review article | Q7318358 |
scholarly article | Q13442814 |
retracted paper | Q45182324 |
P2093 | author name string | Jae-Yong Koh | |
P2860 | cites work | The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein | Q24336853 |
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice | Q24530682 | ||
MT-III, a brain-specific member of the metallothionein gene family | Q24564603 | ||
Amyloid plaque core protein in Alzheimer disease and Down syndrome | Q24568384 | ||
Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene | Q24671498 | ||
NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR. | Q27876222 | ||
Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy | Q28281986 | ||
Nitric oxide induces Zn2+ release from metallothionein by destroying zinc-sulphur clusters without concomitant formation of S-nitrosothiol | Q28343675 | ||
Zinc inhibition of gamma-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus | Q28372987 | ||
Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator | Q28373854 | ||
Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein | Q28509018 | ||
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors | Q28776368 | ||
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein | Q29547803 | ||
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease | Q29617986 | ||
Brief exposure to zinc is toxic to cortical neurons | Q48275629 | ||
Zn2+ entry produces oxidative neuronal necrosis in cortical cell cultures | Q48284457 | ||
Depletion of intracellular zinc induces protein synthesis-dependent neuronal apoptosis in mouse cortical culture | Q48316130 | ||
Release of zinc sulphide accumulations into synaptic clefts after in vivo injection of sodium sulphide | Q48386390 | ||
Copper, iron and zinc in Alzheimer's disease senile plaques | Q48429285 | ||
Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress | Q48478034 | ||
Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron | Q48491695 | ||
A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation | Q48507478 | ||
Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors. | Q48617420 | ||
Rapid, experience-dependent changes in levels of synaptic zinc in primary somatosensory cortex of the adult mouse. | Q48646256 | ||
Imaging free zinc in synaptic terminals in live hippocampal slices | Q48678200 | ||
Release of endogenous Zn2+ from brain tissue during activity | Q48682530 | ||
Rapid translocation of Zn(2+) from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation | Q48718833 | ||
Cytoarchitectonic distribution of zinc in the hippocampus of man and the rat. | Q48757432 | ||
Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures. | Q48799487 | ||
Neuronal cell death and tPA. | Q48861457 | ||
Changes in newt brain caused by zinc water-pollution | Q48932979 | ||
High-affinity zinc inhibition of NMDA NR1-NR2A receptors | Q48954602 | ||
Comparative toxicity of a zinc salt, zinc powder and zinc oxide to Eisenia fetida, Enchytraeus albidus and Folsomia candida | Q49153457 | ||
Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model | Q49161890 | ||
Modulation of zinc toxicity by tissue plasminogen activator. | Q51037608 | ||
Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation | Q53200632 | ||
Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis. | Q53222718 | ||
Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes. | Q53235461 | ||
Copper catalyzed oxidation of Alzheimer Abeta. | Q53236205 | ||
Rapid induction of Alzheimer A beta amyloid formation by zinc. | Q53316140 | ||
Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. | Q53338399 | ||
Characterization of Copper Interactions with Alzheimer Amyloid β Peptides | Q57080882 | ||
Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress | Q57341985 | ||
The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction† | Q58842885 | ||
Translocation of zinc may contribute to seizure-induced death of neurons | Q69597365 | ||
The role of zinc in selective neuronal death after transient global cerebral ischemia | Q71095999 | ||
Intoxication Following Ingestion of Elemental Zinc | Q71564989 | ||
Metallothionein in amyotrophic lateral sclerosis | Q72449870 | ||
Excitation-transcription coupling mediated by zinc influx through voltage-dependent calcium channels | Q72536299 | ||
Chelation of intracellular zinc triggers apoptosis in mature thymocytes | Q72832726 | ||
Zn2+ current is mediated by voltage-gated Ca2+ channels and enhanced by extracellular acidity in mouse cortical neurones | Q73038613 | ||
Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia | Q73146102 | ||
Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes | Q73221688 | ||
Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat | Q73315743 | ||
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase | Q73316561 | ||
Routes of zinc entry in mouse cortical neurons: role in zinc-induced neurotoxicity | Q73395620 | ||
Evidence that synaptically-released zinc contributes to neuronal injury after traumatic brain injury | Q73457837 | ||
Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis | Q73548002 | ||
Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis | Q73704452 | ||
Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner | Q73741280 | ||
Superoxide-dependent peroxidase activity of H48Q: a superoxide dismutase variant associated with familial amyotrophic lateral sclerosis | Q73818063 | ||
[A new method for demonstrating A and B cells in the islands of Langerhans] | Q73907404 | ||
Zinc-induced neuronal death in cortical neurons | Q73942275 | ||
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion | Q77089411 | ||
Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease | Q78021412 | ||
Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins | Q78397249 | ||
Synaptically released zinc: physiological functions and pathological effects. | Q30329555 | ||
Advances in intravenous thrombolytic therapy for treatment of acute stroke | Q30660472 | ||
Zinc biosensing with multiphoton excitation using carbonic anhydrase and improved fluorophores | Q30901192 | ||
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation | Q31154202 | ||
Use of trifluoroperazine isolates a [(3)H]Ifenprodil binding site in rat brain membranes with the pharmacology of the voltage-independent ifenprodil site on N-methyl-D-aspartate receptors containing NR2B subunits. | Q31726338 | ||
Redox-active iron mediates amyloid-beta toxicity | Q31967419 | ||
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes | Q33187996 | ||
Inhibitory sites in enzymes: zinc removal and reactivation by thionein | Q33853678 | ||
Causes of iron and zinc deficiencies and their effects on brain | Q33866112 | ||
The function of zinc metallothionein: a link between cellular zinc and redox state | Q33913061 | ||
Enzyme regulation by reversible zinc inhibition: glycerol phosphate dehydrogenase as an example | Q33942698 | ||
Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity | Q33944240 | ||
Zn(2+): a novel ionic mediator of neural injury in brain disease. | Q34069624 | ||
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. | Q34082498 | ||
Epilepsy-associated plasticity in gamma-aminobutyric acid receptor expression, function, and inhibitory synaptic properties | Q34114345 | ||
Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules | Q34150666 | ||
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial | Q34283745 | ||
Control of zinc transfer between thionein, metallothionein, and zinc proteins | Q34461793 | ||
Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange | Q34931641 | ||
The metallobiology of Alzheimer's disease | Q35104793 | ||
Zinc and excitotoxic brain injury: a new model. | Q35677213 | ||
Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2. | Q36485372 | ||
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion | Q36704795 | ||
Neurobiology of zinc and zinc-containing neurons | Q38740484 | ||
The influence of zinc on apoptosis. | Q40547531 | ||
Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling. | Q40612024 | ||
A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells. | Q40622344 | ||
Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc | Q40881389 | ||
Stimulation-induced uptake and release of zinc in hippocampal slices | Q41595071 | ||
Alterations in physiological parameters of rainbow trout (Oncorhynchus mykiss) with exposure to copper and copper/zinc mixtures | Q41615946 | ||
Glutamate triggers preferential Zn2+ flux through Ca2+ permeable AMPA channels and consequent ROS production. | Q41692737 | ||
Zinc and brain injury | Q41733300 | ||
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits. | Q41843219 | ||
Cleavage of amyloid beta peptide during constitutive processing of its precursor | Q41852594 | ||
Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosis | Q41934794 | ||
Senile dementia of the Alzheimer type | Q42447051 | ||
Accumulation of zinc in degenerating hippocampal neurons of ZnT3-null mice after seizures: evidence against synaptic vesicle origin. | Q43502978 | ||
New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps. | Q43615257 | ||
Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells | Q43694502 | ||
Imaging synaptic zinc release in living nervous tissue. | Q43743079 | ||
Induction of mossy fiber --> Ca3 long-term potentiation requires translocation of synaptically released Zn2+. | Q43757456 | ||
Protection by pyruvate against transient forebrain ischemia in rats. | Q43757489 | ||
Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria. | Q43763070 | ||
Treatment of Alzheimer's disease with clioquinol | Q43764762 | ||
In vivo peroxidative activity of FALS-mutant human CuZnSODs expressed in yeast | Q43857845 | ||
Blockade of Ca2+-permeable AMPA/kainate channels decreases oxygen-glucose deprivation-induced Zn2+ accumulation and neuronal loss in hippocampal pyramidal neurons. | Q43890677 | ||
Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons. | Q44070813 | ||
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). | Q44111677 | ||
Augmentation by zinc of NMDA receptor-mediated synaptic responses in CA1 of rat hippocampal slices: mediation by Src family tyrosine kinases | Q44125206 | ||
Loss of zinc staining from hippocampal mossy fibers during kainic acid induced seizures: a histofluorescence study | Q44143058 | ||
Nitric oxide causes apparent release of zinc from presynaptic boutons | Q44209097 | ||
The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture | Q44214522 | ||
Zinc translocation accelerates infarction after mild transient focal ischemia. | Q44219027 | ||
Depletion of intracellular zinc from neurons by use of an extracellular chelator in vivo and in vitro | Q44251859 | ||
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence | Q44356224 | ||
Labeling of the neurons of origin of zinc-containing pathways by intraperitoneal injections of sodium selenite | Q44410749 | ||
Hippocampal mossy fiber calcium transients are maintained during long-term potentiation and are inhibited by endogenous zinc | Q44504156 | ||
Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death | Q44519078 | ||
Co-induction of p75(NTR) and the associated death executor NADE in degenerating hippocampal neurons after kainate-induced seizures in the rat. | Q44520841 | ||
AMPA/kainate receptor-triggered Zn2+ entry into cortical neurons induces mitochondrial Zn2+ uptake and persistent mitochondrial dysfunction. | Q44521550 | ||
Involvement of poly ADP ribosyl polymerase-1 in acute but not chronic zinc toxicity | Q44597428 | ||
Endogenous zinc inhibits GABA(A) receptors in a hippocampal pathway | Q44619363 | ||
Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury | Q44668518 | ||
Estrogen decreases zinc transporter 3 expression and synaptic vesicle zinc levels in mouse brain | Q44697391 | ||
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta | Q44724513 | ||
Pyruvate limits zinc-induced rat oligodendrocyte progenitor cell death. | Q44729799 | ||
Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure-induced ischemia in vivo | Q44865878 | ||
Characterization of extracellular accumulation of Zn2+ during ischemia and reperfusion of hippocampus slices in rat. | Q44878925 | ||
Zinc release contributes to hypoglycemia-induced neuronal death | Q44985238 | ||
The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice | Q45090946 | ||
GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat. | Q45113967 | ||
Zinc selectively blocks the action of N-methyl-D-aspartate on cortical neurons | Q45194545 | ||
Kainate-stimulated Zn2+ uptake labels cortical neurons with Ca2+-permeable AMPA/kainate channels | Q46723092 | ||
Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome | Q46751023 | ||
Modulation of GABA-mediated synaptic transmission by endogenous zinc in the immature rat hippocampus in vitro | Q48097244 | ||
Modulation of A beta adhesiveness and secretase site cleavage by zinc. | Q48138461 | ||
Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion | Q48142442 | ||
Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons | Q48220506 | ||
Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures | Q48251152 | ||
Zinc-induced cortical neuronal death with features of apoptosis and necrosis: mediation by free radicals | Q48273533 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P304 | page(s) | 121-133 | |
P577 | publication date | 2005-10-20 | |
P1433 | published in | Journal of clinical neurology | Q26841853 |
P1476 | title | Endogenous zinc in neurological diseases | |
P478 | volume | 1 |