scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1029487172 |
P356 | DOI | 10.1038/372773A0 |
P698 | PubMed publication ID | 7997263 |
P50 | author | Annemarie Ziegler | Q67912497 |
P2093 | author name string | Jacks T | |
Brash DE | |||
Leffell DJ | |||
Sharma HW | |||
Simon JA | |||
Remington L | |||
Kimmelman J | |||
Jonason AS | |||
P2860 | cites work | Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation | Q24642901 |
SUNBURN CELL: FACTORS INVOLVED IN ITS FORMATION. | Q29014077 | ||
Mutation selection and the natural history of cancer | Q29614279 | ||
p53 is required for radiation-induced apoptosis in mouse thymocytes | Q29620281 | ||
Mutation and cancer: a model for human carcinogenesis | Q34273649 | ||
The role of childhood exposure to sunlight in the development of solar keratoses and non-melanocytic skin cancer | Q34298538 | ||
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma | Q34982679 | ||
p53 function and dysfunction | Q35721291 | ||
Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. | Q36287125 | ||
Prooxidant states and tumor promotion | Q39492603 | ||
Apoptosis in cancer therapy: crossing the threshold | Q40694262 | ||
Pigmentary and cutaneous risk factors for non-melanocytic skin cancer--a case-control study | Q42477227 | ||
Ultraviolet radiation-induced histopathologic changes in the skin of the marsupial Monodelphis domestica. II. Quantitative studies of the photoreactivation of induced hyperplasia and sunburn cell formation | Q44255208 | ||
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. | Q53478233 | ||
Thymocyte apoptosis induced by p53-dependent and independent pathways. | Q54242475 | ||
Induction of tandem-base change mutations | Q64389702 | ||
Histological changes produced in skin by equally erythemogenic doses of UV-A, UV-B, UV-C and UV-A with psoralens | Q66971005 | ||
Spontaneous remission of solar keratoses: the case for conservative management | Q69714957 | ||
p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin | Q70723921 | ||
Effects of ultraviolet radiation on the mitotic cycle and DNA, RNA and protein synthesis in mammalian epidermis in vivo | Q71639852 | ||
P433 | issue | 6508 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | skin cancer | Q192102 |
P304 | page(s) | 773-776 | |
P577 | publication date | 1994-12-01 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Sunburn and p53 in the onset of skin cancer | |
P478 | volume | 372 |
Q33243825 | (-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repair |
Q37589207 | 30 years and a long way into p53 research |
Q61988951 | 5-Methylcytosine at HpaII sites in p53 is not hypermutable after UVC irradiation |
Q49237081 | A 32P-postlabeling assay for the oxidative DNA lesion 8,5'-cyclo-2'-deoxyadenosine in mammalian tissues: evidence that four type II I-compounds are dinucleotides containing the lesion in the 3' nucleotide |
Q81197691 | A caspase-resistant mutant of PKC-delta protects keratinocytes from UV-induced apoptosis |
Q38778567 | A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma |
Q36439842 | A comprehensive genetic approach for improving prediction of skin cancer risk in humans |
Q37138063 | A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosis |
Q35659439 | A humanized stromal bed is required for engraftment of isolated human primary squamous cell carcinoma cells in immunocompromised mice |
Q28507498 | A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen |
Q36135100 | A non-random deletion in the p53 gene in oral squamous cell carcinoma |
Q39714583 | A p38(MAPK)/HIF-1 pathway initiated by UVB irradiation is required to induce Noxa and apoptosis of human keratinocytes |
Q38007015 | A review of actinic keratosis for the nurse practitioner: diagnosis, treatment, and clinical pearls |
Q34990836 | A transgenic mouse for imaging caspase-dependent apoptosis within the skin |
Q30009543 | ASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63 |
Q34583147 | Absence of p53-dependent apoptosis leads to UV radiation hypersensitivity, enhanced immunosuppression and cellular senescence |
Q53342807 | Actinic cheilitis: histopathology and p53. |
Q73202168 | Actinic keratoses |
Q28206235 | Activation of estrogen receptor alpha and ERbeta by 4-methylbenzylidene-camphor in human and rat cells: comparison with phyto- and xenoestrogens |
Q47352262 | Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibition |
Q27345861 | Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin |
Q34421866 | Acute response of human skin to solar radiation: regulation and function of the p53 protein |
Q42476661 | Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice |
Q36842824 | Advances in dermatologic surgery |
Q34429495 | Ageing and photoageing of keratinocytes and melanocytes |
Q42818650 | Akt1-mediated intracellular oxidation after UVB irradiation suppresses apoptotic cell death induced by cell detachment and serum starvation |
Q33738770 | Alcohol intake-associated skin and mucosal cancer |
Q56418625 | Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia |
Q37436249 | An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion |
Q43202321 | Angiogenic switch occurs late in squamous cell carcinomas of human skin |
Q28829867 | Animal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for 100 Years |
Q53375614 | Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones. |
Q47759494 | Apoptin specifically causes apoptosis in tumor cells and after UV-treatment in untransformed cells from cancer-prone individuals: a review |
Q73468224 | Apoptosis and cutaneous biology |
Q40876219 | Apoptosis and cytokine release induced by ionizing or ultraviolet B radiation in primary and immortalized human keratinocytes |
Q44450105 | Apoptosis and efficient repair of DNA damage protect human keratinocytes against UVB. |
Q33846227 | Apoptosis in cancer |
Q35782687 | Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium. |
Q31063031 | Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1). |
Q34017186 | Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing. |
Q24812439 | Arsenite cocarcinogenesis: an animal model derived from genetic toxicology studies |
Q47759057 | Association of loss of heterozygosity at the p53 locus with chemoresistance in osteosarcomas |
Q33837827 | Autocrine nerve growth factor in human keratinocytes. |
Q45289318 | Azathioprine treatment photosensitizes human skin to ultraviolet A radiation. |
Q89254667 | BMAL1 and CLOCK proteins in regulating UVB-induced apoptosis and DNA damage responses in human keratinocytes |
Q42482279 | Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice |
Q36090147 | Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling |
Q42548348 | Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin |
Q45382169 | Biophysical modelling of the effects of inhaled radon progeny on the bronchial epithelium for the estimation of the relationships applied in the two-stage clonal expansion model of carcinogenesis. |
Q30972352 | Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts |
Q33952947 | Brain atrophy and neuronal loss in alcoholism: a role for DNA damage? |
Q48063272 | British Association of Dermatologists' guidelines for the care of patients with actinic keratosis 2017. |
Q37683765 | C/EBPalpha is a DNA damage-inducible p53-regulated mediator of the G1 checkpoint in keratinocytes |
Q53408683 | CC to TT mutation in the mitochondrial DNA of normal skin: relationship to ultraviolet light exposure. |
Q38381763 | Caffeic Acid Inhibits Chronic UVB-Induced Cellular Proliferation Through JAK-STAT3 Signaling in Mouse Skin |
Q35170221 | Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial |
Q53444120 | Can skin cancer in humans be prevented by alleviation of oxidative stress? |
Q40369102 | Cancer progression and p53. |
Q33846175 | Carcinogenesis in mouse and human cells: parallels and paradoxes |
Q40755931 | Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C. |
Q51623974 | Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53(R172H). |
Q53444483 | Cell cycle effects and concomitant p53 expression in hairless murine skin after longwave UVA (365 nm) irradiation: a comparison with UVB irradiation. |
Q41231240 | Cell-mediated immunosuppressive mechanisms induced by UV radiation. |
Q36390333 | Cellular aspects of photocarcinogenesis |
Q71046565 | Cellular proofreading |
Q28611443 | Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM |
Q38854948 | Chemical excitation of electrons: A dark path to melanoma |
Q88644415 | Chemiexcitation and Its Implications for Disease |
Q34552893 | Chemoprevention of human skin cancer |
Q41231346 | Chemoprevention of photocarcinogenesis |
Q34161342 | Chemoprevention of photocarcinogenesis by selected dietary botanicals |
Q39153973 | Chiral ruthenium(II) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα. |
Q35600207 | Chromatin structure following UV-induced DNA damage-repair or death? |
Q61883090 | Chromosome breakpoint distribution in nonmelanoma skin cancers |
Q35159652 | Chromosome instability contributes to loss of heterozygosity in mice lacking p53 |
Q38016495 | Chronic low dose UV exposure and p53 mutation: tilting the odds in early epidermal preneoplasia? |
Q53442280 | Chronic ultraviolet exposure-induced p53 gene alterations in Sencar mouse skin carcinogenesis model. |
Q35601607 | Combination of low calcium with Y-27632 rock inhibitor increases the proliferative capacity, expansion potential and lifespan of primary human keratinocytes while retaining their capacity to differentiate into stratified epidermis in a 3D skin model |
Q34396026 | Comparative immune phenotypic analysis of cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in immune-competent individuals: proportional representation of CD8+ T-cells but not FoxP3+ Regulatory T-cells is associated with disease stage. |
Q44199715 | Comparative studies of the influence of cyclodextrins on the stability of the sunscreen agent, 2-ethylhexyl-p-methoxycinnamate |
Q54957215 | Comparison of P53 Intensity, Frequency and Size in Normal Skin Periphery of Squamous Cell Carcinoma, Basal Cell Carcinoma And Melanocytic Nevus in Persian Skin Type. |
Q63199150 | Complexation of the sunscreen agent, butyl-methoxydibenzoylmethane, with hydroxypropyl-β-cyclodextrin |
Q37561571 | Concurrent beneficial (vitamin D production) and hazardous (cutaneous DNA damage) impact of repeated low-level summer sunlight exposures. |
Q43674459 | Contrasting effects of an ultraviolet B and an ultraviolet A tanning lamp on interleukin-6, tumour necrosis factor-alpha and intercellular adhesion molecule-1 expression |
Q34803514 | Control and target gene selection for studies on UV-induced genotoxicity in whales |
Q73180055 | Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis |
Q52886161 | Correlation between cell cycle proteins and hMSH2 in actinic cheilitis and lip cancer. |
Q34998525 | Cosmeceuticals and silibinin |
Q38177887 | Crosstalk among p53 family members in cutaneous carcinoma. |
Q34997018 | Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes |
Q38547625 | Current concept of photocarcinogenesis |
Q38045433 | Current treatment of cutaneous squamous cancer and molecular strategies for its sensitization to new target-based drugs. |
Q90745209 | Cutaneous Photoprotection: A Review of the Current Status and Evolving Strategies |
Q40100180 | Cutaneous Squamous Cell Carcinoma in Lupus Vulgaris Caused by Drug Resistant Mycobacterium Tuberculosis. |
Q38565672 | Cutaneous basal cell carcinosarcoma: case report and literature review. |
Q34322752 | Cutaneous malignancies of keratinocytic origin |
Q36347508 | Cutaneous melanoma in postmenopausal women after nonmelanoma skin carcinoma: the Women's Health Initiative Observational Study |
Q35209745 | Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round? |
Q34725299 | Cutaneous squamous cell carcinoma of the head and neck |
Q38363738 | Cyclobutylpyrimidine dimer base flipping by DNA photolyase |
Q34097368 | Cyclooxygenase isoforms in human skin |
Q44187313 | Cyclosporin-A suppresses p53-dependent repair DNA synthesis and apoptosis following ultraviolet-B irradiation |
Q37076474 | DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance |
Q44107650 | DNA damage, death receptor activation and reactive oxygen species contribute to ultraviolet radiation-induced apoptosis in an essential and independent way. |
Q37579029 | DNA repair and cytokine responses |
Q41231357 | DNA repair enzymes in prevention of photocarcinogenesis |
Q31823700 | DNA-dependent protein kinase catalytic subunit is cleaved during UV-induced apoptosis |
Q34475613 | Deciphering squamous cell carcinoma using multidimensional genomic approaches |
Q42449807 | Decrease in class pi glutathione transferase mRNA levels by ultraviolet irradiation of cultured rat keratinocytes |
Q42828172 | Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice |
Q40874476 | Decreased UV sensitivity, mismatch repair activity and abnormal cell cycle checkpoints in skin cancer cell lines derived from UVB-irradiated XPA-deficient mice |
Q36711117 | Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation |
Q33868100 | Defective nucleotide excision repair in xpc mutant mice and its association with cancer predisposition |
Q74604701 | Defects in transcription coupled repair interfere with expression of p90(MDM2) in response to ultraviolet light |
Q34937383 | Defining the origins of Ras/p53-mediated squamous cell carcinoma |
Q33588367 | Demystified ... p53. |
Q35112453 | Deregulated expression of insulin-like growth factor 1 in prostate epithelium leads to neoplasia in transgenic mice |
Q34985953 | Dermatological aspects of angiogenesis |
Q39927633 | Detection of DNA by scraping the formalin-fixed paraffin-embedded tissue. |
Q46456704 | Detection of p53 gene mutations in oral squamous cell carcinomas of a black African population sample |
Q73559750 | Determination of sunscreen agents in cosmetic products by supercritical fluid extraction and high-performance liquid chromatography |
Q36039774 | Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis |
Q36176798 | Development and evaluation of sunscreen creams containing morin-encapsulated nanoparticles for enhanced UV radiation protection and antioxidant activity |
Q33997846 | Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress |
Q53356707 | Dietary grape-seed proanthocyanidin inhibition of ultraviolet B-induced immune suppression is associated with induction of IL-12. |
Q34459620 | Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo. |
Q42466676 | Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions |
Q28593341 | Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis |
Q42436644 | Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes |
Q26745755 | Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? |
Q38924006 | Drug-induced photosensitivity: new insights into pathomechanisms and clinical variation through basic and applied science |
Q46736501 | E2F1 suppresses skin carcinogenesis via the ARF-p53 pathway |
Q36348801 | Early cancers of the skin: clinical, histopathological, and molecular characteristics |
Q33616030 | Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells |
Q37052187 | Effect of caffeine on UVB-induced carcinogenesis, apoptosis, and the elimination of UVB-induced patches of p53 mutant epidermal cells in SKH-1 mice |
Q36925208 | Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice. |
Q44149102 | Effect of nanoparticle encapsulation on the photostability of the sunscreen agent, 2-ethylhexyl-p-methoxycinnamate. |
Q28210848 | Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma Pigmentosum Study Group |
Q40457310 | Efficacy of a film-forming medical device containing sunscreen (50+) and piroxicam 0.8% in actinic keratosis and field cancerization: a multicenter, assessor-blinded, 3 month trial. |
Q39410687 | Emerging roles of transit-amplifying cells in tissue regeneration and cancer |
Q35092580 | Enhanced contact allergen- and UVB-induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1 |
Q39726376 | Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP. |
Q42499168 | Enhanced expression of retinoic acid-metabolizing enzyme CYP26A1 in sunlight-damaged human skin |
Q42944965 | Enhancement of ultraviolet B-induced skin tumor development in phospholipase Cε -knockout mice is associated with decreased cell death |
Q35105665 | Epidemiology of malignant melanoma |
Q33855465 | Epidermal differentiation, apoptosis, and senescence: common pathways? |
Q44571675 | Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes |
Q51212527 | Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization. |
Q91655661 | Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers |
Q37031372 | Erythema and ultraviolet indoor tanning: findings from a diary study |
Q33950229 | Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations |
Q30487052 | Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas. |
Q90438463 | Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes |
Q53516763 | Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12. |
Q74035529 | Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma |
Q53356436 | Fate of UVB-induced p53 mutations in SKH-hr1 mouse skin after discontinuation of irradiation: relationship to skin cancer development. |
Q33870775 | Flipping the oncogene switch: illumination of tumor maintenance and regression |
Q41005370 | Flow cytometric quantification of UV-induced cell death in a human squamous cell carcinoma-derived cell line: dose and kinetic studies. |
Q55435872 | Four-dimensional, dynamic mosaicism is a hallmark of normal human skin that permits mapping of the organization and patterning of human epidermis during terminal differentiation. |
Q35940911 | Frequent clones of p53-mutated keratinocytes in normal human skin |
Q35698913 | From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma |
Q42511176 | G2 phase cell cycle arrest in human skin following UV irradiation. |
Q34609350 | GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage. |
Q42453573 | Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation |
Q36992929 | Galectin-7 in the control of epidermal homeostasis after injury |
Q24670155 | Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes |
Q30454438 | Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches |
Q40975265 | Genetics of follicular thyroid cancer. |
Q34200712 | Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer |
Q40014685 | Gli2 upregulates cFlip and renders basal cell carcinoma cells resistant to death ligand-mediated apoptosis |
Q38258797 | Global contributions to the understanding of DNA repair and skin cancer |
Q24656612 | Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system |
Q34505029 | Green tea polyphenols: DNA photodamage and photoimmunology |
Q34801480 | Green tea prevents non-melanoma skin cancer by enhancing DNA repair |
Q28182155 | HLA-G in skin cancer: a wolf in sheep's clothing? |
Q40735762 | HPV-16 E6/7 immortalization sensitizes human keratinocytes to ultraviolet B by altering the pathway from caspase-8 to caspase-9-dependent apoptosis |
Q71810835 | Harvard report on cancer prevention. Causes of human cancer. Ultraviolet light |
Q35165702 | Have environmental mutagens caused oncomutations in people? |
Q42466835 | Health risks. |
Q40416597 | Health-related quality of life in adult dermatitis patients stratified by filaggrin genotype |
Q35560213 | Heat shock and UV-B-induced DNA damage and mutagenesis in skin |
Q34421860 | Heat shock proteins in the photobiology of human skin |
Q42482335 | High Prevalence of Mutations in the p53 Gene in Poorly Differentiated Squamous Cell Carcinomas in Xeroderma Pigmentosum Patients |
Q36338127 | High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum |
Q39867599 | High molecular weight hyaluronan decreases UVB-induced apoptosis and inflammation in human epithelial corneal cells. |
Q78036365 | Histopathological analysis of apoptosis, and expression of p53, bcl-2, bax, and Ki-67 in laryngeal squamous cell carcinomas and dysplasia |
Q36422379 | Hot-spot mutations in the p53 gene of liver nodules induced in rats fed DL-ethionine with a methyl-deficient diet |
Q37771907 | How sunlight causes melanoma |
Q36617473 | Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53 |
Q42802249 | Hydrogen peroxide is critical for UV-induced apoptosis inhibition. |
Q29618396 | Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours |
Q24609306 | Identification and characterization of tumor-initiating cells in human primary cutaneous squamous cell carcinoma |
Q39946627 | Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis |
Q33963409 | Imiquimod-induced TLR7 signaling enhances repair of DNA damage induced by ultraviolet light in bone marrow-derived cells |
Q44553500 | Immediate effects of UV radiation on the skin: modification by an antioxidant complex containing carotenoids |
Q71737400 | Immunohistochemical expression of p53 protein, mitotic index and nuclear morphometry in primary malignant melanoma of the skin |
Q34568136 | Immunotherapy for nonmelanoma skin cancer: does it have a future? |
Q42487983 | Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane. |
Q28752496 | Impact of climate change on skin cancer |
Q35756152 | In search of "stemness". |
Q53925387 | Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. |
Q35865937 | Increased activity of cell surface peptidases in HeLa cells undergoing UV-induced apoptosis is not mediated by caspase 3. |
Q73782280 | Increased apoptosis during papilloma development in mice susceptible to tumor progression |
Q61811232 | Increased expression of Fas on human epidermal cells after in vivo exposure to single-dose ultraviolet (UV) B or long-wave UVA radiation |
Q61527573 | Increased oxidative modification of albumin when illuminated in vitro in the presence of a common sunscreen ingredient: protection by nitroxide radicals |
Q57890991 | Increased proliferative activity and p53 expression in normal glandular breast tissue after radiation therapy |
Q34816028 | Independent contribution of three different pathways to ultraviolet-B-induced apoptosis |
Q77087984 | Individual variations in the correlation between erythemal threshold, UV-induced DNA damage and sun-burn cell formation |
Q34338550 | Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia |
Q42614297 | Induction of apoptosis by the transcription factor c-Jun |
Q40298208 | Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2. |
Q34166313 | Influence of hydroxypropyl-beta-cyclodextrin on photo-induced free radical production by the sunscreen agent, butyl-methoxydibenzoylmethane |
Q53184438 | Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches. |
Q39855397 | Ingenol mebutate in the treatment of 'Hydroxyurea-induced Squamous Dysplasia': a single centre experience |
Q40292865 | Inhibition of UVA-induced c-Jun N-terminal kinase activity results in caspase-dependent apoptosis in human keratinocytes |
Q42450437 | Inhibition of cutaneous ultraviolet light B–mediated inflammation and tumor formation with topical celecoxib treatment |
Q36678103 | Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention |
Q33361280 | Inhibitory effects of Baicalin on ultraviolet B-induced photo-damage in keratinocyte cell line |
Q33643327 | Insights into cancer from transgenic mouse models |
Q100559171 | Integrative transcriptomic analysis for linking acute stress responses to squamous cell carcinoma development |
Q36148890 | Interleukin-12 and photocarcinogenesis |
Q62073578 | Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair |
Q36737891 | Involvement of activation-induced cytidine deaminase in skin cancer development |
Q43215574 | Involvement of fas/fas ligand in ultraviolet B-induced apoptosis of murine peritoneal macrophages. |
Q35984429 | Italian expert consensus for the management of actinic keratosis in immunocompetent patients |
Q36371190 | Keratinocyte apoptosis in epidermal development and disease |
Q81820580 | Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis |
Q36269037 | Langerhans Cells Facilitate UVB-Induced Epidermal Carcinogenesis |
Q73713207 | Large accumulation of mRNA and DNA point modifications in a plant senescent tissue |
Q38956592 | Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity |
Q38563753 | Lessons from the p53 mutant mouse |
Q33716728 | Light, including ultraviolet |
Q37993122 | Liposomes in cosmeceutics |
Q73268471 | Localization of a non-melanoma skin cancer susceptibility region within the major histocompatibility complex by association analysis using microsatellite markers |
Q35274756 | Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes |
Q35829735 | Loss of Fas-ligand expression in mouse keratinocytes during UV carcinogenesis |
Q35002203 | Loss of epithelial p53 and αv integrin cooperate through Akt to induce squamous cell carcinoma yet prevent remodeling of the tumor microenvironment |
Q39991093 | Loss of heterozygosity analysis of keratoacanthoma reveals multiple differences from cutaneous squamous cell carcinoma |
Q77994277 | Loss of heterozygosity in actinic keratosis, squamous cell carcinoma and sun-exposed normal-appearing skin in Japanese: difference between Japanese and Caucasians |
Q54348263 | Loss of retinoblastoma protein, but not p53, is associated with the presence of papillomaviral DNA in feline viral plaques, Bowenoid in situ carcinomas, and squamous cell carcinomas. |
Q33728014 | Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis |
Q52926200 | Low prevalence of p53, p16(INK4a) and Ha-ras tumour-specific mutations in low-graded actinic keratosis. |
Q73966004 | Low-dose ultraviolet B radiation synergizes with TNF-alpha to induce apoptosis of keratinocytes |
Q37433589 | Low-fat diet and skin cancer risk: the women's health initiative randomized controlled dietary modification trial |
Q34489720 | MDM2 induces hyperplasia and premalignant lesions when expressed in the basal layer of the epidermis. |
Q36205384 | Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling. |
Q35579214 | Management of actic keratoses |
Q46226748 | Managing actinic keratoses with retinoids |
Q39911680 | Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation |
Q43116504 | Measurement of tumor-associated mutations in the nasal mucosa of rats exposed to varying doses of formaldehyde. |
Q34653887 | Mechanisms of UV-induced signal transduction |
Q34429488 | Mechanisms of photodamage of the skin and its functional consequences for skin ageing |
Q37589420 | Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin |
Q36742011 | Melanocyte biology and skin pigmentation |
Q33706941 | Melanoma and sun exposure: where are we now? |
Q64953093 | MicroRNA Dysregulation in Cutaneous Squamous Cell Carcinoma. |
Q35622876 | Microenvironmental regulation of the initiated cell |
Q38118880 | Milestones in photocarcinogenesis |
Q35055502 | Mitogen-activated protein kinase activation in UV-induced signal transduction |
Q36790264 | Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy |
Q41140205 | Molecular and cellular biomarkers for field cancerization and multistep process in head and neck tumorigenesis |
Q36548086 | Molecular biology of malignant melanoma and other cutaneous tumors. |
Q33533997 | Molecular epidemiology of human cancer |
Q33643298 | Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer |
Q44595003 | Molecular events associated with apoptosis and proliferation induced by ultraviolet-B radiation in the skin of hairless mice |
Q41262814 | Molecular genetic approaches to non-melanoma and melanoma skin cancer |
Q38966698 | Molecular signaling cascades involved in nonmelanoma skin carcinogenesis |
Q35765255 | Monoclonal origin of vulvar intraepithelial neoplasia and some vulvar hyperplasias |
Q30835452 | More epidermal p53 patches adjacent to skin carcinomas in renal transplant recipients than in immunocompetent patients: the role of azathioprine |
Q37061756 | Mouse Genetic Models Reveal Surprising Functions of IkB Kinase Alpha in Skin Development and Skin Carcinogenesis |
Q34001196 | Mouse models for the p53 R72P polymorphism mimic human phenotypes |
Q40942186 | Multiparameter fluorescence imaging microscopy: reagents and instruments |
Q40991506 | Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes |
Q74825193 | Murine tumor suppressor models |
Q41592432 | Mutagenesis in the P53 gene |
Q54405180 | Mutant p53 subverts p63 control over KLF4 expression in keratinocytes. |
Q78371271 | Mutation induction with UVB in mouse skin epidermis is suppressed in acute high-dose exposure |
Q42468263 | Mutation spectra of epidermal p53 clones adjacent to basal cell carcinoma and squamous cell carcinoma |
Q38232170 | Mutation, clonal fitness and field change in epithelial carcinogenesis. |
Q36620304 | Mutational spectrum of p53 gene in arsenic-related skin cancers from the blackfoot disease endemic area of Taiwan |
Q70996727 | Mutations in ras oncogenes: rare events in ultraviolet B radiation-induced mouse skin tumorigenesis |
Q38315709 | Natural products as photoprotection |
Q39463400 | Near-visible ultraviolet light induces a novel ubiquitous calcium-permeable cation current in mammalian cell lines. |
Q56828372 | Neoplasms |
Q33818052 | New approaches to understanding p53 gene tumor mutation spectra |
Q49167667 | Nipple connective tissue and its development: insights from the K14-PTHrP mouse |
Q34234165 | No longer a molecular black box--new clues to apoptosis and drug resistance in melanoma |
Q41141059 | Non-ionising UV light increases the optical density of hygroscopic self assembled DNA crystal films. |
Q42474290 | Non-melanoma Skin Cancer in Canada Chapter 2: Primary Prevention of Non-melanoma Skin Cancer. |
Q37499962 | Novel vitamin D compounds and skin cancer prevention |
Q24644671 | Nuclear and cell membrane effects contribute independently to the induction of apoptosis in human cells exposed to UVB radiation |
Q41679282 | Nuclear and non-nuclear targets of genotoxic agents in the induction of gene expression. Shared principles in yeast, rodents, man and plants |
Q49388294 | Ocular squamous cell carcinoma in Holstein cows from the South of Brazil |
Q77333665 | On the origins of tumor mutations in cancer genes: insights from the p53 gene |
Q41231312 | Oncogenes and tumor suppressor genes in photocarcinogenesis |
Q33759655 | Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice |
Q92610926 | Outcompeting cancer |
Q43966862 | P16(INK4A) is implicated in both the immediate and adaptative response of human keratinocytes to UVB irradiation |
Q41679881 | P53 expression in altered limbal basal cells of pingueculae, pterygia, and limbal tumors |
Q36216684 | P53 in cancer: a paradigm for modern management of cancer |
Q74671595 | P53-dependent and -independent links between DNA-damage, apoptosis and mutation frequency in ES cells |
Q37480043 | PKCepsilon overexpression, irrespective of genetic background, sensitizes skin to UVR-induced development of squamous-cell carcinomas |
Q38537351 | PLCε signaling in cancer |
Q36944052 | PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients. |
Q74769526 | Papillomaviruses: death-defying acts in skin cancer |
Q36390329 | Pathways involved in sunburn cell formation: deregulation in skin cancer |
Q47600992 | Pathways of tumor development and progression in drug-induced nonmelanoma skin cancer: a new hope or the next great confusion? |
Q41129880 | Pentoxifylline reduces the formation of sunburn cells |
Q30728582 | Persistent p53 mutations in single cells from normal human skin |
Q39201841 | Pharmacological doses of melatonin induce alterations in mitochondrial mass and potential, bcl-2 levels and K+ currents in UVB-exposed U937 cells. |
Q33249898 | Photobiological information obtained from XPA gene-deficient mice |
Q41596015 | Photocarcinogenesis: an overview |
Q37803249 | Photodamage to human skin by suberythemal exposure to solar ultraviolet radiation can be attenuated by sunscreens: a review |
Q34244830 | Photodynamic therapy for skin field cancerization: an international consensus. International Society for Photodynamic Therapy in Dermatology |
Q42523570 | Photoexposition discriminates Notch 1 expression in human cutaneous squamous cell carcinoma. |
Q37052183 | Photoprotection in human skin--a multifaceted SOS response |
Q46099479 | Photoprotective effect of Pothomorphe umbellata on UVB radiation-induced biomarkers involved in carcinogenesis of hairless mouse epidermis |
Q37081694 | Phytochemicals for prevention of solar ultraviolet radiation-induced damages |
Q42111415 | Polo-like kinase 1 (Plk1) in non-melanoma skin cancers |
Q41071727 | Poly(ADP-ribosyl)ation as a fail-safe, transcription-independent, suicide mechanism in acutely DNA-damaged cells: a hypothesis |
Q28370435 | Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea reduces UVB-induced inflammatory responses and infiltration of leukocytes in human skin |
Q36937157 | Preneoplastic lesion growth driven by the death of adjacent normal stem cells |
Q36587639 | Preventative topical diclofenac treatment differentially decreases tumor burden in male and female Skh-1 mice in a model of UVB-induced cutaneous squamous cell carcinoma |
Q35610059 | Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling |
Q34964324 | Proanthocyanidins from grape seeds inhibit UV-radiation-induced immune suppression in mice: detection and analysis of molecular and cellular targets |
Q77530519 | Progression of actinic keratosis to squamous cell carcinoma of the skin correlates with deletion of the 9p21 region encoding the p16(INK4a) tumor suppressor |
Q35079913 | Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes |
Q32186628 | Propolis Inhibits UVA-Induced Apoptosis of Human Keratinocyte HaCaT Cells by Scavenging ROS. |
Q35171016 | Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase |
Q41322218 | Protective Effect of Chitin Urocanate Nanofibers against Ultraviolet Radiation |
Q34418244 | Protective actions of vitamin D in UVB induced skin cancer |
Q33251893 | Protective effect of the isoflavone equol against DNA damage induced by ultraviolet radiation to hairless mouse skin |
Q34443888 | Protective role of vitamin D signaling in skin cancer formation |
Q92446071 | Protein Oxidative Damage in UV-Related Skin Cancer and Dysplastic Lesions Contributes to Neoplastic Promotion and Progression |
Q33786961 | Protein kinase Cepsilon inhibits UVR-induced expression of FADD, an adaptor protein, linked to both Fas- and TNFR1-mediated apoptosis. |
Q38312316 | Pyrimidine (6-4) pyrimidone photoproduct mapping after sublethal UVC doses: nucleotide resolution using terminal transferase-dependent PCR. |
Q33798257 | Rad52 deficiency decreases development of lung squamous cell carcinomas by enhancing immuno-surveillance |
Q55185800 | Recent advances in field cancerization and management of multiple cutaneous squamous cell carcinomas. |
Q27024320 | Reconstructing skin cancers using animal models |
Q35073475 | Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma. |
Q37054352 | Reduced P53 Staining in Actinic Keratosis is Associated with Squamous Cell Carcinoma: A Preliminary Study |
Q33816459 | Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis |
Q27730292 | Refined solution structure of the oligomerization domain of the tumour suppressor p53 |
Q38287796 | Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes |
Q42474867 | Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation. |
Q34786185 | Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis |
Q35782064 | Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma |
Q42509362 | Repeated exposures of human skin equivalent to low doses of ultraviolet-B radiation lead to changes in cellular functions and accumulation of cyclobutane pyrimidine dimers |
Q36861158 | Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis |
Q35103129 | Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis |
Q44635839 | Resistance to UV‐induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53 |
Q28535277 | Resveratrol couples apoptosis with autophagy in UVB-irradiated HaCaT cells |
Q43612561 | Rethinking the role of tumour necrosis factor-alpha in ultraviolet (UV) B-induced immunosuppression: altered immune response in UV-irradiated TNFR1R2 gene-targeted mutant mice. |
Q33826576 | Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases. |
Q92733745 | Riboflavin Plays a Pivotal Role in the UVA-Induced Cytotoxicity of Fibroblasts as a Key Molecule in the Production of H2O2 by UVA Radiation in Collaboration with Amino Acids and Vitamins |
Q42321243 | Ribosomal stress, p53 activation and the tanning response |
Q41773184 | Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light |
Q28277703 | Role of Apaf-1, a key regulator of apoptosis, in melanoma progression and chemoresistance |
Q40445624 | Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins |
Q37822741 | Role of IKKα in skin squamous cell carcinomas |
Q41515342 | Role of p53 in apoptosis. |
Q40209179 | Selenomethionine inhibits ultraviolet radiation-induced p53 transactivation |
Q49980732 | Sensitive Synchronous Spectrofluorimetric Study of Certain Sunscreens Using Fluorescence Enhancers in Cosmeceutical Formulations. |
Q36415130 | Sensitivity of rice to ultraviolet-B radiation |
Q33598827 | Signal transduction and transcription factors in rheumatic disease |
Q36226855 | Signal transduction pathways in cancer development and as targets for cancer prevention |
Q37453180 | Signature p53 mutation at DNA cross-linking sites in 8-methoxypsoralen and ultraviolet A (PUVA)-induced murine skin cancers |
Q42496514 | Skin cancer after nonmyeloablative hematopoietic cell transplantation |
Q24655517 | Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms |
Q37670765 | Socializing with MYC: cell competition in development and as a model for premalignant cancer |
Q53209256 | Somatic mosaicism: on the road to cancer. |
Q41430340 | Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations |
Q36600496 | Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. |
Q74608875 | Spontaneous and ultraviolet light-induced direct repeat recombination in mammalian cells frequently results in repeat deletion |
Q89811259 | Squamous differentiation requires G2/mitosis slippage to avoid apoptosis |
Q37480072 | Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53. |
Q33591760 | Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia |
Q36326004 | Strand asymmetry of CpG transitions as indicator of G1 phase-dependent origin of multiple tumorigenic p53 mutations in stem cells |
Q41229276 | Stress proteins in the cellular response to ultraviolet radiation |
Q58553854 | Sublethal UV irradiation induces squamous differentiation via a p53-independent, DNA damage-mitosis checkpoint |
Q57494790 | Successful development of squamous cell carcinoma and hyperplasia in RGEN-mediated p27 KO mice after the treatment of DMBA and TPA |
Q43612584 | Successful treatment of actinic keratosis with imiquimod cream 5%: a report of six cases |
Q42439781 | Sulfur Mustard-Induced Apoptosis in Hairless Guinea Pig Skin |
Q41102161 | Sun exposure, sunscreens, and skin cancer prevention: a year-round concern |
Q60077706 | Sun protection factor p53 |
Q42453517 | Sunlight and carcinogenesis: expression of p53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiations |
Q36001068 | Sunlight and skin cancer: another link revealed |
Q73321284 | Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens |
Q41627449 | Sunlight and the onset of skin cancer |
Q38563566 | Supercompetitor status of Drosophila Myc cells requires p53 as a fitness sensor to reprogram metabolism and promote viability |
Q41097570 | Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT. |
Q37522406 | Sweat gland progenitors in development, homeostasis, and wound repair |
Q47231411 | Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size |
Q38187197 | Synergism between mTOR pathway and ultraviolet radiation in the pathogenesis of squamous cell carcinoma and its implication for solid-organ transplant recipients |
Q53449284 | Synergistic interactions between XPC and p53 mutations in double-mutant mice: neural tube abnormalities and accelerated UV radiation-induced skin cancer. |
Q46585802 | Synthesis of mono-dispersed spherical silica particles containing covalently bonded chromophores |
Q31809899 | Synthetic retinoid CD437 promotes rapid apoptosis in malignant human epidermal keratinocytes and G1 arrest in their normal counterparts |
Q40317235 | TAp63alpha indirectly regulates a cutaneous HPV promoter through complex formation with Jun family members |
Q35078728 | TP53 mutations in human skin cancers. |
Q36673593 | TP53 mutations in vulval lichen sclerosus adjacent to squamous cell carcinoma of the vulva |
Q34436456 | Targeting tumor necrosis factor alpha. New drugs used to modulate inflammatory diseases |
Q35597618 | Telomerase as a novel and potentially selective target for cancer chemotherapy |
Q35275682 | Temporal dissection of tumorigenesis in primary cancers |
Q35793451 | Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin |
Q44655514 | Thalidomide inhibits UVB‐induced mouse keratinocyte apoptosis by both TNF‐α‐dependent and TNF‐α‐independent pathways |
Q36134953 | The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene |
Q34784078 | The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations |
Q53557742 | The c-Rel subunit of NF-κB is a crucial regulator of phenotype and motility of HaCaT keratinocytes. |
Q43194398 | The circadian clock controls sunburn apoptosis and erythema in mouse skin |
Q30868560 | The consequences for human health of stratospheric ozone depletion in association with other environmental factors |
Q42457949 | The density of epidermal p53 clones is higher adjacent to squamous cell carcinoma in comparison with basal cell carcinoma. |
Q34418017 | The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21. |
Q83204740 | The effects of gp100 and tyrosinase peptide vaccinations on nevi in melanoma patients |
Q46189468 | The essential role of p53 in hyperpigmentation of the skin via regulation of paracrine melanogenic cytokine receptor signaling |
Q100491078 | The genomic landscapes of individual melanocytes from human skin |
Q47098228 | The interplay of UV and cutaneous papillomavirus infection in skin cancer development |
Q37087448 | The melanocortin 1 receptor and the UV response of human melanocytes--a shift in paradigm |
Q73942607 | The molecular determinants of sunburn cell formation |
Q41438677 | The natural somatic mutation frequency and human carcinogenesis. |
Q38548852 | The p53 tumour suppressor gene |
Q38759912 | The photoprotective effects of 2-benzoyl-3-phenylquinoxaline 1,4-dioxide against UVB-induced damage in HaCaT cells |
Q40825707 | The phototumorigenic fluoroquinolone, lomefloxacin, photosensitises p53 accumulation and transcriptional activity in human skin cells |
Q38918002 | The presence of antibodies against virus-like particles of epidermodysplasia verruciformis-associated humanpapillomavirus type 8 in patients with actinic keratoses |
Q51725084 | The preventive effect of linalool on acute and chronic UVB-mediated skin carcinogenesis in Swiss albino mice. |
Q40374507 | The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas |
Q24656870 | The protective role of melanin against UV damage in human skin |
Q35033717 | The protective role of vitamin d signaling in non-melanoma skin cancer |
Q33685413 | The regulation of the p53-mediated stress response by MDM2 and MDM4. |
Q38124247 | The role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescence |
Q41193565 | The role of DNA repair in the prevention of cancer |
Q24626306 | The role of altered nucleotide excision repair and UVB-induced DNA damage in melanomagenesis |
Q38153719 | The role of genetics in the pathogenesis of periocular cutaneous neoplasms: implications for targeted therapy. |
Q35142669 | The role of p53 in the immunobiology of cutaneous squamous cell carcinoma |
Q36379372 | The small-molecule immune response modifier imiquimod--its mode of action and clinical use in the treatment of skin cancer |
Q39108767 | The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas. |
Q35773569 | The two faces of tumor suppressor p53 |
Q33806485 | The vitamin D receptor: a tumor suppressor in skin. |
Q61988950 | The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts |
Q36703886 | Topical diclofenac in the treatment of actinic keratoses |
Q35196261 | Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas |
Q41703686 | Toward the biologic treatment of nonmelanoma skin cancer |
Q49010279 | Towards elucidating the photochemistry of the sunscreen filter ethyl ferulate using time-resolved gas-phase spectroscopy |
Q36042009 | Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53 |
Q52901124 | Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis. |
Q56516436 | Treatment of Grade II and III Actinic Keratosis Lesions with a Film-Forming Medical Device Containing Sunscreen/Piroxicam 0.8% and a Retinoic Acid/Glycolic Gel: A Pilot Trial |
Q35752935 | Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin |
Q41231324 | Tumor suppressor gene mutations and photocarcinogenesis |
Q34447387 | Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment. |
Q42445719 | Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod |
Q35787577 | Tumorigenic conversion of immortal human keratinocytes through stromal cell activation |
Q96022920 | Tumour predisposition and cancer syndromes as models to study gene-environment interactions |
Q33807787 | Twenty years of p53 research: structural and functional aspects of the p53 protein |
Q37281082 | UV and pigmentation: molecular mechanisms and social controversies |
Q77361503 | UV light affects cell membrane and cytoplasmic targets |
Q34963798 | UV signature mutations |
Q35163378 | UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cells |
Q53411206 | UV-induced DNA damage in carcinogenesis and its repair. |
Q42500149 | UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis |
Q36016758 | UV-induced immune suppression and photocarcinogenesis: chemoprevention by dietary botanical agents |
Q77910521 | UV-induced mutations and skin cancer: how important is the link? |
Q35160357 | UV-induced skin damage |
Q42453572 | UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma |
Q24656167 | UVB-induced apoptosis drives clonal expansion during skin tumor development |
Q39969912 | UVB-induced murine bone marrow derived macrophages and apoptosis |
Q73268122 | UVB-induced mutagenesis in hairless lambda lacZ-transgenic mice |
Q37501797 | UVB-induced skin inflammation and cutaneous tissue injury is dependent on the MHC class I-like protein, CD1d |
Q40528894 | Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region |
Q36989955 | Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis |
Q53756271 | Ultraviolet B-Sensitive Rice Cultivar Deficient in Cyclobutyl Pyrimidine Dimer Repair. |
Q35933915 | Ultraviolet C irradiation induces different expression of cyclooxygenase 2 in NIH 3T3 cells and A431 cells: the roles of COX-2 are different in various cell lines |
Q38480106 | Ultraviolet Light Induces Expression of p53 and p21 in Human Skin: Effect of Sunscreen and Constitutive p21 Expression in Skin Appendages |
Q42504727 | Ultraviolet Radiation-Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma |
Q50074973 | Ultraviolet Radiations: Skin Defense-Damage Mechanism |
Q40668456 | Ultraviolet irradiation increases FADD protein in apoptotic human keratinocytes |
Q51372405 | Ultraviolet light (UVB and UVA) induces the damage-responsive transcription factor CHOP/gadd153 in murine and human epidermis: evidence for a mechanism specific to intact skin. |
Q32152397 | Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L |
Q35146567 | Ultraviolet radiation and cutaneous malignant melanoma |
Q36034693 | Ultraviolet radiation and skin cancer: molecular mechanisms |
Q36117765 | Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa. |
Q73626853 | Ultraviolet radiation-induced interleukin 6 release in HeLa cells is mediated via membrane events in a DNA damage-independent way |
Q33669664 | Ultraviolet radiation-induced p53 responses in the epidermis are differentiation-dependent |
Q35146557 | Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer |
Q60585123 | Urinary thymine dimers and 8-oxo-2′-deoxyguanosine in psoriasis |
Q30847975 | Use of mutant mice in photoimmunological and photocarcinogenic investigations |
Q33527015 | Vitamin D and the skin |
Q33993788 | Vitamin D and the skin: Physiology and pathophysiology |
Q42441596 | Vitamin D receptor, UVR, and skin cancer: a potential protective mechanism |
Q38307555 | Vitamin D receptor, a tumor suppressor in skin |
Q36130042 | Vitamin D-insufficiency: An estimate of the situation in Germany |
Q42461302 | Vulvar lichen sclerosus and squamous cell carcinoma: a cohort, case control, and investigational study with historical perspective; implications for chronic inflammation and sclerosis in the development of neoplasia. |
Q92177507 | Whole Fruit Phytochemicals Combating Skin Damage and Carcinogenesis |
Q59040377 | Wrinkles waiting for GOD0T |
Q73095006 | Zinc and DNA fragmentation in keratinocyte apoptosis: its inhibitory effect in UVB irradiated cells |
Q40142019 | [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo |
Q73665883 | [Actinic keratoses] |
Q53652028 | [Sun protection during holidays]. |
Q40486926 | alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage |
Q28510655 | deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes |
Q31166675 | miR-365 promotes cutaneous squamous cell carcinoma (CSCC) through targeting nuclear factor I/B (NFIB) |
Q100958819 | p21CIP1 controls the squamous differentiation response to replication stress |
Q42437929 | p21WAF1/CIP1 expression in non-melanoma skin tumors |
Q53856246 | p51/p63 Inhibits ultraviolet B-induced apoptosis via Akt activation. |
Q34377287 | p53 Family and Cellular Stress Responses in Cancer |
Q38451611 | p53 alterations in porokeratosis |
Q43970148 | p53 and Fas ligand are required for psoralen and UVA-induced apoptosis in mouse epidermal cells |
Q40855467 | p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV. |
Q36149069 | p53 and the pathogenesis of skin cancer |
Q28585207 | p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein |
Q33988669 | p53 deficiency does not affect the accumulation of point mutations in a transgene target |
Q44582665 | p53 expression and risk factors for cutaneous melanoma: a case-control study. |
Q42465138 | p53 expression in skin carcinogenesis and its relationship to cell proliferation and tumour growth |
Q73313733 | p53 gene mutation analysis in porokeratosis and porokeratosis-associated squamous cell carcinoma |
Q34585815 | p53 gene mutation: software and database. |
Q40370722 | p53 gene mutations and photocarcinogenesis |
Q45047040 | p53 gene mutations in Bowen's disease in Koreans: clustering in exon 5 and multiple mutations |
Q81571661 | p53 is required for spontaneous autoantibody production in B6/lpr lupus mice |
Q33750337 | p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer |
Q37311820 | p53 mutations as fingerprints for aristolochic acid: an environmental carcinogen in endemic (Balkan) nephropathy |
Q47751814 | p53 mutations in cutaneous lesions induced in the hairless mouse by a solar ultraviolet light simulator |
Q41838620 | p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis |
Q53450210 | p53 mutations in solar keratoses. |
Q53420584 | p53 protects against skin cancer induction by UV-B radiation. |
Q57082909 | p53 protein and the response of human skin to UV |
Q37049524 | p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer |
Q27860990 | p53, the cellular gatekeeper for growth and division |
Q41715281 | p53--an acrobat in tumorigenesis |
Q71046591 | p53-dependent apoptosis suppresses radiation-induced teratogenesis |
Q47793225 | p53-dependent regulation of nucleotide excision repair in murine epidermis in vivo |
Q36042648 | p53-mediated protective responses to UV irradiation. |
Q42459993 | p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes |
Q41284102 | p53: guardian of cellular senescence |
Q92322221 | Épidémiologie des kératoses actiniques: Epidemiology of actinic keratosis |
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