| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0167-5699(99)01552-2 |
| P698 | PubMed publication ID | 10652465 |
| P50 | author | Douglas R. Green | Q19667788 |
| P2093 | author name string | P P Tak | |
| G S Firestein | |||
| N J Zvaifler | |||
| P2860 | cites work | P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis | Q71395532 |
| Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease | Q71720530 | ||
| Enhanced cellular proliferation and p53 accumulation in gastric mucosa chronically infected with Helicobacter pylori | Q73480213 | ||
| Topographical association between the cyclin-dependent kinases inhibitor P21, p53 accumulation, and cellular proliferation in human atherosclerotic tissue | Q73832976 | ||
| Mutations of the p53 tumour suppressor gene in erosive rheumatoid synovial tissue | Q74255888 | ||
| Dysregulation of apoptosis in the cholangiopathies and cholangiocarcinoma | Q74600447 | ||
| p53 and p21(WAF1) expression in lymphocytic thyroiditis and thyroid tumors | Q77135756 | ||
| p53 down-regulates human matrix metalloproteinase-1 (Collagenase-1) gene expression | Q77335893 | ||
| Monoclonal expansion of synoviocytes in rheumatoid arthritis | Q77539463 | ||
| Analysis of the p53 tumor suppressor gene in rheumatoid arthritis synovial fibroblasts | Q78124701 | ||
| Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours | Q29618396 | ||
| Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases | Q33565771 | ||
| Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases | Q33584105 | ||
| p53 expression during normal tissue regeneration in response to acute cutaneous injury in swine | Q34146568 | ||
| Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids | Q34570627 | ||
| Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis | Q35745296 | ||
| Apoptosis in rheumatoid arthritis synovium | Q35763587 | ||
| Mutagenesis associated with nitric oxide production in macrophages | Q36174298 | ||
| Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. | Q36600496 | ||
| Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. | Q37694644 | ||
| Carcinomas of the renal pelvis associated with smoking and phenacetin abuse: p53 mutations and polymorphism of carcinogen-metabolising enzymes | Q38470858 | ||
| Mutational spectrum in the p53 gene in bladder tumors from the endemic area of black foot disease in Taiwan | Q38483420 | ||
| Detection of p53 in inflammatory tissue and lymphocytes using immunohistology and flow cytometry: a critical comment | Q39574104 | ||
| Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours | Q39579518 | ||
| In situ characterization of inflammatory responses in the rectal mucosae of patients with shigellosis. | Q39833303 | ||
| Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis | Q40386904 | ||
| Hypoxia, oxidative stress and rheumatoid arthritis | Q40409074 | ||
| Oxygen radicals, nitric oxide and human inflammatory joint disease | Q40458496 | ||
| HPRT- mutant T cells in the peripheral blood and synovial tissue of patients with rheumatoid arthritis | Q41002052 | ||
| Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors? | Q41206012 | ||
| Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining | Q41661064 | ||
| p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis | Q41664212 | ||
| Dominant-negative p53 mutations in rheumatoid arthritis | Q41671777 | ||
| Apoptosis by p53: mechanisms, regulation, and clinical implications | Q41737530 | ||
| Overexpression of p53 protein during pancreatitis | Q41911268 | ||
| Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients | Q42943792 | ||
| p53 induction by tumor necrosis factor-alpha and involvement of p53 in cell death of human oligodendrocytes. | Q48149048 | ||
| Sunburn and p53 in the onset of skin cancer | Q59067136 | ||
| H-ras oncogene point mutations in arthritic synovium | Q60375189 | ||
| Expression of the thioredoxin-thioredoxin reductase system in the inflamed joints of patients with rheumatoid arthritis | Q63406968 | ||
| Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black | Q71052895 | ||
| Elevated nitric oxide production in rheumatoid arthritis. Detection using the fasting urinary nitrate:creatinine ratio | Q71077866 | ||
| P433 | issue | 2 | |
| P921 | main subject | rheumatoid arthritis | Q187255 |
| P304 | page(s) | 78-82 | |
| P577 | publication date | 2000-02-01 | |
| P1433 | published in | Trends in Immunology | Q15265730 |
| P1476 | title | Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases | |
| P478 | volume | 21 |
| Q42152810 | A microfluidic systems biology approach for live single-cell mitochondrial ROS imaging |
| Q54419222 | A network pharmacology approach to determine the synergetic mechanisms of herb couple for treating rheumatic arthritis. |
| Q36956438 | Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation |
| Q42951400 | An Extract of thePleurotus ostreatusMushroom Bolsters the Glutathione Redox System in Various Organs of Aged Rats |
| Q42149019 | Analysis of synovial biopsy samples: opportunities and challenges |
| Q28364842 | Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA |
| Q24674100 | Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples from patients with end stage, destructive rheumatoid arthritis |
| Q36281697 | Anti-arthritic property of crude extracts of Piptadeniastrum africanum (Mimosaceae) in complete Freund's adjuvant-induced arthritis in rats |
| Q36022284 | Antioxidant Potential of Vespa affinis L., a Traditional Edible Insect Species of North East India |
| Q24792387 | Apoptosis and p53 expression in rat adjuvant arthritis |
| Q34718143 | Apoptosis as a therapeutic tool in rheumatoid arthritis |
| Q90146050 | Association between activity and genotypes of paraoxonase1 L55M (rs854560) increases the disease activity of rheumatoid arthritis through oxidative stress |
| Q42483366 | Attenuation of oxidative stress by allylpyrocatechol in synovial cellular infiltrate of patients with Rheumatoid Arthritis. |
| Q24804174 | Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis |
| Q35059951 | Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses |
| Q24817108 | Characterization of histopathology and gene-expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specimens |
| Q79304445 | Chronicity of pristane-induced arthritis in rats is controlled by genes on chromosome 14 |
| Q39614400 | Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment |
| Q34135765 | Creation of psoriatic plaques: the ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint |
| Q24804893 | Current perspectives on synovitis |
| Q36546471 | DNA methylome signature in rheumatoid arthritis |
| Q35792008 | Detection of oncofetal h19 RNA in rheumatoid arthritis synovial tissue |
| Q30847952 | Development of a new assay for the screening of hypochlorous acid scavengers based on reversed-phase high-performance liquid chromatography |
| Q37282265 | Dietary antioxidants in inflammatory arthritis: do they have any role in etiology or therapy? |
| Q24795223 | Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats |
| Q45345449 | Direct transcriptional activation of human caspase-1 by tumor suppressor p53. |
| Q35833797 | Discovery of serum proteomic biomarkers for prediction of response to moxibustion treatment in rats with collagen-induced arthritis: an exploratory analysis |
| Q38059458 | Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors |
| Q44082895 | Dysfunction of peripheral blood granulocyte oxidative metabolism in children with recurrent upper respiratory tract infections |
| Q41829205 | Dysregulated bioenergetics: a key regulator of joint inflammation. |
| Q40689499 | Early onset of lipid peroxidation after human traumatic brain injury: a fatal limitation for the free radical scavenger pharmacological therapy? |
| Q90216318 | Effect of electroacupuncture at the ST36 and GB39 acupoints on apoptosis by regulating the p53 signaling pathway in adjuvant arthritis rats |
| Q44030000 | Effects of synovial fluid on the respiratory burst of granulocytes in rheumatoid arthritis. |
| Q35683210 | Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study |
| Q38986705 | Epigenetic drug discovery: breaking through the immune barrier |
| Q39625508 | Exposure of HEp-2 cells to stress conditions influences antinuclear antibody reactivity |
| Q24812237 | Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis |
| Q64980914 | Expression profiling of genes in rheumatoid fibroblast-like synoviocytes regulated by tumor necrosis factor-like ligand 1A using cDNA microarray analysis. |
| Q24797514 | Extracellular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis |
| Q42548726 | Fanconi anemia proteins and endogenous stresses |
| Q43039314 | Functional analysis of the p53 codon 72 polymorphism in black South Africans with rheumatoid arthritis--a pilot study |
| Q35122176 | Gene therapy for arthritis |
| Q24796801 | Gene therapy in animal models of rheumatoid arthritis: are we ready for the patients? |
| Q37911558 | Glycolysis and rheumatoid arthritis. |
| Q34526821 | How important are T cells in chronic rheumatoid synovitis?: II. T cell-independent mechanisms from beginning to end. |
| Q59042062 | Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis |
| Q36084438 | Hypoxia inducible factor (HIF) in rheumatology: low O2! See what HIF can do! |
| Q38844323 | Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis |
| Q46914146 | Identification of clinical parameters associated with serum oxidative stress in patients with rheumatoid arthritis |
| Q88933245 | Identification of key genes in rheumatoid arthritis and osteoarthritis based on bioinformatics analysis |
| Q35551659 | Identification of the advanced glycation end products N(epsilon)-carboxymethyllysine in the synovial tissue of patients with rheumatoid arthritis |
| Q28071935 | Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment |
| Q49959079 | Impact of novel N-aryl piperamide NO donors on NF-κB translocation in neuroinflammation: rational drug-designing synthesis and biological evaluation. |
| Q39092091 | Iron overload and altered iron metabolism in ovarian cancer |
| Q53052194 | JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis. |
| Q85072453 | MDM4 overexpression contributes to synoviocyte proliferation in patients with rheumatoid arthritis |
| Q38989145 | Macrophage-mediated response to hypoxia in disease |
| Q47810090 | Medicine is not health care, food is health care: plant metabolic engineering, diet and human health |
| Q31126109 | MiR-146a regulates SOD2 expression in H2O2 stimulated PC12 cells |
| Q38121969 | Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases |
| Q43753204 | NF-kappaB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, a modulin from oral streptococci |
| Q44378763 | NF-kappaB-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: potential role in rheumatoid arthritis |
| Q38389967 | New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy. |
| Q41878964 | Nigella sativa Pretreatment in Guinea Pigs Exposed to Cigarette Smoke Modulates In Vitro Tracheal Responsiveness |
| Q42523782 | Oral lichen planus has a high rate of TP53 mutations. A study of oral mucosa in icelanD. |
| Q21195671 | Oxidation in rheumatoid arthritis. |
| Q36265270 | Oxidative stress and calcium-phosphorus levels in Rheumatoid arthritis |
| Q37216681 | Oxidative stress in Fanconi anemia hematopoiesis and disease progression |
| Q38005192 | PBEF/NAMPT/visfatin: a promising drug target for treating rheumatoid arthritis? |
| Q51682592 | PGK1, a glucose metabolism enzyme, may play an important role in rheumatoid arthritis. |
| Q34275992 | Pathogenesis of rheumatoid arthritis: the role of synoviocytes |
| Q36580833 | Plasma and Synovial Fluid TrxR Levels are Correlated With Disease Risk and Severity in Patients With Rheumatoid Arthritis |
| Q42290227 | Protective Effect of Pinitol Against Inflammatory Mediators of Rheumatoid Arthritis via Inhibition of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22). |
| Q40750482 | Protective effect of L-carnosine against 12-O-tetradecanoylphorbol-13-acetate- or hydrogen peroxide-induced apoptosis on v-myc transformed rat liver epithelial cells |
| Q92078915 | RA-map: building a state-of-the-art interactive knowledge base for rheumatoid arthritis |
| Q53176987 | Radiation-induced inflammation and autoimmune diseases. |
| Q37142186 | Redox signalling and the inflammatory response in rheumatoid arthritis. |
| Q34098828 | Regional analysis of p53 mutations in rheumatoid arthritis synovium |
| Q36553359 | Regulation of DNA methylation in rheumatoid arthritis synoviocytes |
| Q35788653 | Regulation of joint destruction and inflammation by p53 in collagen-induced arthritis |
| Q94562756 | Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes |
| Q87726283 | Rheumatoid arthritis |
| Q46317472 | Rheumatoid arthritis fibroblast-like synoviocytes co-cultured with PBMC increased peripheral CD4+ CXCR5+ ICOS+ T cell numbers. |
| Q35612472 | Rheumatoid arthritis: regulation of synovial inflammation |
| Q36420808 | Serum level of oxidative stress marker is dramatically low in patients with rheumatoid arthritis treated with tocilizumab |
| Q46458701 | Serum level of reactive oxygen metabolites (ROM) at 12 weeks of treatment with biologic agents for rheumatoid arthritis is a novel predictor for 52-week remission |
| Q80179225 | Serum oxidative-antioxidative status in patients with ankylosing spondilitis |
| Q34358419 | Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis |
| Q33942815 | Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide |
| Q24817118 | Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes |
| Q28080864 | Stress, oxidative injury and disease |
| Q39830600 | Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis |
| Q45293343 | Supplementation with gliadin-combined plant superoxide dismutase extract promotes antioxidant defences and protects against oxidative stress |
| Q35893385 | Survivin is an essential mediator of arthritis interacting with urokinase signalling |
| Q99710722 | Synergy between 15-lipoxygenase and secreted PLA2 promotes inflammation by formation of TLR4 agonists from extracellular vesicles |
| Q73697305 | Synovial fibroblasts and synovial macrophages from patients with rheumatoid arthritis and other inflammatory joint diseases show chromosomal aberrations |
| Q44911297 | Targeting cathepsin L (CL) by specific ribozymes decreases CL protein synthesis and cartilage destruction in rheumatoid arthritis. |
| Q37317209 | Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? |
| Q39366944 | The Potential of Circadian Realignment in Rheumatoid Arthritis |
| Q37350928 | The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue |
| Q47233649 | The Tumor-like Phenotype of Rheumatoid Synovium: Molecular Profiling and Prospects for Precision Medicine |
| Q43220306 | The effect of anti-TNF agent on oxidation status in patients with ankylosing spondylitis |
| Q73223371 | The p53 status in juvenile chronic arthritis and rheumatoid arthritis |
| Q34122715 | The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis |
| Q61053463 | The resolution of inflammation |
| Q36024449 | The role of leukocyte-stromal interactions in chronic inflammatory joint disease |
| Q24805297 | The stressed synovium |
| Q43884059 | Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis |
| Q35043885 | Trp53 negatively regulates autoimmunity via the STAT3-Th17 axis |
| Q46758534 | Tumor suppressor protein p53 and anti-p53 autoantibodies in pediatric rheumatological diseases. |
| Q35555195 | p53 expression in rheumatoid and psoriatic arthritis synovial tissue and association with joint damage |
| Q35552291 | p53 in rheumatoid arthritis synovial fibroblasts at sites of invasion |
| Q24806906 | p53 in rheumatoid arthritis: friend or foe? |
| Q24798661 | p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis |
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