| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.BBRC.2010.02.007 |
| P8608 | Fatcat ID | release_myyydwtywvfftk2bwa3z4okmlm |
| P932 | PMC publication ID | 2853640 |
| P698 | PubMed publication ID | 20138836 |
| P5875 | ResearchGate publication ID | 41413349 |
| P50 | author | Alison Goate | Q45660395 |
| Silva Hecimovic | Q56832004 | ||
| P2093 | author name string | Marko Kosicek | |
| Martina Malnar | |||
| P2860 | cites work | Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes | Q24532064 |
| Cholesterol, lipid rafts, and disease | Q24553188 | ||
| Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts | Q24675729 | ||
| Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa | Q27861105 | ||
| Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease | Q29614374 | ||
| Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells | Q31583322 | ||
| The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo | Q33856244 | ||
| Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts | Q34088442 | ||
| Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein | Q34649008 | ||
| Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons | Q34663462 | ||
| Lipid rafts: heterogeneity on the high seas | Q35602692 | ||
| Cholesterol and the biology of Alzheimer's disease. | Q35625391 | ||
| Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease | Q36797362 | ||
| Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities | Q38722206 | ||
| Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells | Q39738033 | ||
| Mutations in APP have independent effects on Abeta and CTFgamma generation | Q40506128 | ||
| The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1. | Q40631641 | ||
| Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo. | Q42170222 | ||
| Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane. | Q43592684 | ||
| Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains | Q43889089 | ||
| Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. | Q43906981 | ||
| Cholesterol storage and tau pathology in Niemann–Pick type C disease in the brain | Q44401653 | ||
| The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol | Q46502947 | ||
| Testing times for the "amyloid cascade hypothesis". | Q48430429 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | membrane raft | Q424178 |
| P304 | page(s) | 404-409 | |
| P577 | publication date | 2010-02-06 | |
| P1433 | published in | Biochemical and Biophysical Research Communications | Q864228 |
| P1476 | title | Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts | |
| P478 | volume | 393 |
| Q37624954 | Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease |
| Q31088092 | Amyloid-β metabolism in Niemann-Pick C disease models and patients |
| Q38246791 | ApoA-I/HDL Generation and Intracellular Cholesterol Transport through Cytosolic Lipid-Protein Particles in Astrocytes |
| Q89445765 | BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains |
| Q38189670 | Cellular membrane fluidity in amyloid precursor protein processing. |
| Q35700985 | Cholesterol and LDL relate to neuritic plaques and to APOE4 presence but not to neurofibrillary tangles |
| Q42751126 | Cholesterol-dependent energy transfer between fluorescent proteins-insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells. |
| Q35487106 | Defects in the retina of Niemann-pick type C 1 mutant mice |
| Q61809622 | Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein |
| Q88031578 | Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells |
| Q39190496 | Generation of a human neuronal stable cell model for niemann-pick C disease by RNA interference |
| Q42726604 | Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes |
| Q39404682 | Impaired dynamics of the late endosome/lysosome compartment in human Niemann-Pick type C skin fibroblasts carrying mutation in NPC1 gene |
| Q82954776 | Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's |
| Q41604924 | Lipid Rafts: Linking Alzheimer's Amyloid-β Production, Aggregation, and Toxicity at Neuronal Membranes |
| Q33646882 | Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology |
| Q36433310 | Miglustat treatment may reduce cerebrospinal fluid levels of the axonal degeneration marker tau in niemann-pick type C. |
| Q49788408 | N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease model cells. |
| Q41899989 | Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway |
| Q37784257 | Niemann‐Pick type C disease: molecular mechanisms and potential therapeutic approaches |
| Q36590043 | Phospholipids and Alzheimer's disease: alterations, mechanisms and potential biomarkers |
| Q38012858 | Reciprocal regulation of cholesterol and beta amyloid at the subcellular level in Alzheimer's disease |
| Q58586347 | Regimes of Complex Lipid Bilayer Phases Induced by Cholesterol Concentration in MD Simulation |
| Q35650286 | Role of membrane biophysics in Alzheimer's-related cell pathways. |
| Q38090514 | The very many faces of presenilins and the γ-secretase complex. |
| Q36382102 | Upregulated function of mitochondria-associated ER membranes in Alzheimer disease |
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