review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1005296826 |
P356 | DOI | 10.1038/APS.2011.70 |
P932 | PMC publication ID | 4085723 |
P698 | PubMed publication ID | 21623390 |
P5875 | ResearchGate publication ID | 51175535 |
P2093 | author name string | Min Li | |
Zhao-bing Gao | |||
Joseph Babcock | |||
Lian-qing Liu | |||
Ping-zheng Zhou | |||
P2860 | cites work | Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome | Q24299159 |
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel | Q24316252 | ||
The inward rectification mechanism of the HERG cardiac potassium channel | Q24320034 | ||
A family of potassium channel genes related to eag in Drosophila and mammals | Q24563554 | ||
The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics | Q27642109 | ||
The genetic basis of long QT and short QT syndromes: a mutation update | Q28262724 | ||
Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease | Q32061803 | ||
Drug-induced prolongation of the QT interval | Q33151147 | ||
The amiodarone derivative KB130015 activates hERG1 potassium channels via a novel mechanism | Q33716230 | ||
Systems pharmacology of arrhythmias | Q34111154 | ||
Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel | Q34368794 | ||
Is restoration of intracellular trafficking clinically feasible in the long QT syndrome?: The example of HERG mutations. | Q35115334 | ||
Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. | Q35963083 | ||
Voltage sensor movement in the hERG K+ channel. | Q36210620 | ||
The congenital long QT syndromes from genotype to phenotype: clinical implications | Q36335249 | ||
Fast and slow voltage sensor movements in HERG potassium channels | Q36412334 | ||
Targeted therapy for short QT syndrome | Q36481056 | ||
A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator | Q36839526 | ||
The hERG channel and risk of drug-acquired cardiac arrhythmia: an overview | Q37264949 | ||
Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction | Q37332774 | ||
PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance | Q37446552 | ||
Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic aci | Q37464272 | ||
Voltage-gated potassium channels as therapeutic targets | Q37464784 | ||
Delayed rectifier K(+) currents and cardiac repolarization. | Q37580457 | ||
Revealing the structural basis of action of hERG potassium channel activators and blockers | Q37774138 | ||
Electrophysiologic characterization of a novel hERG channel activator | Q39854832 | ||
Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea]. | Q40258104 | ||
High affinity HERG K(+) channel blockade by the antiarrhythmic agent dronedarone: resistance to mutations of the S6 residues Y652 and F656. | Q40492856 | ||
Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. | Q40923240 | ||
Modulation of K+ current by frequency and external [K+]: a tale of two inactivation mechanisms. | Q41290065 | ||
Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity | Q42660591 | ||
Pharmacological removal of human ether-à-go-go-related gene potassium channel inactivation by 3-nitro-N-(4-phenoxyphenyl) benzamide (ICA-105574). | Q43266815 | ||
Dynamic conformational changes of extracellular S5-P linkers in the hERG channel | Q44913448 | ||
Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed | Q46705938 | ||
Mechanism of action of a novel human ether-a-go-go-related gene channel activator | Q46801187 | ||
2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels | Q46879302 | ||
Mallotoxin is a novel human ether-a-go-go-related gene (hERG) potassium channel activator. | Q51804614 | ||
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome | Q73396897 | ||
[HERG K+ channel, the target of anti-arrhythmias drugs] | Q81327520 | ||
P433 | issue | 6 | |
P304 | page(s) | 781-788 | |
P577 | publication date | 2011-05-30 | |
P1433 | published in | Acta Pharmacologica Sinica | Q15749885 |
P1476 | title | Activation of human ether-a-go-go related gene (hERG) potassium channels by small molecules | |
P478 | volume | 32 |
Q42554247 | Channelopathies and drug discovery in the postgenomic era. |
Q37173140 | Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. |
Q34162662 | Exploration of 3-Aminoazetidines as Triple Reuptake Inhibitors by Bioisosteric Modification of 3-α-Oxyazetidine |
Q58695621 | Identification of small-molecule ion channel modulators in C. elegans channelopathy models |
Q35222104 | Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel |
Q26798018 | Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls |
Q38909233 | Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K(+) channel |
Q37172414 | The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands |
Q93074045 | The molecular determinants of R-roscovitine block of hERG channels |
Q27008208 | Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspects |
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