Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.

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Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200909175
P932PMC publication ID2867314
P698PubMed publication ID20439997
P5875ResearchGate publication ID44570892

P50authorJoachim GoedhartQ48081334
Daniel O WarmerdamQ62131443
Thomas HöferQ37380437
Antonio Z PolitiQ41045113
P2093author name stringWim Vermeulen
Roel van Driel
Martijn S Luijsterburg
Audrey M Gourdin
Martijn J Moné
Gesa von Bornstaedt
P2860cites workDynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cellsQ21146056
The xeroderma pigmentosum group C protein complex XPC-HR23B plays an important role in the recruitment of transcription factor IIH to damaged DNAQ22253377
Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosomeQ24290949
Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repairQ24304166
Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repairQ24312736
XPG endonuclease makes the 3' incision in human DNA nucleotide excision repairQ24320768
Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonucleaseQ24321351
Versatile DNA damage detection by the global genome nucleotide excision repair protein XPCQ24321461
Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanningQ24321848
Nuclear dynamics of PCNA in DNA replication and repairQ24534946
Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High SpecificityQ24563898
Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombeQ24629606
The comings and goings of nucleotide excision repair factors on damaged DNAQ24672395
Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3Q24673129
Recognition of DNA damage by the Rad4 nucleotide excision repair proteinQ27648368
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPAQ27648846
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent proteinQ27861056
Genome maintenance mechanisms for preventing cancerQ28131737
Proliferating cell nuclear antigen is required for DNA excision repairQ28182009
Human replication protein A binds single-stranded DNA in two distinct complexesQ28610087
Sequential assembly of the nucleotide excision repair factors in vivoQ28610121
DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repairQ28628567
Recombinant replication protein A: expression, complex formation, and functional characterizationQ29615758
DNA replication fidelityQ29616841
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factorQ29619833
Photoconversion in orange and red fluorescent proteinsQ30487323
Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesionsQ30974742
The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assayQ31060206
The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions.Q31157514
Order of assembly of human DNA repair excision nucleaseQ31326797
Ordered conformational changes in damaged DNA induced by nucleotide excision repair factorsQ33198588
DNA damage stabilizes interaction of CSB with the transcription elongation machineryQ33204356
Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repairQ33234407
The protein shuffle. Sequential interactions among components of the human nucleotide excision repair pathwayQ33240307
An aromatic sensor with aversion to damaged strands confers versatility to DNA repairQ33278102
Nature of DNA repair synthesis resistant to inhibitors of polymerase alpha in human cellsQ41572109
Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F.Q41679266
The dynamic range of transcriptionQ42069603
Local UV-induced DNA damage in cell nuclei results in local transcription inhibitionQ42512985
Three nonsense mutations responsible for group A xeroderma pigmentosumQ42805018
A mechanism for coordinating chromatin modification and preinitiation complex assembly.Q45947044
Cyan and yellow super fluorescent proteins with improved brightness, protein folding, and FRET Förster radiusQ48087580
Mathematical modeling of nucleotide excision repair reveals efficiency of sequential assembly strategies.Q51814227
Rapid switching of TFIIH between RNA polymerase I and II transcription and DNA repair in vivo.Q51841369
DNA repair endonuclease activity during synchronous growth of diploid human fibroblastsQ52480216
New Histone Incorporation Marks Sites of UV Repair in Human CellsQ63383593
The localization of ultraviolet-induced excision repair in the nucleus and the distribution of repair events in higher order chromatin loops in mammalian cellsQ68773610
Distribution and repair of bipyrimidine photoproducts in solar UV-irradiated mammalian cells. Possible role of Dewar photoproducts in solar mutagenesisQ73825736
Xeroderma pigmentosum complementation group A protein is driven to nucleotide excision repair sites by the electrostatic potential of distorted DNA.Q33296390
A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreadingQ33299082
Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.Q33310274
Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter.Q33316440
UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cellsQ33424219
Action of DNA repair endonuclease ERCC1/XPF in living cellsQ33861651
Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B.Q33953079
Interactions of DNA helicases with damaged DNA: possible biological consequencesQ34011942
A kinetic framework for a mammalian RNA polymerase in vivoQ34160479
Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.Q34383546
Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.Q34652298
Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific mannerQ34654453
Crosstalk between histone modifications during the DNA damage response.Q34973824
Mechanisms of DNA damage recognition and strand discrimination in human nucleotide excision repairQ35893372
Molecular mechanisms of mammalian global genome nucleotide excision repair.Q36389623
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.Q36697936
Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA.Q36699598
Modulation of RNA polymerase assembly dynamics in transcriptional regulationQ36739839
Beyond the sequence: cellular organization of genome functionQ36744492
Mechanism of open complex and dual incision formation by human nucleotide excision repair factorsQ36888668
In vivo dynamics of RNA polymerase II transcription.Q37088096
Direct measurement of association and dissociation rates of DNA binding in live cells by fluorescence correlation spectroscopy.Q37263417
Assembly of multiprotein complexes that control genome functionQ37427199
In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repairQ37619279
Adaptive enhancement and kinetics of nucleotide excision repair in humansQ38319312
Characterization of ERCC3 mutations in the Chinese hamster ovary 27-1, UV24 and MMC-2 cell linesQ38321404
Reaction mechanism of human DNA repair excision nucleaseQ38359257
Recruitment of the nucleotide excision repair endonuclease XPG to sites of UV-induced dna damage depends on functional TFIIH.Q39127506
Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivoQ39927746
Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblastsQ40805549
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P1104number of pages19
P304page(s)445-463
P577publication date2010-05-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleStochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair
P478volume189

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