G541R within the 4070A TM Protein Regulates Fusion in Murine Leukemia Viruses

scientific article published on November 1, 2003

G541R within the 4070A TM Protein Regulates Fusion in Murine Leukemia Viruses is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.77.22.12011-12021.2003
P953full work available at URLhttps://europepmc.org/articles/PMC254290
https://jvi.asm.org/content/77/22/12011.full.pdf
https://europepmc.org/articles/PMC254290?pdf=render
https://doi.org/10.1128/jvi.77.22.12011-12021.2003
https://journals.asm.org/doi/pdf/10.1128/JVI.77.22.12011-12021.2003
P932PMC publication ID254290
P698PubMed publication ID14581538
P5875ResearchGate publication ID9037021

P2093author name stringLucille O'Reilly
Monica J. Roth
P2860cites workNucleic Acids ResearchQ135122
Propagating conformational changes over long (and short) distances in proteinsQ24555781
Structure and mechanism of a coreceptor for infection by a pathogenic feline retrovirusQ27640367
Retrovirus envelope domain at 1.7 angstrom resolutionQ27732659
Receptor interference groups of 20 retroviruses plating on human cellsQ28258709
Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.Q29622903
Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimersQ30442203
Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus.Q33646515
Characterization of the proline-rich region of murine leukemia virus envelope protein.Q33784874
A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopesQ33786094
Activation of a cell entry pathway common to type C mammalian retroviruses by soluble envelope fragmentsQ33794864
Second-site changes affect viability of amphotropic/ecotropic chimeric enveloped murine leukemia virusesQ33796518
Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1Q33808920
Suppression of a fusion defect by second site mutations in the ecotropic murine leukemia virus surface proteinQ33814294
Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 associationQ33843696
Comprehensive mutational analysis of the Moloney murine leukemia virus envelope proteinQ33850227
Activation of membrane fusion by murine leukemia viruses is controlled in cis or in trans by interactions between the receptor-binding domain and a conserved disulfide loop of the carboxy terminus of the surface glycoproteinQ33851195
Efficient cell infection by Moloney murine leukemia virus-derived particles requires minimal amounts of envelope glycoproteinQ33874144
Sulfhydryl involvement in fusion mechanismsQ33917135
Relationship between SU subdomains that regulate the receptor-mediated transition from the native (fusion-inhibited) to the fusion-active conformation of the murine leukemia virus glycoproteinQ34347594
Modular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infectionQ35056161
Mutations within a putative cysteine loop of the transmembrane protein of an attenuated immunodeficiency-inducing feline leukemia virus variant inhibit envelope protein processingQ35837311
The amphotropic and ecotropic murine leukemia virus envelope TM subunits are equivalent mediators of direct membrane fusion: implications for the role of the ecotropic envelope and receptor in syncytium formation and viral entryQ35851220
Characterization of chimeras between the ecotropic Moloney murine leukemia virus and the amphotropic 4070A envelope proteinsQ35860468
Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env proteinQ36629882
A point mutation in the env gene of a murine leukemia virus induces syncytium formation and neurologic diseaseQ36637315
Mutational analysis of the envelope gene of Moloney murine leukemia virusQ36648415
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface densityQ36688770
Mutational analysis of the N-linked glycosylation sites of the SU envelope protein of Moloney murine leukemia virusQ36698884
A neutralizable epitope common to the envelope glycoproteins of ecotropic, polytropic, xenotropic, and amphotropic murine leukemia virusesQ36796266
Effect of changes in expression of the amphotropic retroviral receptor PiT-2 on transduction efficiency and viral titer: implications for gene therapyQ38314314
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Induction of syncytia by neuropathogenic murine leukemia viruses depends on receptor density, host cell determinants, and the intrinsic fusion potential of envelope protein.Q39596546
Functional characterization of the N termini of murine leukemia virus envelope proteinsQ39602502
Altering expression levels of human immunodeficiency virus type 1 gp120-gp41 affects efficiency but not kinetics of cell-cell fusionQ39682931
G100R mutation within 4070A murine leukemia virus Env increases virus receptor binding, kinetics of entry, and viral transduction efficiencyQ39698483
Distinct mechanisms of neutralization by monoclonal antibodies specific for sites in the N-terminal or C-terminal domain of murine leukemia virus SUQ39736690
Functional dissection of the Moloney murine leukemia virus envelope protein gp70.Q39878576
Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymesQ39881687
The presence of disulfide-linked gp70-pl5(E) complexes in AKR murine leukemia virusQ40115195
Virus-receptor interaction in the adenovirus system: characterization of the positive cooperative binding of virions on HeLa cellsQ40135308
The nature of the association between the murine leukemia virus envelope proteinsQ40206975
A transient three-plasmid expression system for the production of high titer retroviral vectorsQ40393091
Functional interaction between the N- and C-terminal domains of murine leukemia virus surface envelope proteinQ40642210
Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane proteinQ41133617
The pH independence of mammalian retrovirus infectionQ41738977
Structural domains of endogenous murine leukemia virus gp70s containing specific antigenic determinants defined by monoclonal antibodiesQ45805304
Identification of conformational and cold-sensitive mutations in the MuLV envelope proteinQ73811636
Plaque assay techniques for murine leukemia virusesQ93694433
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
microbiologyQ7193
immunologyQ101929
membrane fusionQ6556360
P304page(s)12011-12021
P577publication date2003-11-01
P1433published inJournal of VirologyQ1251128
P1476titleG541R within the 4070A TM protein regulates fusion in murine leukemia viruses
G541R within the 4070A TM Protein Regulates Fusion in Murine Leukemia Viruses
P478volume77

Reverse relations

cites work (P2860)
Q39491563Escape from R-peptide deletion in a γ-retrovirus
Q30634144HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus
Q34069822MLV based viral-like-particles for delivery of toxic proteins and nuclear transcription factors
Q33242564Selection of feline leukemia virus envelope proteins from a library by functional association with a murine leukemia virus envelope
Q42005605The MuLV 4070A G541R Env mutation decreases the stability and alters the conformation of the TM ectodomain

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