An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells

scientific article

An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2010.287
P932PMC publication ID3070092
P698PubMed publication ID21224831
P5875ResearchGate publication ID49745661

P2093author name stringDavid V Schaffer
James T Koerber
Inchan Kwon
Jae-Hyung Jang
Tandis Vazin
Kook In Park
Prashanth Asuri
Jung-Suk Kim
Melissa Bartel
Albert Keung
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Gene targeting in stem cells from individuals with osteogenesis imperfectaQ24310539
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Highly efficient endogenous human gene correction using designed zinc-finger nucleasesQ28243157
Rapid evolution of a protein in vitro by DNA shufflingQ28245873
Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transferQ28271767
Promotion of reprogramming to ground state pluripotency by signal inhibitionQ28473911
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivoQ28572747
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectorsQ29547596
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectorsQ30975099
In vitro selection of viral vectors with modified tropism: the adeno-associated virus displayQ33187644
Directed evolution of adeno-associated virus yields enhanced gene delivery vectorsQ33232270
Selection of novel vesicular stomatitis virus glycoprotein variants from a peptide insertion library for enhanced purification of retroviral and lentiviral vectorsQ33236504
Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transferQ33315634
DNA shuffling of adeno-associated virus yields functionally diverse viral progenyQ33363531
Molecular evolution of adeno-associated virus for enhanced glial gene deliveryQ33492733
Two factor reprogramming of human neural stem cells into pluripotencyQ33504579
Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration propertiesQ33628417
Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblastsQ33796712
Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS.Q33874690
The development of neural stem cellsQ34100159
PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiationQ34653250
Oct4-induced pluripotency in adult neural stem cells.Q34940495
Progress and problems with the use of viral vectors for gene therapyQ35120176
Gene targeting with viral vectorsQ36149196
Gene therapy: twenty-first century medicineQ36161193
Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virusQ36242842
Progress and prospects: gene transfer into embryonic stem cellsQ36611026
Optimization of DNA shuffling for high fidelity recombinationQ36852677
Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectorsQ36893512
Non-viral gene transfection technologies for genetic engineering of stem cellsQ36942833
Genetically engineered stem cells for therapeutic gene deliveryQ36985452
Development of a novel mouse glioma model using lentiviral vectorsQ37164106
Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan bindingQ39756934
Direct reprogramming of human neural stem cells by OCT4.Q39806256
HIV evades RNA interference directed at TAR by an indirect compensatory mechanism.Q39919699
Construction of diverse adeno-associated viral libraries for directed evolution of enhanced gene delivery vehiclesQ40150114
Stable genetic modification of human embryonic stem cells by lentiviral vectorsQ40669101
Transfer of high copy number plasmid into mammalian cells by calcium phosphate transfectionQ40798953
Human gene targeting by viral vectorsQ41480639
Nonviral gene delivery to mesenchymal stem cells using cationic liposomes for gene and cell therapyQ41855899
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Viral-mediated gene transfer to mouse primary neural progenitor cells.Q45882544
Rapid generation of knockdown transgenic mice by silencing lentiviral vectorsQ46497192
Infection Efficiency of Human and Mouse Embryonic Stem Cells Using Adenoviral and Adeno-Associated Viral VectorsQ47953700
Human neurospheres derived from the fetal central nervous system are regionally and temporally specified but are not committedQ48530443
Transient disruption of autocrine TGF-beta signaling leads to enhanced survival and proliferation potential in single primitive human hemopoietic progenitor cells.Q52544934
P433issue4
P921main subjectgene targetingQ211083
neural stem cellQ2944097
P304page(s)667-675
P577publication date2011-01-11
P1433published inMolecular TherapyQ15762400
P1476titleAn evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells
P478volume19

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