scholarly article | Q13442814 |
P2093 | author name string | Yonathan F Melman | |
Thomas V McDonald | |||
Anna Kagan | |||
Andrew Krumerman | |||
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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches | Q22337395 | ||
AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex | Q24291117 | ||
The 14-3-3 protein binds its target proteins with a common site located towards the C-terminus | Q48636298 | ||
Structure and sites of phosphorylation of 14-3-3 protein: role in coordinating signal transduction pathways. | Q48667801 | ||
Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A. | Q48909397 | ||
Modulation of the Ca(2+)-activated Cl(-) channel by 14-3-3epsilon. | Q50719734 | ||
14-3-3 proteins double the number of outward-rectifying K+ channels available for activation in tomato cells | Q52171422 | ||
Identification of soluble protein phosphatases that dephosphorylate voltage-sensitive sodium channels in rat brain | Q72132255 | ||
Protein phosphorylation and cardiac function: cholinergic-adrenergic interaction | Q72722195 | ||
Glucocorticoid receptor interaction with 14-3-3 and Raf-1, a proposed mechanism for cross-talk of two signal transduction pathways | Q73004180 | ||
A plethora of mechanisms in the HERG-related long QT syndrome. Genetics meets electrophysiology | Q73482820 | ||
The dominant negative LQT2 mutation A561V reduces wild-type HERG expression | Q73643302 | ||
Analysis of the cyclic nucleotide binding domain of the HERG potassium channel and interactions with KCNE2 | Q73693862 | ||
Cyclic AMP regulates the HERG K(+) channel by dual pathways | Q73849628 | ||
Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II | Q77932855 | ||
Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex. a role for scaffolding in enzyme regulation | Q24291204 | ||
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel | Q24292184 | ||
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel | Q24316252 | ||
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine | Q24322674 | ||
Phosphorylation-dependent regulation of ryanodine receptors: a novel role for leucine/isoleucine zippers | Q24678432 | ||
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding | Q27619633 | ||
Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways | Q27729753 | ||
Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97 | Q28200159 | ||
14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange | Q28208614 | ||
A minK-HERG complex regulates the cardiac potassium current I(Kr) | Q28244324 | ||
14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain | Q28246442 | ||
The complexity of Raf-1 regulation | Q28305850 | ||
A structural basis for drug-induced long QT syndrome | Q28344808 | ||
A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2 | Q28572706 | ||
KChAP as a chaperone for specific K(+) channels | Q28575980 | ||
The AKT3 potassium channel protein interacts with the AtPP2CA protein phosphatase 2C | Q28593847 | ||
The structural basis for 14-3-3:phosphopeptide binding specificity | Q29547190 | ||
14-3-3 proteins: structure, function, and regulation | Q29619100 | ||
Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display | Q30776583 | ||
Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin- 3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation | Q32061766 | ||
The molecular genetics of the long QT syndrome: genes causing fainting and sudden death | Q33175543 | ||
The long QT syndrome: ion channel diseases of the heart | Q33175550 | ||
Modulation of ion channels: a "current" view of AKAPs | Q33703246 | ||
The zeta isoform of 14-3-3 proteins interacts with the third intracellular loop of different alpha2-adrenergic receptor subtypes | Q33860370 | ||
The long QT syndromes: genetic basis and clinical implications | Q33970623 | ||
Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2. | Q34150435 | ||
Regulation of the cardiac repolarizing HERG potassium channel by protein kinase A. | Q34204693 | ||
I(Kr): the hERG channel | Q34245075 | ||
14-3-3 proteins; bringing new definitions to scaffolding | Q34405540 | ||
Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association. | Q39426606 | ||
14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity | Q39575866 | ||
A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP. | Q40557820 | ||
Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons | Q40788634 | ||
Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. | Q40923240 | ||
HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects | Q41018746 | ||
A dynamically regulated 14-3-3, Slob, and Slowpoke potassium channel complex in Drosophila presynaptic nerve terminals | Q47070572 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Potassium voltage-gated channel subfamily H member 2 | Q905000 |
regulation of potassium ion transmembrane transport | Q14905768 | ||
negative regulation of peptidyl-serine dephosphorylation | Q21100618 | ||
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon | Q21109282 | ||
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta | Q21109299 | ||
positive regulation of peptidyl-serine dephosphorylation | Q21111840 | ||
regulation of peptidyl-serine dephosphorylation | Q22245333 | ||
P304 | page(s) | 1889-1898 | |
P577 | publication date | 2002-04-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | 14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity | |
P478 | volume | 21 |
Q35879488 | 14-3-3 Proteins--a focus on cancer and human disease |
Q44406301 | 14-3-3 dimers probe the assembly status of multimeric membrane proteins |
Q24338103 | 14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5 |
Q24336445 | 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking |
Q36593662 | 14-3-3 proteins in membrane protein transport |
Q33188355 | 14-3-3 proteins in the nervous system |
Q48763628 | 14-3-3 proteins regulate the potassium channel KAT1 by dual modes. |
Q28576095 | 14-3-3θ is a binding partner of rat Eag1 potassium channels |
Q35048822 | 14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels |
Q51771328 | A KCR1 variant implicated in susceptibility to the long QT syndrome |
Q38564770 | A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1 |
Q36848987 | A-kinase anchoring protein targeting of protein kinase A and regulation of HERG channels |
Q45057657 | Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors |
Q39084989 | Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems. |
Q51804702 | C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon. |
Q33150865 | Clinical and electrophysiological characterization of a novel mutation R863X in HERG C-terminus associated with long QT syndrome |
Q37999317 | Cytoplasmic domains and voltage-dependent potassium channel gating. |
Q37580457 | Delayed rectifier K(+) currents and cardiac repolarization. |
Q33970029 | Depletion of 14-3-3γ reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death. |
Q33581858 | Dimerization is essential for 14-3-3zeta stability and function in vivo |
Q35813584 | Downregulation of urea transporter UT-A1 activity by 14-3-3 protein |
Q47141643 | Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes |
Q44216612 | ERG K+ channels modulate the electrical and contractile activities of gallbladder smooth muscle |
Q40413448 | Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature |
Q28215227 | Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals |
Q81197748 | Genetic isolation of transport signals directing cell surface expression |
Q39911527 | Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator |
Q40086589 | HERG1 currents in native K562 leukemic cells |
Q35850591 | Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs |
Q30973880 | I Kr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines |
Q90354864 | Identification of Aberrantly Expressed lncRNAs Involved in Orthodontic Force Using a Subpathway Strategy |
Q57673140 | Inherited Cardiomyopathies and the Role of Mutations in Non-coding Regions of the Genome |
Q39444757 | Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells |
Q24641890 | Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3 |
Q48729332 | Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins |
Q28087459 | Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death |
Q37901394 | Ion channels as targets for cancer therapy |
Q42840259 | Ion channels in volume regulation of clonal kidney cells |
Q41849048 | K(+) channels and cell cycle progression in tumor cells |
Q33317280 | K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If. |
Q45719472 | Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone |
Q47098189 | Kv4.3 Modulates the Distribution of hERG. |
Q44636891 | KvLQT1 modulates the distribution and biophysical properties of HERG. A novel alpha-subunit interaction between delayed rectifier currents |
Q36100237 | Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis |
Q37888994 | Membrane proteins as 14-3-3 clients in functional regulation and intracellular transport |
Q40158533 | Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits. |
Q35540339 | Molecular Mechanisms and Regulation of K+ Transport in Higher Plants |
Q36514294 | Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias |
Q40722220 | Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease |
Q38130386 | Molecular basis of potassium channels in pancreatic duct epithelial cells |
Q44279213 | Monomeric 14-3-3 protein is sufficient to modulate the activity of the Drosophila slowpoke calcium-dependent potassium channel |
Q34993298 | PI3K/Akt signalling-mediated protein surface expression sensed by 14-3-3 interacting motif |
Q37200218 | PKA phosphorylation of HERG protein regulates the rate of channel synthesis. |
Q41904877 | PPARδ activity in cardiovascular diseases: A potential pharmacological target |
Q48735323 | Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor. |
Q36876075 | Phosphatidylinositol 4,5-bisphosphate interactions with the HERG K(+) channel. |
Q34051621 | Post-transcriptional control of human ether-a-go-go-related gene potassium channel protein by alpha-adrenergic receptor stimulation. |
Q35065301 | Protein kinase A activity at the endoplasmic reticulum surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG). |
Q42809404 | Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon |
Q37193903 | Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation |
Q35636217 | Regulation of K+ channel activities in plants: from physiological to molecular aspects |
Q37259560 | Regulation of cardiac excitation and contraction by p21 activated kinase-1 |
Q37767379 | Role of ERG1 isoforms in modulation of ERG1 channel trafficking and function |
Q44218010 | The 14-3-3 protein as a novel regulator of ion channel localisation |
Q45275689 | The 14-3-3 protein translates the NA+,K+-ATPase {alpha}1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis |
Q36730662 | The nervous heart |
Q44368272 | The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3 protein gamma and epsilon isoforms |
Q24324091 | The regulation of the cardiac potassium channel (HERG) by caveolin-1 |
Q35661122 | The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel |
Q35217946 | The viral potassium channel Kcv: structural and functional features. |
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