Differential gene expression in glaucoma

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Differential gene expression in glaucoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1101/CSHPERSPECT.A020636
P932PMC publication ID4066643
P698PubMed publication ID24985133
P5875ResearchGate publication ID263742799

P50authorTatjana C JakobsQ55590620
P2093author name stringTatjana C Jakobs
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Global gene expression changes in rat retinal ganglion cells in experimental glaucomaQ30495710
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Early microglia activation in a mouse model of chronic glaucomaQ30587345
Differential gene expression in the human ciliary epitheliumQ30668378
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Extracellular matrix changes of the optic nerve lamina cribrosa in monkey eyes with experimentally chronic glaucomaQ33204219
Genes expressed in the human trabecular meshwork during pressure-induced homeostatic responseQ33205289
Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-betaQ33208285
Expression of phosphorylated c-Jun N-terminal protein kinase (JNK) in experimental glaucoma in ratsQ33224379
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Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetricQ33259237
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Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in ratsQ73006494
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Plasma and aqueous humor endothelin levels in primary open-angle glaucomaQ73213641
Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cellsQ73258549
Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucomaQ73535458
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Enhanced tenascin expression associated with reactive astrocytes in human optic nerve heads with primary open angle glaucomaQ78162612
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Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposureQ82845420
GlaucomaQ83757307
Endothelin-1 impairs retrograde axonal transport and leads to axonal injury in rat optic nerveQ83831103
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Alterations in elastin of the optic nerve head in human and experimental glaucomaQ33649055
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Retinal Ganglion Cell Loss in a Rat Ocular Hypertension Model Is Sectorial and Involves Early Optic Nerve Axon LossQ33681832
Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucomaQ33693579
Structural remodeling of fibrous astrocytes after axonal injury.Q33723779
Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma ModelQ33738662
Gene expression changes in areas of focal loss of retinal ganglion cells in the retina of DBA/2J miceQ33845093
Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic miceQ33867506
The optic nerve head in glaucoma: role of astrocytes in tissue remodelingQ33882462
High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucomaQ33934185
The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse.Q33975340
Morphologic changes in the outflow pathways of bovine eyes treated with corticosteroidsQ34022583
Astrocytic responses in the lateral geniculate nucleus of monkeys with experimental glaucomaQ34066277
Apoptosis in adult retinal ganglion cells after axotomyQ34333280
Etanercept, a widely used inhibitor of tumor necrosis factor-α (TNF-α), prevents retinal ganglion cell loss in a rat model of glaucomaQ34339649
Early reduction of microglia activation by irradiation in a model of chronic glaucomaQ34405368
Gene expression and functional annotation of the human ciliary body epithelia.Q34427792
Reactive astrocytes in neural repair and protectionQ34449475
Cell Proliferation and Interleukin-6–Type Cytokine Signaling Are Implicated by Gene Expression Responses in Early Optic Nerve Head Injury in Rat GlaucomaQ34646791
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucomaQ34755301
A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucomaQ35082369
Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshworkQ35591485
Glaucomatous optic neuropathy: when glia misbehaveQ35609009
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucomaQ35858120
Retinal gene expression changes related to IOP exposure and axonal loss in DBA/2J miceQ35908952
Detection of differentially expressed glycogenes in trabecular meshwork of eyes with primary open-angle glaucomaQ35925346
Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma modelQ35945481
Periostin family of proteins: therapeutic targets for heart diseaseQ36293104
Genomic analysis of reactive astrogliosisQ36344611
'What controls aqueous humour outflow resistance?'.Q36357303
Morphology of astrocytes in a glaucomatous optic nerveQ36587662
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucomaQ36639100
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell deathQ36673015
Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crushQ36717830
Regulation of SPARC by transforming growth factor β2 in human trabecular meshworkQ36765850
Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene productQ36864380
Exon-level expression profiling of ocular tissuesQ36875675
Open-angle glaucoma -- an epidemiologic overviewQ36951789
Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cellsQ37054969
Reversible reactivity by optic nerve astrocytesQ37146426
Preconditioning-induced protection from oxidative injury is mediated by leukemia inhibitory factor receptor (LIFR) and its ligands in the retinaQ37195035
Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucomaQ37208897
Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspectsQ37329052
Structural changes of the trabecular meshwork in different kinds of glaucomaQ37359647
The trabecular meshwork outflow pathways: structural and functional aspects.Q37400335
The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visitedQ37644606
Mechanisms of retinal ganglion cell injury and defense in glaucomaQ37731595
What has gene expression profiling taught us about glaucoma?Q37800208
Dendritic changes in visual pathways in glaucoma and other neurodegenerative conditions.Q37839287
Lipocalin 2 regulation and its complex role in inflammation and cancerQ37920158
Retina ganglion cell degeneration in glaucoma: an opportunity missed? A reviewQ37992209
Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathyQ38004641
cDNA microarray analysis of gene expression changes induced by dexamethasone in cultured human trabecular meshwork cellsQ38360457
Expression profiling in glaucomatous human lamina cribrosa cells based on graph-clustering approachQ38491589
Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegenerationQ39132026
Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucomaQ40674190
Glaucoma: changes in extracellular matrix in the optic nerve headQ40769903
The major cell populations of the mouse retina.Q40838448
The optic nerve head in glaucomatous optic neuropathyQ41390007
Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucomaQ41411098
Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.Q42126987
Astrocytes in glaucomatous optic neuropathyQ42600591
Transforming growth factor beta 2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb developmentQ42652061
Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J miceQ42665432
Collagen type IV gene expression in human optic nerve heads with primary open angle glaucomaQ42688866
Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J miceQ42914157
Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factorQ43244105
Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion.Q43607601
Neurotrophin and neurotrophin receptor expression by cells of the human lamina cribrosaQ43723400
Optic nerve head extracellular matrix in primary optic atrophy and experimental glaucomaQ44319403
Differential Temporal and Spatial Expression of Immediate Early Genes in Retinal Neurons after Ischemia–Reperfusion InjuryQ44417324
Quantitative study of collagen and elastin of the optic nerve head and sclera in human and experimental monkey glaucomaQ44545194
Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 miceQ44669093
Evaluation of inducible nitric oxide synthase in glaucomatous optic neuropathy and pressure-induced optic nerve damageQ46404445
Essential protective roles of reactive astrocytes in traumatic brain injuryQ46428573
Gene expression changes in the retina following optic nerve transection.Q46588535
Inhibition and recovery of retrograde axoplasmic transport in rat optic nerve during and after elevated IOP in vivoQ46655285
Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucomaQ46667386
Acute endothelin-1 application induces reversible fast axonal transport blockade in adult rat optic nerveQ46713858
Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cellsQ46769376
Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cellsQ46930398
Microarray analysis of retinal gene expression in the DBA/2J model of glaucomaQ46966279
Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressureQ47903438
Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.Q48093574
Chronic ocular hypertension induces dendrite pathology in the lateral geniculate nucleus of the brainQ48374903
Minocycline delays death of retinal ganglion cells in experimental glaucoma and after optic nerve transectionQ48587751
Impaired neuroglial activation in interleukin-6 deficient miceQ48789897
Concentration of astrocytic filaments at the retinal optic nerve junction is coincident with the absence of intra-retinal myelination: comparative and developmental evidence.Q48880448
Cultured astrocytes react to LPS with increased cyclooxygenase activity and phagocytosisQ48974146
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.Q50726567
Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure.Q51575878
Experimental glaucoma and optic nerve transection induce simultaneous upregulation of proapoptotic and prosurvival genes.Q53621184
Transforming growth factor-beta 2 levels in aqueous humor of glaucomatous eyes.Q53891879
Matrix metalloproteinases and tumor necrosis factor alpha in glaucomatous optic nerve head.Q53911833
Endothelin-like immunoreactivity in aqueous humor of patients with primary open-angle glaucoma and cataract.Q53963733
Ultrastructural immunocytochemical analysis of elastin in the human lamina cribrosa. Changes in elastic fibers in primary open-angle glaucoma.Q54059947
Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure.Q54571625
Cell culture of the human lamina cribrosaQ68123354
Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyesQ70944559
The fine structure of the cribriform meshwork in normal and glaucomatous eyes as seen in tangential sectionsQ70944562
Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damageQ71466504
Programmed cell death of retinal ganglion cells during experimental glaucomaQ71735807
Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosisQ72131673
Structure and composition of the rodent lamina cribrosaQ72314369
Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transportQ72604001
Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damageQ72633267
P433issue7
P304page(s)a020636
P577publication date2014-07-01
P1433published inCold Spring Harbor Perspectives in MedicineQ21042440
P1476titleDifferential gene expression in glaucoma
P478volume4

Reverse relations

cites work (P2860)
Q90386421A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma
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Q36384654MicroRNA Expression in the Glaucomatous Retina
Q35558052Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma
Q36236822Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration
Q36298531Whole exome sequencing implicates eye development, the unfolded protein response and plasma membrane homeostasis in primary open-angle glaucoma.

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