The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy

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The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YJMCC.2013.10.010
P932PMC publication ID4074493
P698PubMed publication ID24161911

P2093author name stringDomenico M Taglieri
Michelle M Monasky
Kathrin Banach
Bruce R Conklin
Jaime DeSantiago
Brian T Burmeister
Graeme K Carnegie
Matthew J Spindler
Keven R Johnson
P2860cites workmAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytesQ22010409
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Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5Q24561772
AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophyQ27322014
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activationQ28115053
A-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophyQ28116093
AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formationQ28118719
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MEF2: a central regulator of diverse developmental programsQ28254625
Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cyclingQ28268017
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascadeQ28511813
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulumQ28571497
The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in miceQ28574961
AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathwayQ28575625
The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophyQ28579323
Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15Q28582314
Regulation of cardiac hypertrophy by intracellular signalling pathwaysQ29615166
The intermediate filament protein, synemin, is an AKAP in the heartQ33255397
Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-LbcQ33292292
Cardiac troponin T, a sarcomeric AKAP, tethers protein kinase A at the myofilamentsQ33740489
Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen speciesQ34097117
Phosphorylation of HSP27 by protein kinase D is essential for mediating neuroprotection against ischemic neuronal injuryQ34167291
Excitation-contraction coupling in ventricular myocytes is enhanced by paracrine signaling from mesenchymal stem cellsQ34215785
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Cardiac plasticityQ34764732
Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelinQ35312534
Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2AQ35529137
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Identification and mapping of protein kinase A binding sites in the costameric protein myosprynQ35956643
Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heartQ36418877
Requirement of protein kinase D1 for pathological cardiac remodelingQ36498485
Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotypeQ36988687
Protein kinase d in the cardiovascular system: emerging roles in health and disease.Q37073324
Tackling heart failure in the twenty-first centuryQ37089726
A-kinase anchoring proteins: from protein complexes to physiology and diseaseQ37192490
AKAP-scaffolding proteins and regulation of cardiac physiology.Q37362251
Reactive oxygen species decrease cAMP response element binding protein expression in cardiomyocytes via a protein kinase D1-dependent mechanism that does not require Ser133 phosphorylationQ37402785
A-kinase anchoring proteins that regulate cardiac remodelingQ37954942
Transverse aortic constriction in miceQ38272478
Mitochondrial Ca2+ uptake is inhibited by a concerted action of p38 MAPK and protein kinase D.Q39820852
Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteinsQ40503589
AKAP-Lbc nucleates a protein kinase D activation scaffoldQ40512904
RhoA protects the mouse heart against ischemia/reperfusion injuryQ42014677
MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overloadQ43214524
Changes in extracellular collagen matrix alter myocardial systolic performanceQ44251628
Converging pathways and principles in heart development and disease: CV@CSH.Q44398652
Gene trapping methods for the identification and functional analysis of cell surface proteins in miceQ46085169
Increased natriuretic peptide receptor A and C gene expression in rats with pressure-overload cardiac hypertrophyQ46792345
A regulatory SNP in AKAP13 is associated with blood pressure in KoreansQ46964042
Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytesQ50695684
Expression and activity of protein kinase D/protein kinase C mu in myocardium: evidence for alpha1-adrenergic receptor- and protein kinase C-mediated regulation.Q52166952
Regulation of myosin heavy chain and actin isogenes during cardiac growth and hypertrophy.Q52234601
American Society of Echocardiography recommendations for quality echocardiography laboratory operations.Q54320841
Reorganized PKA-AKAP associations in the failing human heart.Q54578401
Myosin heavy chain regulation and myocyte contractile depression after LV hypertrophy in aortic-banded miceQ72101575
Assay of protein kinases using radiolabeled ATP: a protocolQ80092991
Protein kinase D regulates the human cardiac L-type voltage-gated calcium channel through serine 1884Q82594390
P304page(s)27-40
P577publication date2013-10-23
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleThe C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy
P478volume66

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cites work (P2860)
Q50117582A-Kinase Anchoring Protein-Lbc: A Molecular Scaffold Involved in Cardiac Protection
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Q37601331Emergency Spatiotemporal Shift: The Response of Protein Kinase D to Stress Signals in the Cardiovascular System
Q27302945Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy
Q38186583Heart failure-specific changes in protein kinase signalling.
Q27318689RhoA Ambivalently Controls Prominent Myofibroblast Characteritics by Involving Distinct Signaling Routes
Q26781574Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins
Q92327108The Role of Cyclic AMP Signaling in Cardiac Fibrosis

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