T cell receptor V genes in multiple sclerosis: increased use of TCRAV8 and TCRBV5 in MBP-specific clones

scientific article

T cell receptor V genes in multiple sclerosis: increased use of TCRAV8 and TCRBV5 in MBP-specific clones is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3109/08830189909043017
P698PubMed publication ID10614737

P2093author name stringOffner H
Vandenbark AA
P2860cites workT cells responsive to myelin basic protein in patients with multiple sclerosisQ45150262
Evidence for a differential avidity model of T cell selection in the thymusQ45155438
The expressed T cell receptor V gene repertoire of rheumatoid arthritis monozygotic twins: rapid analysis by anchored polymerase chain reaction and enzyme-linked immunosorbent assay.Q46036058
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TCR peptide therapy decreases the frequency of encephalitogenic T cells in the periphery and the central nervous systemQ46747908
Characterization of the human T cell receptor alpha-chain repertoire and demonstration of a genetic influence on V alpha usageQ48121902
Double-Blind Pilot Trial of Oral Tolerization with Myelin Antigens in Multiple SclerosisQ50127386
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Multiple sclerosis and the HLA-D region: linkage and association studiesQ58133059
An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complexQ27733448
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The specificity and orientation of a TCR to its peptide-MHC class II ligandsQ28592120
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Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patientsQ33890993
Structure of human T-cell receptors specific for an immunodominant myelin basic protein peptide: positioning of T-cell receptors on HLA-DR2/peptide complexesQ33935942
Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupusQ34199681
A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosisQ36229747
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoireQ36230696
Preferential V beta gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility coQ36231048
T cell receptor V alpha-V beta repertoire and cytokine gene expression in active multiple sclerosis lesionsQ36231183
In a small multideterminant peptide, each determinant is recognized by a different V beta gene segmentQ36231548
Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosisQ36362874
In vivo clonal dominance and limited T-cell receptor usage in human CD4+ T-cell recognition of house dust mite allergensQ36517424
Expansion of a recurrent V beta 5.3+ T-cell population in newly diagnosed and untreated HLA-DR2 multiple sclerosis patientsQ37241657
Preferential T-cell receptor beta-chain variable gene use in myelin basic protein-reactive T-cell clones from patients with multiple sclerosisQ37607593
Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenicsQ38330987
Immunologic Mechanisms and Therapy in Multiple SclerosisQ40433260
T cell receptor peptides in treatment of autoimmune disease: rationale and potentialQ41027832
Frequency of T cells specific for myelin basic protein and myelin proteolipid protein in blood and cerebrospinal fluid in multiple sclerosisQ41092306
T-cell receptor variable β genes show differential expression in CD4 and CD8 T cellsQ41135810
TCR usage in human and experimental demyelinating diseaseQ41166688
MHC-Restricted Depletion of Human Myelin Basic Protein-Reactive T Cells by T Cell VaccinationQ41528229
Predictable acquisition of a new MHC recognition specificity following expression of a transfected T-cell receptor beta-chain geneQ42074725
Shared human T cell receptor V beta usage to immunodominant regions of myelin basic proteinQ42615194
A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complexQ43405696
P433issue1-2
P921main subjectmultiple sclerosisQ8277
P304page(s)9-36
P577publication date1999-01-01
P1433published inInternational Reviews of ImmunologyQ6052764
P1476titleT cell receptor V genes in multiple sclerosis: increased use of TCRAV8 and TCRBV5 in MBP-specific clones
P478volume18