Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome

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Insufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCRESAHA.109.206052
P932PMC publication ID2859828
P698PubMed publication ID20035083
P5875ResearchGate publication ID40774224

P50authorCornelia WeyandQ87638981
P2093author name stringJörg J Goronzy
Sergey Pryshchep
Susmita Parashar
P2860cites workUnusual CD4+CD28null T lymphocytes and recurrence of acute coronary eventsQ40166868
A novel SHP-1/Grb2-dependent mechanism of negative regulation of cytokine-receptor signaling: contribution of SHP-1 C-terminal tyrosines in cytokine signalingQ40627360
In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern.Q40696454
Monoclonal T-cell proliferation and plaque instability in acute coronary syndromesQ42628689
CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitopeQ44937301
T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome.Q51983441
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Natural regulatory T cells control the development of atherosclerosis in miceQ58149268
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Statins as a newly recognized type of immunomodulatorQ73252634
T-cell-mediated lysis of endothelial cells in acute coronary syndromesQ77595337
Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alphaQ79372327
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signalingQ25257443
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinasesQ28143793
Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque ruptureQ28212820
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Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.Q30157747
Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylationQ32058522
Chromosomal territory segmentation in apoptotic cellsQ33187551
Apoptosis of vascular smooth muscle cells in vascular remodelling and atherosclerotic plaque ruptureQ33643446
Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritisQ33706812
T cell activation and the cytoskeletonQ33932683
Signal transduction mediated by the T cell antigen receptor: the role of adapter proteinsQ34115639
In vivo activation of antigen-specific CD4 T cells.Q34178091
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoproteinQ34390132
Control of T cell function by positive and negative regulatorsQ34662618
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cellsQ34963679
CD45: a critical regulator of signaling thresholds in immune cellsQ34987899
Transmembrane adaptor proteins: organizers of immunoreceptor signallingQ35852278
Atherosclerosis and the immune system.Q36035955
TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaqueQ36227892
Requirement for tyrosine residues 315 and 319 within zeta chain-associated protein 70 for T cell developmentQ36369507
Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.Q36369780
The immune response in atherosclerosis: a double-edged swordQ36508676
Inflammation and plaque vulnerabilityQ37307660
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and toleranceQ37416254
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectacute coronary syndromeQ266018
P304page(s)769-778
P577publication date2009-12-24
P1433published inCirculation ResearchQ2599020
P1476titleInsufficient deactivation of the protein tyrosine kinase lck amplifies T-cell responsiveness in acute coronary syndrome
P478volume106

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cites work (P2860)
Q30241848Adaptive Immunity Dysregulation in Acute Coronary Syndromes: From Cellular and Molecular Basis to Clinical Implications
Q50774005Altered CD31 expression and activity in helper T cells of acute coronary syndrome patients.
Q37365537Altered Maturation Status and Possible Immune Exhaustion of CD8 T Lymphocytes in the Peripheral Blood of Patients Presenting With Acute Coronary Syndromes
Q36179565CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells
Q37398394Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor.
Q34036703Immune aging and rheumatoid arthritis
Q64923537Integrative analysis of promising molecular biomarkers and pathways for coronary artery disease using WGCNA and MetaDE methods.
Q37821238Ischemia/reperfusion injury: The role of immune cells
Q37390202Quantitative detection of zeta-chain-associated protein 70 expression in chronic lymphocytic leukemia
Q37541654SEA antagonizes the imatinib-meditated inhibitory effects on T cell activation via the TCR signaling pathway
Q40067370The immunoinhibitory PD-1/PD-L1 pathway in inflammatory blood vessel disease.
Q26830206What is causing my arthritis, doctor? A glimpse beyond the usual suspects in the pathogenesis of rheumatoid arthritis

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