DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance

scientific article published on 29 January 2008

DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1111/J.1751-1097.2007.00284.X
P932PMC publication ID2718731
P698PubMed publication ID18248501
P5875ResearchGate publication ID5602883

P50authorSantosh K KatiyarQ90226138
Laura TimaresQ95967443
Craig A. ElmetsQ110142695
P2860cites workBmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikisQ24291662
p53 has a direct apoptogenic role at the mitochondriaQ24298888
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell functionQ24558690
UVB-induced apoptosis drives clonal expansion during skin tumor developmentQ24656167
Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancerQ24672079
Functional activity of serotoninergic and melatoninergic systems expressed in the skinQ28206451
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissuesQ28214619
Cell death: critical control pointsQ28240722
Complicating the complexity of p53Q28250110
To die or not to die: how does p53 decide?Q28255819
Langerhans cells arise from monocytes in vivoQ28294423
Overview of ultraviolet radiation and cancer: what is the link? How are we doing?Q28389677
Cancer statistics, 2007Q29547293
Live or let die: the cell's response to p53Q29547663
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesisQ29615762
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathwayQ29616436
The dendritic cell system and its role in immunogenicityQ29619870
Use of mutant mice in photoimmunological and photocarcinogenic investigationsQ30847975
Association of transcription-coupled repair but not global genome repair with ultraviolet-B-induced Langerhans cell depletion and local immunosuppression.Q31027964
Changes in biologically-active ultraviolet radiation reaching the Earth's surfaceQ31104679
Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis.Q42503542
Epidermal langerhans cell depletion after artificial ultraviolet B irradiation of human skin in vivo: apoptosis versus migrationQ42520767
Prevention of UV radiation-induced immunosuppression by IL-12 is dependent on DNA repairQ31142218
Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and agingQ32062951
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95LQ32152397
In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cellsQ33196662
Ultraviolet light and dendritic cells.Q33651376
A blast from the past: clearance of apoptotic cells regulates immune responses.Q34162195
Xeroderma pigmentosum. Cutaneous, ocular, and neurologic abnormalities in 830 published casesQ34183159
Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cellsQ34265522
Mouse models of cell deathQ34266817
Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet lightQ34292522
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.Q34312488
A review of studies on the effects of ultraviolet irradiation on the resistance to infections: evidence from rodent infection models and verification by experimental and observational human studies.Q34506469
Differential expression and function of Toll-like receptors in Langerhans cells: comparison with splenic dendritic cellsQ34545600
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.Q34563627
C-type lectin receptors on dendritic cells and Langerhans cellsQ34575346
Langerhans cells cross-present antigen derived from skinQ34650867
Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunizationQ34801021
Sources and measurement of ultraviolet radiationQ34857731
Expression of Bcl-2 family member Bid in normal and malignant tissuesQ34997430
Molecular determinants of UV-induced immunosuppressionQ35005685
Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesisQ35020151
Revisiting the photochemistry of solar UVA in human skinQ35025236
UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine-thymine dipyrimidines and correlate with the mutation spectrum in rodent cellsQ35032228
Progress in cutaneous cancer researchQ35041463
Life and death signaling pathways contributing to skin cancerQ35041469
Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T cells inhibiting allograft rejection and autoimmune diseases.Q35042170
Biology of the TRANCE axisQ35145622
Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancerQ35157905
Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptorQ35768659
Overexpression of Bcl-2 protects from ultraviolet B-induced apoptosis but promotes hair follicle regression and chemotherapy-induced alopeciaQ35809922
Changing paradigms in cutaneous immunology: adapting with dendritic cellsQ36011852
Ultraviolet radiation and skin cancer: molecular mechanismsQ36034693
Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53Q36042009
Skin cancerQ71731138
Role of tumour necrosis factor-alpha in ultraviolet B light-induced dendritic cell migration and suppression of contact hypersensitivityQ72302285
Susceptibility to immunosuppression by ultraviolet B radiation in the mouseQ72568084
The effect of chronic treatment of mice with urocanic acid isomersQ73347143
Ultraviolet light-induced immune tolerance is mediated via the Fas/Fas-ligand systemQ74515343
Mechanisms underlying the suppression of established immune responses by ultraviolet radiationQ74786008
Regulation of mucosal dendritic cell function by receptor activator of NF-kappa B (RANK)/RANK ligand interactions: impact on tolerance inductionQ74817249
Mechanisms involved in ultraviolet light-induced immunosuppressionQ75255580
N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skinQ77519474
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
A JNK-Dependent Pathway Is Required for TNFα-Induced ApoptosisQ79129693
Upgrading the BCL-2 networkQ79397659
The JNK signal transduction pathwayQ79781771
Migratory dendritic cells: sometimes simply ferries?Q79965280
IL-10 controls ultraviolet-induced carcinogenesis in miceQ80500065
TRANCE counteracts FasL-mediated apoptosis of murine bone marrow-derived dendritic cellsQ81789743
Regulatory T cellsQ82281684
The UVB-induced gene expression profile of human epidermis in vivo is different from that of cultured keratinocytesQ82363604
Tolerance induction by transcutaneous immunization through ultraviolet-irradiated skin is transferable through CD4+CD25+ T regulatory cells and is dependent on host-derived IL-10Q82459218
Enhanced photocarcinogenesis in interleukin-12-deficient miceQ82843695
Relationship between p53 codon 72 polymorphism and susceptibility to sunburn and skin cancerQ42524556
Rethinking the role of tumour necrosis factor-alpha in ultraviolet (UV) B-induced immunosuppression: altered immune response in UV-irradiated TNFR1R2 gene-targeted mutant mice.Q43612561
Influence of ultraviolet B exposure on immune responses following hepatitis B vaccination in human volunteersQ43800839
Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacityQ44240882
1,25-Dihydroxyvitamin D3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytesQ44511478
Vitamin D3 supports osteoclastogenesis via functional vitamin D response element of human RANKL gene promoterQ44511491
Involvement of Dectin-2 in Ultraviolet Radiation-Induced ToleranceQ44590792
UVB-irradiated dendritic cells fail to tolerize murine CD8 naïve or effector T cellsQ44854469
The serotoninergic receptors of human dendritic cells: identification and coupling to cytokine releaseQ44885056
Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosisQ44891566
Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells.Q45112689
Proapoptotic BID is an ATM effector in the DNA-damage responseQ46669145
Mice with genetically determined high susceptibility to ultraviolet (UV)-induced immunosuppression show enhanced UV carcinogenesisQ47281831
No association between p53 codon 72 polymorphisms and erythemal responseQ47613026
Specificity in stress response: epidermal keratinocytes exhibit specialized UV-responsive signal transduction pathwaysQ48148106
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.Q50768287
A prospective study of pigmentation, sun exposure, and risk of cutaneous malignant melanoma in women.Q51812350
Impaired NK1+ T cell development and early IL-4 production in CD1-deficient mice.Q52525223
Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production.Q52547955
Interleukin-12-deficient mice are at greater risk of UV radiation-induced skin tumors and malignant transformation of papillomas to carcinomas.Q53346766
Inverse relationship between increased apoptosis and decreased skin cancer in UV-irradiated CD1d-/- mice.Q53363953
Immune suppression and skin cancer development: regulation by NKT cells.Q53400482
p53 protects against skin cancer induction by UV-B radiation.Q53420584
Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.Q53421778
Mechanisms of depressed reactivity to dinitrochlorobenzene and ultraviolet-induced tumors during ultraviolet carcinogenesis in BALB/c miceQ53585988
Genetic variation in low-dose UV-induced suppression of contact hypersensitivity and in the skin photocarcinogenesis response.Q54151934
Characterization of the immunogenetic basis of ultraviolet-B light effects on contact hypersensitivity induction.Q54211759
Long-lived immature dendritic cells mediated by TRANCE-RANK interactionQ56966224
Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cellsQ57184743
The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle ArrestQ57272464
Dominant role of the niche in melanocyte stem-cell fate determinationQ57338437
Langerhans cells develop from a lymphoid-committed precursorQ58436643
Langerhans cells acquire a CD8+ dendritic cell phenotype on maturation by CD40 ligationQ58436648
Immunosuppressive effects of apoptotic cellsQ59060221
Sunburn and p53 in the onset of skin cancerQ59067136
Effects of solar simulated radiation on the human immune system: influence of phototypes and wavebandsQ59262243
Langerhans Cells Activate Naive Self-Antigen-Specific CD8 T Cells in the Steady StateQ60181710
Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repairQ62073578
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1Q62746016
DNA double strand breaks in epidermal cells cause immune suppression in vivo and cytokine production in vitroQ64389382
A comparison of murine epidermal Langerhans cells with spleen dendritic cellsQ67295627
The effect of ultraviolet B irradiation and urocanic acid isomers on dendritic cell migrationQ67982166
The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cellsQ68016811
N-ras mutation in ultraviolet radiation-induced murine skin cancersQ68182662
Alteration in murine epidermal Langerhans cell population by various UV irradiations: quantitative and morphologic studies on the effects of various wavelengths of monochromatic radiation on Ia-bearing cellsQ69832653
Transmission of human epidermis and stratum corneum as a function of thickness in the ultraviolet and visible wavelengthsQ70685620
Interleukin-12 prevents ultraviolet B-induced local immunosuppression and overcomes UVB-induced toleranceQ71383596
Rôle of DNA damage in local suppression of contact hypersensitivity in mice by UV radiationQ71612391
Induction of pyrimidine dimers in epidermal DNA of hairless mice by UVB: an action spectrumQ71668129
Transcription, apoptosis and p53: catch-22.Q36056198
Mechanisms underlying UV-induced immune suppressionQ36062334
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.Q36117765
Incidence of basal cell and squamous cell carcinomas in a population younger than 40 yearsQ36224045
Dendritic cell modulation by 1alpha,25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivoQ36236655
CD4 T cell-induced, bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responses.Q36303053
Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivityQ36321301
Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiationQ36348070
Localization of DNA damage and its role in altered antigen-presenting cell function in ultraviolet-irradiated miceQ36366535
A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiationQ36368071
Keratinocyte apoptosis in epidermal development and diseaseQ36371190
Sensitivity to sunburn is associated with susceptibility to ultraviolet radiation-induced suppression of cutaneous cell-mediated immunityQ36375903
TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivoQ36375923
Bid, a BH3-only multi-functional molecule, is at the cross road of life and deathQ36381619
Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotectionQ36390337
Dissecting p53-dependent apoptosis.Q36423933
Langerhans cells renew in the skin throughout life under steady-state conditionsQ36505129
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host diseaseQ36505142
Phagocytosis of apoptotic cells and immune regulationQ36511373
Epidermal Langerhans cells--changing views on their function in vivo.Q36530941
Cell type and DNA damage specific response of human skin cells to environmental agents.Q36552408
Role of Langerhans cells in cutaneous protective immunity: is the reappraisal necessary?Q36583963
The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored by in vitro photorepair of cyclobutane pyrimidine dimersQ36770600
Sunlight and skin cancer: lessons from the immune systemQ36795439
Photoimmunology--illuminating the immune system through photobiologyQ36875885
Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivityQ38317679
Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivityQ38480730
Effect of gene-targeted mutation in TNF receptor (p55) on contact hypersensitivity and ultraviolet B-induced immunosuppressionQ38508352
Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice.Q39645013
The induction of immunity to a protein antigen using an adjuvant is significantly compromised by ultraviolet A radiationQ40339508
The optics of human skinQ40353006
A role for proapoptotic BID in the DNA-damage responseQ40381562
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.Q40393322
Powerful skin cancer protection by a CPD-photolyase transgene.Q40466370
Ultraviolet-B radiation causes an upregulation of survivin in human keratinocytes and mouse skin.Q40476473
Further studies on the tumor-specific suppressor cells induced by ultraviolet radiationQ40688339
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signalingQ40878328
HindIII liposomes suppress delayed-type hypersensitivity responses in vivo and induce epidermal IL-10 in vitro.Q41007935
UV-DNA damage in mouse and human cells induces the expression of tumor necrosis factor alphaQ41030298
The similarity of action spectra for thymine dimers in human epidermis and erythema suggests that DNA is the chromophore for erythema.Q42465416
P433issue2
P921main subjectapoptotic processQ14599311
DNA damageQ5205747
P304page(s)422-436
P577publication date2008-01-29
P1433published inPhotochemistry and PhotobiologyQ3381560
P1476titleDNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance
P478volume84