The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel

scientific article published on 15 November 2011

The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JIM.2011.10.014
P932PMC publication ID3253882
P698PubMed publication ID22107967
P5875ResearchGate publication ID51821605

P2093author name stringMatthew D Scharff
Thomas V McDonald
Jakub Sroubek
Yamini Krishnan
Susan Buhl
Jordan Chinai
P2860cites workDifferential association between HERG and KCNE1 or KCNE2Q21562313
14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activityQ24294353
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channelQ24316252
Escherichia coli maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fusedQ28142404
The genetic basis of long QT and short QT syndromes: a mutation updateQ28262724
Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effectsQ28374793
Long QT Syndrome.Q33148863
The long QT syndrome family of cardiac ion channelopathies: a HuGE reviewQ33153638
Electrophysiological remodeling in hypertrophy and heart failureQ33758963
Arrhythmias in heart failure: current concepts of mechanisms and therapyQ33850477
Ventricular tachycardia with 2 variable opposing fociQ34224683
Generation of a fusion partner to sample the repertoire of splenic B cells destined for apoptosisQ35486835
Biology of cardiac arrhythmias: ion channel protein traffickingQ35802024
PKA phosphorylation of HERG protein regulates the rate of channel synthesis.Q37200218
Drug-induced hERG block and long QT syndromeQ37734559
Expression and purification of the first nucleotide-binding domain and linker region of human multidrug resistance gene product: comparison of fusions to glutathione S-transferase, thioredoxin and maltose-binding proteinQ38328649
Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cellsQ39971749
Production of monoclonal antibodies: strategy and tacticsQ40300743
Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanismQ40326013
Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.Q40643919
Metabolic inhibition of ICa,L and IK differs in feline left ventricular hypertrophy.Q51639096
Clinical evaluation of QT/QTc prolongation and proarrhythmic potential for nonantiarrhythmic drugs: the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use E14 guideline.Q53256610
International Conference on Harmonisation; guidance on E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs; availability. Notice.Q53265213
Somatic cell genetic analysis of myelomas and hybridomasQ68543636
VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcomeQ80125721
P433issue1-2
P304page(s)215-222
P577publication date2011-11-15
P1433published inJournal of Immunological MethodsQ15755939
P1476titleThe use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel
P478volume375

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Q34539842A "Trojan horse" bispecific-antibody strategy for broad protection against ebolavirusescites workP2860

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