Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells

scientific article

Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1006289298
P356DOI10.1186/1471-2407-14-432
P932PMC publication ID4065589
P698PubMed publication ID24928086
P5875ResearchGate publication ID263096944

P2093author name stringDagny L Sandnes
Thoralf Christoffersen
Ingun H Tveteraas
John Ødegård
Monica Aasrum
Ingvild J Brusevold
P2860cites workGlobal cancer statisticsQ22241238
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cellsQ24318727
Cell signaling by receptor tyrosine kinasesQ24598357
LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptorQ27310850
Met, metastasis, motility and moreQ28235183
LPA receptors: subtypes and biological actionsQ28269613
Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expressionQ28299091
Microenvironmental regulation of metastasisQ29547660
Seven-transmembrane receptorsQ29619896
Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cellsQ30010057
Activity of 2-Substituted Lysophosphatidic Acid (LPA) Analogs at LPA Receptors: Discovery of a LPA1/LPA3 Receptor AntagonistQ30308302
Role of LPA4/p2y9/GPR23 in negative regulation of cell motilityQ30440331
Structure-function of the G protein-coupled receptor superfamilyQ30576993
Chemotaxis in cancerQ30578627
Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance.Q33753311
Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cellsQ34036069
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascadesQ34225939
Primer-BLAST: A tool to design target-specific primers for polymerase chain reactionQ34307627
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cellsQ35046383
Isoelectric focusing technology quantifies protein signaling in 25 cells.Q35102405
EGFR signal transactivation in cancer cellsQ35594162
Lysophospholipid G protein-coupled receptorsQ35692411
The extracellular matrix in oral squamous cell carcinoma: friend or foe?Q36464327
Epidermal growth factor receptor biology in head and neck cancerQ36500973
Controlling cancer through the autotaxin-lysophosphatidic acid receptor axisQ36664243
Protein kinase C and other diacylglycerol effectors in cancerQ36769838
The role of LPA and YAP signaling in long-term migration of human ovarian cancer cellsQ36847992
Metastasis of squamous cell carcinoma of the oral tongueQ36928038
Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cellsQ37289059
G protein-coupled receptors stimulation and the control of cell migrationQ37403166
Biological roles of lysophosphatidic acid signaling through its production by autotaxinQ37736787
Jekyll and Hyde: the role of the microenvironment on the progression of cancerQ37815128
The molecular biology of head and neck cancerQ37821229
G protein-coupled receptors: novel targets for drug discovery in cancerQ37824814
Autotaxin and LPA receptor signaling in cancerQ37946291
Current progress in non-Edg family LPA receptor researchQ38035634
Lysophosphatidic acid receptor 4 signaling potentially modulates malignant behavior in human head and neck squamous cell carcinoma cellsQ39184225
Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cellsQ39281043
Migration induced by epidermal and hepatocyte growth factors in oral squamous carcinoma cells in vitro: role of MEK/ERK, p38 and PI‐3 kinase/AktQ39380720
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic modelsQ39458550
Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formationQ39702456
Epidermal growth factor increases lysophosphatidic acid production in human ovarian cancer cells: roles for phospholipase D2 and receptor transactivationQ39782375
LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascitesQ39897898
LPA receptor 2 mediates LPA-induced endometrial cancer invasionQ39914739
LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cellsQ40133987
Lysophosphatidic acid down-regulates stress fibers and up-regulates pro-matrix metalloproteinase-2 activation in ovarian cancer cellsQ40168446
Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activityQ40608764
Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid ReceptorsQ40633092
Signal characteristics of G protein-transactivated EGF receptorQ41960343
Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptorQ42049112
Induction of invasion in an organotypic oral cancer model by CoCl2, a hypoxia mimetic.Q42471757
Lysophosphatidic Acid signals through specific lysophosphatidic Acid receptor subtypes to control key regenerative responses of human gingival and periodontal ligament fibroblasts.Q43298340
Lysophosphatidic acid receptor expression and function in human hepatocellular carcinomaQ43653545
Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivationQ44203840
Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytesQ50950996
Secretion of IL-6 and IL-8 from lysophosphatidic acid-stimulated oral squamous cell carcinoma promotes osteoclastogenesis and bone resorption.Q54348437
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectcell migrationQ189092
P304page(s)432
P577publication date2014-06-13
P1433published inBMC CancerQ326300
P1476titleRole of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells
P478volume14

Reverse relations

cites work (P2860)
Q100946289B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation
Q37252696CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer
Q54987153Glycogen synthase kinase-3β mediated regulation of matrix metalloproteinase-9 and its involvement in oral squamous cell carcinoma progression and invasion.
Q92535339Lysophosphatidic acid guides the homing of transplanted olfactory ensheathing cells to the lesion site after spinal cord injury in rats
Q38834081Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells
Q38517084Mechanisms of Invasion in Head and Neck Cancer
Q91758816Mechanisms of PAR-1 mediated kinase receptor transactivation: Smad linker region phosphorylation
Q38933728Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression
Q38817086PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells
Q30400167Phosphorylation and Internalization of Lysophosphatidic Acid Receptors LPA1, LPA2, and LPA3.
Q89172192Role of autotaxin in cancer stem cells
Q26771727Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future Research
Q97544399Tumor immune microenvironment and mutational analysis of tracheal adenoid cystic carcinoma