review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | William C Copeland | |
Rachel Krasich | |||
P2860 | cites work | Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase | Q22010228 |
hRAD30 mutations in the variant form of xeroderma pigmentosum | Q22010237 | ||
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of Rous Sarcoma Virus | Q22122431 | ||
Premature ageing in mice expressing defective mitochondrial DNA polymerase | Q24294365 | ||
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells | Q24298399 | ||
Evidence for a direct role of the DNA polymerase gamma in the replication of the human mitochondrial DNA in vitro | Q24299498 | ||
PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication | Q24308876 | ||
Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates | Q24312975 | ||
Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma | Q24315156 | ||
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair | Q24317107 | ||
hPrimpol1/CCDC111 is a human DNA primase-polymerase required for the maintenance of genome integrity | Q24338411 | ||
PrimPol, an archaic primase/polymerase operating in human cells | Q24339480 | ||
Repriming of DNA synthesis at stalled replication forks by human PrimPol | Q24339613 | ||
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct | Q42934957 | ||
Genetic variation in genes encoding for polymerase ζ subunits associates with breast cancer risk, tumour characteristics and survival | Q43573965 | ||
DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate | Q46248276 | ||
Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea | Q46406774 | ||
Mitochondrial DNA polymerase POLIB is essential for minicircle DNA replication in African trypanosomes. | Q46499579 | ||
Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity | Q46705791 | ||
Structural insight into the DNA polymerase beta deoxyribose phosphate lyase mechanism. | Q46711159 | ||
Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity | Q47813121 | ||
Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes | Q48219294 | ||
Nomenclature of Eukaryotic DNA Polymerases | Q50724290 | ||
Disruption of the developmentally regulated Rev3l gene causes embryonic lethality. | Q52163744 | ||
Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. | Q52541352 | ||
Identification of a beta-like DNA polymerase activity in bovine heart mitochondria. | Q54063268 | ||
The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. Quantitative isolation of mitochondrial deoxyribonucleic acid. | Q54369042 | ||
Mitochondrial point mutations do not limit the natural lifespan of mice. | Q55043447 | ||
Multiple mitochondrial DNA polymerases in Trypanosoma brucei | Q56900777 | ||
PDIP38 Associates with Proteins Constituting the Mitochondrial DNA Nucleoid | Q57649553 | ||
A nuclear mutant of Saccharomyces cerevisiae deficient in mitochondrial DNA replication and polymerase activity | Q68884334 | ||
A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata | Q72302941 | ||
A DNA polymerase beta in the mitochondrion of the trypanosomatid Crithidia fasciculata | Q72591602 | ||
Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression | Q73039820 | ||
Construction of transgenic mice with tissue-specific acceleration of mitochondrial DNA mutagenesis | Q73076403 | ||
DNA polymerase gamma in mitochondrial DNA replication and repair | Q73523164 | ||
Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism | Q74615796 | ||
Identification and characterization of two DNA polymerase activities present in Trypanosoma brucei mitochondria | Q77089092 | ||
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes | Q80194521 | ||
Identification and functional analysis of human Tom22 for protein import into mitochondria | Q24551299 | ||
High-efficiency bypass of DNA damage by human DNA polymerase Q | Q24561381 | ||
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases | Q24630867 | ||
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance | Q24645172 | ||
A mitochondrial protein compendium elucidates complex I disease biology | Q24655079 | ||
Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members | Q24812840 | ||
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta | Q27648988 | ||
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP | Q27729369 | ||
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism | Q27729370 | ||
Sequence and organization of the human mitochondrial genome | Q27860659 | ||
Saccharomyces cerevisiae polymerase zeta functions in mitochondria | Q27929832 | ||
Replication past O(6)-methylguanine by yeast and human DNA polymerase eta. | Q27930712 | ||
Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. | Q27933302 | ||
Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase eta. | Q27934276 | ||
Role of polymerase η in mitochondrial mutagenesis of Saccharomyces cerevisiae | Q27935312 | ||
Role of DNA polymerase eta in the bypass of a (6-4) TT photoproduct | Q27939380 | ||
The structure and replication of kinetoplast DNA | Q28273252 | ||
Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage | Q28507940 | ||
Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance | Q28510356 | ||
Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis | Q28511104 | ||
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ | Q28543483 | ||
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination | Q28593605 | ||
Mitochondrial diseases in man and mouse | Q29614555 | ||
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging | Q29616056 | ||
Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities | Q30430241 | ||
Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro | Q30431649 | ||
The RAD30 cancer susceptibility gene | Q30883353 | ||
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals | Q33400985 | ||
REV3L confers chemoresistance to cisplatin in human gliomas: the potential of its RNAi for synergistic therapy | Q33574535 | ||
Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells | Q33594119 | ||
A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells | Q33676609 | ||
Mitochondrial genome maintenance in health and disease. | Q33821051 | ||
In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells | Q33903179 | ||
Molecular and clinical genetics of mitochondrial diseases due to POLG mutations | Q33936754 | ||
DNA repair in mammalian mitochondria: Much more than we thought? | Q37764794 | ||
Polymerase gamma disease through the ages | Q37785515 | ||
Minimizing the damage: repair pathways keep mitochondrial DNA intact | Q38044810 | ||
Inherited peripheral neuropathies due to mitochondrial disorders. | Q38207342 | ||
Kinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7,8-dihydro-8-oxo-2'-deoxyguanosine | Q38303938 | ||
Inhibition of REV3 expression induces persistent DNA damage and growth arrest in cancer cells | Q38826337 | ||
PrimPol-A new polymerase on the block | Q38866687 | ||
A role for DNA polymerase θ in the timing of DNA replication. | Q38978675 | ||
In situ hybridization to the Crithidia fasciculata kinetoplast reveals two antipodal sites involved in kinetoplast DNA replication | Q39227548 | ||
Crosstalk between replicative and translesional DNA polymerases: PDIP38 interacts directly with Poleta. | Q39692109 | ||
Animal mitochondrial DNA: an extreme example of genetic economy | Q39822739 | ||
PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities. | Q40404211 | ||
Yeast mitochondrial DNA polymerase is related to the family A DNA polymerases | Q40526382 | ||
Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes | Q40635878 | ||
Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation | Q40679872 | ||
Asymmetry of DNA replication and translesion synthesis of UV-induced thymine dimers | Q40686398 | ||
Yeast mitochondrial DNA mutators with deficient proofreading exonucleolytic activity | Q33938120 | ||
DNA polymerase of mitochondria is a gamma-polymerase | Q33998369 | ||
Eukaryotic DNA polymerases: proposal for a revised nomenclature. | Q34093113 | ||
RNA-dependent DNA polymerase in virions of RNA tumour viruses | Q34206460 | ||
Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast | Q34217894 | ||
Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases | Q34228142 | ||
Defects in mitochondrial DNA replication and human disease | Q34241192 | ||
Further characterization of human DNA polymerase delta interacting protein 38. | Q34409092 | ||
Molecular dissection of the domain architecture and catalytic activities of human PrimPol | Q34412816 | ||
Human PrimPol mutation associated with high myopia has a DNA replication defect | Q34440697 | ||
Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication | Q34604294 | ||
A new synthetic RNA-dependent DNA polymerase from human tissue culture cells (HeLa-fibroblast-synthetic oligonucleotides-template-purified enzymes). | Q34689792 | ||
Inherited mitochondrial diseases of DNA replication | Q34692482 | ||
Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins. | Q35097955 | ||
p53, aerobic metabolism, and cancer | Q35151326 | ||
Compilation and alignment of DNA polymerase sequences | Q35774285 | ||
Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome | Q35804949 | ||
POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity. | Q35999327 | ||
Analysis of Rev1p and Pol zeta in mitochondrial mutagenesis suggests an alternative pathway of damage tolerance. | Q36249278 | ||
Structure and mechanism of DNA polymerase Beta. | Q36389634 | ||
MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins | Q36434534 | ||
Insights into the Molecular Mechanism of Polymerization and Nucleoside Reverse Transcriptase Inhibitor Incorporation by Human PrimPol | Q36439125 | ||
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses | Q36637565 | ||
Multiple functions of DNA polymerases | Q36667353 | ||
Low-fidelity DNA synthesis by human DNA polymerase theta. | Q36740110 | ||
Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria | Q36845992 | ||
PrimPol prevents APOBEC/AID family mediated DNA mutagenesis | Q36959012 | ||
Oxidative DNA damage stalls the human mitochondrial replisome | Q37057236 | ||
TP53 mutation, mitochondria and cancer | Q37266021 | ||
Human mitochondrial DNA replication machinery and disease | Q37322422 | ||
Functional roles of DNA polymerases beta and gamma | Q37330636 | ||
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass | Q37340847 | ||
The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria | Q37452565 | ||
DNA2 resolves expanding flap in mitochondrial base excision repair | Q37668905 | ||
P304 | page(s) | 692-709 | |
P577 | publication date | 2017-01-01 | |
P1433 | published in | Frontiers in Bioscience | Q5506062 |
P1476 | title | DNA polymerases in the mitochondria: A critical review of the evidence | |
P478 | volume | 22 |
Q95841103 | "Mitochondrial Toolbox" - A Review of Online Resources to Explore Mitochondrial Genomics |
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Q47444998 | DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria |
Q53688741 | Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease. |
Q100316332 | Extreme heterogeneity of human mitochondrial DNA from organelles to populations |
Q47209159 | Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions |
Q49918141 | G4-Interacting DNA Helicases and Polymerases: Potential Therapeutic Targets. |
Q96229745 | Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patient |
Q57753617 | Mitochondrial DNA replication in mammalian cells: overview of the pathway |
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Q92155153 | Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology |
Q91715716 | Mitochondrial Homeostasis and Cellular Senescence |
Q50281263 | Mitochondrial genome variability: the effect on cellular functional activity. |
Q47125109 | Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance |
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Q55174541 | The presence of rNTPs decreases the speed of mitochondrial DNA replication. |
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