Solution structure of the carbon storage regulator protein CsrA from Escherichia coli

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Solution structure of the carbon storage regulator protein CsrA from Escherichia coli is …
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scholarly articleQ13442814

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P356DOI10.1128/JB.187.10.3496-3501.2005
P932PMC publication ID1112004
P698PubMed publication ID15866937

P50authorKalle GehringQ28037054
P2093author name stringQian Liu
Yan Li
Michael J Osborne
Pablo Gutiérrez
Ekaterina Pomerantseva
P2860cites workIdentification and molecular characterization of csrA, a pleiotropic gene from Escherichia coli that affects glycogen biosynthesis, gluconeogenesis, cell size, and surface propertiesQ24669943
Identification of a global repressor gene, rsmA, of Erwinia carotovora subsp. carotovora that controls extracellular enzymes, N-(3-oxohexanoyl)-L-homoserine lactone, and pathogenicity in soft-rotting Erwinia sppQ24670269
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
Three-dimensional structure and stability of the KH domain: molecular insights into the fragile X syndromeQ27732663
Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrinQ27739804
The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndromeQ27743918
NMRPipe: a multidimensional spectral processing system based on UNIX pipesQ27860859
NMR View: A computer program for the visualization and analysis of NMR dataQ27860951
Protein backbone angle restraints from searching a database for chemical shift and sequence homologyQ27861108
A novel sRNA component of the carbon storage regulatory system of Escherichia coliQ28190971
rsmC of the soft-rotting bacterium Erwinia carotovora subsp. carotovora negatively controls extracellular enzyme and harpin(Ecc) production and virulence by modulating levels of regulatory RNA (rsmB) and RNA-binding protein (RsmA).Q33635870
Novel RNA-binding motif: the KH moduleQ33682738
Global regulatory mutations in csrA and rpoS cause severe central carbon stress in Escherichia coli in the presence of acetateQ33994053
Regulatory interactions of Csr components: the RNA binding protein CsrA activates csrB transcription in Escherichia coliQ34011975
Biofilm formation and dispersal under the influence of the global regulator CsrA of Escherichia coliQ34104887
Pleiotropic regulation of central carbohydrate metabolism in Escherichia coli via the gene csrA.Q34289885
CsrA regulates translation of the Escherichia coli carbon starvation gene, cstA, by blocking ribosome access to the cstA transcriptQ35162003
The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stabilityQ35585353
The global regulator CsrA of Escherichia coli is a specific mRNA-binding proteinQ35626642
Positive regulation of motility and flhDC expression by the RNA-binding protein CsrA of Escherichia coliQ38302059
Regulation of Salmonella enterica serovar typhimurium invasion genes by csrA.Q39517248
A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural informationQ47879770
Direct structure refinement against residual dipolar couplings in the presence of rhombicity of unknown magnitude.Q52243648
CsrA regulates glycogen biosynthesis by preventing translation of glgC in Escherichia coli.Q54543711
Simple techniques for the quantification of protein secondary structure by1H NMR spectroscopyQ57014495
NMR structural studies of human cystatin C dimers and monomersQ57266821
Global regulation by the small RNA-binding protein CsrA and the non-coding RNA molecule CsrBQ77442679
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
solution structureQ99235426
carbon storageQ101953195
P304page(s)3496-3501
P577publication date2005-05-01
P1433published inJournal of BacteriologyQ478419
P1476titleSolution structure of the carbon storage regulator protein CsrA from Escherichia coli
P478volume187

Reverse relations

cites work (P2860)
Q38318114A NMR guided approach for CsrA-RNA crystallization
Q53485212Adaptation of Tri-molecular fluorescence complementation allows assaying of regulatory Csr RNA-protein interactions in bacteria.
Q27679812An unusual CsrA family member operates in series with RsmA to amplify posttranscriptional responses in Pseudomonas aeruginosa
Q27692531Bacterial small RNA regulators: versatile roles and rapidly evolving variations
Q37071165Central role of quorum sensing in regulating the production of pathogenicity factors in Pseudomonas aeruginosa.
Q41452649Comprehensive alanine-scanning mutagenesis of Escherichia coli CsrA defines two subdomains of critical functional importance
Q52309471CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli.
Q35108433CsrA impacts survival of Yersinia enterocolitica by affecting a myriad of physiological activities
Q53568863CsrA of Bacillus subtilis regulates translation initiation of the gene encoding the flagellin protein (hag) by blocking ribosome binding.
Q36038055Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.
Q37258580FliW antagonizes CsrA RNA binding by a noncompetitive allosteric mechanism
Q49791458Functional analyses of the RsmY and RsmZ small non-coding regulatory RNAs in Pseudomonas aeruginosa
Q88541775Genome-wide mapping of the RNA targets of the Pseudomonas aeruginosa riboregulatory protein RsmN
Q55112803Global Regulation by CsrA and Its RNA Antagonists.
Q36224652Hierarchical Post-transcriptional Regulation of Colicin E2 Expression in Escherichia coli
Q36287119Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in Escherichia coli
Q42631303Mechanism of hcnA mRNA recognition in the Gac/Rsm signal transduction pathway of Pseudomonas fluorescens
Q52345594Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT.
Q27647386Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA
Q37328191Molecular geometry of CsrA (RsmA) binding to RNA and its implications for regulated expression
Q42640036Multi-Omics Reveals that Lead Exposure Disturbs Gut Microbiome Development, Key Metabolites, and Metabolic Pathways.
Q34113865Post-transcriptional global regulation by CsrA in bacteria
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Q33959464Posttranscriptional repression of the cel gene of the ColE7 operon by the RNA-binding protein CsrA of Escherichia coli.
Q36068622Primary and Secondary Sequence Structure Requirements for Recognition and Discrimination of Target RNAs by Pseudomonas aeruginosa RsmA and RsmF.
Q28493042Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA
Q92857533RNA Binding by the Campylobacter jejuni Post-transcriptional Regulator CsrA
Q33953019RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family
Q37088770Rapid and robust signaling in the CsrA cascade via RNA-protein interactions and feedback regulation
Q26852008Regulation of bacterial virulence by Csr (Rsm) systems
Q64273852Robust Stoichiometry of FliW-CsrA Governs Flagellin Homeostasis and Cytoplasmic Organization in Bacillus subtilis
Q26852464Small RNAs, 5' UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence
Q35777620Spontaneous phenotypic suppression of GacA-defective Vibrio fischeri is achieved via mutation of csrA and ihfA.
Q45014260Structural Insight into Inhibition of CsrA-RNA Interaction Revealed by Docking, Molecular Dynamics and Free Energy Calculations
Q27679705Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN
Q30152741Structural basis for the CsrA-dependent modulation of translation initiation by an ancient regulatory protein
Q33245450Structural classification of bacterial response regulators: diversity of output domains and domain combinations
Q37984185The Csr/Rsm system of Yersinia and related pathogens: a post-transcriptional strategy for managing virulence
Q37333343The RNA binding protein CsrA is a pleiotropic regulator of the locus of enterocyte effacement pathogenicity island of enteropathogenic Escherichia coli
Q35105638The post-transcriptional regulator rsmA/csrA activates T3SS by stabilizing the 5' UTR of hrpG, the master regulator of hrp/hrc genes, in Xanthomonas
Q38161763The ribonucleoprotein Csr network
Q90657919Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica
Q35921801Vibrio cholerae CsrA Regulates ToxR Levels in Response to Amino Acids and Is Essential for Virulence

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