| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1990PNAS...87.8080H |
| P356 | DOI | 10.1073/PNAS.87.20.8080 |
| P932 | PMC publication ID | 54896 |
| P698 | PubMed publication ID | 2236020 |
| P5875 | ResearchGate publication ID | 20920092 |
| P50 | author | Robert Gallo | Q469904 |
| P2093 | author name string | Franchini G | |
| Hattori N | |||
| Fargnoli K | |||
| Marcon L | |||
| Michaels F | |||
| P2860 | cites work | Sequence of a novel simian immunodeficiency virus from a wild-caught African mandrill | Q45842896 |
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| An African primate lentivirus (SIVsm) closely related to HIV-2. | Q48295012 | ||
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| Seroepidemiologic survey of captive Old-World primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys). | Q55243599 | ||
| Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR | Q68097623 | ||
| Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
| Detection of specific sequences among DNA fragments separated by gel electrophoresis | Q25939003 | ||
| Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase | Q26778389 | ||
| Rapid and efficient site-specific mutagenesis without phenotypic selection | Q27860628 | ||
| Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS | Q29614260 | ||
| The role of mononuclear phagocytes in HTLV-III/LAV infection | Q29618676 | ||
| Clinical, hematologic, and immunologic cross-sectional evaluation of individuals exposed to human immunodeficiency virus type-2 (HIV-2). | Q30404166 | ||
| The genome organization of STLV-3 is similar to that of the AIDS virus except for a truncated transmembrane protein | Q30405844 | ||
| Genetic variability between isolates of human immunodeficiency virus (HIV) type 2 is comparable to the variability among HIV type 1. | Q33639547 | ||
| Human immunodeficiency virus type 1 negative factor is a transcriptional silencer | Q33836630 | ||
| Molecular and biological characterization of a replication competent human immunodeficiency type 2 (HIV-2) proviral clone | Q33848331 | ||
| Isolation of a lentivirus from a macaque with lymphoma: comparison with HTLV-III/LAV and other lentiviruses. | Q33927613 | ||
| Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity | Q33929164 | ||
| Isolation of a new human retrovirus from West African patients with AIDS. | Q34038984 | ||
| Genome organization and transactivation of the human immunodeficiency virus type 2. | Q34048704 | ||
| Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys | Q34162184 | ||
| Identification of HIV-1 vpr product and function | Q34168026 | ||
| Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1. | Q34323971 | ||
| Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor | Q34323995 | ||
| Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication | Q34603122 | ||
| Extensive genetic variability of simian immunodeficiency virus from African green monkeys | Q35131842 | ||
| Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys). | Q35617653 | ||
| The effect of helper virus on Abelson virus-induced transformation of lymphoid cells | Q36340152 | ||
| Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses | Q36470925 | ||
| Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. | Q36487565 | ||
| Persistent infection of rhesus macaques with a molecular clone of human immunodeficiency virus type 2: evidence of minimal genetic drift and low pathogenetic effects | Q36783146 | ||
| Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells. | Q36829615 | ||
| Identification of a novel retroviral gene unique to human immunodeficiency virus type 2 and simian immunodeficiency virus SIVMAC. | Q36872683 | ||
| Mutational analysis of the human immunodeficiency virus vpr open reading frame. | Q40116997 | ||
| The simian immunodeficiency virus envelope open reading frame located after the termination codon is expressed in vivo in infected animals | Q42654446 | ||
| A novel gene of HIV-1, vpu, and its 16-kilodalton product | Q42656133 | ||
| Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2. | Q42658314 | ||
| Sequence of simian immunodeficiency virus and its relationship to the human immunodeficiency viruses | Q45831194 | ||
| Sequence of simian immunodeficiency virus from African green monkey, a new member of the HIV/SIV group | Q45832109 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | macrophage | Q184204 |
| P304 | page(s) | 8080-8084 | |
| P577 | publication date | 1990-10-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages | |
| P478 | volume | 87 |
| Q35853370 | A conserved LXXLF sequence is the major determinant in p6gag required for the incorporation of human immunodeficiency virus type 1 Vpr. |
| Q33824939 | A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm) |
| Q34501320 | A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects. |
| Q35850368 | A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles |
| Q36650619 | Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages |
| Q33795939 | Cell cycle-regulated transcription by the human immunodeficiency virus type 1 Tat transactivator |
| Q40048199 | Context-dependent role of human immunodeficiency virus type 1 auxiliary genes in the establishment of chronic virus producers. |
| Q24541155 | Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR |
| Q45755783 | Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1. |
| Q36672092 | Discovery and in vitro development of AIDS antiviral drugs as biopharmaceuticals |
| Q36701891 | Dispensable role of the human immunodeficiency virus type 2 Vpx protein in viral replication |
| Q36698525 | Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants |
| Q33936492 | Effect of reciprocal complementation of two defective human immunodeficiency virus type 1 (HIV-1) molecular clones on HIV-1 cell tropism and virulence |
| Q24540298 | Envelope glycoprotein cytoplasmic domains from diverse lentiviruses interact with the prenylated Rab acceptor |
| Q33784321 | Evolution of syncytium-inducing and non-syncytium-inducing biological virus clones in relation to replication kinetics during the course of human immunodeficiency virus type 1 infection. |
| Q33938392 | Evolution of the primate lentiviruses: evidence from vpx and vpr |
| Q35832979 | Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency. |
| Q35846506 | Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr |
| Q37056955 | Genetic regulation of human immunodeficiency virus. |
| Q36370102 | HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells |
| Q37689513 | HIV-1 Vpr-a still "enigmatic multitasker". |
| Q37029922 | HIV-1 Vpr: mechanisms of G2 arrest and apoptosis |
| Q34957142 | HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention |
| Q36661976 | HIV-1 infection of mononuclear phagocytic cells: the case for bacterial innate immune deficiency in AIDS. |
| Q39009412 | HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle |
| Q44405088 | HIV-1 viral protein R compromises cellular immune function in vivo |
| Q45782813 | Host virus interactions and the molecular regulation of HIV-1: role in the pathogenesis of HIV-associated nephropathy |
| Q24523263 | Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) interacts with Lys-tRNA synthetase: implications for priming of HIV-1 reverse transcription |
| Q24685157 | Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B |
| Q38609782 | Human immunodeficiency virus type 1 Vpr binds to the N lobe of the Wee1 kinase domain and enhances kinase activity for CDC2 |
| Q39880367 | Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest |
| Q36484133 | Human immunodeficiency virus type 1 Vpr induces cell cycle G2 arrest through Srk1/MK2-mediated phosphorylation of Cdc25 |
| Q36400526 | Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages |
| Q40935057 | Human immunodeficiency virus type 1 Vpr modifies cell proliferation via multiple pathways |
| Q35077587 | Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells |
| Q36654319 | Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions |
| Q24674793 | Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard |
| Q37633631 | Human immunodeficiency viruses regulated by alternative trans-activators: genetic evidence for a novel non-transcriptional function of Tat in virion infectivity. |
| Q37476959 | Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes |
| Q36820705 | Identification of viral determinants of macrophage tropism for simian immunodeficiency virus SIVmac |
| Q39539630 | Impairment of human immunodeficiency virus type 1 (HIV-1) entry into Jurkat T cells by constitutive expression of the HIV-1 vpr protein: role of CD4 down-modulation |
| Q36622894 | In vivo leukocyte tropism of bovine leukemia virus in sheep and cattle. |
| Q36655127 | Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. |
| Q40308974 | Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo |
| Q36287468 | Mapping the determinants of human immunodeficiency virus 2 for infectivity, replication efficiency, and cytopathicity |
| Q39820667 | Molecular biology and pathogenesis of animal lentivirus infections. |
| Q36636712 | Molecular biology of the human immunodeficiency virus accessory proteins |
| Q34379227 | Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation |
| Q35850945 | Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation. |
| Q44645285 | Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells |
| Q33334766 | Pathogenesis of HIV-1 infection within bone marrow cells |
| Q33587139 | Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage |
| Q35856279 | Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice |
| Q36699125 | Role of the fusogenic peptide sequence in syncytium induction and infectivity of human immunodeficiency virus type 2. |
| Q37766007 | Roles of Vpr and Vpx in modulating the virus-host cell relationship |
| Q35860976 | Sequences regulating tropism of human immunodeficiency virus type 1 for brain capillary endothelial cells map to a unique region on the viral genome. |
| Q35882940 | Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1 |
| Q36371387 | Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra. |
| Q36632673 | Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus |
| Q45884182 | Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors |
| Q40358843 | Synthetic Vpr protein activates activator protein-1, c-Jun N-terminal kinase, and NF-kappaB and stimulates HIV-1 transcription in promonocytic cells and primary macrophages |
| Q45768560 | Targeting of chrolamphenicol acetyltransferase to human immunodeficiency virus particles via Vpr and Vpx. |
| Q39079514 | The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention |
| Q36400220 | The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS |
| Q28368083 | The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product |
| Q24685965 | The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle |
| Q35838540 | The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles |
| Q40467649 | The vpr Regulatory Gene of HIV |
| Q36797922 | The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage |
| Q36685908 | Transdominant inhibition of wild-type human immunodeficiency virus type 2 replication by an envelope deletion mutant. |
| Q34173884 | Using death to one's advantage: HIV modulation of apoptosis |
| Q35834804 | V3-independent determinants of macrophage tropism in a primary human immunodeficiency virus type 1 isolate. |
| Q40467618 | Viral Protein X |
| Q33783972 | Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells |
| Q35859146 | Vpr-induced cell cycle arrest is conserved among primate lentiviruses. |
| Q42624207 | Yeast for virus research |
| Q35844498 | vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys |
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