MUC1 and cancer

scientific article

MUC1 and cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0925-4439(99)00055-1
P698PubMed publication ID10571020
P5875ResearchGate publication ID12730260

P2093author name stringD W Miles
J Burchell
J Taylor-Papadimitriou
M Dalziel
P2860cites workSubstrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3Q24311744
Antibodies against mucin-associated sialyl-Tn epitopes correlate with survival of metastatic adenocarcinoma patients undergoing active specific immunotherapy with synthetic STn vaccineQ71659957
Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamideQ71699068
Fine specificity of antibody recognition of carcinoma-associated epithelial mucins: Antibody binding to synthetic peptide epitopesQ72067897
Alterations of O-glycan biosynthesis in human colon cancer tissuesQ72203074
Processing O-glycan core 1, Gal beta 1-3GalNAc alpha-R. Specificities of core 2, UDP-GlcNAc: Gal beta 1-3 GalNAc-R(GlcNAc to GalNAc) beta 6-N-acetylglucosaminyltransferase and CMP-sialic acid: Gal beta 1-3GalNAc-R alpha 3-sialyltransferaseQ72750319
Pharmacokinetics and toxicity of an yttrium-90-CITC-DTPA-HMFG1 radioimmunoconjugate for intraperitoneal radioimmunotherapy of ovarian cancerQ72768948
Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesinQ73300727
Low O-acetylation of sialyl-Le(x) contributes to its overexpression in colon carcinoma metastasesQ73503250
Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulationQ73562880
Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell linesQ73717919
Mucins (MUC1 and MUC3) of gastrointestinal and breast epithelia reveal different and heterogeneous tumor-associated aberrations in glycosylationQ73850281
Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2Q74033284
An enzyme-linked immunosorbent assay for the measurement of circulating antibodies to polymorphic epithelial mucin (MUC1)Q74559831
Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix componentsQ24312497
Cloning and expression of cDNA for a human Gal(beta1-3)GalNAc alpha2,3-sialyltransferase from the CEM T-cell lineQ24324122
Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat arrayQ24530913
Expression cloning of a cDNA encoding UDP-GlcNAc:Gal beta 1-3-GalNAc-R (GlcNAc to GalNAc) beta 1-6GlcNAc transferase by gene transfer into CHO cells expressing polyoma large tumor antigenQ24563666
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesionQ28237260
Innate immunity: the virtues of a nonclonal system of recognitionQ29614428
Oxidative/reductive conjugation of mannan to antigen selects for T1 or T2 immune responses.Q33820583
Three genes that encode human β-galactoside α2,3-sialyltransferases. Structural analysis and chromosomal mapping studiesQ34303681
Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cellsQ34304405
Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. German Cancer Aid 17-1A Study GroupQ34322325
Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.Q34411297
Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivoQ34440632
Mucin genes and the proteins they encode: structure, diversity, and regulationQ35537772
Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patientsQ36081647
A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycansQ36254705
99mTc-labelled SM3 in the preoperative evaluation of axillary lymph nodes and primary breast cancer with change detection statistical processing as an aid to tumour detectionQ36294993
CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunityQ36380885
Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion proteinQ37375709
Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cellsQ37396123
Determination of the site-specific O-glycosylation pattern of the porcine submaxillary mucin tandem repeat glycopeptide. Model proposed for the polypeptide:galnac transferase peptide binding siteQ38346855
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.Q40242537
MUC‐1 Epithelial Tumor Mucin‐Based Immunity and Cancer VaccinesQ40433320
Expression of B7.1 in a MUC1-expressing mouse mammary epithelial tumour cell line inhibits tumorigenicity but does not induce autoimmunity in MUC1 transgenic miceQ40934020
Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccineQ41065506
Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue.Q41444956
Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 geneQ41581624
Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapyQ41594089
Antibodies to the cytoplasmic domain of the MUC1 mucin show conservation throughout mammalsQ41623438
Structures of acidic O-linked polylactosaminoglycans on human skim milk mucinsQ44888350
Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma.Q47705298
Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptideQ47975807
Tissue-specific regulation of mouse core 2 beta-1,6-N-acetylglucosaminyltransferaseQ48043975
Report on the first international workshop on carcinoma-associated mucinsQ53398836
Delayed mammary tumor progression in Muc-1 null mice.Q53459080
Epitope mapping of anti-breast and anti-ovarian mucin monoclonal antibodiesQ53818020
MUC1 cross-reactive Galα(l,3)Gal antibodies in humans switch immune responses from cellular to humoralQ57594342
The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUMQ58975867
A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomasQ69075433
A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopesQ69103942
Isolation and characterization of mucin-like glycoprotein in human milk fat globule membraneQ70311926
Intramuscular immunisation with MUC1 cDNA can protect C57 mice challenged with MUC1-expressing syngeneic mouse tumour cellsQ70993699
A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinomaQ71153705
P433issue2-3
P407language of work or nameEnglishQ1860
P304page(s)301-313
P577publication date1999-10-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleMUC1 and cancer
P478volume1455

Reverse relations

cites work (P2860)
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Q38307814Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion.
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Q31705505The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.
Q38100999The role of tumour-associated MUC1 in epithelial ovarian cancer metastasis and progression.
Q79298695Tissue and Serum MUC1 Mucin Detection in Breast Cancer Patients
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Q45871048Transfected human dendritic cells to induce antitumor immunity
Q51836026Tumor cell MUC1 and CD43 are glycosylated differently with sialyl-Lewis a and x epitopes and show variable interactions with E-selectin under physiological flow conditions.
Q57006955Tumor-Associated MUC1 Tandem-Repeat Glycopeptide Microarrays to Evaluate Serum- and Monoclonal-Antibody Specificity
Q40656064Tumor-specific glycosylation of the carcinoma-associated epithelial cell adhesion molecule EpCAM in head and neck carcinomas
Q49590854Use of Mass Spectrometry to Screen Glycan Early Markers in Hepatocellular Carcinoma
Q30660122Using in silico transcriptomics to search for tumor-associated antigens for immunotherapy
Q85818776Value of metastin receptor immunohistochemistry in predicting metastasis after radical nephrectomy for pT1 clear cell renal cell carcinoma
Q73943713[Clinical utility of serous tumoural markers]

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