Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1

scientific article

Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.74.15.7005-7015.2000
P932PMC publication ID112217
P698PubMed publication ID10888639
P5875ResearchGate publication ID12429781

P2093author name stringD Kabat
E J Platt
S E Kuhmann
S L Kozak
P2860cites workRoles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1Q22003751
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivityQ36873079
The adsorption of coliphage lambda to its host: Effect of variations in the surface density of receptor and in phage-receptor affinityQ38359591
Morphogenesis and morphology of HIV. Structure-function relationsQ38677045
HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptorQ38908745
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activityQ38911711
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entryQ38977702
A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5Q39000358
Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptorsQ39110633
Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion.Q39355095
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificityQ39413074
A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.Q39460971
CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domainsQ39549575
Alanine substitutions of polar and nonpolar residues in the amino-terminal domain of CCR5 differently impair entry of macrophage- and dualtropic isolates of human immunodeficiency virus type 1.Q39579651
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.Q39605077
Exceptional fusogenicity of Chinese hamster ovary cells with murine retroviruses suggests roles for cellular factor(s) and receptor clusters in the membrane fusion processQ39874520
Minimal aggregate size and minimal fusion unit for the first fusion pore of influenza hemagglutinin-mediated membrane fusionQ40156309
Critical role of enhanced CD4 affinity in laboratory adaptation of human immunodeficiency virus type 1.Q40870962
Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor functionQ40964911
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.Q41151327
Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell linesQ41157521
Factors underlying spontaneous inactivation and susceptibility to neutralization of human immunodeficiency virusQ41611077
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entryQ43694761
HIV requires multiple gp120 molecules for CD4-mediated infectionQ44171806
Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokinesQ46722581
Chemokine receptors: keys to AIDS pathogenesis?Q47964346
The organization of the envelope projections on the surface of HIVQ53043052
Role of CD4 and CCR5 Levels in the Susceptibility of Primary Macrophages to Infection by CCR5-Dependent HIV Type 1 IsolatesQ59661561
Identification of a major co-receptor for primary isolates of HIV-1Q22251282
Physics of chemoreceptionQ24546294
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyQ27759364
A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactorsQ28118386
HIV entry and its inhibitionQ28273919
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolatesQ28282895
CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domainsQ28646662
CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1Q28646859
A conserved HIV gp120 glycoprotein structure involved in chemokine receptor bindingQ28646883
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor geneQ29614892
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infectionQ29614956
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Q29616094
Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.Q29622903
Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimersQ30442203
Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genesQ33634507
Will multiple coreceptors need to be targeted by inhibitors of human immunodeficiency virus type 1 entry?Q33645423
Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5Q33647608
CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infectionQ33782193
Multiple residues contribute to the inability of murine CCR-5 to function as a coreceptor for macrophage-tropic human immunodeficiency virus type 1 isolatesQ33782312
Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparansQ33782608
Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1Q33784182
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.Q34445208
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.Q34448190
Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1.Q35833860
CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1.Q35876191
Polymorphisms in the CCR5 genes of African green monkeys and mice implicate specific amino acids in infections by simian and human immunodeficiency virusesQ35898770
Dilation of the influenza hemagglutinin fusion pore revealed by the kinetics of individual cell-cell fusion eventsQ36237488
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophagesQ36340560
Change in coreceptor use correlates with disease progression in HIV-1--infected individualsQ36376800
CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitroQ36377185
Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine bindingQ36380755
Constitutive cell surface association between CD4 and CCR5.Q36397946
Differences in CD4 dependence for infectivity of laboratory-adapted and primary patient isolates of human immunodeficiency virus type 1.Q36632478
Dissociation of HIV-1 from follicular dendritic cells during HAART: mathematical analysisQ36773750
P433issue15
P921main subjectcooperationQ380962
P304page(s)7005-7015
P577publication date2000-08-01
P1433published inJournal of VirologyQ1251128
P1476titleCooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1
P478volume74

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cites work (P2860)
Q39152233"Fusion and binding inhibition" key target for HIV-1 treatment and pre-exposure prophylaxis: targets, drug delivery and nanotechnology approaches.
Q35263959A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors
Q28475890Accelerated immunodeficiency by anti-CCR5 treatment in HIV infection
Q34610959Adaptive mutations in a human immunodeficiency virus type 1 envelope protein with a truncated V3 loop restore function by improving interactions with CD4.
Q33870292Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated region
Q40563193Adsorption and infectivity of human immunodeficiency virus type 1 are modified by the fluidity of the plasma membrane for multiple-site binding
Q28485983Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity
Q39682931Altering expression levels of human immunodeficiency virus type 1 gp120-gp41 affects efficiency but not kinetics of cell-cell fusion
Q41996301An allosteric rheostat in HIV-1 gp120 reduces CCR5 stoichiometry required for membrane fusion and overcomes diverse entry limitations
Q44058307An anti-CCR5 monoclonal antibody and small molecule CCR5 antagonists synergize by inhibiting different stages of human immunodeficiency virus type 1 entry
Q34187261Analysis of the functional relationship between V3 loop and gp120 context with regard to human immunodeficiency virus coreceptor usage using naturally selected sequences and different viral backbones.
Q33845055Antigenically distinct conformations of CXCR4.
Q34574462Attachment and Fusion Inhibitors Potently Prevent Dendritic Cell-Driven HIV Infection
Q38934421Binding of fusion protein FLSC IgG1 to CCR5 is enhanced by CCR5 antagonist Maraviroc.
Q39240591Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5.
Q36370878Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains
Q34574397CCR5 antibodies HGS004 and HGS101 preferentially inhibit drug-bound CCR5 infection and restore drug sensitivity of Maraviroc-resistant HIV-1 in primary cells
Q38329768CCR5 promoter haplotype transcription complex characterization
Q39605953CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells
Q41860559CCR5Delta32 protein expression and stability are critical for resistance to human immunodeficiency virus type 1 in vivo
Q39015489CD4 and CCR5 constitutively interact at the plasma membrane of living cells: a confocal fluorescence resonance energy transfer-based approach
Q40081130CD4 interacts constitutively with multiple CCR5 at the plasma membrane of living cells. A fluorescence recovery after photobleaching at variable radii approach.
Q33848876CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain
Q37839350Cell entry of enveloped viruses.
Q36296739Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands
Q35985849Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.
Q39886418Characterization of HIV-2 chimeric viruses unable to use CCR5 and CXCR4 coreceptors
Q29619744Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus
Q36184275Chemokine receptor internalization and intracellular trafficking
Q37348882Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm
Q37834097Conformational HIV-1 envelope on particulate structures: a tool for chemokine coreceptor binding studies
Q35947621Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching
Q35825546Cooperative subunit interactions within the oligomeric envelope glycoprotein of HIV-1: functional complementation of specific defects in gp120 and gp41.
Q34999203Coreceptor usage and biological phenotypes of HIV-1 isolates
Q44480307DC-SIGN and DC-SIGNR: helping hands for HIV.
Q33840771DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus
Q24601035DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans
Q34139616Dancing to the tune of chemokines
Q57079961Dendrimers as topical microbicides with activity against HIV
Q39149893Determinant for the inhibition of ecotropic murine leukemia virus infection by N-linked glycosylation of the rat receptor
Q34875765Different infectivity of HIV-1 strains is linked to number of envelope trimers required for entry
Q29617562Distribution and three-dimensional structure of AIDS virus envelope spikes
Q43066917Double-edged genetic swords and immunity: lesson from CCR5 and beyond
Q40800273Early intermediates in HIV-1 envelope glycoprotein-mediated fusion triggered by CD4 and co-receptor complexes
Q33504556Early steps of HIV-1 fusion define the sensitivity to inhibitory peptides that block 6-helix bundle formation
Q40468565Effects of virion surface gp120 density on infection by HIV-1 and viral production by infected cells.
Q30499561Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions
Q33283730Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry.
Q36237524Emerging drug targets for antiretroviral therapy
Q44399525Entry Inhibitors SCH-C, RANTES, and T-20 Block HIV Type 1 Replication in Multiple Cell Types
Q39454698Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors
Q41979690Ephrin-B2 expression critically influences Nipah virus infection independent of its cytoplasmic tail
Q28478341Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion
Q40219338Feline leukemia virus T entry is dependent on both expression levels and specific interactions between cofactor and receptor
Q33854213Frequent substitution polymorphisms in African green monkey CCR5 cluster at critical sites for infections by simian immunodeficiency virus SIVagm, implying ancient virus-host coevolution
Q40127843Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion
Q36891039G541R within the 4070A TM Protein Regulates Fusion in Murine Leukemia Viruses
Q24338224Gelsolin activity controls efficient early HIV-1 infection
Q28188558HIV coreceptors: role of structure, posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors
Q37945205HIV-1 Entry, Inhibitors, and Resistance
Q22242967HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse
Q35665842HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that are corrected in the presence of drug
Q28344746HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
Q40563186Heterogeneity of envelope molecules shown by different sensitivities to anti-V3 neutralizing antibody and CXCR4 antagonist regulates the formation of multiple-site binding of HIV-1.
Q91945548How virus size and attachment parameters affect the temperature sensitivity of virus binding to host cells: Predictions of a thermodynamic model for arboviruses and HIV
Q37102101Human Immunodeficiency Virus Immune Cell Receptors, Coreceptors, and Cofactors: Implications for Prevention and Treatment.
Q40133069Human immunodeficiency virus type 1 enters primary human brain microvascular endothelial cells by a mechanism involving cell surface proteoglycans independent of lipid rafts
Q39683422Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells
Q34234127Human immunodeficiency virus type-1 and chemokines: beyond competition for common cellular receptors
Q34465007Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins
Q34800822Increasing hydrophobicity of residues in an anti-HIV-1 Env peptide synergistically improves potency
Q39870010Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities
Q35709090Inhibiting sexual transmission of HIV-1 infection
Q36631937Inhibition of HIV-1 entry by antibodies: potential viral and cellular targets
Q33707328Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus
Q40292970Linkage of reduced receptor affinity and superinfection to pathogenesis of TR1.3 murine leukemia virus
Q34859370Localization of CD4 and CCR5 in living cells
Q39521282Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion.
Q41752911Mathematical model of multivalent virus-antibody complex formation in humans following acute and chronic HIV infections
Q39106404Maturation of the viral core enhances the fusion of HIV-1 particles with primary human T cells and monocyte-derived macrophages
Q30448451Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factor
Q37263225Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses
Q38246407Membrane organization of virus and target cell plays a role in HIV entry.
Q39755287Mobility of the human immunodeficiency virus (HIV) receptor CD4 and coreceptor CCR5 in living cells: implications for HIV fusion and entry events
Q41967451Modeling how many envelope glycoprotein trimers per virion participate in human immunodeficiency virus infectivity and its neutralization by antibody
Q21559473Molecular recognition of CCR5 by an HIV-1 gp120 V3 loop
Q40505451Multiple residues in the extracellular domains of CCR3 are critical for coreceptor activity
Q46040511Multistage adsorption of diffusing macromolecules and viruses
Q33846366Mutations within the putative membrane-spanning domain of the simian immunodeficiency virus transmembrane glycoprotein define the minimal requirements for fusion, incorporation, and infectivity
Q34187142Oligomeric beta-structure of the membrane-bound HIV-1 fusion peptide formed from soluble monomers
Q40544036Optimisation of the degree of sulfation of a polymer based construct to block the entry of HIV-1 into cells
Q27321418P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions
Q37104590Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes
Q24673772Pit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentration
Q36195192Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus
Q93115348Predominance of the heterozygous CCR5 delta-24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface
Q35020532Progressive truncations C terminal to the membrane-spanning domain of simian immunodeficiency virus Env reduce fusogenicity and increase concentration dependence of Env for fusion
Q39785030Quantifying the relationship between HIV-1 susceptibility to CCR5 antagonists and virus affinity for antagonist-occupied co-receptor
Q39118166Raft localization of CXCR4 is primarily required for X4-tropic human immunodeficiency virus type 1 infection
Q33676520Rapid dissociation of HIV-1 from cultured cells severely limits infectivity assays, causes the inactivation ascribed to entry inhibitors, and masks the inherently high level of infectivity of virions
Q35146136Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors
Q34010373Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins.
Q39069264Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1.
Q37121416Recruitment of HIV-1 envelope occurs subsequent to lipid mixing: a fluorescence microscopic evidence
Q37068522Reduction of CCR5 with low-dose rapamycin enhances the antiviral activity of vicriviroc against both sensitive and drug-resistant HIV-1.
Q36944098Regulation of human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activity
Q28237665Regulation of the immune response by the interaction of chemokines and proteases
Q57372060Rescue of HIV-1 Receptor Function through Cooperation between Different Forms of the CCR5 Chemokine Receptor
Q37185404Resistance to human immunodeficiency virus type 1 (HIV-1) generated by lentivirus vector-mediated delivery of the CCR5{Delta}32 gene despite detectable expression of the HIV-1 co-receptors
Q39056684Restriction of multiple divergent retroviruses by Lv1 and Ref1
Q37713831Reversible and efficient activation of HIV-1 cell entry by a tyrosine-sulfated peptide dissects endocytic entry and inhibitor mechanisms
Q40471343Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef
Q24608200Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cells
Q34348930Role for human immunodeficiency virus type 1 membrane cholesterol in viral internalization
Q30865013Role of cholesterol in human immunodeficiency virus type 1 envelope protein-mediated fusion with host cells
Q34330529Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus
Q34415921Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
Q36078450Short Communication: HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1
Q34354324Similar regulation of cell surface human T-cell leukemia virus type 1 (HTLV-1) surface binding proteins in cells highly and poorly transduced by HTLV-1-pseudotyped virions
Q42283259Simulations reveal that the HIV-1 gp120-CD4 complex dissociates via complex pathways and is a potential target of the polyamidoamine (PAMAM) dendrimer
Q35906141Stochastic entry of enveloped viruses: fusion versus endocytosis
Q90438646Stoichiometric Analyses of Soluble CD4 to Native-like HIV-1 Envelope by Single-Molecule Fluorescence Spectroscopy
Q42177914Stoichiometric parameters of HIV-1 entry
Q33737656Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.
Q30447936Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1
Q38050485Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.
Q37902736Structure and working of viral fusion machinery
Q39161979Synergistic inhibition of R5 HIV-1 by maraviroc and CCR5 antibody HGS004 in primary cells: implications for treatment and prevention
Q33846502Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry.
Q40384583Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion
Q28188544The HIV Env-mediated fusion reaction
Q37131419The origins of diversity and specificity in g protein-coupled receptor signaling
Q41345703The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment
Q34695601The temperature arrested intermediate of virus-cell fusion is a functional step in HIV infection
Q36156531The trinity of the cortical actin in the initiation of HIV-1 infection
Q35741691The tyrosine kinase inhibitor genistein blocks HIV-1 infection in primary human macrophages
Q34148120Time-resolved imaging of HIV-1 Env-mediated lipid and content mixing between a single virion and cell membrane
Q91912876Towards a thermodynamic mechanistic model for the effect of temperature on arthropod vector competence for transmission of arboviruses
Q36607127Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
Q39031676Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome
Q33707333Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan
Q37941707Viral infection: Moving through complex and dynamic cell-membrane structures.
Q30493649Virological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibition
Q91909222[CCR5 antagonists and HIV-1 infection: Bases and consequences of this therapeutic approach]

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