scholarly article | Q13442814 |
P50 | author | Johannes N Spelbrink | Q40021713 |
Daniel L. Kaplan | Q41785009 | ||
Jean-Louis Mergny | Q42434391 | ||
P2093 | author name string | Jun Zhou | |
Joshua A Sommers | |||
Robert M Brosh | |||
Sanjay Kumar Bharti | |||
P2860 | cites work | Novel mitochondrial DNA deletion found in a renal cell carcinoma | Q71598964 |
Spectrum of mitochondrial DNA rearrangements in the Pearson marrow-pancreas syndrome | Q71793775 | ||
Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues | Q73341946 | ||
Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase | Q77948758 | ||
Large deletions in mitochondrial DNA in radiation-associated human thyroid tumors | Q78598229 | ||
Mitochondrial DNA and disease | Q85076246 | ||
Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13 | Q21144902 | ||
Premature ageing in mice expressing defective mitochondrial DNA polymerase | Q24294365 | ||
G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA | Q24303584 | ||
Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates | Q24312975 | ||
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein | Q24316108 | ||
Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA | Q24563813 | ||
Thermal difference spectra: a specific signature for nucleic acid structures. | Q24812851 | ||
Mechanism of homologous recombination and implications for aging-related deletions in mitochondrial DNA | Q27012566 | ||
Mitochondrial genome changes and neurodegenerative diseases | Q27023750 | ||
Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers | Q27654041 | ||
Aging: a theory based on free radical and radiation chemistry | Q27860549 | ||
Sequence and organization of the human mitochondrial genome | Q27860659 | ||
Pif1 family helicases suppress genome instability at G-quadruplex motifs | Q27932667 | ||
Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity | Q28118339 | ||
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma | Q28249725 | ||
The G4 genome | Q28289973 | ||
Deletions of mitochondrial DNA in Kearns-Sayre syndrome | Q28297900 | ||
Mitochondrial diseases in man and mouse | Q29614555 | ||
Mitochondria and cancer | Q29616610 | ||
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease | Q29619113 | ||
Interaction of human DNA topoisomerase I with G-quartet structures | Q30635800 | ||
Following G-quartet formation by UV-spectroscopy | Q32012738 | ||
Deleted mitochondrial DNA in the skeletal muscle of aged individuals | Q67825576 | ||
Detection of mitochondrial DNA deletions in the cochlea and its structural elements from archival human temporal bone tissue | Q33317872 | ||
Processing of G4 DNA by Dna2 helicase/nuclease and replication protein A (RPA) provides insights into the mechanism of Dna2/RPA substrate recognition | Q33348184 | ||
G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae | Q33646754 | ||
Human mitochondrial topoisomerase I | Q33943662 | ||
Structure and function of hexameric helicases. | Q34019405 | ||
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae | Q34020165 | ||
G‐quadruplex nucleic acids and human disease | Q34073316 | ||
G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation | Q34136604 | ||
Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China | Q34170799 | ||
Defects in mitochondrial DNA replication and human disease | Q34241192 | ||
Mitochondrial DNA deletions are associated with non-B DNA conformations | Q34278779 | ||
Directly repeated sequences associated with pathogenic mitochondrial DNA deletions | Q34313597 | ||
An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs. | Q34337096 | ||
Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers | Q35015881 | ||
mtDNA Mutations and Their Role in Aging, Diseases and Forensic Sciences | Q35059486 | ||
Progressive external ophthalmoplegia characterized by multiple deletions of mitochondrial DNA: unraveling the pathogenesis of human mitochondrial DNA instability and the initiation of a genetic classification | Q35166737 | ||
Transcription and translation of deleted mitochondrial genomes in Kearns-Sayre syndrome: implications for pathogenesis | Q35197862 | ||
Mitochondrial DNA and human thyroid diseases | Q35837991 | ||
Deletions of the mitochondrial genome | Q35848675 | ||
DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase. | Q35860068 | ||
Two direct repeats cause most human mtDNA deletions | Q35864144 | ||
The interface of transcription and DNA replication in the mitochondria | Q35907097 | ||
Recombination via flanking direct repeats is a major cause of large-scale deletions of human mitochondrial DNA. | Q35907687 | ||
Human mitochondrial DNA helicase TWINKLE is both an unwinding and annealing helicase | Q35922647 | ||
DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion | Q36003726 | ||
The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function | Q36052367 | ||
RETRACTED: In vivo and in vitro evidence for slipped mispairing in mammalian mitochondria | Q36483459 | ||
A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence | Q36567341 | ||
Mutations in DNA2 link progressive myopathy to mitochondrial DNA instability | Q36595107 | ||
The role of mitochondria in aging | Q36638140 | ||
FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability | Q36710804 | ||
Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase | Q36855814 | ||
The relationship of Parkinson disease with aging | Q36936656 | ||
DNA secondary structures: stability and function of G-quadruplex structures | Q37051064 | ||
What causes mitochondrial DNA deletions in human cells? | Q37096545 | ||
The yeast nuclear gene suv3 affecting mitochondrial post-transcriptional processes encodes a putative ATP-dependent RNA helicase | Q37122753 | ||
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo | Q37168915 | ||
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability | Q37201282 | ||
Circular dichroism and conformational polymorphism of DNA. | Q37384531 | ||
In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands | Q37528801 | ||
The generation of mitochondrial DNA large-scale deletions in human cells. | Q37922086 | ||
Visualizing the quadruplex: from fluorescent ligands to light-up probes | Q38034133 | ||
G-quadruplex-induced instability during leading-strand replication | Q38967736 | ||
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication | Q39069898 | ||
Helicase and polymerase move together close to the fork junction and copy DNA in one-nucleotide steps | Q39226842 | ||
A case of Kearns-Sayre syndrome with two novel deletions (9.768 and 7.253 kb) of the mtDNA associated with the common deletion in blood leukocytes, buccal mucosa and hair follicles | Q39256329 | ||
Mitochondrial diabetes mellitus: a review | Q40437302 | ||
Distribution of the 9-bp mitochondrial DNA region V deletion among North American Indians. | Q40656009 | ||
A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop | Q41517167 | ||
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase | Q41769196 | ||
G-quadruplex structures are stable and detectable in human genomic DNA. | Q41847291 | ||
Mitochondrial DNA deletions serve as biomarkers of aging in the skin, but are typically absent in nonmelanoma skin cancers | Q42676472 | ||
QuadBase: genome-wide database of G4 DNA--occurrence and conservation in human, chimpanzee, mouse and rat promoters and 146 microbes | Q43033108 | ||
The N-terminal domain of TWINKLE contributes to single-stranded DNA binding and DNA helicase activities | Q43042722 | ||
Nature of mitochondrial DNA deletions in substantia nigra neurons | Q43058638 | ||
Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments | Q43220425 | ||
DnaB drives DNA branch migration and dislodges proteins while encircling two DNA strands. | Q44199583 | ||
Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected]. | Q45852433 | ||
Significant existence of deleted mitochondrial DNA in cirrhotic liver surrounding hepatic tumor | Q46466427 | ||
Mitochondrial DNA variation and the origins of the Aleuts. | Q47309387 | ||
Transcription of deleted mitochondrial DNA in human colon adenocarcinoma cells | Q48171774 | ||
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. | Q48588748 | ||
Deletion of mitochondrial DNA in patients with combined features of Kearns-Sayre and MELAS syndromes. | Q48713162 | ||
Genotype and phenotype analyses in 136 patients with single large-scale mitochondrial DNA deletions. | Q51891859 | ||
The S. cerevisiae nuclear gene SUV3 encoding a putative RNA helicase is necessary for the stability of mitochondrial transcripts containing multiple introns. | Q52518138 | ||
Effect of monovalent cations and G-quadruplex structures on the outcome of intramolecular homologous recombination. | Q54479743 | ||
Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity | Q56552038 | ||
Detection of G-quadruplex DNA in mammalian cells | Q57756171 | ||
Deletions of mitochondrial DNA in Kearns-Sayre syndrome and ocular myopathies: Genetic, biochemical and morphological studies | Q61797405 | ||
Site-specific deletions of the mitochondrial genome in the Pearson marrow-pancreas syndrome | Q63681446 | ||
Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion | Q67482157 | ||
Multiple short direct repeats associated with single mtDNA deletions | Q67503198 | ||
P433 | issue | 43 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mitochondrial DNA | Q27075 |
mitochondrion | Q39572 | ||
P304 | page(s) | 29975-29993 | |
P577 | publication date | 2014-09-05 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase | |
P478 | volume | 289 |
Q95841103 | "Mitochondrial Toolbox" - A Review of Online Resources to Explore Mitochondrial Genomics |
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Q47902770 | A Role for Non-B DNA Forming Sequences in Mediating Microlesions Causing Human Inherited Disease |
Q57991440 | A common pattern of DNase I footprinting throughout the human mtDNA unveils clues for a chromatin-like organization |
Q35576164 | A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands |
Q37065777 | Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING. |
Q35723527 | Borrowing nuclear DNA helicases to protect mitochondrial DNA. |
Q92147311 | Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes |
Q61795898 | Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions |
Q41183468 | DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol |
Q57808238 | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress |
Q64267809 | Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid⁻Protein Interaction |
Q36337650 | Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agents. |
Q92827521 | Enrichment of G4DNA and a Large Inverted Repeat Coincide in the Mitochondrial Genomes of Termitomyces |
Q39638326 | Evidence That G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress. |
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