Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy

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Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1035070713
P356DOI10.1007/S10549-008-0044-Z
P8608Fatcat IDrelease_fxej2kgr5falleqb4irjvzxeqm
P932PMC publication ID4066453
P698PubMed publication ID18481172

P2093author name stringGokul M Das
Wensheng Liu
Matthew B Podgorsak
Margot M Ip
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Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.Q36710840
Wild-type p53: tumors can't stand it.Q36756803
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomesQ36777326
Radiosensitization by antisense anti-MDM2 mixed-backbone oligonucleotide in in vitro and in vivo human cancer modelsQ38344527
Microarray analysis of p53 target gene expression patterns in the spleen and thymus in response to ionizing radiation.Q38350029
Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosisQ40093792
Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cellsQ40221077
Down-regulation of survivin by ultraviolet C radiation is dependent on p53 and results in G(2)-M arrest in A549 cellsQ40234556
Regulation of survivin by retinoic acid and its role in paclitaxel-mediated cytotoxicity in MCF-7 breast cancer cellsQ40306577
Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its functionQ40318351
p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosisQ40926717
The fate of irradiated tumor cellsQ46772707
Breast-conserving surgery with or without radiotherapy: pooled-analysis for risks of ipsilateral breast tumor recurrence and mortality.Q47252460
mdm2 gene alterations and mdm2 protein expression in breast carcinomasQ60609646
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomasQ72769128
Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiationQ79377407
p21 blocks irradiation-induced apoptosis downstream of mitochondria by inhibition of cyclin-dependent kinase-mediated caspase-9 activationQ79405060
Radiation therapy for invasive breast cancer: not just for local controlQ81498277
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectadaptive radiation therapyQ180507
P304page(s)43-50
P577publication date2008-05-15
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleDisruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy
P478volume115

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cites work (P2860)
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Q37046414ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function
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