Difluoromethylornithine: the proof is in the polyamines

scientific article

Difluoromethylornithine: the proof is in the polyamines is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1940-6207.CAPR-12-0429
P932PMC publication ID4085686
P698PubMed publication ID23221207

P2093author name stringDavid S Alberts
Joanne M Jeter
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Randomized prospective phase III trial of difluoromethylornithine vs placebo in preventing recurrence of completely resected low risk superficial bladder cancerQ36524475
The effect of difluoromethylornithine on decreasing prostate size and polyamines in men: results of a year-long phase IIb randomized placebo-controlled chemoprevention trialQ36836192
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Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapyQ39599826
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Effect of alpha-difluoromethylornithine on rectal mucosal levels of polyamines in a randomized, double-blinded trial for colon cancer preventionQ44788424
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotionQ44838882
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Evaluation of difluoromethylornithine for the chemoprevention of Barrett's esophagus and mucosal dysplasia.Q51548469
Phase III randomized study of postradiotherapy chemotherapy with alpha-difluoromethylornithine-procarbazine, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosurea, vincristine (DFMO-PCV) versus PCV for glioblastoma multiforme.Q54032299
Chemopreventive efficacy of topical difluoromethylornithine and/or triamcinolone in the treatment of actinic keratoses analyzed by karyometry.Q55518257
Randomized phase I chemoprevention dose-seeking study of alpha-difluoromethylornithineQ70672625
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Chemoprevention of human actinic keratoses by topical 2-(difluoromethyl)-dl-ornithineQ73355841
P433issue12
P304page(s)1341-1344
P577publication date2012-12-01
P1433published inCancer Prevention ResearchQ2665103
P1476titleDifluoromethylornithine: the proof is in the polyamines
P478volume5

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cites work (P2860)
Q35388587A simple and sensitive assay for eflornithine quantification in rat brain using pre-column derivatization and UPLC-MS/MS detection
Q48506495Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases
Q39140722Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance
Q38765477Difluoromethylornithine in cancer: new advances
Q36168155Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth
Q50100821Polyamines and Cancer
Q42085336Say what? The activity of the polyamine biosynthesis inhibitor difluoromethylornithine in chemoprevention is a result of reduced thymidine pools?

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