| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.YJMCC.2009.08.005 |
| P698 | PubMed publication ID | 19683534 |
| P50 | author | Flavien Charpentier | Q30225342 |
| Isabelle Baró | Q30225485 | ||
| Gildas Loussouarn | Q30225557 | ||
| P2093 | author name string | Jean Mérot | |
| P2860 | cites work | MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia | Q22009462 |
| KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel | Q24290569 | ||
| AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex | Q24291117 | ||
| Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel | Q24292184 | ||
| 14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity | Q24294353 | ||
| The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family | Q24296263 | ||
| Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome | Q24299159 | ||
| Mutation of an A-kinase-anchoring protein causes long-QT syndrome | Q24304235 | ||
| Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel | Q24307360 | ||
| Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias | Q24311437 | ||
| Suppression of slow delayed rectifier current by a truncated isoform of KvLQT1 cloned from normal human heart | Q24313455 | ||
| Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias | Q24314905 | ||
| A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel | Q24316252 | ||
| Pentamidine-induced long QT syndrome and block of hERG trafficking | Q45038740 | ||
| Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes | Q45166619 | ||
| Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome | Q45299790 | ||
| Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel | Q46174518 | ||
| Voltage sensor of Kv1.2: structural basis of electromechanical coupling | Q46588794 | ||
| The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C. | Q46596511 | ||
| Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle. | Q46675989 | ||
| Nontranscriptional regulation of cardiac repolarization currents by testosterone | Q46699230 | ||
| Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking | Q46714639 | ||
| Mutation in the KCNQ1 gene leading to the short QT-interval syndrome | Q47438291 | ||
| Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels | Q47599689 | ||
| Differential expression of KvLQT1 isoforms across the human ventricular wall | Q47853552 | ||
| Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels | Q48745779 | ||
| KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval | Q48772933 | ||
| Novel gain-of-function mechanism in K(+) channel-related long-QT syndrome: altered gating and selectivity in the HERG1 N629D mutant | Q48896292 | ||
| KCNQ1 assembly and function is blocked by long-QT syndrome mutations that disrupt interaction with calmodulin. | Q50651415 | ||
| De novo KCNQ1 mutation responsible for atrial fibrillation and short QT syndrome in utero. | Q50658517 | ||
| KCNE4 domains required for inhibition of KCNQ1. | Q51784145 | ||
| Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. | Q51809148 | ||
| Atrial fibrillation-associated minK38G/S polymorphism modulates delayed rectifier current and membrane localization. | Q51815243 | ||
| Distinct voltage-dependent regulation of a heart-delayed IK by protein kinases A and C. | Q53854275 | ||
| Charybdotoxin Binding in the IKs Pore Demonstrates Two MinK Subunits in Each Channel Complex | Q58482877 | ||
| A Dominant Negative Isoform of the Long QT Syndrome 1 Gene Product | Q61773877 | ||
| Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action | Q68177119 | ||
| Regulation of a heart potassium channel by protein kinase A and C | Q69839766 | ||
| Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide | Q70523868 | ||
| The role of the delayed rectifier component IKs in dog ventricular muscle and Purkinje fibre repolarization | Q73449781 | ||
| Characterization and functional consequences of delayed rectifier current transient in ventricular repolarization | Q73532264 | ||
| Cyclic AMP regulates the HERG K(+) channel by dual pathways | Q73849628 | ||
| MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel | Q77677778 | ||
| A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome | Q24316980 | ||
| HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family | Q24317712 | ||
| Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel | Q24318271 | ||
| A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome | Q24318498 | ||
| The inward rectification mechanism of the HERG cardiac potassium channel | Q24320034 | ||
| Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation | Q24320049 | ||
| Mutations in the hminK gene cause long QT syndrome and suppress IKs function | Q24323571 | ||
| KCNQ1 gain-of-function mutation in familial atrial fibrillation | Q24338486 | ||
| Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation | Q24534117 | ||
| A comparison of currents carried by HERG, with and without coexpression of MiRP1, and the native rapid delayed rectifier current. Is MiRP1 the missing link? | Q24642143 | ||
| Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2 | Q24647091 | ||
| Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment | Q27649044 | ||
| A common polymorphism associated with antibiotic-induced cardiac arrhythmia | Q28138550 | ||
| Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2 | Q28145423 | ||
| The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels | Q28198311 | ||
| KCNE1 mutations cause jervell and Lange-Nielsen syndrome | Q28253362 | ||
| The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres | Q28254415 | ||
| Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres | Q28255648 | ||
| Cloning of a membrane protein that induces a slow voltage-gated potassium current | Q28292630 | ||
| K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current | Q28295470 | ||
| Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels | Q28300861 | ||
| A structural basis for drug-induced long QT syndrome | Q28344808 | ||
| Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential | Q28345142 | ||
| Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature | Q28379324 | ||
| KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels | Q28580641 | ||
| Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts | Q28589961 | ||
| Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator | Q39911527 | ||
| Endoplasmic reticulum retention and rescue by heteromeric assembly regulate human ERG 1a/1b surface channel composition | Q40042529 | ||
| Identification of IKr and its trafficking disruption induced by probucol in cultured neonatal rat cardiomyocytes | Q40155756 | ||
| A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly | Q40386926 | ||
| Modulation of I(Kr) inactivation by mutation N588K in KCNH2: a link to arrhythmogenesis in short QT syndrome | Q40394221 | ||
| Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG. | Q40643919 | ||
| Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block | Q40724286 | ||
| Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential | Q40997568 | ||
| A derivatized scorpion toxin reveals the functional output of heteromeric KCNQ1-KCNE K+ channel complexes | Q41984559 | ||
| The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4D3 | Q42077037 | ||
| Phosphorylation of the IKs channel complex inhibits drug block: novel mechanism underlying variable antiarrhythmic drug actions | Q42443994 | ||
| Functional characterization of a minimal K+ channel expressed from a synthetic gene | Q42627332 | ||
| Association of the human minK gene 38G allele with atrial fibrillation: evidence of possible genetic control on the pathogenesis of atrial fibrillation | Q43514140 | ||
| Identification of specific pore residues mediating KCNQ1 inactivation. A novel mechanism for long QT syndrome | Q43559407 | ||
| Density and kinetics of I(Kr) and I(Ks) in guinea pig and rabbit ventricular myocytes explain different efficacy of I(Ks) blockade at high heart rate in guinea pig and rabbit: implications for arrhythmogenesis in humans | Q43714041 | ||
| HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate | Q43819707 | ||
| PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents | Q44386912 | ||
| Structure of the HERG K+ channel S5P extracellular linker: role of an amphipathic alpha-helix in C-type inactivation | Q44539325 | ||
| KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents | Q44636891 | ||
| Electrical remodeling in a canine model of ischemic cardiomyopathy | Q44922674 | ||
| KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of I(Ks) current amplitude in the heart | Q44925365 | ||
| Mechanisms of arsenic-induced prolongation of cardiac repolarization | Q44949018 | ||
| I Kr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines | Q30973880 | ||
| Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether-à-go-go-Related Gene. | Q31110568 | ||
| The Long QT Syndrome | Q33155336 | ||
| Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin | Q33911083 | ||
| The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology | Q33989507 | ||
| HERG channel (dys)function revealed by dynamic action potential clamp technique | Q34188575 | ||
| Sudden death associated with short-QT syndrome linked to mutations in HERG. | Q34283788 | ||
| Predicting drug-hERG channel interactions that cause acquired long QT syndrome. | Q34400282 | ||
| In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart | Q34436223 | ||
| Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: role of repolarization reserve | Q35044625 | ||
| Structural determinants and biophysical properties of HERG and KCNQ1 channel gating | Q35080252 | ||
| Is restoration of intracellular trafficking clinically feasible in the long QT syndrome?: The example of HERG mutations. | Q35115334 | ||
| Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels. | Q36266824 | ||
| Secondary structure of a KCNE cytoplasmic domain | Q36295930 | ||
| Fast inactivation causes rectification of the IKr channel | Q36411776 | ||
| Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents | Q36434545 | ||
| Counting membrane-embedded KCNE beta-subunits in functioning K+ channel complexes | Q36446328 | ||
| HERG trafficking and pharmacological rescue of LQTS-2 mutant channels. | Q36446449 | ||
| KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains | Q36667897 | ||
| A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels. | Q36843204 | ||
| Contributions of HERG K+ current to repolarization of the human ventricular action potential | Q36962509 | ||
| hERG channel trafficking: novel targets in drug-induced long QT syndrome | Q36979583 | ||
| The role of abnormal trafficking of KCNE1 in long QT syndrome 5. | Q36979596 | ||
| Regulation of ion transport proteins by membrane phosphoinositides | Q36986504 | ||
| Kv7.1 (KCNQ1) properties and channelopathies. | Q37049827 | ||
| Small GTPase determinants for the Golgi processing and plasmalemmal expression of human ether-a-go-go related (hERG) K+ channels | Q37075295 | ||
| Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome | Q37385262 | ||
| IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules | Q37432325 | ||
| Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation | Q37597861 | ||
| Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia | Q37713628 | ||
| Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization: evidence for clinically significant IKr-IKs alpha-subunit interaction. | Q39767308 | ||
| Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum | Q39896175 | ||
| LQT1-associated mutations increase KCNQ1 proteasomal degradation independently of Derlin-1. | Q39900692 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 37-44 | |
| P577 | publication date | 2009-08-14 | |
| P1433 | published in | Journal of Molecular and Cellular Cardiology | Q2061932 |
| P1476 | title | Delayed rectifier K(+) currents and cardiac repolarization | |
| P478 | volume | 48 |
| Q41298397 | A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer |
| Q33859184 | Activation of human ether-a-go-go related gene (hERG) potassium channels by small molecules |
| Q34814208 | Adrenergic regulation of the rapid component of delayed rectifier K+ currents in guinea pig cardiomyocytes |
| Q43277864 | Adult zebrafish heart as a model for human heart? An electrophysiological study |
| Q36342150 | Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult guinea pig cardiomyocytes |
| Q54957724 | Aldosterone downregulates delayed rectifier potassium currents through an angiotensin type 1 receptor-dependent mechanism. |
| Q85204040 | Alpha-adrenoceptor antagonism by Crassostrea gigas oyster extract inhibits noradrenaline-induced vascular contraction in Wistar rats |
| Q39433065 | An altered expression of genes involved in the regulation of ion channels in atrial myocytes is correlated with the risk of atrial fibrillation in patients with heart failure |
| Q86436522 | BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs) |
| Q39453137 | Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry |
| Q50067400 | Building Atomic Models of the Ion Channels Based on Low Resolution Electron Microscopy Maps and Homology Modeling. |
| Q38022357 | Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current |
| Q37532412 | Distribution and function of sodium channel subtypes in human atrial myocardium |
| Q28395409 | Doxapram hydrochloride aggravates adrenaline-induced arrhythmias accompanied by bidirectional ventricular tachycardia |
| Q36507791 | Dynamics of Phosphoinositide-Dependent Signaling in Sympathetic Neurons. |
| Q33738469 | Effect of Fe(3)O(4)-magnetic nanoparticles on acute exercise enhanced KCNQ(1) expression in mouse cardiac muscle |
| Q39089553 | Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells |
| Q64100197 | Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome |
| Q34158573 | Functional cross-talk between the α1- and β1-adrenergic receptors modulates the rapidly activating delayed rectifier potassium current in guinea pig ventricular myocytes |
| Q38748517 | HIV-Tat induces a decrease in IKr and IKsvia reduction in phosphatidylinositol-(4,5)-bisphosphate availability |
| Q37171934 | Inhibitory effects of glycyrrhetinic Acid on the delayed rectifier potassium current in Guinea pig ventricular myocytes and HERG channel |
| Q34974496 | LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms |
| Q49706119 | Long Noncoding RNA Kcna2 Antisense RNA Contributes to Ventricular Arrhythmias via Silencing Kcna2 in Rats With Congestive Heart Failure |
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| Q85174031 | Pharmacology of Cardiac Potassium Channels |
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| Q37994074 | Stoichiometry of the slow I(ks) potassium channel in human embryonic stem cell-derived myocytes |
| Q37412583 | Structural basis for K(V)7.1-KCNE(x) interactions in the I(Ks) channel complex |
| Q50067406 | Studying Kv Channels Function using Computational Methods |
| Q50088120 | Therapeutic effects of a taurine-magnesium coordination compound on experimental models of type 2 short QT syndrome |
| Q38972172 | Transmural gradients in ion channel and auxiliary subunit expression |
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| Q30499333 | Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel |
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