KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval

scientific article

KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.HRTHM.2007.07.022
P698PubMed publication ID17997361
P5875ResearchGate publication ID5850277

P50authorJesper Hastrup SvendsenQ40232570
Nicole SchmittQ41045624
Alicia LundbyQ42736656
Søren-Peter OlesenQ12338480
P2093author name stringLasse Steen Ravn
P2860cites workA constitutively open potassium channel formed by KCNQ1 and KCNE3Q22011154
Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs-encoding genes and potential implications in regional heterogeneity of their expressionsQ34620520
P433issue12
P921main subjectAtrial FibrillationQ815819
P304page(s)1532-1541
P577publication date2007-08-01
P1433published inHeart RhythmQ2058605
P1476titleKCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval
P478volume4

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cites work (P2860)
Q33162279A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation
Q47671957A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation
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Q33983329Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Q37590158Atrial fibrillation: mechanisms, therapeutics, and future directions
Q34488266Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels
Q38854252Cardiac Delayed Rectifier Potassium Channels in Health and Disease
Q38201409Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia
Q42909841Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.
Q30411829Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1.
Q36011306Characterization of a Chinese KCNQ1 mutation (R259H) that shortens repolarization and causes short QT syndrome 2.
Q37580457Delayed rectifier K(+) currents and cardiac repolarization.
Q26852051Emerging directions in the genetics of atrial fibrillation
Q35218318Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state
Q57260272Familial clustering of atrial fibrillation and comparative longitudinal outcomes of familial and non-familial atrial fibrillation
Q28239461Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation
Q37486999Gating-related molecular motions in the extracellular domain of the IKs channel: implications for IKs channelopathy
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Q47159378Germline versus somatic mutations in genetic atrial fibrillation
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Q33922814Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1
Q30002317In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of  -Adrenergic Receptor Signaling
Q64079832Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D
Q36667897KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains
Q48745779Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels
Q34572613Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation
Q21261490Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation
Q24306464O-glycosylation of the cardiac I(Ks) complex
Q34501117Personalized medicine and atrial fibrillation: will it ever happen?
Q85174031Pharmacology of Cardiac Potassium Channels
Q55114202Polymorphisms but not mutations of the KCNQ1 gene are associated with lone atrial fibrillation in the Chinese Han population.
Q47895566Pro-arrhythmogenic effects of the S140G KCNQ1 mutation in human atrial fibrillation - insights from modelling.
Q35893721Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits
Q57682847Screening of KCNN3 in patients with early-onset lone atrial fibrillation
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Q33644389Structural interplay of KV7.1 and KCNE1 is essential for normal repolarization and is compromised in short QT syndrome 2 (KV7.1-A287T).
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Q37968125The voltage-gated channel accessory protein KCNE2: multiple ion channel partners, multiple ways to long QT syndrome
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Q35742142Your Father and Grandfather's Atrial Fibrillation: A Review of the Genetics of the Most Common Pathologic Cardiac Dysrhythmia

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