Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease

scientific article

Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1989PNAS...86.1382B
P356DOI10.1073/PNAS.86.4.1382
P932PMC publication ID286694
P698PubMed publication ID2784006
P5875ResearchGate publication ID20372251

P2093author name stringU Hedner
J B Garris
K M Brinkhous
M S Read
V Diness
P2860cites workTissue factor and hemostasisQ28630773
Amino acid sequence and posttranslational modifications of human factor VIIa from plasma and transfected baby hamster kidney cellsQ28646327
Characterization of a cDNA coding for human factor VIIQ28646329
Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulationQ33647003
Effect of antihemophilic factor on one-stage clotting tests; a presumptive test for hemophilia and a simple one-stage antihemophilic factor assy procedureQ34232161
Purification and properties of human coagulation factor VII.Q34285207
Prevention of occlusive coronary artery thrombosis by a murine monoclonal antibody to porcine von Willebrand factorQ34366855
An alternative extrinsic pathway of human blood coagulation.Q34715607
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulationQ35047906
Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitorsQ36990492
Purified human factor VIII procoagulant protein: comparative hemostatic response after infusions into hemophilic and von Willebrand disease dogsQ37559120
Tissue factor-initiated blood coagulationQ40168938
Tissue factor revisited.Q40253416
Pathophysiology of platelet-aggregating von Willebrand factor: applications of the venom coagglutinin vWF assayQ40312861
Altered factor VII activity in hemophiliaQ41495913
Activated factor VII: presence in factor IX concentrates and persistence in the circulation after infusionQ41545752
The inhibition of activated bovine coagulation factors X and VII by antithrombin III.Q43458224
Initiation of the extrinsic pathway of coagulation. Association of factor VIIa with a cell line expressing tissue factorQ43658573
The esterase activity of coagulation factor VII. Evidence for intrinsic activity of the zymogenQ44691907
Expression and linkage of genes for X-linked hemophilias A and B in the dogQ45856212
Activated prothrombin concentrate for patients with factor VIII inhibitorsQ45856551
Efficacy of prothrombin-complex concentrates in hemophiliacs with antibodies to factor VIII: a multicenter therapeutic trialQ45863685
A canine model of hemophilic (factor VIII:C deficiency) bleedingQ45864385
An inhibitory monoclonal antibody against human tissue factorQ48224968
Monoclonal antibodies against bovine tissue factor, which block interaction with factor VIIa.Q48478286
Interaction of tissue factor and factor VII at the earliest phase of coagulationQ51261558
The effect of antithrombin III on the activity of the coagulation factors VII, IX and XQ66705587
Evidence for tissue factor-dependent activation of the classic extrinsic coagulation mechanism in blood obtained from bleeding time woundsQ68273350
Effect of calcium ion concentration on the ability of fibrinogen and von Willebrand factor to support the ADP-induced aggregation of human plateletsQ68826461
von Willebrand diseaseQ70321843
The development and characterisation of antibodies to human factor VIII in haemophilic dogsQ70361308
Venom coagglutinin for detection of von Willebrand factor activity in animal plasmasQ70981710
Use of venom coagglutinin and lyophilized platelets in testing for platelet-aggregating von Willebrand factorQ72073463
Ethanol Gelation: A Rapid Screening Test for Intravascular CoagulationQ72229166
Determination of fibrinogen and fibrinogenolytic activityQ79452693
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecthemophiliaQ134003
hemophilia AQ2092064
hemophilia BQ2562598
P304page(s)1382-1386
P577publication date1989-02-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleEffect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease
P478volume86

Reverse relations

cites work (P2860)
Q30442996A review of current methods for assessing hemostasis in vivo and introduction to a potential alternative approach
Q30443003ARFI ultrasound monitoring of hemorrhage and hemostasis in vivo in canine von Willebrand disease and hemophilia
Q45877085Activated factor VII: my story
Q38235951Advances in bypassing agent therapy for hemophilia patients with inhibitors to close care gaps and improve outcomes
Q27012571Animal models of hemophilia
Q37091290Animal models of hemophilia and related bleeding disorders
Q34326780Canine hemophilia B resulting from a point mutation with unusual consequences
Q45889662Change of antigenic and neutralizing specificity in substitutional epitope peptides of hemophilia B inhibitor
Q45859525Characterization of canine coagulation factor VII and its complex formation with tissue factor: canine-human cross-species compatibility.
Q33584641Clinical use of recombinant FVIIa (rFVIIa).
Q37332201Complications of hemophilia A treatment: factor VIII inhibitors
Q45866368Epitope mapping of human factor IX inhibitor antibodies
Q45866981Gene Therapy for Hemophilia B: Host Immunosuppression Prolongs the Therapeutic Effect of Adenovirus-Mediated Factor IX Expression
Q36337979Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo
Q45865821In vivo bypass of hemophilia A coagulation defect by factor XIIa implant
Q35109095In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs
Q37056724In vivo models of haemophilia - status on current knowledge of clinical phenotypes and therapeutic interventions
Q43615162Induction of acquired factor IX inhibitors in cynomolgus monkey (Macaca fascicularis): a new primate model of hemophilia B.
Q37570030Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin.
Q30409863Lessons Learned from Animal Models of Inherited Bleeding Disorders
Q33802667Long-term expression of canine FVIIa in hemophilic dogs
Q36532500Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality
Q37277251N-/O-glycosylation analysis of human FVIIa produced in the milk of transgenic rabbits
Q37778292Optimal use of recombinant factor VIIa in the control of bleeding episodes in hemophilic patients
Q37586365Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog.
Q42139651Poly-N-acetylglucosamine fibers amplify the effectiveness of recombinant factor VIIA on clot formation in hemophilia B canine blood
Q36284643Preclinical trauma studies of recombinant factor VIIa
Q33490246Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion
Q35006608Prevention of spontaneous bleeding in dogs with haemophilia A and haemophilia B.
Q45881284Prolonged recombinant activated factor VII (rFVIIa) treatment for severe bleeding in a factor-IX-deficient patient with an inhibitor
Q35006603Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency
Q40901543Recombinant activated factor VII in the treatment of bleeding episodes in patients with inherited and acquired bleeding disorders.
Q38527508Recombinant activated factor VII: 30 years of research and innovation
Q34078730Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model
Q39262923Ribavirin-induced intracellular GTP depletion activates transcription elongation in coagulation factor VII gene expression.
Q37162830Successful treatment of canine hemophilia by continuous expression of canine FVIIa
Q30745198The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion
Q33982533The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate
Q39611127The influence of coagulation and inflammation research on the improvement of polytrauma care
Q38176103Traumatic coagulopathy--part 2: Resuscitative strategies
Q90858007Treatment and prevention of bleeding in congenital hemophilia A patients with inhibitors

Search more.