| scholarly article | Q13442814 |
| P356 | DOI | 10.1128/MCB.20.6.2055-2065.2000 |
| P8608 | Fatcat ID | release_zyqx6dltirgoljw4j7mxsaqyqe |
| P932 | PMC publication ID | 110822 |
| P698 | PubMed publication ID | 10688652 |
| P5875 | ResearchGate publication ID | 12626224 |
| P2093 | author name string | D P Bottaro | |
| T Otsuka | |||
| D Breckenridge | |||
| G Merlino | |||
| J Jakubczak | |||
| W J Larochelle | |||
| W Vieira | |||
| P2860 | cites work | Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product | Q24310794 |
| Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution | Q27766028 | ||
| Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding | Q27766474 | ||
| Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3 | Q28263650 | ||
| Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility | Q28281829 | ||
| A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family | Q28285975 | ||
| Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis | Q28295920 | ||
| Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor | Q28303079 | ||
| Mechanism of met oncogene activation | Q42811433 | ||
| Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients. | Q42828029 | ||
| Functional and biophysical characterization of recombinant human hepatocyte growth factor isoforms produced in Escherichia coli | Q42987814 | ||
| TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas | Q43826975 | ||
| Functional characterization of human hepatocyte growth factor mutants obtained by deletion of structural domains | Q44103436 | ||
| Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas | Q45345804 | ||
| Generation and characterization of a competitive antagonist of human hepatocyte growth factor, HGF/NK1. | Q45998398 | ||
| Switching Signals On or Off by Receptor Dimerization | Q46100759 | ||
| Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation. | Q47789114 | ||
| Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis | Q53426359 | ||
| In Vivo Activation of met Tyrosine Kinase by Heterodimeric Hepatocyte Growth Factor Molecule Promotes Angiogenesis | Q58831780 | ||
| The structures of domains of blood proteins | Q68022183 | ||
| Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas | Q71061803 | ||
| Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity | Q72306296 | ||
| The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit | Q72560868 | ||
| Transforming growth factor alpha disrupts the normal program of cellular differentiation in the gastric mucosa of transgenic mice | Q72572202 | ||
| Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma Invasion | Q74037504 | ||
| HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor | Q74121111 | ||
| Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas | Q77220529 | ||
| c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype | Q77583076 | ||
| Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor | Q28307227 | ||
| Scatter factor/hepatocyte growth factor is essential for liver development | Q28504542 | ||
| Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud | Q28506228 | ||
| Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene | Q33696499 | ||
| A point mutation in the MET oncogene abrogates metastasis without affecting transformation. | Q33731936 | ||
| NK1, a Natural Splice Variant of Hepatocyte Growth Factor/Scatter Factor, Is a Partial Agonist In Vivo | Q33772210 | ||
| Characterization of the rearranged tpr-met oncogene breakpoint | Q34191799 | ||
| Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. | Q34482678 | ||
| Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation | Q35277738 | ||
| Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma | Q35773856 | ||
| Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor | Q35961109 | ||
| The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis | Q36235637 | ||
| Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2. | Q36236835 | ||
| Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network | Q36557528 | ||
| Activating mutations for the Met tyrosine kinase receptor in human cancer | Q36595980 | ||
| Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice | Q36698365 | ||
| Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor | Q36705281 | ||
| Hepatocyte growth factor--scatter factor: mitogen, motogen, and met | Q37105518 | ||
| A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis | Q37329953 | ||
| A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor | Q37370202 | ||
| Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development | Q37559652 | ||
| Identification of a Competitive HGF Antagonist Encoded by an Alternative Transcript | Q38332144 | ||
| Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity | Q38357454 | ||
| Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product | Q40794270 | ||
| Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor | Q40885600 | ||
| Differential signaling by alternative HGF isoforms through c-Met: activation of both MAP kinase and PI 3-kinase pathways is insufficient for mitogenesis | Q40949581 | ||
| Induction of tissue inhibitor of metalloproteinases-3 is a delayed early cellular response to hepatocyte growth factor | Q41018520 | ||
| Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway | Q41024604 | ||
| Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis | Q41038360 | ||
| Agonistic monoclonal antibodies against the Met receptor dissect the biological responses to HGF. | Q41059395 | ||
| Emerging multipotent aspects of hepatocyte growth factor | Q41066829 | ||
| Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K | Q41075804 | ||
| Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET | Q41152225 | ||
| Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers | Q41154099 | ||
| Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells | Q41175020 | ||
| Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis | Q41188806 | ||
| Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase. | Q41270218 | ||
| An alternatively processed mRNA generated from human hepatocyte growth factor gene. | Q41687910 | ||
| HGF/SF in Angiogenesis | Q41730938 | ||
| A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor | Q41879451 | ||
| Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression | Q42389733 | ||
| The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors | Q42473244 | ||
| Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development | Q42770153 | ||
| The Met proto-oncogene mesenchymal to epithelial cell conversion | Q42802751 | ||
| Met expression and sarcoma tumorigenicity | Q42804653 | ||
| Tumorigenesis induced by coexpression of human hepatocyte growth factor and the human met protooncogene leads to high levels of expression of the ligand and receptor | Q42808414 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2055-2065 | |
| P577 | publication date | 2000-03-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis | |
| P478 | volume | 20 |
| Q44249525 | CCl4-induced acute liver injury in mice is inhibited by hepatocyte growth factor overexpression but stimulated by NK2 overexpression |
| Q36558142 | Characterization of an Oncolytic Adenovirus Vector Constructed to Target the cMet Receptor |
| Q35159738 | Design and synthesis of 3,3'-biscoumarin-based c-Met inhibitors |
| Q38847534 | Expression array analysis of the hepatocyte growth factor invasive program |
| Q38019410 | Growth factor signaling in metastasis: current understanding and future opportunities |
| Q49952146 | H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma |
| Q40152004 | HGF ameliorates a high-fat diet-induced fatty liver |
| Q39214964 | HGF–MET Cascade, a Key Target for Inhibiting Cancer Metastasis: The Impact of NK4 Discovery on Cancer Biology and Therapeutics |
| Q50977853 | Hepatocyte Growth Factor Isoforms in Tissue Repair, Cancer, and Fibrotic Remodeling |
| Q38760084 | Hepatocyte growth factor and alternative splice variants - expression, regulation and implications in osteogenesis and bone health and repair |
| Q54448123 | Hepatocyte growth factor pathway upregulation in the bone marrow microenvironment in multiple myeloma is associated with lytic bone disease |
| Q28592355 | Immunohistochemical localization of hepatocyte growth factor activator (HGFA) in developing mouse liver tissues. Heterogeneous distribution of HGFA protein |
| Q43167320 | Inhibitors targeting hepatocyte growth factor receptor and vascular endothelial growth factor receptor tyrosine kinases |
| Q34792580 | Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects |
| Q34103621 | Ligand discrimination by ErbB receptors: differential signaling through differential phosphorylation site usage |
| Q28272688 | MET molecular mechanisms and therapies in lung cancer |
| Q46331197 | Myeloma plasma cell expression of osteoblast regulatory genes: overexpression of SFRP3 correlates with clinical bone involvement at diagnosis |
| Q30484106 | Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39. |
| Q36497156 | Overexpression of NK2 inhibits liver regeneration after partial hepatectomy in mice |
| Q37883394 | Paradoxical action of growth factors: antiproliferative and proapoptotic signaling by HGF/c-MET. |
| Q50985118 | Physiological Signaling and Structure of the HGF Receptor MET. |
| Q28212407 | Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition |
| Q40749632 | SF/HGF-c-Met autocrine and paracrine promote metastasis of hepatocellular carcinoma. |
| Q27663368 | Structural basis for agonism and antagonism of hepatocyte growth factor |
| Q38057539 | Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1 |
| Q37978193 | Targeting MET in cancer: rationale and progress |
| Q36766188 | Targeting the HGF-cMET Axis in Hepatocellular Carcinoma |
| Q44504094 | The N-terminal domain of hepatocyte growth factor inhibits the angiogenic behavior of endothelial cells independently from binding to the c-met receptor |
| Q39736711 | The hepatocyte growth factor isoform NK2 activates motogenesis and survival but not proliferation due to lack of Akt activation |
| Q34588638 | The role of hepatocyte growth factor (scatter factor) in epithelial-mesenchymal transition and breast cancer |
| Q36158717 | Therapeutic targeting of receptor tyrosine kinases in lung cancer |
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