| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1014651265 |
| P356 | DOI | 10.1186/1471-2407-14-370 |
| P932 | PMC publication ID | 4076062 |
| P698 | PubMed publication ID | 24885711 |
| P5875 | ResearchGate publication ID | 262789500 |
| P2093 | author name string | Feng Zhou | |
| Chunyou Wang | |||
| Pengfei Cui | |||
| Pengfei Shi | |||
| Shanmiao Gou | |||
| Tao Yin | |||
| P2860 | cites work | Global cancer statistics | Q22241238 |
| Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA | Q24291172 | ||
| The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor | Q24306696 | ||
| Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells | Q28366303 | ||
| Akt1 enhances CA916798 expression through mTOR pathway | Q28487802 | ||
| Targeting PI3K signalling in cancer: opportunities, challenges and limitations | Q29617685 | ||
| Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status | Q33638654 | ||
| Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules | Q34025938 | ||
| Anti-tumor mechanisms of valproate: a novel role for an old drug | Q34147644 | ||
| Retracted: 3, 3'-Diindolylmethane Exhibits Antileukemic Activity In Vitro and In Vivo through a Akt-Dependent Process | Q34171365 | ||
| Unravelling natural killer cell function: triggering and inhibitory human NK receptors | Q35611389 | ||
| Engineering lymph node homing of ex vivo-expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7. | Q36163212 | ||
| Oncogenic PI3K deregulates transcription and translation | Q36337966 | ||
| Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma | Q36520715 | ||
| Chimeric NKG2D CAR-expressing T cell-mediated attack of human ovarian cancer is enhanced by histone deacetylase inhibition | Q36720681 | ||
| Cytokine-driven regulation of NK cell functions in tumor immunity: role of the MICA-NKG2D system | Q36745910 | ||
| Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB. | Q36790513 | ||
| Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies | Q37926319 | ||
| Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways | Q39340871 | ||
| Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor. | Q39348282 | ||
| HER2/HER3 signaling regulates NK cell-mediated cytotoxicity via MHC class I chain-related molecule A and B expression in human breast cancer cell lines | Q39402352 | ||
| Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia | Q39695762 | ||
| p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment. | Q39706036 | ||
| Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis | Q39760172 | ||
| HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA. | Q39837701 | ||
| ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype | Q39903222 | ||
| Regulation of the expression of MHC class I-related chain A, B (MICA, MICB) via chromatin remodeling and its impact on the susceptibility of leukemic cells to the cytotoxicity of NKG2D-expressing cells | Q40108262 | ||
| Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines | Q40126767 | ||
| TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells | Q40246842 | ||
| In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates | Q40336852 | ||
| Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. | Q40448896 | ||
| Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium | Q42806870 | ||
| Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo | Q43239330 | ||
| Clinical significance of the immunostimulatory MHC class I chain-related molecule A and NKG2D receptor on NK cells in pancreatic cancer | Q44124507 | ||
| Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate | Q46158181 | ||
| Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide | Q46535754 | ||
| Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate | Q46604673 | ||
| Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy. | Q46835743 | ||
| Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells. | Q54455472 | ||
| Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK- cell lysis | Q80092122 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pancreatic cancer | Q212961 |
| P304 | page(s) | 370 | |
| P577 | publication date | 2014-05-25 | |
| P1433 | published in | BMC Cancer | Q326300 |
| P1476 | title | Valproic acid sensitizes pancreatic cancer cells to natural killer cell-mediated lysis by upregulating MICA and MICB via the PI3K/Akt signaling pathway | |
| P478 | volume | 14 |
| Q64968682 | Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function. |
| Q41605713 | Controlling Directed Protein Interaction Networks in Cancer |
| Q37641527 | Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function |
| Q50080994 | Dysbindin promotes progression of pancreatic ductal adenocarcinoma via direct activation of PI3K. |
| Q89798440 | Epithelial-mesenchymal transition may be involved in the immune evasion of circulating gastric tumor cells via downregulation of ULBP1 |
| Q64093968 | Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells |
| Q37229770 | Expression and prognostic significance of unique ULBPs in pancreatic cancer |
| Q36104946 | Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function |
| Q37114711 | Histone deacetylase inhibitor valproic acid (VPA) promotes the epithelial mesenchymal transition of colorectal cancer cells via up regulation of Snail |
| Q55030400 | Immunotherapy With Human Gamma Delta T Cells-Synergistic Potential of Epigenetic Drugs? |
| Q38760434 | Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs |
| Q45759422 | Low-dose valproic acid with low-dose gemcitabine augments MHC class I-related chain A/B expression without inducing the release of soluble MHC class I-related chain A/B. |
| Q97419293 | Metformin inhibits cervical cancer cell proliferation by modulating PI3K/Akt-induced major histocompatibility complex class I-related chain A gene expression |
| Q36285296 | Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach |
| Q38788557 | NKG2D Ligand-Targeted Bispecific T-Cell Engagers Lead to Robust Antitumor Activity against Diverse Human Tumors. |
| Q58750637 | NKG2D Ligands-Critical Targets for Cancer Immune Escape and Therapy |
| Q88016001 | NKG2D and its ligands in cancer |
| Q42042886 | Natural Killer Cell Response to Chemotherapy-Stressed Cancer Cells: Role in Tumor Immunosurveillance. |
| Q36622089 | Overexpression of natural killer group 2 member D ligands predicts favorable prognosis in cholangiocarcinoma |
| Q37247500 | Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer |
| Q54980764 | Phosphoinositide 3-Kinase Signaling Pathway in Pancreatic Ductal Adenocarcinoma Progression, Pathogenesis, and Therapeutics. |
| Q53613478 | Platelet-derived TGF-β1 mediates the down-modulation of NKG2D expression and may be responsible for impaired natural killer (NK) cytotoxicity in women with endometriosis. |
| Q99406942 | Refocusing the Use of Psychiatric Drugs for Treatment of Gastrointestinal Cancers |
| Q33815894 | Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer |
| Q92150920 | Strategies to Augment Natural Killer (NK) Cell Activity against Solid Tumors |
| Q37719306 | The histone deacetylase inhibitor valproic acid inhibits NKG2D expression in natural killer cells through suppression of STAT3 and HDAC3. |
| Q36010627 | Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells |
| Q35799192 | γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy? |
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