AIREN). | Q34370559 | ||
| Blood pressure and dementia - a comprehensive review | Q34409397 | ||
| Prevalence of dementia in the United States: the aging, demographics, and memory study. | Q34584456 | ||
| Microinfarct pathology, dementia, and cognitive systems | Q34590151 | ||
| Vascular pathology and blood-brain barrier disruption in cognitive and psychiatric complications of type 2 diabetes mellitus | Q34590922 | ||
| Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test | Q34657450 | ||
| Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study | Q34866029 | ||
| Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials | Q34972793 | ||
| Remote ischemic postconditioning: harnessing endogenous protection in a murine model of vascular cognitive impairment | Q34979871 | ||
| Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memory | Q34990621 | ||
| White matter damage and the effect of matrix metalloproteinases in type 2 diabetic mice after stroke | Q35025916 | ||
| Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment | Q35059041 | ||
| Perfusion of ischemic brain in young and aged animals: a laser speckle flowmetry study | Q35072419 | ||
| Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic tolerance | Q35810317 | ||
| TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation. | Q35818467 | ||
| Therapeutic benefit of treatment of stroke with simvastatin and human umbilical cord blood cells: neurogenesis, synaptic plasticity, and axon growth | Q36235193 | ||
| Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long-term follow up study | Q36244107 | ||
| Studies of the effects of high fat diets on cognitive function in a rat model | Q36283934 | ||
| Diabetes mellitus and stroke | Q36366998 | ||
| Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts | Q36521047 | ||
| Interleukin-1β accelerates the onset of stroke in stroke-prone spontaneously hypertensive rats. | Q36522750 | ||
| Multiple low-dose infusions of human umbilical cord blood cells improve cognitive impairments and reduce amyloid-β-associated neuropathology in Alzheimer mice | Q36547428 | ||
| Low blood pressure and dementia in elderly people: the Kungsholmen project | Q36598015 | ||
| Effects of sinapic Acid of 4 vessel occlusion model-induced ischemia and cognitive impairments in the rat. | Q36600557 | ||
| Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases | Q36734195 | ||
| Blood brain barrier breakdown as the starting point of cerebral small vessel disease? - New insights from a rat model. | Q36744727 | ||
| TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets. | Q36956811 | ||
| Metabolic syndrome and risk for incident Alzheimer's disease or vascular dementia: the Three-City Study | Q37022797 | ||
| Low cerebral blood flow is associated with lower memory function in metabolic syndrome | Q37093208 | ||
| Divergent role for MMP-2 in myelin breakdown and oligodendrocyte death following transient global ischemia | Q37108870 | ||
| Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. | Q37222582 | ||
| Different patterns of cerebral injury in dementia with or without diabetes | Q37397970 | ||
| Pathophysiology of vascular dementia | Q37443340 | ||
| TLR4-dependent metabolic changes are associated with cognitive impairment in an animal model of type 1 diabetes | Q37562669 | ||
| Chronic cerebral hypoperfusion causes decrease of O-GlcNAcylation, hyperphosphorylation of tau and behavioral deficits in mice | Q37570868 | ||
| Inter-relationships among diet, obesity and hippocampal-dependent cognitive function. | Q37603549 | ||
| The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. | Q37634991 | ||
| Apolipoprotein E pathology in vascular dementia | Q37676723 | ||
| Linking oxidative stress to inflammation: Toll-like receptors | Q37677270 | ||
| Pathophysiology of white matter perfusion in Alzheimer's disease and vascular dementia | Q37723412 | ||
| Cerebral hypoperfusion and cognitive impairment: the pathogenic role of vascular oxidative stress | Q38004086 | ||
| Excitotoxicity and stroke: identifying novel targets for neuroprotection. | Q38173189 | ||
| Neurogenesis in neurological and psychiatric diseases and brain injury: from bench to bedside. | Q38175268 | ||
| Metabolic syndrome and longitudinal changes in cognitive function: a systematic review and meta-analysis | Q38191801 | ||
| Impact of metabolic syndrome on cognitive decline in older age: protective or harmful, where is the pitfall? | Q38193309 | ||
| Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes | Q39114617 | ||
| A new model of bilateral hemispheric ischemia in the unanesthetized rat | Q39259932 | ||
| Evaluation of hippocampal injury and cognitive function induced by embolization in the rat brain | Q39409049 | ||
| Risk of dementia among persons with diabetes mellitus: a population-based cohort study | Q39441115 | ||
| Vascular risk factors and dementia: 40-year follow-up of a population-based cohort | Q39724494 | ||
| Long-lasting functional disabilities in middle-aged rats with small cerebral infarcts. | Q40545856 | ||
| Diabetes mellitus: an independent risk factor for stroke? | Q41437953 | ||
| Risk factors for lacunar infarction syndromes | Q41680330 | ||
| Resveratrol improves cognition and reduces oxidative stress in rats with vascular dementia | Q41986372 | ||
| Cerebrovascular permeability and cognition in the aging rat | Q42459604 | ||
| Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia | Q42511032 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | dementia | Q83030 |
| P304 | page(s) | 97-108 | |
| P577 | publication date | 2015-05-15 | |
| P1433 | published in | Experimental Neurology | Q5421127 |
| P1476 | title | Models and mechanisms of vascular dementia | |
| P478 | volume | 272 |
| Q46256199 | A Mini-Review of the NADPH oxidases in Vascular Dementia: Correlation with NOXs and Risk Factors for VaD. |
| Q94464100 | A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment |
| Q91816056 | Animal Models of Chronic Cerebral Hypoperfusion: From Mouse to Primate |
| Q58085858 | CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses |
| Q47160388 | Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion. |
| Q47549771 | Correlation study of Framingham risk score and vascular dementia: An observational study |
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| Q28817091 | Dementia, Preclinical Studies in Neurodegeneration and its Potential for Translational Medicine in South America |
| Q39780738 | Depression and the risk of vascular dementia: a population-based retrospective cohort study |
| Q95642951 | ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia |
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| Q55381072 | Efficacy and safety of the compound Chinese medicine SaiLuoTong in vascular dementia: A randomized clinical trial. |
| Q90411315 | Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis |
| Q92636791 | Emerging Biomarkers in Vascular Cognitive Impairment and Dementia: From Pathophysiological Pathways to Clinical Application |
| Q92442235 | Emerging molecular mechanisms of vascular dementia |
| Q54979299 | Genome‑wide DNA methylation profiling in a rat model with vascular dementia. |
| Q92995831 | Glomerular hyperfiltration is associated with dementia: A nationwide population-based study |
| Q99711219 | HUCBC Treatment Improves Cognitive Outcome in Rats With Vascular Dementia |
| Q36623143 | Hypertension and aging |
| Q40383156 | Influence of pneumonia complications on the prognosis of patients with autopsy-confirmed Alzheimer's disease, dementia with Lewy bodies, and vascular dementia. |
| Q48003072 | L-3-n-Butylphthalide Activates Akt/mTOR Signaling, Inhibits Neuronal Apoptosis and Autophagy and Improves Cognitive Impairment in Mice with Repeated Cerebral Ischemia-Reperfusion Injury |
| Q47191829 | Lysophospholipid-Related Diseases and PPARγ Signaling Pathway. |
| Q55617506 | Molecular Mechanisms of Oligodendrocyte Regeneration in White Matter-Related Diseases. |
| Q38840105 | Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion? |
| Q40927656 | Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate. |
| Q26745457 | New insights into coupling and uncoupling of cerebral blood flow and metabolism in the brain |
| Q55283475 | Panax ginseng extract attenuates neuronal injury and cognitive deficits in rats with vascular dementia induced by chronic cerebral hypoperfusion. |
| Q90272984 | Possible mechanisms of lycopene amelioration of learning and memory impairment in rats with vascular dementia |
| Q45070410 | Potential Therapeutics for Vascular Cognitive Impairment and Dementia |
| Q42367390 | Protection of the brain through supplementation with larch arabinogalactan in a rat model of vascular dementia |
| Q47978630 | Sequential PET estimation of cerebral oxygen metabolism with spontaneous respiration of 15O-gas in mice with bilateral common carotid artery stenosis |
| Q38618330 | Short-term apparent brain tissue changes are contributed by cerebral blood flow alterations. |
| Q64057683 | Short-term auricular electrical stimulation rapidly elevated cortical blood flow and promoted the expression of nicotinic acetylcholine receptor α4 in the 2 vessel occlusion rats model |
| Q93185032 | Small vessel disease to subcortical dementia: a dynamic model, which interfaces aging, cholinergic dysregulation and the neurovascular unit |
| Q39164134 | Structural and functional brain alterations in a murine model of Angiotensin II-induced hypertension |
| Q41884186 | The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats |
| Q38969718 | The impact of cerebrovascular aging on vascular cognitive impairment and dementia. |
| Q33726628 | Towards the concept of disease-modifier in post-stroke or vascular cognitive impairment: a consensus report |
| Q47582397 | Umbilical cord-derived mesenchymal stem cell transplantation for treating elderly vascular dementia |
| Q30248800 | Using Multicountry Ecological and Observational Studies to Determine Dietary Risk Factors for Alzheimer's Disease |
| Q36767965 | Vascular cognitive impairment: Modeling a critical neurologic disease in vitro and in vivo |
| Q40430696 | White matter damage and glymphatic dysfunction in a model of vascular dementia in rats with no prior vascular pathologies |
| Q64082869 | decoction extract regulates differentially expressed proteins in the hippocampus after chronic cerebral hypoperfusion |
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