Lesions in DNA: hurdles for polymerases

scientific article

Lesions in DNA: hurdles for polymerases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0968-0004(99)01524-8
P698PubMed publication ID10664587

P2093author name stringFuchs RP
Baynton K
P2860cites workhRAD30 mutations in the variant form of xeroderma pigmentosumQ22010237
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zetaQ24323043
Deoxycytidyl transferase activity of yeast REV1 proteinQ27931173
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, PoletaQ27935465
Thymine-thymine dimer bypass by yeast DNA polymerase zetaQ27938043
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase etaQ28115711
Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading functionQ33594697
Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesisQ33771455
The T-T pyrimidine (6–4) pyrimidinone UV photoproduct is much less mutagenic in yeast than inEscherichia coliQ34753798
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.Q35588920
A model for a umuDC-dependent prokaryotic DNA damage checkpointQ35600001
Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelityQ36038818
The frequency and accuracy of replication past a thymine-thymine cyclobutane dimer are very different in Saccharomyces cerevisiae and Escherichia coliQ36099447
Inactivation of DNA proofreading obviates the need for SOS induction in frameshift mutagenesisQ36638036
Cellular strategies for accommodating replication-hindering adducts in DNA: control by the SOS response in Escherichia coliQ37441805
Impaired translesion synthesis in xeroderma pigmentosum variant extractsQ39444921
Mutagenesis induced by single UV photoproducts in E. coli and yeastQ40486483
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.Q41728302
Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricusQ42641653
A RecA protein mutant deficient in its interaction with the UmuDC complexQ43462173
DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions.Q43518631
Use of single-turnover kinetics to study bulky adduct bypass by T7 DNA polymeraseQ44408924
DNA repair: getting past a lesion - at a cost.Q53941431
Novel Mutagenic Properties of Abasic Sites inSaccharomyces cerevisiaeQ54606410
A umuDC-independent SOS pathway for frameshift mutagenesisQ67965605
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesisQ72994394
Mechanisms of frameshift mutations: insight from aromatic aminesQ73257198
The mutagenesis proteins UmuD' and UmuC prevent lethal frameshifts while increasing base substitution mutationsQ77231587
P433issue2
P1104number of pages6
P304page(s)74-79
P577publication date2000-02-01
P1433published inTrends in Biochemical SciencesQ1565711
P1476titleLesions in DNA: hurdles for polymerases
P478volume25

Reverse relations

cites work (P2860)
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Q42024376Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae
Q38324744DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.
Q34367279DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes.
Q40437426DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint
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Q36457110Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya
Q35013038poliota-dependent lesion bypass in vitro

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