Mitochondrial diseases in man and mouse

scientific article (publication date: 5 March 1999)

Mitochondrial diseases in man and mouse is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.283.5407.1482
P3181OpenCitations bibliographic resource ID531448
P698PubMed publication ID10066162
P5875ResearchGate publication ID13224893

P2093author name stringWallace DC
P2860cites workThe genome sequence of Rickettsia prowazekii and the origin of mitochondriaQ22122428
Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementationQ29614475
P433issue5407
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)1482-8
P577publication date1999-03-05
P1433published inScienceQ192864
P1476titleMitochondrial diseases in man and mouse
P478volume283

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cites work (P2860)
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Q33773866Degree of glutathione deficiency and redox imbalance depend on subtype of mitochondrial disease and clinical status
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Q83292765Detection of mitochondrial fission with orientation-dependent optical Fourier filters
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Q39304113Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held
Q51892557Developmental regulation of mitochondrial biogenesis and function in the mouse mammary gland during a prolonged lactation cycle.
Q40273572Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function.
Q30956250Diagnosis and management of MELAS.
Q44768021Diagnostic criteria for pediatric multiple sclerosis
Q47804981Diagnostic value of mitochondrial DNA mutation analysis in juvenile unilateral ptosis
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Q44838381Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.
Q36494335Differential mitochondrial protein expression profiling in neurodegenerative diseases
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Q38884808Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux
Q60636832Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart
Q43099702Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.
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Q35002406Effect of structural modulation of polyphenolic compounds on the inhibition of Escherichia coli ATP synthase
Q45138789Effect of treating induced mitochondrial damage on embryonic development and epigenesis
Q73455558Effects of aerobic training on lactate and catecholaminergic exercise responses in mitochondrial myopathies
Q39086053Effects of airborne toxicants on pulmonary function and mitochondrial DNA damage in rodent lungs
Q37418521Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site
Q40068903Effects of imaging conditions on mitochondrial transport and length in larval motor axons of Drosophila
Q39733739Efficient cloning and engineering of entire mitochondrial genomes in Escherichia coli and transfer into transcriptionally active mitochondria
Q46856395Efficient execution of cell death in non-glycolytic cells requires the generation of ROS controlled by the activity of mitochondrial H+-ATP synthase
Q34623673Electron transport chain defects in heart failure
Q37488246Emerging roles of mitochondrial membrane dynamics in health and disease.
Q36967723Emerging therapies for mitochondrial disorders
Q42143277Endogenous mitochondrial oxidative stress in MnSOD-deficient mouse embryonic fibroblasts promotes mitochondrial DNA glycation
Q35131161Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress
Q38112040Endothelial cell energy metabolism, proliferation, and apoptosis in pulmonary hypertension.
Q77648336Enhanced apoptosis in prolonged cultures of senescent porcine pulmonary artery endothelial cells
Q44024800Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death
Q40407402Enhancement of cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line.
Q46325293Environmental Tobacco Smoke Alters Metabolic Systems in Adult Rats.
Q92357155Environmental factors modulated ancient mitochondrial DNA variability and the prevalence of rheumatic diseases in the Basque Country
Q41439002Enzymatic activities linked to cardiac energy metabolism of Trypanosoma evansi-infected rats and their possible functional correlations to disease pathogenesis
Q34367235Enzymology of mitochondrial base excision repair
Q34386766Epidemiology and treatment of mitochondrial disorders
Q90221699Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy
Q37734460Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects.
Q92093237Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy
Q35069310Eukaryotic genome evolution: rearrangement and coevolution of compartmentalized genetic information
Q63977301Evaluation and treatment of the human immunodeficiency virus-1-exposed infant
Q44329063Evaluation of (4-[18F]Fluorophenyl)triphenylphosphonium ion. A potential myocardial blood flow agent for PET.
Q35672377Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles
Q46414184Evaluation of the ROS Inhibiting Activity and Mitochondrial Targeting of Phenolic Compounds in Fibroblast Cells Model System and Enhancement of Efficiency by Natural Deep Eutectic Solvent (NADES) Formulation.
Q43963313Events upstream of mitochondrial protein import limit the oxidative capacity of fibroblasts in multiple mitochondrial disease
Q27939094Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity
Q22241227Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
Q46908915Evidence of adaptive evolution of alpine pheasants to high-altitude environment from mitogenomic perspective
Q38263989Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury
Q35064205Evolution of the mitochondrial fusion-fission cycle and its role in aging
Q54706275Evolutionary diversification of mitochondrial proteomes: implications for human disease.
Q51963096Evolvability suppression to stabilize far-sighted adaptations.
Q43869563Exogenous phospholipids specifically affect transmembrane potential of brain mitochondria and cytochrome C release.
Q44547134Experimental evidence against the mitochondrial theory of aging. A study of isolated human skeletal muscle mitochondria
Q34429365Exploring the catalytic core of complex I by Yarrowia lipolytica yeast genetics
Q40866706Expression of Rattus norvegicus mtDNA in Mus musculus cells results in multiple respiratory chain defects
Q46424917Expression of VDAC Regulated by Extracts of Limonium sinense Ktze root Against CCl4-induced Liver Damage
Q34601641Expression of a mitochondrial peroxiredoxin prevents programmed cell death in Leishmania donovani
Q30839671Extraction and annotation of human mitochondrial genomes from 1000 Genomes Whole Exome Sequencing data
Q35999424FABP4 reversed the regulation of leptin on mitochondrial fatty acid oxidation in mice adipocytes
Q40990028Faster and stronger manifestation of mitochondrial diseases in skeletal muscle than in heart related to cytosolic inorganic phosphate (Pi) accumulation
Q35459603Females with a mutation in a nuclear-encoded mitochondrial protein pay a higher cost of survival than do males in Drosophila.
Q64926601Fishing in the Cell Powerhouse: Zebrafish as A Tool for Exploration of Mitochondrial Defects Affecting the Nervous System.
Q46667460Flow cytometry in the study of mitochondrial respiratory chain disorders.
Q34500668Flow cytometry of isolated mitochondria during development and under some pathological conditions
Q43744100Fluorometric detection of ADP/ATP carrier deficiency in human muscle.
Q31920157Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints
Q37715192Foxo1 integrates insulin signaling with mitochondrial function in the liver
Q24674610Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck
Q35212591From genotype to phenotype: genetics and medical practice in the new millennium
Q36929305From mitochondria to disease: role of the renin-angiotensin system
Q33827866From sideroblastic anemia to the role of mitochondrial DNA mutations in myelodysplastic syndromes
Q37446931From structure to function: mitochondrial morphology, motion and shaping in vascular smooth muscle
Q36137537Function of GRIM-19, a mitochondrial respiratory chain complex I protein, in innate immunity
Q28552632Functional Characterization of Three Concomitant MtDNA LHON Mutations Shows No Synergistic Effect on Mitochondrial Activity
Q52867091Functional Mitochondria Are Important for the Effect of Resveratrol.
Q38213198Functional annotation of introns in mitochondrial genome--a brief review
Q33836224Functional brain imaging in the resting state and during activation in Alzheimer's disease. Implications for disease mechanisms involving oxidative phosphorylation
Q34540620Functional differences between mitochondrial haplogroup T and haplogroup H in HEK293 cybrid cells
Q46212405Functional expression of plant alternative oxidase decreases antimycin A-induced reactive oxygen species production in human cells
Q34142478Functional, structural, and genetic mitochondrial abnormalities in myocardial diseases
Q51598419Functionalized self-assembled monolayer on gold for detection of human mitochondrial tRNA gene mutations.
Q28273169Further evidence for paternal inheritance of mitochondrial DNA in the sheep (Ovis aries)
Q24561759GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I
Q44306254Ganglioside GT1B and melatonin inhibit brain mitochondrial DNA damage and seizures induced by kainic acid in mice
Q30514129Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model.
Q34623700Gene regulatory mechanisms governing energy metabolism during cardiac hypertrophic growth
Q34264448Gene therapy by mitochondrial transfer
Q34133279Gene therapy for progeny of mito-mice carrying pathogenic mtDNA by nuclear transplantation
Q36688667Gene therapy of the other genome: the challenges of treating mitochondrial DNA defects
Q34435173GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases.
Q73035349Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes
Q42950686Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.
Q37764795Generation, function, and prognostic utility of somatic mitochondrial DNA mutations in cancer
Q34688103Genes, mitochondria and aging in filamentous fungi
Q50203938Genetic Variants in the Manganese Superoxide Dismutase 2 Gene and in the Catalase Gene are not Associated With Alcoholic Chronic Pancreatitis.
Q93012161Genetic and morphometric categorization of Taenia ovis from Sheep in Iran
Q58490420Genetic characterization of Egyptian and Italian sheep breeds using mitochondrial DNA.
Q35112849Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy
Q61764128Genetic risk markers for hepatocellular carcinoma in patients with alcoholic liver disease
Q28397261Genetic variability of respiratory complex abundance, organization and activity in mouse brain
Q54349886Genetic variants of MnSOD and GPX1 and susceptibility to bladder cancer in a Turkish population.
Q33691714Genetic variation in PARL influences mitochondrial content
Q35132741Genetics and mitochondrial abnormalities in autism spectrum disorders: a review
Q34369881Genetics of familial paragangliomas: past, present, and future
Q27935978Genome-wide responses to mitochondrial dysfunction
Q35111415Geriatric oncology: a clinical approach to the older patient with cancer.
Q34576588Germline bottlenecks, biparental inheritance and selection on mitochondrial variants: a two-level selection model
Q94464138Gerontoxanthone I and Macluraxanthone Induce Mitophagy and Attenuate Ischemia/Reperfusion Injury
Q33991794Glia are critical for the neuropathology of complex I deficiency in Drosophila
Q34615869Glucose metabolism derangements in adults with the MELAS m.3243A>G mutation
Q51377105Glucose transporter type I deficiency causing mitochondrial dysfunction.
Q28505776Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo
Q46425686Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation
Q43998719Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide
Q30152650Granzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.
Q41918189Guidelines for the use of flow cytometry and cell sorting in immunological studies
Q37715573HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle
Q37424675Hallmarks of a new era in mitochondrial biochemistry
Q80611167Handling mammalian mitochondrial tRNAs and aminoacyl-tRNA synthetases for functional and structural characterization
Q35165702Have environmental mutagens caused oncomutations in people?
Q57458095Hepatocyte miR-33a mediates mitochondrial dysfunction and hepatosteatosis by suppressing NDUFA5
Q46712412Hepatoprotection of oleanolic acid is related to its inhibition on mitochondrial permeability transition
Q45138383Hepatoprotective activity of Terminalia catappa L. leaves and its two triterpenoids
Q37713095Heterogeneity in Cancer Metabolism: New Concepts in an Old Field
Q36501296Heteroplasmy as a common state of mitochondrial genetic information in plants and animals
Q34020757Heteroplasmy of the human mtDNA control region remains constant during life
Q34692062Heterozygous Polg mutation causes motor dysfunction due to mtDNA deletions
Q40479130High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines.
Q38494582High levels of gene expression explain the strong evolutionary constraint of mitochondrial protein-coding genes
Q55981909High-Resolution Genomic Analysis of Human Mitochondrial RNA Sequence Variation
Q46667465High-throughput assessment of mitochondrial membrane potential in situ using fluorescence resonance energy transfer
Q35208534High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects
Q36129409Hitting the brakes: termination of mitochondrial transcription
Q32138928How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology
Q38968532HtrA2/Omi influences the stability of LON protease 1 and prohibitin, proteins involved in mitochondrial homeostasis
Q28115572Human Myo19 is a novel myosin that associates with mitochondria
Q37322422Human mitochondrial DNA replication machinery and disease
Q38247491Human mitochondrial genome flaws and risk of cancer
Q42537947Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein
Q33943662Human mitochondrial topoisomerase I
Q28215338Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA
Q24313359Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity
Q74159658Human quadriceps muscle mitochondria: a functional characterization
Q44435551Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity.
Q48784381Human-animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate.
Q90598570HyPer2 imaging reveals temporal and heterogeneous hydrogen peroxide changes in denervated and aged skeletal muscle fibers in vivo
Q38894828Hydrophobized triphenyl phosphonium derivatives for the preparation of mitochondriotropic liposomes: choice of hydrophobic anchor influences cytotoxicity but not mitochondriotropic effect.
Q37034432Hyperglycemic Conditions Prime Cells for RIP1-dependent Necroptosis.
Q35113389Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion
Q93105365Hypoxia induces rapid, STAT3 and ROS dependent, mitochondrial translocation of RelA(p65) and IκBα
Q37036607IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis
Q37855570IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging
Q35370058IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease
Q64963573Identification and Characterization of New RNASEH1 Mutations Associated With PEO Syndrome and Multiple Mitochondrial DNA Deletions.
Q34547595Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells
Q35908442Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control
Q33231204Identification of a putative mitochondrial RNA polymerase from Physarum polycephalum: characterization, expression, purification, and transcription in vitro
Q33942032Identification of a ryanodine receptor in rat heart mitochondria
Q37413833Identification of mitochondrial disease genes through integrative analysis of multiple datasets
Q33325706Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol
Q92924523Imaging Mitochondrial Functions: from Fluorescent Dyes to Genetically-Encoded Sensors
Q90332429Iminosugars Spiro-Linked with Morpholine-Fused 1,2,3-Triazole: Synthesis, Conformational Analysis, Glycosidase Inhibitory Activity, Antifungal Assay, and Docking Studies
Q36615718Immature Rubus coreanus Shows a Free Radical-Scavenging Effect and Inhibits Cholesterol Synthesis and Secretion in Liver Cells
Q90016261Immunosuppressant drug tacrolimus induced mitochondrial nephrotoxicity, modified PCNA and Bcl-2 expression attenuated by Ocimum basilicum L. in CD1 mice
Q28578564Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone
Q52541455Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.
Q84987787Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice
Q35252601Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels.
Q34793219Import and assembly of proteins into mitochondria of mammalian cells
Q39693264In Saccharomyces cerevisiae, ATP2 mRNA sorting to the vicinity of mitochondria is essential for respiratory function
Q81554465In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes
Q39227742In vitro 3'-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness
Q44298045In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.
Q41807410In vivo and in vitro assessment of brain bioenergetics in aging rats
Q34777508In vivo effects of dietary quercetin and quercetin-rich red onion extract on skeletal muscle mitochondria, metabolism, and insulin sensitivity
Q34057751In vivo oxygen-17 NMR for imaging brain oxygen metabolism at high field
Q34405677In vivo quantification reveals extensive natural variation in mitochondrial form and function in Caenorhabditis briggsae
Q27931938Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.
Q57537758Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury
Q43628476Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener
Q34381144Increased mitochondrial mass in mitochondrial myopathy mice
Q48910103Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease.
Q46888735Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment
Q46555080Increased oxidative damage with altered antioxidative status in type 2 diabetic patients harboring the 16189 T to C variant of mitochondrial DNA.
Q24542578Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster
Q34184643Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype.
Q40482450Influence of a mitochondrial genetic defect on capacitative calcium entry and mitochondrial organization in the osteosarcoma cells.
Q39991458Influence of mitochondrial DNA level on cellular energy metabolism: implications for mitochondrial diseases
Q40394628Inheritance of mitochondrial disorders
Q37129457Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia
Q34692482Inherited mitochondrial diseases of DNA replication
Q38649815Inherited mitochondrial genomic instability and chemical exposures
Q39704890Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.
Q51642781Inhibition of mitochondrial complex-1 restores the downregulation of aquaporins in obstructive nephropathy.
Q35042398Inhibition of mitochondrial proton F0F1-ATPase/ATP synthase by polyphenolic phytochemicals
Q21296696Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms
Q44152179Inhibition of the mitochondrial respiratory chain by alanine in rat cerebral cortex
Q44027584Inhibition of the mitochondrial respiratory chain by phenylalanine in rat cerebral cortex
Q43921784Inhibition of the mitochondrial respiratory chain complex activities in rat cerebral cortex by methylmalonic acid.
Q42134189Inhibition sites in F1-ATPase from bovine heart mitochondria.
Q34633928Initial experience in the treatment of inherited mitochondrial disease with EPI-743.
Q38802167Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.
Q34127625Insight into nanoparticle cellular uptake and intracellular targeting
Q35776712Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans
Q37715179Insulin signaling meets mitochondria in metabolism
Q44532294Insulin-like growth factor-1 prevents loss of electrochemical gradient in cardiac muscle mitochondria via activation of PI 3 kinase/Akt pathway.
Q28593536Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
Q98177448Integrating Ultra-Weak Photon Emission Analysis in Mitochondrial Research
Q24793149Integrative analysis of the mitochondrial proteome in yeast
Q27629213Integrity ofthermus thermophiluscytochrome c552Synthesized byescherichia colicells expressing the host-specific cytochromecmaturation genes,ccmABCDEFGH: Biochemical, spectral, and structural characterization of the recombinant protein
Q45878904Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA.
Q24314111Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury
Q88442582Intraspecific mitochondrial genome comparison identified CYTB as a high-resolution population marker in a new pest Athetis lepigone
Q46457362Introgression of mtDNA in Urosaurus lizards: historical and ecological processes
Q41549302Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis
Q34013010Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.
Q36031463Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
Q43886867Ischemic preconditioning and Na+/H+ exchange inhibition improve reperfusion ion homeostasis
Q28217558Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation
Q73944610Isolation and subfractionation of mitochondria from the yeast Saccharomyces cerevisiae
Q40828951Isolation of a bi-directional promoter directing expression of the mouse GABPalpha and ATP synthase coupling factor 6 genes.
Q42160127Japanese Alzheimer's disease and other complex disorders diagnosis based on mitochondrial SNP haplogroups
Q39363091Junctophilin 2 knockdown interfere with mitochondrium status in ESC-CMs and cardiogenesis of ES cells
Q35109723KIOM-4 Protects against Oxidative Stress-Induced Mitochondrial Damage in Pancreatic β-cells via Its Antioxidant Effects
Q35755707Kidney-Specific Reduction of Oxidative Phosphorylation Genes Derived from Spontaneously Hypertensive Rat.
Q28283648L-2-Hydroxyglutaric aciduria: identification of a mutant gene C14orf160, localized on chromosome 14q22.1
Q36826689LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism
Q33974957LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein
Q34627398Laboratory diagnosis of metabolic myopathies
Q43757469Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice.
Q26863599Leber hereditary optic neuropathy: current perspectives
Q28768948Likelihood Analysis of Asymmetrical Mutation Bias Gradients in Vertebrate Mitochondrial Genomes
Q33893542Linking chemical electron-proton transfer to proton pumping in cytochrome c oxidase: broken-symmetry DFT exploration of intermediates along the catalytic reaction pathway of the iron-copper dinuclear complex
Q51660260Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1.
Q35947255Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo
Q34447070Localization of mitochondrial DNA encoded cytochrome c oxidase subunits I and II in rat pancreatic zymogen granules and pituitary growth hormone granules
Q37634512Long term adverse effects related to nucleoside reverse transcriptase inhibitors: clinical impact of mitochondrial toxicity
Q54467516Loss of a primordial identity element for a mammalian mitochondrial aminoacylation system.
Q36382575Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy.
Q33679205Low penetrance of Leber's hereditary optic neuropathy in ten Han Chinese families carrying the ND6 T11484C mutation
Q94352872L’évaluation et le traitement du nourrisson exposé au virus d’immunodéficience humaine de type 1
Q45861723MITO-Porter for Mitochondrial Delivery and Mitochondrial Functional Analysis
Q38504142MITOCHONDRIAL REDOX IMAGING FOR CANCER DIAGNOSTIC AND THERAPEUTIC STUDIES
Q39541857MITOP, the mitochondrial proteome database: 2000 update
Q30384428MPV17-associated hepatocerebral mitochondrial DNA depletion syndrome: new patients and novel mutations.
Q36129109MaGelLAn 1.0: a software to facilitate quantitative and population genetic analysis of maternal inheritance by combination of molecular and pedigree information.
Q42374188Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells
Q33334641Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast
Q37763932Mammalian mitochondrial proteomics: insights into mitochondrial functions and mitochondria-related diseases
Q28140976Mammalian mitochondrial ribosomal proteins (4). Amino acid sequencing, characterization, and identification of corresponding gene sequences
Q33778100Manganese superoxide dismutase V16A single-nucleotide polymorphism in the mitochondrial targeting sequence is associated with reduced enzymatic activity in cryopreserved human hepatocytes
Q44122031Manipulation of mitochondrial DNA gene expression in the mouse
Q47612283Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrow
Q57282162Maternal component in the familial aggregation of hypertension
Q35845825Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.
Q26849450Maternal inheritance of mitochondrial DNA by diverse mechanisms to eliminate paternal mitochondrial DNA
Q43664500Measurements of protein carbonyls, ortho- and meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats
Q43001982Mechanism in the reaction of cytochrome c oxidase with organic hydroperoxides: an ESR spin-trapping investigation
Q27647277Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols
Q28131760Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
Q37468328Mechanisms underlying metabolic and neural defects in zebrafish and human multiple acyl-CoA dehydrogenase deficiency (MADD).
Q37511851Mechanotransduction and Metabolism in Cardiomyocyte Microdomains.
Q36525492Medicinal chemistry of ATP synthase: a potential drug target of dietary polyphenols and amphibian antimicrobial peptides
Q48223108Melas with point mutations involving tRNALeu (A3243G) and tRNAGlu(A14693g)
Q35001051Melatonin in mitochondrial dysfunction and related disorders
Q40121244Metabolic and antioxidant system alterations in an astrocytoma cell line challenged with mitochondrial DNA deletion
Q37217309Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.
Q37617074Metabolic imaging in multiple time scales
Q28384779Metabolic regulation of manganese superoxide dismutase expression via essential amino acid deprivation
Q92685482Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles
Q34132623Metabolism and lifespan
Q36693111Metabolism pathways in chronic lymphocytic leukemia
Q37701655Metabolite measurements in the caudate nucleus, anterior cingulate cortex and hippocampus among patients with mitochondrial disorders: a case-control study using proton magnetic resonance spectroscopy
Q36056367Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability
Q26863224Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury
Q46327960Methylene blue and its analogues as antidepressant compounds.
Q47660144Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal
Q30484862Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy
Q51553464MicroRNA array analysis of microRNAs related to systemic scleroderma.
Q30634345Microphotometric analysis of NADH-tetrazolium reductase deficiency in fibroblasts of patients with Leber hereditary optic neuropathy.
Q42799263Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction
Q89422097Mito-mice∆ and mitochondrial DNA mutator mice as models of human osteoporosis caused not by aging but by hyperparathyroidism
Q42175820MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria
Q34667750MitoLSDB: a comprehensive resource to study genotype to phenotype correlations in human mitochondrial DNA variations
Q41878294MitoLoc: A method for the simultaneous quantification of mitochondrial network morphology and membrane potential in single cells
Q34084587MitoMiner: a data warehouse for mitochondrial proteomics data
Q24671804Mitochondria
Q38741503Mitochondria and Mitochondrial ROS in Cancer: Novel Targets for Anticancer Therapy
Q37431693Mitochondria and cancer
Q35894464Mitochondria and mind
Q35540388Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice
Q36359505Mitochondria as a target for early detection and diagnosis of cancer
Q34264441Mitochondria as subcellular targets for clinically useful anthracyclines
Q42487268Mitochondria buffer non-toxic calcium loads and release calcium through the mitochondrial permeability transition pore and sodium/calcium exchanger in rat basal forebrain neurons
Q33737272Mitochondria harbouring mutant mtDNA--a cuckoo in the nest?
Q28394886Mitochondria in the pathogenesis of diabetes: a proteomic view
Q37990817Mitochondria in vascular disease
Q64245244Mitochondria-Responsive Drug Release along with Heat Shock Mediated by Multifunctional Glycolipid Micelles for Precise Cancer Chemo-Phototherapy
Q35164499Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae
Q35108107Mitochondria-related male infertility
Q36262408Mitochondria-related miR-141-3p contributes to mitochondrial dysfunction in HFD-induced obesity by inhibiting PTEN.
Q36846818Mitochondria: a hub of redox activities and cellular distress control
Q35071387Mitochondria: releasing power for life and unleashing the machineries of death
Q36671535Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl
Q37316455Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations
Q35577705Mitochondrial Bioenergetics, Aging, and Aging-Related Disease
Q45144296Mitochondrial DNA 3644T-->C mutation associated with bipolar disorder
Q64230639Mitochondrial DNA Fitness Depends on Nuclear Genetic Background in
Q37030177Mitochondrial DNA aberrations of bone marrow cells from patients with aplastic anemia
Q73721797Mitochondrial DNA alteration in esophageal cancer
Q28141431Mitochondrial DNA and disease
Q37621771Mitochondrial DNA and functional investigations into the radiosensitivity of four mouse strains.
Q35789945Mitochondrial DNA as a cancer biomarker
Q35418164Mitochondrial DNA content varies with pathological characteristics of breast cancer
Q30760899Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection
Q35645470Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: implications for aging
Q40877362Mitochondrial DNA depletion causes morphological changes in the mitochondrial reticulum of cultured human cells
Q28649392Mitochondrial DNA disease and developmental implications for reproductive strategies
Q58912088Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis
Q57174226Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning
Q49605186Mitochondrial DNA in Lung Cancer.
Q34106586Mitochondrial DNA inheritance in Saccharomyces cerevisiae
Q34264471Mitochondrial DNA metabolism targeting drugs
Q48224759Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice
Q37735748Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome
Q28304162Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer
Q28250500Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer
Q38889446Mitochondrial DNA mutations and polymorphisms in asthenospermic infertile men.
Q34589585Mitochondrial DNA mutations in mutator mice confer respiration defects and B-cell lymphoma development
Q51661489Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.
Q35582417Mitochondrial DNA mutations in the hematopoietic system
Q33997161Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.
Q74394247Mitochondrial DNA mutations, oxidative stress, and aging
Q53624950Mitochondrial DNA oxidative damage contributes to cardiomyocyte ischemia/reperfusion-injury in rats: cardioprotective role of lycopene.
Q21144317Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration
Q36960466Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis
Q34994585Mitochondrial DNA repair and aging
Q39140349Mitochondrial DNA sequence and phylogenetic evaluation of geographically disparate Sus scrofa breeds.
Q92586273Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection
Q35848412Mitochondrial DNA spectra of single human CD34+ cells, T cells, B cells, and granulocytes
Q54938047Mitochondrial DNA transmission and confounding mitochondrial influences in cloned cattle and pigs.
Q80923272Mitochondrial DNA turnover occurs during preimplantation development and can be modulated by environmental factors
Q73692274Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer
Q37128695Mitochondrial DNA with a large-scale deletion causes two distinct mitochondrial disease phenotypes in mice
Q47974460Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Rat Model: Protective Effect of Epigallocatechin Gallate
Q73701269Mitochondrial Disease
Q62397450Mitochondrial Disorders
Q42226725Mitochondrial Dynamics in Mitochondrial Diseases
Q73627919Mitochondrial Genetics...and a new way to rescue them
Q35969962Mitochondrial Haplotypes Influence Metabolic Traits in Porcine Transmitochondrial Cybrids.
Q40726482Mitochondrial K(ATP) channel openers activate the ERK kinase by an oxidant-dependent mechanism
Q57847919Mitochondrial Membrane Potential and ATP Production in Primary Disorders of ATP Synthase
Q38678063Mitochondrial Mutations in Cardiac Disorders
Q40067062Mitochondrial ND5 gene variation associated with encephalomyopathy and mitochondrial ATP consumption
Q36702313Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells
Q33820008Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome
Q41927221Mitochondrial Oxidative Phosphorylation System (OXPHOS) Deficits in Schizophrenia: Possible Interactions with Cellular Processes
Q91914273Mitochondrial Respiratory Disorders: A Perspective on their Metabolite Biomarkers and Implications for Clinical Diagnosis and Therapeutic Intervention
Q41786761Mitochondrial Sensorineural Hearing Loss: A Retrospective Study and a Description of Cochlear Implantation in a MELAS Patient
Q77291654Mitochondrial Toxicity Associated with Nucleoside Reverse Transcriptase Inhibitor Therapy
Q41617454Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration
Q37692490Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals
Q33876294Mitochondrial biogenesis defects and neuromuscular disorders
Q36499708Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis
Q42015474Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis
Q36771650Mitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseases
Q57287805Mitochondrial biology and prostate cancer ethnic disparity
Q55072954Mitochondrial biology in reproduction.
Q34264422Mitochondrial contributions to cancer cell physiology: potential for drug development
Q29617739Mitochondrial control of cell death
Q37534178Mitochondrial control region alterations and breast cancer risk: a study in South Indian population
Q50858174Mitochondrial cytochrome c oxidase subunit II variations predict adverse prognosis in cytogenetically normal acute myeloid leukaemia.
Q38180688Mitochondrial cytopathies and cardiovascular disease
Q24799964Mitochondrial defects in cancer
Q34366678Mitochondrial defects in neurodegenerative disease
Q28510070Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
Q34660403Mitochondrial diabetes mellitus
Q34737294Mitochondrial diabetes: pathophysiology, clinical presentation, and genetic analysis
Q79341034Mitochondrial disorders and ataxia
Q33793717Mitochondrial disorders. A diagnostic challenge in clinical chemistry
Q91618895Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity
Q34545756Mitochondrial dynamics in mammals
Q38625440Mitochondrial dynamics, mitophagy and cardiovascular disease.
Q34811509Mitochondrial dysfunction and Down's syndrome.
Q36239813Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence?
Q50432740Mitochondrial dysfunction and myoclonic epilepsy: cause or effect or both?
Q35136214Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: experimental clarifications and persistent clinical questions
Q34137363Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia
Q35232104Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disorders
Q34282032Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins
Q34990992Mitochondrial dysfunction during sepsis: still more questions than answers.
Q24630557Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis
Q35903564Mitochondrial dysfunction in cancer
Q37455446Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids
Q35557675Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease
Q34144271Mitochondrial encephalomyopathy and complex III deficiency associated with a stop-codon mutation in the cytochrome b gene
Q30890554Mitochondrial encephalopathy
Q46361960Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes syndrome with hypothyroidism and focal segmental glomerulosclerosis in a paediatric patient
Q36070074Mitochondrial energy metabolism in heart failure: a question of balance
Q26824822Mitochondrial function and dysfunction: an update
Q34462332Mitochondrial function in normal and diabetic beta-cells
Q34594198Mitochondrial functions and aging
Q51656021Mitochondrial fusion provides an 'initial metabolic complementation' controlled by mtDNA.
Q35120186Mitochondrial gene history and mRNA localization: is there a correlation?
Q36740555Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis.
Q33821051Mitochondrial genome maintenance in health and disease.
Q33873854Mitochondrial genotype segregation and effects during mammalian development: applications to biotechnology
Q34163287Mitochondrial haplogroups and control region polymorphisms in age-related macular degeneration: a case-control study
Q51788256Mitochondrial haplogroups associated with Japanese Alzheimer's patients.
Q53303487Mitochondrial haplogroups associated with Japanese centenarians, Alzheimer's patients, Parkinson's patients, type 2 diabetic patients and healthy non-obese young males.
Q35952222Mitochondrial haplogroups define two phenotypes of osteoarthritis.
Q24804344Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
Q34344644Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity
Q37362132Mitochondrial iron accumulation with age and functional consequences
Q35606693Mitochondrial medicine for aging and neurodegenerative diseases
Q33836633Mitochondrial membrane perturbations in cholestasis.
Q33609715Mitochondrial metabolism and diabetes
Q33214287Mitochondrial mutagenesis and oxidative stress in human prostate cancer
Q33732618Mitochondrial mutagenesis in human cells and tissues
Q37311021Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma
Q43628481Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans
Q34561515Mitochondrial mutations may drive Y chromosome evolution
Q53675259Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency.
Q37015652Mitochondrial nuclear receptors and transcription factors: who's minding the cell?
Q36270598Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice
Q36626374Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics
Q45001313Mitochondrial oxidative phosphorylation transcriptome alterations in human amyotrophic lateral sclerosis spinal cord and blood
Q28593572Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
Q34423769Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila
Q33943645Mitochondrial polymorphism A10398G and Haplogroup I are associated with Fuchs' endothelial corneal dystrophy
Q42748320Mitochondrial protection by the thioredoxin-2 and glutathione systems in an in vitro endothelial model of sepsis
Q36735868Mitochondrial protein import and human health and disease
Q36697530Mitochondrial rRNA and tRNA and hearing function
Q38821544Mitochondrial remodeling: Rearranging, recycling, and reprogramming
Q36119450Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism
Q38299817Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span
Q50584261Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming.
Q27348908Mitochondrial structure and function are disrupted by standard isolation methods
Q35914830Mitochondrial tRNA 3' end metabolism and human disease.
Q26828352Mitochondrial tRNA mutations and disease
Q36668719Mitochondrial targeting of recombinant RNAs modulates the level of a heteroplasmic mutation in human mitochondrial DNA associated with Kearns Sayre Syndrome
Q35017647Mitochondrial threshold effects.
Q46881541Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.
Q35550221Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective
Q24299860Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA
Q30476644Mitochondrial transfer between cells can rescue aerobic respiration
Q37347784Mitochondrial-Nuclear Interactions Mediate Sex-Specific Transcriptional Profiles in Drosophila.
Q33836653Mitochondrial-nuclear interactions and lifespan control in fungi
Q33991805Mitochondrially targeted antioxidants and thiol reagents
Q41108935Mitochondrially-imported RNA in drug discovery
Q36522646Mitoenergetic failure in Alzheimer disease
Q43478776Mitonuclear Interactions Mediate Transcriptional Responses to Hypoxia in Drosophila
Q39132336Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms.
Q92633565Mitophagy in Alzheimer's Disease and Other Age-Related Neurodegenerative Diseases
Q39149860Mitophagy in neurodegeneration and aging.
Q26776469Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy
Q44771659Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases
Q33796387Model systems for redox cofactor activity
Q45221017Modification of radiation damage to mitochondrial system in vivo by Podophyllum hexandrum: mechanistic aspects.
Q77876813Modulating heteroplasmy
Q44234584Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.
Q33833886Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells
Q38016561Modulation of telomere binding proteins: a future area of research for skin protection and anti-aging target
Q34615857Molecular bases of cellular iron toxicity
Q28508683Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains
Q37785514Molecular genetics of mitochondrial disorders
Q33841122Molecular interactions of cancer and age.
Q33875611Molecular oncology focus - is carcinogenesis a 'mitochondriopathy'?
Q34373141Morphological dynamics of mitochondria--a special emphasis on cardiac muscle cells
Q36479150Mother's curse: the effect of mtDNA on individual fitness and population viability
Q52021400Mother's mitochondria and optimal offspring sex ratio.
Q33503932MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease
Q35198793Multiphoton excited fluorescent materials for frequency upconversion emission and fluorescent probes.
Q28594703Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
Q49578903Multiple ways to prevent transmission of paternal mitochondrial DNA for maternal inheritance in animals.
Q37404541Multisystem manifestations of mitochondrial disorders
Q34150861Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy
Q43098981Musings about the effects of environment on photosynthesis
Q44957600Mutagenesis by transient misalignment in the human mitochondrial DNA control region
Q34478495Mutagenic analysis of the F0 stator subunits
Q40231756Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences
Q24794136Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells
Q38334427Mutations in the spacer region of Drosophila mitochondrial DNA polymerase affect DNA binding, processivity, and the balance between Pol and Exo function
Q33210189Mutations of mitochondrial 12S rRNA in gastric carcinoma and their significance
Q35587467My approach to oncocytic tumours of the thyroid
Q43280918Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis.
Q90371571NDUFV2 pseudogene (NDUFV2P1) contributes to mitochondrial complex I deficits in schizophrenia
Q34074236NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance.
Q37176104NOX enzymes as novel targets for drug development
Q35985407NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress
Q36703351Nanotechnology inspired tools for mitochondrial dysfunction related diseases
Q34162430Natural radioactivity and human mitochondrial DNA mutations
Q47112971Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration
Q36762857Neuroimaging in mitochondrial disorders
Q42908536Neuroinflammation, Oxidative Stress and the Pathogenesis of Parkinson's Disease
Q37408409Neurometabolic disorders and dysfunction in autism spectrum disorders
Q64079076Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O Consumption and ROS Release
Q35196229Neuronal ageing from an intraneuronal perspective: roles of endoplasmic reticulum and mitochondria
Q33881866Neurotoxicity associated with neuroleptic-induced oral dyskinesias in rats. Implications for tardive dyskinesia?
Q33892767New features of mitochondrial DNA replication system in yeast and man.
Q37291226New insights in the pathogenesis of multiple sclerosis--role of acrolein in neuronal and myelin damage
Q46990994New variants in the mitochondrial genomes of schizophrenic patients
Q28709961Next generation sequencing and comparative analyses of Xenopus mitogenomes
Q39499163Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin
Q31115741Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization
Q37121433Normal mitochondrial respiratory function is essential for spatial remote memory in mice
Q90661779Novel biallelic variants in MSTO1 associated with mitochondrial myopathy
Q46009324Novel human mitochondrial tRNA phe mutation in a patient with hearing impairment: a case study.
Q41813058Novel m.15434C>A (p.230L>I) Mitochondrial Cytb Gene Missense Mutation Associated with Dilated Cardiomyopathy
Q93352759Novel mutations in the mitochondrial complex I assembly gene NDUFAF5 reveal heterogeneous phenotypes
Q34116250Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
Q28396642Nuclear DNA damage signalling to mitochondria in ageing
Q45022855Nuclear DNA-encoded tRNAs targeted into mitochondria can rescue a mitochondrial DNA mutation associated with the MERRF syndrome in cultured human cells.
Q39236946Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease
Q37112850Nucleoid localization of Hsp40 Mdj1 is important for its function in maintenance of mitochondrial DNA
Q37068704Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.
Q89877024Nutritional geometry of mitochondrial genetic effects on male fertility
Q34805446Obesity and hepatosteatosis in mice with enhanced oxidative DNA damage processing in mitochondria
Q53341563Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
Q35663083Oocyte quality is decreased in women with minimal or mild endometriosis
Q27334237Opa1 is required for proper mitochondrial metabolism in early development
Q38212813Ophthalmic manifestations of inherited neurodegenerative disorders
Q42165515Oral administration of orthovanadate and Trigonella foenum graecum seed power restore the activities of mitochondrial enzymes in tissues of alloxan-induced diabetic rats
Q35690379Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
Q24298232Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells
Q34571312Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATP
Q51724662Overexpression of the alternative oxidase restores senescence and fertility in a long-lived respiration-deficient mutant of Podospora anserina.
Q58581080Overriding Phthalate Decomposition When Exploring Mycophenolic Acid Intermediates as Selenium-Based ROS Biological Probes
Q34114363Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism
Q42839708Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae
Q35023216Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences
Q38818702Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease.
Q35606429Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia
Q41141816Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications
Q41526360Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies
Q33774187Oxidative damage and age-related macular degeneration
Q58726639Oxidative status of cardinal ligament in pelvic organ prolapse
Q37566969Oxidative status predicts quality in human mesenchymal stem cells
Q74341665Oxidative stress and apoptosis
Q36019900Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes.
Q33921185Oxidative stress induced age dependent meibomian gland dysfunction in Cu, Zn-superoxide dismutase-1 (Sod1) knockout mice
Q53266394Oxidative stress level in circulating neutrophils is linked to neurodegenerative diseases.
Q37956881Oxidative stress, frailty and cognitive decline
Q38094613Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis
Q37355397Oxygen control of intracellular distribution of mitochondria in muscle fibers
Q43606174Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes
Q34000773PARP inhibition delays progression of mitochondrial encephalopathy in mice.
Q35691132PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
Q35705486PNPASE and RNA trafficking into mitochondria
Q35613347POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA.
Q28508508PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein
Q92901825PUMILIO1 Links Epilepsy to Spinocerebellar Ataxia
Q28506059Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival
Q74554779Paradoxes in longevity: sequence analysis of mtDNA haplogroup J in centenarians
Q44833660Paradoxical decrease of mitochondrial DNA deletions in epithelial cells of active ulcerative colitis patients
Q35113387Pathogenic expression of homoplasmic mtDNA mutations needs a complex nuclear-mitochondrial interaction
Q48202720Pathogenic mitochondrial DNA-induced respiration defects in hematopoietic cells result in anemia by suppressing erythroid differentiation
Q58040388Pathways related to mitochondrial dysfunction in cartilage of endemic osteoarthritis patients in China
Q35814781Patterns of natural selection acting on the mitochondrial genome of a locally adapted fish species
Q34884970Peptide-based carbon nanotubes for mitochondrial targeting
Q33373844Performance of mitochondrial DNA mutations detecting early stage cancer
Q37526796Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
Q37497833Pharmacological approaches to restore mitochondrial function
Q34807192Pharmacological control of cellular calcium handling in dystrophic skeletal muscle
Q33993644Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.
Q40643080Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia).
Q49887032Physiological Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand.
Q38587871Physiological roles of mitochondrial fission in cultured cells and mouse development
Q27935689Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability
Q92665725Polycystic ovary syndrome and mitochondrial dysfunction
Q33604703Polymorphisms in the mitochondrial DNA control region and frailty in older adults
Q44602602Possible antioxidant and neuroprotective mechanisms of FK506 in attenuating haloperidol-induced orofacial dyskinesia
Q24338278Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control
Q44248025Postlipopolysaccharide oxidative damage of mitochondrial DNA.
Q79154601Potential clinical applications using stem cells derived from human umbilical cord blood
Q36700182Power and SNP tagging in whole mitochondrial genome association studies
Q98291826Prediction of the Impact of Deleterious Nonsynonymous Single Nucleotide Polymorphisms on the Human RRM2B Gene: A Molecular Modeling Study
Q36103197Preimplantation death of xenomitochondrial mouse embryo harbouring bovine mitochondria
Q50761333Prevention of apoptosis by deferoxamine during 4 hours of cold cardioplegia and reperfusion: in vitro study of isolated working rat heart model.
Q40900379Prevention of neurodegeneration by a neuroprotective radical scavenger
Q26797996Primer removal during mammalian mitochondrial DNA replication
Q39753791Pro-oxidant properties of AZT and other thymidine analogues in macrophages: implication of the azido moiety in oxidative stress
Q80341733Proliferation of mitochondria in chronically stimulated rabbit skeletal muscle--transcription of mitochondrial genes and copy number of mitochondrial DNA
Q35117918Prooxidant properties of p66shc are mediated by mitochondria in human cells
Q43593930Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore.
Q90699227Protective effect of theaflavin on glycoprotein components and TCA cycle enzymes in high-fat diet and streptozotocin-induced diabetic rats
Q36387714Protective effects of sirtuins in cardiovascular diseases: from bench to bedside
Q38359199Protective role of melatonin in mitochondrial dysfunction and related disorders
Q33690022Proteogenomics Reveals Enriched Ribosome Assembly and Protein Translation in Pectoralis major of High Feed Efficiency Pedigree Broiler Males.
Q44280967Proteome analysis reveals phosphorylation of ATP synthase beta -subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes.
Q44417232Proteomic Consequences of a Human Mitochondrial tRNA Mutation beyond the Frame of Mitochondrial Translation
Q54687587Proteomic analysis of cancer-cell mitochondria
Q42065903Proteomic analysis of mitochondrial protein turnover: identification of novel substrate proteins of the matrix protease pim1.
Q53241728Proteomic approaches in understanding a detected relationship between chemotherapy-induced nephrotoxicity and cell respiration in HK-2 cells.
Q33947294Proteomic method identifies proteins nitrated in vivo during inflammatory challenge
Q33799381Proteomic survey towards the tissue-specific proteins of mouse mitochondria
Q35241298Proteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome
Q58857942Proteomics in the Systems-Level Study of the Metabolic Syndrome
Q36591226Psychiatric symptoms correlate with metabolic indices in the hippocampus and cingulate in patients with mitochondrial disorders.
Q36595558Purity matters: A workflow for the valid high-resolution lipid profiling of mitochondria from cell culture samples
Q42277191Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics?
Q26862395Quality matters: how does mitochondrial network dynamics and quality control impact on mtDNA integrity?
Q48445579Quantification of oxygen metabolic rates in Human brain with dynamic 17 O MRI: Profile likelihood analysis.
Q48324144Quantification of total mitochondrial DNA and mitochondrial common deletion in the frontal cortex of patients with schizophrenia and bipolar disorder
Q39016138Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells.
Q73606018Quantitative plasmid mixture analysis using the fluorogenic 5'-nuclease polymerase chain reaction assay
Q34264482RNA delivery into mitochondria
Q28586228RNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cells
Q40636632Radiation protection of HepG2 cells by Podophyllum hexandrum Royale
Q36955833Radical-free biology of oxidative stress
Q39413342Random intracellular drift explains the clonal expansion of mitochondrial DNA mutations with age.
Q36025504Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck
Q34156841Re-engineering the mitochondrial genomes in mammalian cells
Q26851203Reactive oxygen species in health and disease
Q36459995Reactive oxygen species-mediated mitochondria-to-nucleus signaling: a key to aging and radical-caused diseases
Q26821921Receptor-mediated mitophagy in yeast and mammalian systems
Q38282362Recovery of hibernating myocardium: what is the role of surgical revascularization?
Q88930712Redox Equivalents and Mitochondrial Bioenergetics
Q36646486Redox control of leukemia: from molecular mechanisms to therapeutic opportunities
Q37446110Redox signaling in cardiovascular health and disease.
Q28582920Reduced activity of mtTFA decreases the transcription in mitochondria isolated from diabetic rat heart
Q55172169Reduction of the ATPase inhibitory factor 1 (IF1) leads to visual impairment in vertebrates.
Q33208704Regulating cell survival by controlling cellular energy production: novel functions for ancient signaling pathways?
Q24296720Regulation of cytochrome c oxidase activity by c-Src in osteoclasts
Q33531334Regulation of metabolism in Caenorhabditis elegans longevity
Q38034936Regulation of metastasis; mitochondrial DNA mutations have appeared on stage
Q34119796Regulation of mitochondrial biogenesis
Q35213424Regulation of mitochondrial biogenesis in muscle by endurance exercise
Q53392996Relation of functional and morphological changes in mitochondria to myocardial contractile and relaxation reserves in asymptomatic to mildly symptomatic patients with hypertrophic cardiomyopathy.
Q37344137Renal angiotensin II type 1 receptor expression and associated hypertension in rats with minimal SHR nuclear genome
Q34167978Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias.
Q34583753Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA.
Q33873936Reproductive biotechnology and "big" biological questions
Q44195721Rescue of a mitochondrial deficiency causing Leber Hereditary Optic Neuropathy
Q39347930Resolution of mitochondrial oxidative stress rescues coronary collateral growth in Zucker obese fatty rats.
Q51766326Resolving the Enigma of the Clonal Expansion of mtDNA Deletions.
Q43207647Respiration in adipocytes is inhibited by reactive oxygen species
Q40601891Respiratory complex II defect in siblings associated with a symptomatic secondary block in fatty acid oxidation
Q43672495Restoration of Ca2+-inhibited oxidative phosphorylation in cardiac mitochondria by mitochondrial Ca2+ unloading
Q34662316Retinal Function and Structure in Ant1-Deficient Mice
Q49632281Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism.
Q34808624Retinal ganglion cell disorders: types and treatments
Q33805623Reverse genetic studies of mitochondrial DNA-based diseases using a mouse model
Q33705828Revolution in mitochondrial medicine
Q42369764Role of Cardiolipin in Mitochondrial Signaling Pathways
Q58599968Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer's Disease and CNS-Related Disorders
Q41070215Role of mitochondrial DNA damage and dysfunction in veterans with Gulf War Illness.
Q34976262Role of mitochondrial dysfunction in Alzheimer's disease
Q38824997Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases
Q35625434Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease
Q38917412Roles of mitophagy in cellular physiology and development
Q55007822Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Q34033183Rotenone remarkably attenuates oxidative stress, inflammation, and fibrosis in chronic obstructive uropathy
Q44840186SOCS2 inhibited mitochondria biogenesis via inhibiting p38 MAPK/ATF2 pathway in C2C12 cells
Q33822264SOD2 deficient erythroid cells up-regulate transferrin receptor and down-regulate mitochondrial biogenesis and metabolism
Q34049463SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration
Q38957347Schwann cell mitochondria as key regulators in the development and maintenance of peripheral nerve axons
Q44512801Screening and comparison of antioxidant activity of solvent extracts of herbal medicines used in Korea
Q88930281Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities
Q34363047Search for characteristic structural features of mammalian mitochondrial tRNAs.
Q33843176Secondary carnitine deficiency and impaired docosahexaenoic (22:6n-3) acid synthesis: a common denominator in the pathophysiology of diseases of oxidative phosphorylation and beta-oxidation
Q37066699Selection by drug resistance proteins located in the mitochondria of mammalian cells
Q45869262Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes
Q36777340Selective imaging of mitochondrial surfaces with novel fluorescent probes
Q47616286Sequence polymorphism in the coding region of mitochondrial genome encompassing position 8389-8865.
Q83047794Sequence polymorphisms of the mtDNA control region in a human isolate: the Georgians from Swanetia
Q35012267Sequence variation and the biological function of genes: methodological and biological considerations
Q43564487Sequence variations in the NDUFA1 gene encoding a subunit of complex I of the respiratory chain
Q50059988Sequencing and analysis of the whole genome of Indian Gujarati male.
Q46040648Sequencing and comparing whole mitochondrial genomes of animals
Q49920428Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Q35006906Sexual dimorphism in the expression of mitochondria-related genes in rat heart at different ages
Q64229710Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP
Q40394633Signal transduction to mitochondrial ATP synthase: evidence that PDGF-dependent phosphorylation of the delta-subunit occurs in several cell lines, involves tyrosine, and is modulated by lysophosphatidic acid
Q73205704Simultaneous detection of mitochondrial respiratory chain activity and reactive oxygen in digitonin-permeabilized cells using flow cytometry
Q51133421Simultaneous fluorescence visualization of mitochondrial hydrogen peroxide and zinc ions in live cells and in vivo.
Q28242165Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians
Q38137835Single-nucleotide polymorphisms of GPX1 and MnSOD and susceptibility to bladder cancer: a systematic review and meta-analysis
Q35420953Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction
Q34614061Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression
Q34739211So close and yet so far: mitochondria and peroxisomes are one but with specific talents.
Q46265496Social Origins of Developmental Risk for Mental and Physical Illness.
Q47862133Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours
Q79108457Somatic mitochondrial DNA mutations in adult-onset leukaemia
Q64134314Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer
Q37736575Species identification through mitochondrial rRNA genetic analysis.
Q30501631Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast
Q36069084Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development
Q36918606Specific polymorphic variation in the mitochondrial genome and increased in-hospital mortality after severe trauma
Q44489239Specific targeting of a DNA-alkylating reagent to mitochondria. Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide
Q57688071Specificity of mtDNA-directed PCR—influence of NUclear MTDNA insertion (NUMT) contamination in routine samples and techniques
Q49971097Spectral properties of ionic benzotristhiazole based donor-acceptor NLO-phores in polymer matrices and their one- and two-photon cellular imaging ability.
Q56689113Sperm Mitochondrial Mutations as a Cause of Low Sperm Motility
Q36414411Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase
Q35131099Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA.
Q27077073Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction
Q30451005Stem cell-based models and therapies for neurodegenerative diseases
Q34478955Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism.
Q28272479Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia
Q47667899Subcellular Fractionation for DIGE-Based Proteomics
Q37136773Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III.
Q28397283Sulfite Oxidase Activity of Cytochrome c: Role of Hydrogen Peroxide
Q44583900Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.
Q45857435Suppression of disease phenotypes of adult mito-mice carrying pathogenic mtDNA by bone marrow transplantation.
Q36642278Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis
Q34217027Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria
Q41352849Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting
Q34416995Surveyor Nuclease: a new strategy for a rapid identification of heteroplasmic mitochondrial DNA mutations in patients with respiratory chain defects.
Q36530909Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis
Q46438642Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.
Q42591986Synthesis of a mitochondria-targeted spin trap using a novel Parham-type cyclization.
Q41188746Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants
Q29617873Systematic screen for human disease genes in yeast
Q37030590Systematic screens for human disease genes, from yeast to human and back
Q92309378Systemic Lupus Erythematosus: Pathogenesis at the Functional Limit of Redox Homeostasis
Q34339371TAT opens the door
Q64883288TEFM regulates both transcription elongation and RNA processing in mitochondria.
Q38802165TUFM downregulation induces epithelial-mesenchymal transition and invasion in lung cancer cells via a mechanism involving AMPK-GSK3β signaling
Q48760407Tacrine and its analogues impair mitochondrial function and bioenergetics: a lipidomic analysis in rat brain.
Q51067188Targetable phosphorescent oxygen nanosensors for the assessment of tumor mitochondrial dysfunction by monitoring the respiratory activity.
Q43963405Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage.
Q55017371Targeting Mitochondrial Bioenergetics as a Therapeutic Strategy for Chronic Lymphocytic Leukemia.
Q38622293Targeting autophagy and mitophagy for mitochondrial diseases treatment.
Q46774788Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis
Q34264476Targeting large molecules to mitochondria
Q81110470Targeting of tRNA into yeast and human mitochondria: the role of anticodon nucleotides
Q37049208Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease
Q44624372Targeting proteins to mitochondria using TAT.
Q46453448Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMS II mutant lacking nad7.
Q43632344The (Holey) study of mitochondria in apoptosis
Q35137172The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging
Q36228346The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification
Q38945146The Mitochondrial Permeability Transition Pore and ATP Synthase.
Q34879429The Mitoscriptome in Aging and Disease.
Q24543580The PET1-CMS mitochondrial mutation in sunflower is associated with premature programmed cell death and cytochrome c release
Q90568414The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury
Q60695086The T9176G mutation of human mtDNA gives a fully assembled but inactive ATP synthase when modeled in Escherichia coli
Q28661634The Trojan female technique: a novel, effective and humane approach for pest population control
Q35127771The Use of Denaturing High-Performance Liquid Chromatography (DHPLC) for the Analysis of Genetic Variations: Impact for Diagnostics and Pharmacogenetics
Q35926921The absence of a mitochondrial genome in rho0 yeast cells extends lifespan independently of retrograde regulation
Q28754651The adaptive evolution of the mammalian mitochondrial genome
Q33826111The age-related accumulation of a mitochondrial DNA control region mutation in muscle, but not brain, detected by a sensitive PNA-directed PCR clamping based method
Q24618241The complete sequence of the zebrafish (Danio rerio) mitochondrial genome and evolutionary patterns in vertebrate mitochondrial DNA
Q33655973The costs of being male: are there sex-specific effects of uniparental mitochondrial inheritance?
Q36470441The creation of cybrids harboring mitochondrial haplogroups in the Taiwanese population of ethnic Chinese background: an extensive in vitro tool for the study of mitochondrial genomic variations
Q35083432The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells
Q34380418The effect of citrulline and arginine supplementation on lactic acidemia in MELAS syndrome
Q42427505The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism
Q39625453The effects of antidepressants on mitochondrial function in a model cell system and isolated mitochondria.
Q44651953The effects of nuclear reprogramming on mitochondrial DNA replication.
Q33904974The emergence of modern neuroscience: some implications for neurology and psychiatry
Q38866179The evolution and role of mitochondrial fusion and fission in aging and disease
Q55039234The evolutionary processes of mitochondrial and chloroplast genomes differ from those of nuclear genomes.
Q35948562The formation and functional consequences of heterogeneous mitochondrial distributions in skeletal muscle
Q34237999The genetics and pathology of oxidative phosphorylation
Q37142417The genetics you never knew: a genetics primer
Q24291646The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders
Q34974582The importance of mitochondrial DNA in aging and cancer
Q39182036The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(II) asymmetric complexes
Q73179332The inheritance of mitochondrial DNA heteroplasmy: random drift, selection or both?
Q24623671The innate immune system in host mice targets cells with allogenic mitochondrial DNA
Q24546038The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
Q37651211The mitochondrial DNA polymerase in health and disease.
Q33813322The mitochondrial T16189C polymorphism is associated with coronary artery disease in Middle European populations
Q34442309The mitochondrial genome and mitochondrial muscle disorders.
Q38034189The mitochondrial genome and psychiatric illness
Q28681826The mitochondrial genome encodes abundant small noncoding RNAs
Q36844086The mitochondrial genome sequence of Mus terricolor: comparison with Mus musculus domesticus and implications for xenomitochondrial mouse modeling.
Q22010971The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance
Q80761703The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy
Q30480776The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis
Q43873241The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats
Q36693924The mitochondrion as a primary site of action of regulatory agents involved in neuroimmunomodulation.
Q33829445The molecular diagnosis of metabolic myopathies
Q37684132The multiple mechanisms of cell death triggered by resveratrol in lymphoma and leukemia
Q34338783The neuro-ophthalmology of mitochondrial disease
Q33870484The neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass.
Q43887789The nuclear genome is involved in heteroplasmy control in a mitochondrial mutant strain of Drosophila subobscura
Q34562809The organization and inheritance of the mitochondrial genome
Q35647363The potential risks of abnormal transmission of mtDNA through assisted reproductive technologies.
Q37418894The power of yeast to model diseases of the powerhouse of the cell.
Q93000726The primitive growth factor NME7AB induces mitochondrially active naïve-like pluripotent stem cells
Q27653963The proteome of Saccharomyces cerevisiae mitochondria
Q35019244The role of maternal mitochondria during oogenesis, fertilization and embryogenesis
Q37606811The role of mitochondria in health and disease
Q37878430The role of mitochondria in neurodegenerative diseases
Q37825773The role of mitochondria in osteoarthritis
Q35174458The role of mitochondria in the life of the nematode, Caenorhabditis elegans
Q36910241The role of mitochondrial DNA mutations and free radicals in disease and ageing
Q34327375The role of mitochondrial genome in essential hypertension in a Chinese Han population
Q28509993The role of mitochondrial porins and the permeability transition pore in learning and synaptic plasticity
Q24595895The role of the TIM8-13 complex in the import of Tim23 into mitochondria
Q34591630The role of the mitochondrial genome in ageing and carcinogenesis
Q89791052The spatio-temporal features of chicken mitochondrial ND2 gene heteroplasmy and the effects of nutrition factors on this gene
Q33927048The strength and timing of the mitochondrial bottleneck in salmon suggests a conserved mechanism in vertebrates
Q38152284The systems biology of mitochondrial fission and fusion and implications for disease and aging
Q48328769The typically mitochondrial DNA-encoded ATP6 subunit of the F1F0-ATPase is encoded by a nuclear gene in Chlamydomonas reinhardtii
Q37915809The use of individual patient's fibroblasts in the search for personalized treatment of nuclear encoded OXPHOS diseases.
Q36707801The use of micromanipulation methods as a tool to prevention of transmission of mutated mitochondrial DNA.
Q40663427The yeast counterparts of human 'MELAS' mutations cause mitochondrial dysfunction that can be rescued by overexpression of the mitochondrial translation factor EF-Tu.
Q38793825Therapeutic Potential of Resveratrol in Lymphoid Malignancies.
Q59793891Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency
Q36505451Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes
Q45230300Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging
Q40420581To use MIBI or not to use MIBI? That is the question when assessing tumour cells
Q28649774Toward a mtDNA locus-specific mutation database using the LOVD platform
Q34265156Towards mitochondrial gene therapy: DQAsomes as a strategy
Q44428732Towards understanding human mitochondrial leucine aminoacylation identity.
Q51126217Toxicity of new emerging pollutant tris-(2,3-dibromopropyl) isocyanurate on BALB/c mice.
Q36633152Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.
Q43138065Trading mtDNA uncovers its role in metastasis.
Q51686616Transcription factors c-Jun/activator protein-1 and nuclear factor-kappa B in oxidative stress response in mitochondrial diseases.
Q35923008Transcriptional control of cardiac fuel metabolism and mitochondrial function
Q37030759Transcriptional quiescence of paternal mtDNA in cyprinid fish embryos
Q24532032Transformation of isolated mammalian mitochondria by bacterial conjugation
Q37358162Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction
Q52115273Transmission of the mitochondrial t8993c mutation in a new family.
Q37612665Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene
Q35912030Transmitochondrial mice: proof of principle and promises
Q24200432Treatment for mitochondrial disorders
Q24244543Treatment for mitochondrial disorders
Q24247852Treatment for mitochondrial myopathy
Q46489599Troxerutin attenuates diet-induced oxidative stress, impairment of mitochondrial biogenesis and respiratory chain complexes in mice heart
Q36619848Two-dimensional intact mitochondrial DNA agarose electrophoresis reveals the structural complexity of the mammalian mitochondrial genome.
Q30833030Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein
Q52319318Tying Trafficking to Fusion and Fission at the Mighty Mitochondria.
Q52971206Tyrosine-derived stimuli responsive, fluorescent amino acids.
Q40218393UV-irradiation induces oxidative damage to mitochondrial DNA primarily through hydrogen peroxide: analysis of 8-oxodGuo by HPLC.
Q50488724UVB irradiation as a tool to assess ROS-induced damage in human spermatozoa.
Q35004513Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage
Q37049152Ultrastructural definition of apoptosis in heart failure
Q44530003Ultrastructure of the gingiva in cardiac patients treated with or without calcium channel blockers
Q42733812Uncoupling protein 1 decreases superoxide production in brown adipose tissue mitochondria
Q34035403Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages
Q37198638Unique quadruple immunofluorescence assay demonstrates mitochondrial respiratory chain dysfunction in osteoblasts of aged and PolgA(-/-) mice
Q33567299Up-regulation of avian uncoupling protein in cold-acclimated and hyperthyroid ducklings prevents reactive oxygen species production by skeletal muscle mitochondria
Q46555077Upregulation of matrix metalloproteinase 1 and disruption of mitochondrial network in skin fibroblasts of patients with MERRF syndrome
Q27940072Uracil-DNA glycosylase-deficient yeast exhibit a mitochondrial mutator phenotype
Q45297227Usage of mitochondrial D-loop variation to predict risk for Huntington disease.
Q46160383Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells
Q42036779Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia
Q36309165Variations of mitochondrial D-loop region plus downstream gene 1 2S rRNA-tRNA(phe) and gastric carcinomas
Q38714209Viral symbiosis and the holobiontic nature of the human genome
Q37676789Vitrification of in vitro matured oocytes: effects on meiotic spindle configuration and mitochondrial function
Q33655960What cost mitochondria? The maintenance of functional mitochondrial DNA within and across generations.
Q64228827When a common biological role does not imply common disease outcomes: Disparate pathology linked to human mitochondrial aminoacyl-tRNA synthetases
Q29615672Why do we age?
Q34422404Xenomitochondrial mice: investigation into mitochondrial compensatory mechanisms
Q34136226Yeast mitochondrial dynamics: fusion, division, segregation, and shape
Q73587274[Mitochondrial diseases: still a difficult diagnosis]
Q48165533iPSCs, a Future Tool for Therapeutic Intervention in Mitochondrial Disorders: Pros and Cons.
Q37164369miRNAs in mtDNA-less cell mitochondria
Q34101830mtDNA haplogroup J modulates telomere length and nitric oxide production
Q34574948mtDNA phylogeny and evolution of laboratory mouse strains
Q35875202mtDNA variation, climatic adaptation, degenerative diseases, and longevity
Q34318143tRNA and cytochrome c in cell death and beyond.
Q26740355Generation of reactive oxygen species in the anterior eye segment. Synergistic codrugs of N-acetylcarnosine lubricant eye drops and mitochondria-targeted antioxidant act as a powerful therapeutic platform for the treatment of cataracts and primary o

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