Botulinum toxin type A blocks the morphological changes induced by chemical stimulation on the presynaptic membrane of Torpedo synaptosomes

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Botulinum toxin type A blocks the morphological changes induced by chemical stimulation on the presynaptic membrane of Torpedo synaptosomes is …
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scholarly articleQ13442814

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P819ADS bibcode1989PNAS...86..372M
P356DOI10.1073/PNAS.86.1.372
P932PMC publication ID286467
P698PubMed publication ID2463625
P5875ResearchGate publication ID20691760

P2093author name stringRabasseda X
Marsal J
Solsona C
Blasi J
Egea G
P2860cites workSynaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter releaseQ24682015
Brief occurrence of a population of presynaptic intramembrane particles coincides with transmission of a nerve impulseQ34590661
Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. III. A morphometric analysis of the number and diameter of intramembrane particlesQ36201453
Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. I. Effects of black widow spider venom and Ca2+-free solutions on the structure of the active zoneQ36203807
Isolation of pure cholinergic nerve endings from Torpedo electric organ. Evaluation of their metabolic propertiesQ36203913
Structural evidence that botulinum toxin blocks neuromuscular transmission by impairing the calcium influx that normally accompanies nerve depolarizationQ36204515
Structural changes after transmitter release at the frog neuromuscular junctionQ36208626
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranesQ37680475
Molecular pharmacology of botulinum toxin and tetanus toxinQ39735565
Improved procedure for crystallization of Clostridium botulinum type A toxic complexesQ39812425
Affinity chromatography purification of type A botulinum neurotoxin from crystalline toxic complexQ40075808
Action of brown widow spider venom and botulinum toxin on the frog neuromuscular junction examined with the freeze-fracture techniqueQ40124482
The release of acetylcholine: from a cellular towards a molecular mechanismQ41353185
Botulinum A toxin and tetanus toxin do not affect presynaptic membrane currents in mammalian motor nerve endingsQ41557214
Inhibition by botulinum toxin of depolarization-evoked release of (14C)acetylcholine from synaptosomes in vitroQ42535175
LACTATE DEHYDROGENASE AS A CYTOPLASMIC MARKER IN BRAIN.Q42958374
Release of ATP from a synaptosomal preparation by elevated extracellular K+ and by veratridineQ43513435
Calcium fluxes in isolated pure cholinergic nerve endings from the electric organ of Torpedo marmorata.Q52506825
Continuous determination by a chemiluminescent method of acetylcholine release and compartmentation in Torpedo electric organ synaptosomes.Q53863158
Depolarisation-Induced Release of ATP from Cortical Synaptosomes Is Not Associated with Acetylcholine ReleaseQ53961851
Botulinum toxin inhibits quantal acetylcholine release and energy metabolism in the Torpedo electric organ.Q54408650
Structural changes at pure cholinergic synaptosomes during the transmitter release induced by A-23187 inTorpedo marmorataQ58493609
Turnover of adenine nucleotides in cholinergic synaptic vesicles of the Torpedo electric organQ67409485
The effect of type D botulinum toxin on frog neuromuscular junctionsQ68630516
Increase in the number of presynaptic large intramembrane particles during synaptic transmission at the Torpedo nerve-electroplaque junctionQ70155129
Preparation and characterisation of homogeneous neurotoxin type A from Clostridium botulinum. Its inhibitory action on neuronal release of acetylcholine in the absence and presence of beta-bungarotoxinQ70218719
Redistribution of intramembrane particles related to acetylcholine release by cholinergic synaptosomesQ70880229
Ultrastructural changes and transmitter release induced by depolarization of cholinergic synaptosomes. A freeze-fracture study of a synaptosomal fraction from torpedo electric organQ71189322
Decrease of the spontaneous non-quantal release of acetylcholine from the phrenic nerve in botulinum-poisoned rat diaphragmQ71838616
Relationship between presynaptic membrane potential and acetylcholine release in synaptosomes from Torpedo electric organQ72745996
The cholinergic nature of the nerves to the electric organ of the Torpedo (Torpedo marmorata)Q80316250
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbotulinum toxin type AQ4095199
P304page(s)372-376
P577publication date1989-01-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleBotulinum toxin type A blocks the morphological changes induced by chemical stimulation on the presynaptic membrane of Torpedo synaptosomes
P478volume86

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cites work (P2860)
Q92210136Acute Functional Adaptations in Isolated Presynaptic Terminals Unveil Synaptosomal Learning and Memory
Q37954286Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells
Q58493594Binding of botulinum neurotoxin to pure cholinergic nerve terminals isolated from the electric organ of Torpedo
Q34351277Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein
Q34871028Control of neurotransmitter release by an internal gel matrix in synaptic vesicles
Q49013928Functional reconstitution of KCl-evoked, Ca(2+)-dependent acetylcholine release system in Xenopus oocytes microinjected with presynaptic plasma membranes and synaptic vesicles
Q58300696Phenotypic effect of botulinum toxin A onCaenorhabditis elegans
Q58493600Ultrastructural Changes Induced by 12-O-Tetradecanoylphorbol 13-Acetate in Pure Cholinergic Synaptosomes of Torpedo Electric Organ
Q36460480Vesicular release of ATP at central synapses

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