scholarly article | Q13442814 |
P50 | author | David A Barbie | Q106943892 |
P2093 | author name string | B K Kennedy | |
E Harlow | |||
J A Fletcher | |||
A G Matera | |||
J Zhao | |||
B D Lawrence | |||
P2860 | cites work | PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis | Q22008655 |
Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest | Q22008677 | ||
Structure and Function in the Nucleus | Q22065563 | ||
Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins | Q22253968 | ||
Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription | Q24290273 | ||
Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins | Q24307868 | ||
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals | Q24314293 | ||
The human histone gene cluster at the D6S105 locus | Q24322592 | ||
BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site | Q24554478 | ||
Stem-loop binding protein facilitates 3'-end formation by stabilizing U7 snRNP binding to histone pre-mRNA | Q24554504 | ||
Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors | Q24555701 | ||
Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells | Q24563398 | ||
Structure and in vitro transcription of a human H4 histone gene | Q24604124 | ||
Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry | Q24607291 | ||
H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation | Q24607656 | ||
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition | Q24652527 | ||
Cyclin-dependent kinase control of centrosome duplication | Q24673544 | ||
Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin | Q24680842 | ||
Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies | Q28140953 | ||
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1 | Q28145116 | ||
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle | Q28189224 | ||
Rb interacts with histone deacetylase to repress transcription | Q28263985 | ||
Single-copy flanking sequences in human histone gene clusters map to chromosomes 1 and 6 | Q28290494 | ||
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 | Q28505037 | ||
Formation of the 3' end of histone mRNA | Q28610112 | ||
Distinct roles for cyclin-dependent kinases in cell cycle control | Q29616480 | ||
Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome | Q29618064 | ||
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins | Q29618320 | ||
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation | Q29618497 | ||
Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus | Q29620277 | ||
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein | Q29620737 | ||
Nuclear bodies: multifaceted subdomains of the interchromatin space. | Q33688028 | ||
Association between the nucleolus and the coiled body | Q34140980 | ||
Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts | Q34491024 | ||
Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription | Q35236320 | ||
The cytoplasmic synthesis of histones in hela cells and its temporal relationship to DNA replication | Q35968802 | ||
Chromosome-specific alpha satellite DNA: nucleotide sequence analysis of the 2.0 kilobasepair repeat from the human X chromosome | Q36139991 | ||
Regulation of histone gene expression | Q36183700 | ||
Microinjection of anti-coilin antibodies affects the structure of coiled bodies | Q36255640 | ||
Histone 3' ends: essential and regulatory functions | Q36333814 | ||
Early events in DNA replication require cyclin E and are blocked by p21CIP1 | Q36382696 | ||
The E2F transcription factor activates a replication-dependent human H2A gene in early S phase of the cell cycle | Q36558850 | ||
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest | Q36569398 | ||
An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription | Q36765388 | ||
U1 and U2 small nuclear RNAs are present in nuclear speckles | Q36770130 | ||
Overlapping and CpG methylation-sensitive protein-DNA interactions at the histone H4 transcriptional cell cycle domain: distinctions between two human H4 gene promoters. | Q36819683 | ||
Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene | Q36897138 | ||
RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences | Q36926084 | ||
Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts | Q37256512 | ||
CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F | Q37256817 | ||
The regulation of histone synthesis in the cell cycle | Q37285335 | ||
Quantitative and qualitative changes in histone gene expression during early mouse embryo development | Q37529725 | ||
The regulation of histone gene expression during the cell cycle | Q37691722 | ||
Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity | Q38331736 | ||
Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2. | Q38345991 | ||
Accumulation of E2F-4.DP-1 DNA binding complexes correlates with induction of dhfr gene expression during the G1 to S phase transition | Q39457727 | ||
Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells | Q39575492 | ||
Identification of AP-2 as an interactive target of Rb and a regulator of the G1/S control element of the hamster histone H3.2 promoter. | Q39725498 | ||
Identification of promoter elements necessary for transcriptional regulation of a human histone H4 gene in vitro | Q40665751 | ||
Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator | Q41133317 | ||
Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2. | Q41293458 | ||
p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. | Q41325340 | ||
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system | Q41483751 | ||
The cdk2 kinase is required for the G1-to-S transition in mammalian cells. | Q41548648 | ||
Cyclin-dependent regulation of G1 in mammalian fibroblasts. | Q41565162 | ||
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes | Q41894756 | ||
Cyclin E-CDK2 is a regulator of p27Kip1. | Q42800258 | ||
Regulation of the Mouse Histone H2A.X Gene Promoter by the Transcription Factor E2F and CCAAT Binding Protein | Q42825245 | ||
Developmental regulation of chromatin composition during mouse embryogenesis: somatic histone H1 is first detectable at the 4-cell stage | Q43685996 | ||
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene | Q45283630 | ||
Changes in histone synthesis and modification at the beginning of mouse development correlate with the establishment of chromatin mediated repression of transcription. | Q48958554 | ||
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes. | Q54048106 | ||
Cell-cycle regulatory sequences in a hamster histone promoter and their interactions with cellular factors | Q58973696 | ||
Association of human cyclin E with a periodic G1-S phase protein kinase | Q67505073 | ||
Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro | Q69440258 | ||
Cell-cycle regulation of histone gene expression | Q69509244 | ||
Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element | Q70383880 | ||
Immunological analysis of chromatin: FIS and CHIPS | Q77724511 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2283-97 | |
P577 | publication date | 2000-09-15 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription | |
P478 | volume | 14 |
Q37249372 | A complex barcode underlies the heterogeneous response of p53 to stress |
Q40612662 | A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells |
Q34634110 | A conserved interaction that is essential for the biogenesis of histone locus bodies |
Q24538802 | A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy |
Q40711394 | A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functions |
Q37076659 | A novel single cell method to identify the genetic composition at a single nuclear body |
Q34083319 | A role for the cell cycle phosphatase Cdc25a in vitamin D-dependent inhibition of adult rat vascular smooth muscle cell proliferation |
Q36733668 | A sequence in the Drosophila H3-H4 Promoter triggers histone locus body assembly and biosynthesis of replication-coupled histone mRNAs |
Q28596144 | A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues |
Q36678322 | A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis |
Q42806424 | ATM is a target for positive regulation by E2F-1. |
Q80825988 | Abnormal indices of cell cycle activity in schizophrenia and their potential association with oligodendrocytes |
Q35027641 | Acetylation in hormone signaling and the cell cycle |
Q39682915 | Alternative fates of keratinocytes transduced by human papillomavirus type 18 E7 during squamous differentiation |
Q37970290 | An integrated view of cyclin E function and regulation |
Q54738045 | Analysing differential gene expression in cancer. |
Q27026310 | Another fork in the road--life or death decisions by the tumour suppressor p53 |
Q34587636 | Antiprogestins in gynecological diseases |
Q34395580 | Apoptosis regulators and their role in tumorigenesis |
Q24801392 | Applications of microarray technology in breast cancer research |
Q58088048 | Are p53 inhibitors potentially useful therapeutics? |
Q28116284 | Arginine methylation regulates the p53 response |
Q34570100 | Assessing TP53 status in human tumours to evaluate clinical outcome |
Q36178189 | Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3. |
Q39430447 | Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53 |
Q60938025 | Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs |
Q28507634 | Bax and Bak independently promote cytochrome C release from mitochondria |
Q34313742 | Biogenesis of Nuclear Bodies |
Q47863733 | Birth and Death of Histone mRNAs |
Q33971271 | CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes |
Q24322065 | CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P |
Q94522114 | CDK11 is required for transcription of replication-dependent histone genes |
Q40415938 | CDK2 translational down-regulation during endothelial senescence |
Q24308686 | CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells |
Q38050096 | Cajal bodies: where form meets function |
Q34580489 | Cancer chemoresistance: the relationship between p53 and multidrug transporters |
Q24300976 | Cdc2: a monopotent or pluripotent CDK? |
Q28611368 | Cdk2 dethroned as master of S phase entry |
Q35565486 | Cell cycle control, DNA damage checkpoints and cancer. |
Q34314464 | Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation |
Q24290273 | Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription |
Q24540240 | Cell cycle-regulated trafficking of human telomerase to telomeres |
Q57778801 | Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73 |
Q40835991 | Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization. |
Q54980948 | Cholera toxin-induced modulation of gene expression: elucidation via cDNA microarray for rational cell-based sensor design |
Q47101756 | Chromatin organization changes during the establishment and maintenance of the postmitotic state. |
Q40163392 | Clonal selection for transcriptionally active viral oncogenes during progression to cancer. |
Q36976457 | Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis. |
Q52571236 | Constitutive expression exposes functional redundancy between the Arabidopsis histone H2A gene HTA1 and other H2A gene family members. |
Q33918547 | Control of DNA replication by cyclin-dependent kinases in development |
Q37718853 | Control of cell cycle progression by phosphorylation of cyclin-dependent kinase (CDK) substrates |
Q42005508 | Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase |
Q47110577 | Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body |
Q34153545 | Coupling of DNA synthesis and histone synthesis in S phase independent of cyclin/cdk2 activity |
Q46985048 | Crosstalk between site-specific modifications on p53 and histone H3. |
Q36963933 | Cutaneous vasculitis in breast cancer treated with chemotherapy |
Q35070938 | Cyclin D1 determines mitochondrial function in vivo |
Q34691366 | Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells |
Q28593960 | Cyclin E ablation in the mouse |
Q38909532 | Cyclin E as a potential therapeutic target in high grade serous ovarian cancer |
Q35080261 | Cyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8) and regulates its function in the cell cycle |
Q41874772 | Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells |
Q48823384 | Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice |
Q73727924 | Cycling without CDK2? |
Q36246072 | Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells |
Q40734070 | DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway |
Q44196770 | DNA damage-induced inhibition of securin expression is mediated by p53. |
Q40796673 | DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1. |
Q40799703 | DNA microarrays identification of primary and secondary target genes regulated by p53. |
Q40184751 | DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage |
Q35146582 | Death receptors and melanoma resistance to apoptosis |
Q24309626 | Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression |
Q34068957 | Defying death after DNA damage. |
Q39734889 | Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability |
Q35941628 | Deregulation of the cell cycle by the Epstein-Barr virus |
Q35910908 | Detection of activity centers in cellular pathways using transcript profiling |
Q57808238 | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress |
Q35901909 | Developmental and cell cycle regulation of the Drosophila histone locus body |
Q34276458 | Developmental control of histone mRNA and dSLBP synthesis during Drosophila embryogenesis and the role of dSLBP in histone mRNA 3' end processing in vivo |
Q38363626 | Differential activation of p53 by the various adducts of mitomycin C. |
Q33938034 | Differential control of transcription by DNA-bound cyclins |
Q40008977 | Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7. |
Q38291801 | Direct repression of the Mcl-1 promoter by E2F1. |
Q45345449 | Direct transcriptional activation of human caspase-1 by tumor suppressor p53. |
Q34618921 | Disparate chromatin landscapes and kinetics of inactivation impact differential regulation of p53 target genes |
Q33789802 | Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy |
Q47701598 | Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation |
Q30638825 | Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body. |
Q34736706 | Does p53 affect organismal aging? |
Q35196079 | Drosophila histone locus bodies form by hierarchical recruitment of components |
Q33726575 | Drosophila octamer elements and Pdm-1 dictate the coordinated transcription of core histone genes |
Q35076429 | Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression |
Q48315207 | Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division. |
Q36277309 | Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. |
Q47988949 | Evaluation of techniques using amplified nucleic acid probes for gene expression profiling |
Q39774248 | FLASH degradation in response to UV-C results in histone locus bodies disruption and cell-cycle arrest. |
Q24669918 | FLASH is an essential component of Cajal bodies |
Q24310627 | FLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcription |
Q24669882 | FLASH is required for histone transcription and S-phase progression |
Q34200227 | FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short |
Q42196795 | FLASH, a proapoptotic protein involved in activation of caspase-8, is essential for 3' end processing of histone pre-mRNAs |
Q35739332 | FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors |
Q33899830 | Fidelity of histone gene regulation is obligatory for genome replication and stability |
Q59666805 | Foreman in the histone factory |
Q28751417 | Formation of the 3' end of histone mRNA: getting closer to the end |
Q38274925 | Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. |
Q33265626 | Gene expression patterns associated with p53 status in breast cancer. |
Q38346813 | Gene expression profile linked to p53 status in hepatitis C virus-related hepatocellular carcinoma |
Q25255387 | Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers |
Q34011646 | Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice |
Q38727153 | Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. |
Q35947321 | Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2. |
Q34119242 | Guardian ancestry: fly p53 and damage-inducible apoptosis |
Q34293504 | H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes |
Q24551005 | HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression |
Q40755915 | Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants |
Q24306377 | HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. |
Q24336137 | HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription |
Q33755066 | High Concentration of Melatonin Regulates Leaf Development by Suppressing Cell Proliferation and Endoreduplication in Arabidopsis. |
Q40341382 | High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity. |
Q43690426 | High thermostability and lack of cooperative DNA binding distinguish the p63 core domain from the homologous tumor suppressor p53. |
Q88622704 | Higher order genomic organization and regulatory compartmentalization for cell cycle control at the G1/S-phase transition |
Q46444370 | Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status |
Q40499080 | Histone locus regulation by the Drosophila dosage compensation adaptor protein CLAMP. |
Q35021205 | Histone mRNA expression: multiple levels of cell cycle regulation and important developmental consequences |
Q58876653 | Histone supply: Multitiered regulation ensures chromatin dynamics throughout the cell cycle |
Q39997408 | How p53 wields the scales of fate: arrest or death? |
Q38359785 | How the cell cycle impacts chromatin architecture and influences cell fate |
Q38755170 | Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells |
Q40018422 | Human T Lymphotropic Virus Type 1 protein Tax reduces histone levels |
Q41955139 | Human replication-dependent histone H3 genes are activated by a tandemly arranged pair of two CCAAT boxes |
Q38310551 | Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis |
Q35192615 | Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis |
Q35599241 | ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53 |
Q39285924 | IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes |
Q31046841 | Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo |
Q24317434 | Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17 |
Q24298729 | Identification of HiNF-P, a Key Activator of Cell Cycle-Controlled Histone H4 Genes at the Onset of S Phase |
Q33219594 | Identification of differentially expressed genes in leaf and root between wheat hybrid and its parental inbreds using PCR-based cDNA subtraction |
Q38363282 | Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses. |
Q29619131 | Identification of genes periodically expressed in the human cell cycle and their expression in tumors |
Q33856292 | Identification of proteomic signatures of mantle cell lymphoma, small lymphocytic lymphoma, and marginal zone lymphoma biopsies by surface enhanced laser desorption/ionization-time of flight mass spectrometry |
Q40755207 | Identification of the osteopontin gene as a direct target of TP53. |
Q38436005 | Identifying Nuclear Matrix-Attached DNA Across the Genome |
Q42810225 | Increased p53 transcription prior to DNA synthesis is regulated through a novel regulatory element within the p53 promoter |
Q43146796 | Induced G1 cell-cycle arrest controls replication-dependent histone mRNA 3' end processing through p21, NPAT and CDK9. |
Q47318324 | Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis. |
Q33655472 | Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux |
Q36173829 | Inhibition of autophagy and tumor growth in colon cancer by miR-502. |
Q35842210 | Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer |
Q39640387 | Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin |
Q36580754 | Integration of the metabolic/redox state, histone gene switching, DNA replication and S-phase progression by moonlighting metabolic enzymes. |
Q39834723 | Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase |
Q36444043 | Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription |
Q40540269 | Intra-S-phase checkpoint activation by direct CDK2 inhibition |
Q42509741 | Intranuclear and higher-order chromatin organization of the major histone gene cluster in breast cancer. |
Q37600691 | Intrinsically disordered proteins and their environment: effects of strong denaturants, temperature, pH, counter ions, membranes, binding partners, osmolytes, and macromolecular crowding |
Q40570035 | Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. |
Q35962753 | Lineage-specific and ubiquitous biological roles of the mammalian transcription factor LSF |
Q35012861 | Linking cyclins to transcriptional control. |
Q29547663 | Live or let die: the cell's response to p53 |
Q35805466 | Logic of a mammalian metabolic cycle: an oscillated NAD+/NADH redox signaling regulates coordinated histone expression and S-phase progression |
Q38148964 | Long non-coding RNA-guided regulation in organisms |
Q89944477 | Loss of Histone Locus Bodies in the Mature Hemocytes of Larval Lymph Gland Result in Hyperplasia of the Tissue in mxc Mutants of Drosophila |
Q36947098 | Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes |
Q60017682 | Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies |
Q42817889 | Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2. |
Q40718700 | Mapping the Interaction Network of Key Proteins Involved in Histone mRNA Generation: A Hydrogen/Deuterium Exchange Study |
Q48542298 | Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos |
Q34039841 | Mechanisms of regulatory diversity within the p53 transcriptional network |
Q47416965 | Mechanisms of transcriptional regulation by p53. |
Q28297786 | Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail |
Q47095695 | MicroRNA-936 induces cell cycle arrest and inhibits glioma cell proliferation by targeting CKS1. |
Q42518714 | Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis |
Q38319459 | Multilayered chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of histones |
Q28280147 | Multiple independent evolutionary solutions to core histone gene regulation |
Q35132643 | Multiple signaling pathways involving ATM. |
Q28142503 | Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains |
Q40599166 | Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway. |
Q24684949 | NPAT expression is regulated by E2F and is essential for cell cycle progression |
Q31160333 | Nano-dissection and sequencing of DNA at single sub-nuclear structures |
Q47673940 | Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer. |
Q36827351 | Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases |
Q35597613 | Novel cancer therapy by reactivation of the p53 apoptosis pathway. |
Q35003162 | Nuclear bodies: random aggregates of sticky proteins or crucibles of macromolecular assembly? |
Q40581828 | Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit |
Q23912784 | Opposite effect of NF-kB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite |
Q35833994 | Oxidative stress in aging human skin |
Q34188139 | PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression |
Q40616826 | PCAF is a coactivator for p73-mediated transactivation |
Q28202348 | Pathways governing G1/S transition and their response to DNA damage |
Q39701774 | Persistent p21 expression after Nutlin-3a removal is associated with senescence-like arrest in 4N cells |
Q28143506 | Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells |
Q39139826 | Phenotype-independent effects of retroviral transduction in human dental pulp stem cells. |
Q41980143 | Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells |
Q37700947 | Phosphorylation and the Cajal body: modification in search of function |
Q40486142 | Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. |
Q40627267 | Phosphorylations of Cyclin-dependent Kinase 2 Revisited Using Two-dimensional Gel Electrophoresis |
Q34196515 | Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence |
Q27312776 | Poly (ADP-ribose) polymerase 1 is required for protein localization to Cajal body |
Q46760103 | Proteomic Analysis of Endothelin-1 Targets in the Regulation of Cardiomyocyte Proliferation |
Q36187252 | Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo. |
Q35737442 | Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells |
Q47860453 | RCC2 is a novel p53 target in suppressing metastasis |
Q33892360 | Ras activity regulates cyclin E degradation by the Fbw7 pathway. |
Q43771754 | Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis |
Q47127331 | Regulation of DNA replication-coupled histone gene expression. |
Q46736369 | Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network |
Q38131283 | Regulation of histone gene transcription in yeast |
Q28210189 | Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2 |
Q35132631 | Regulation of p53 after different forms of stress and at different cell cycle stages |
Q38363903 | Regulation of prothymosin alpha by estrogen receptor alpha: molecular mechanisms and relevance in estrogen-mediated breast cell growth |
Q29037634 | Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus |
Q38054735 | Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication |
Q35116649 | Renewing the debate over the p53 apoptotic response |
Q33493863 | Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells |
Q34986765 | Replication-dependent histone gene expression is related to Cajal body (CB) association but does not require sustained CB contact |
Q36189243 | Replication-dependent histone genes are actively transcribed in differentiating and aging retinal neurons |
Q34607206 | Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells |
Q36710840 | Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. |
Q39923722 | Restriction of histone gene transcription to S phase by phosphorylation of a chromatin boundary protein. |
Q47662063 | Rho family GTPases cooperate with p53 deletion to promote primary mouse embryonic fibroblast cell invasion |
Q28190509 | S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component |
Q37246437 | Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle |
Q42463699 | Sequential induction of Hsp25 and proliferating cell nuclear antigen in the kidney after burn |
Q33184299 | Serial analysis of gene expression in normal p53 null mammary epithelium. |
Q44448676 | Several regions of p53 are involved in repression of RNA polymerase III transcription |
Q34225107 | Ski/Sno and TGF-beta signaling. |
Q38300297 | Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein |
Q36964278 | Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells |
Q35088876 | Stimulus-dependent dynamics of p53 in single cells |
Q46813197 | Studies on radiation-induced apoptosis in G0 human lymphocytes |
Q28032484 | Surfing the p53 network |
Q39979160 | Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype. |
Q28506655 | Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development |
Q36020398 | Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D(2) concept |
Q43718785 | The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis |
Q24669553 | The Cyclin E/Cdk2 Substrate and Cajal Body Component p220NPATActivates Histone Transcription through a Novel LisH-Like Domain |
Q36867931 | The HIST1 Locus Escapes Reprogramming in Cloned Bovine Embryos. |
Q42705246 | The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing |
Q34560247 | The Trp53 hemizygous mouse in pharmaceutical development: points to consider for pathologists |
Q82363604 | The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytes |
Q38885465 | The Working Modules of Long Noncoding RNAs in Cancer Cells |
Q36886887 | The abbreviated pluripotent cell cycle. |
Q28609122 | The architectural organization of human stem cell cycle regulatory machinery |
Q35157537 | The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer |
Q33752620 | The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discs |
Q35191541 | The complex interactions of p53 with target DNA: we learn as we go. |
Q38027976 | The control of histone gene expression. |
Q24648864 | The cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cells |
Q34487385 | The evolution of diverse biological responses to DNA damage: insights from yeast and p53. |
Q37602507 | The expanding universe of p53 targets |
Q77368785 | The expression of genes induced in melanocytes by exposure to 365-nm UVA: study by cDNA arrays and real-time quantitative RT-PCR |
Q24645732 | The first 30 years of p53: growing ever more complex |
Q28140732 | The function of PML in p53-dependent apoptosis |
Q40851854 | The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression |
Q28588582 | The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles |
Q24321813 | The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif |
Q41142269 | The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT. |
Q28818369 | The histone genes cluster in Rhynchosciara americana and its transcription profile in salivary glands during larval development |
Q41953832 | The osmoregulatory and the amino acid-regulated responses of system A are mediated by different signal transduction pathways. |
Q33757941 | The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors. |
Q43682294 | The periodic down regulation of Cyclin E gene expression from exit of mitosis to end of G(1) is controlled by a deacetylase- and E2F-associated bipartite repressor element |
Q35105986 | The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. |
Q34564813 | The retinoblastoma protein regulates pericentric heterochromatin |
Q34038183 | The role of nuclear bodies in gene expression and disease |
Q35196996 | The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types |
Q40667908 | The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells |
Q34086453 | Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo. |
Q93088610 | Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress |
Q36421122 | Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition |
Q40698245 | Transcriptional activation of the MUC2 gene by p53. |
Q36116613 | Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition |
Q29617650 | Transcriptional control of human p53-regulated genes |
Q36436698 | Transcriptional regulation by p53: one protein, many possibilities |
Q28190792 | Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1 |
Q50335767 | Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. |
Q34286036 | Transcriptomes, transcription activators and microarrays |
Q93229535 | Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1 |
Q24794459 | Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein |
Q44418346 | Transgenic expression of prothymosin alpha on zebrafish epidermal cells promotes proliferation and attenuates UVB-induced apoptosis |
Q40752768 | Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. |
Q40568020 | Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes. |
Q37591937 | Tumour suppression by p53: a role for the DNA damage response? |
Q35889316 | U7 small nuclear ribonucleoprotein represses histone gene transcription in cell cycle-arrested cells. |
Q39745903 | UV-induced fragmentation of Cajal bodies. |
Q35681983 | Validation of a liquid chromatography-triple quadrupole mass spectrometric method for the determination of 5-nitro-5'-hydroxy-indirubin-3'-oxime (AGM-130) in human plasma and its application to microdose clinical trial |
Q36538369 | Versican: signaling to transcriptional control pathways. |
Q34335765 | WEE1 tyrosine kinase, a novel epigenetic modifier |
Q38241194 | When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage |
Q37367277 | Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53. |
Q44720926 | X-irradiated human lymphocytes with unstable aberrations and their preferential elimination by p53/survivin-dependent apoptosis |
Q31060526 | Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication |
Q83790495 | [Technology of analysis of epigenetic and structural changes of epithelial tumors genome with NotI-microarrays by the example of human chromosome] |
Q44208216 | cAMP-dependent reorganization of the Cajal bodies and splicing machinery in cultured Schwann cells |
Q34482630 | miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. |
Q33344707 | microRNAs join the p53 network--another piece in the tumour-suppression puzzle |
Q40647697 | p21/CDKN1A mediates negative regulation of transcription by p53. |
Q33842575 | p21cip1 Degradation in differentiated keratinocytes is abrogated by costabilization with cyclin E induced by human papillomavirus E7. |
Q37832072 | p53 and its mutants in tumor cell migration and invasion |
Q36180705 | p53 checkpoint ablation exacerbates the phenotype of Hinfp dependent histone H4 deficiency |
Q35116655 | p53 downstream targets and chemosensitivity. |
Q34173945 | p53 dynamics control cell fate |
Q36423948 | p53 in recombination and repair |
Q40842648 | p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway |
Q33819326 | p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling |
Q37622549 | p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression |
Q42941221 | p53 regulates myogenesis by triggering the differentiation activity of pRb. |
Q38704009 | p53 responsive elements in human retrotransposons. |
Q40810981 | p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells |
Q36133972 | p53-Regulated Networks of Protein, mRNA, miRNA, and lncRNA Expression Revealed by Integrated Pulsed Stable Isotope Labeling With Amino Acids in Cell Culture (pSILAC) and Next Generation Sequencing (NGS) Analyses |
Q34305233 | p53-dependent apoptosis pathways. |
Q28394092 | p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis |
Q36028209 | p53: traffic cop at the crossroads of DNA repair and recombination |
Q36163707 | p53: twenty five years understanding the mechanism of genome protection |
Q33933714 | p53CP is p51/p63, the third member of the p53 gene family: partial purification and characterization |
Q24307639 | p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1 |
Q39121067 | p53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells |
Q45050263 | string(cdc25) and cyclin E are required for patterned histone expression at different stages of Drosophila embryonic development. |
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