Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential

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Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1469-7793.2001.00721.X
P932PMC publication ID2278748
P698PubMed publication ID11483703
P5875ResearchGate publication ID11858836

P2093author name stringA Besana
A Zaza
G B Gurrola
L D Possani
M Rocchetti
P2860cites workPositional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmiasQ24311437
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channelQ24316252
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndromeQ24316980
Voltage-dependent inactivation of the human K+ channel KvLQT1 is eliminated by association with minimal K+ channel (minK) subunitsQ24653858
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.Q33174548
Genetic and molecular basis of cardiac arrhythmias; impact on clinical management. Study group on molecular basis of arrhythmias of the working group on arrhythmias of the european society of cardiologyQ33542562
The QT interval and torsade de pointesQ33794458
Fast inactivation causes rectification of the IKr channelQ36411776
Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agentsQ36434545
Time-dependent outward current in guinea pig ventricular myocytes. Gating kinetics of the delayed rectifierQ36434641
A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venomQ40957273
Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potentialQ40997568
Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytesQ44311850
Subcellular mechanism for Ca(2+)-dependent enhancement of delayed rectifier K+ current in isolated membrane patches of guinea pig ventricular myocytesQ46532299
Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytesQ48933794
Alteration of HERG current profile during the cardiac ventricular action potential, following a pore mutation.Q52226260
Intracellular Ca2+ and protein kinase C modulate K+ current in guinea pig heart cells.Q53873735
Rapid and slow components of delayed rectifier current in human atrial myocytes.Q54193314
Disulfide bridges of ergtoxin, a member of a new sub-family of peptide blockers of the ether-a-go-go-related K+ channel.Q55034294
Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clampQ67666676
Differential Response of QTU Interval to Exercise, Isoproterenol, and Atrial Pacing in Patients with Congenital Long QT SyndromeQ67706072
Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilideQ70523868
Evidence for two components of delayed rectifier K+ current in human ventricular myocytesQ71089385
Characterization and functional consequences of delayed rectifier current transient in ventricular repolarizationQ73532264
KvLQT1 potassium channel but not IsK is the molecular target for trans-6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethyl- chromaneQ73937536
Dynamic Ca2+-induced inward rectification of K+ current during the ventricular action potentialQ74582123
P433issuePt 3
P407language of work or nameEnglishQ1860
P921main subjectpigQ787
P304page(s)721-32
P577publication date2001-08-01
P1433published inJournal of PhysiologyQ7743612
P1476titleRate dependency of delayed rectifier currents during the guinea-pig ventricular action potential
P478volume534

Reverse relations

cites work (P2860)
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Q35064579A novel approach to identifying antiarrhythmic drug targets
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Q43263275Beta-adrenoceptor activation plays a role in the reverse rate-dependency of effective refractory period lengthening by dofetilide in the guinea-pig atrium, in vitro
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Q51004136Combined action potential- and dynamic-clamp for accurate computational modelling of the cardiac IKr current.
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Q28541597Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependence
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Q46158402Rate dependency of beta-adrenergic modulation of repolarizing currents in the guinea-pig ventricle.
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Q24634668Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias
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