VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome

scientific article published on 09 April 2007

VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2006-02-003772
P698PubMed publication ID17420287

P2093author name stringAnnarosa Arcangeli
Andrea Becchetti
Serena Pillozzi
Maria Felice Brizzi
Vieri Boddi
Benedetta Bartolozzi
Roberto Caporale
Luigi Pegoraro
Venere Basile
Pietro Antonio Bernabei
P433issue4
P921main subjectcell migrationQ189092
acute myeloid leukemiaQ264118
P304page(s)1238-1250
P577publication date2007-04-09
P1433published inBloodQ885070
P1476titleVEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome
P478volume110

Reverse relations

cites work (P2860)
Q42395802A comment on ion channels as pharmacological targets in oncology
Q41761513A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®).
Q36738745A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for "smart" small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cells
Q48221690A role for potassium permeability in the recognition, clearance, and anti-inflammatory effects of apoptotic cells
Q40019515Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channels
Q61813975Adhesion Deregulation in Acute Myeloid Leukaemia
Q36200930Aquaporin 2 promotes cell migration and epithelial morphogenesis
Q37457834BKCa promotes growth and metastasis of prostate cancer through facilitating the coupling between αvβ3 integrin and FAK.
Q33995612Ceramide modulates HERG potassium channel gating by translocation into lipid rafts
Q37482529Characterization of hERG1 channel role in mouse colorectal carcinogenesis.
Q42660203Differential expression of hERG1A and hERG1B genes in pediatric acute lymphoblastic leukemia identifies different prognostic subgroups.
Q43263512Effect of Gambogic acid on the regulation of hERG channel in K562 cells in vitro
Q35600054Effect of celastrol on growth inhibition of prostate cancer cells through the regulation of hERG channel in vitro
Q34927241Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells.
Q55231478Expression of KATP channels in human cervical cancer: Potential tools for diagnosis and therapy.
Q38184988Functional properties of ion channels and transporters in tumour vascularization.
Q34221680HERG1 functions as an oncogene in pancreatic cancer and is downregulated by miR-96.
Q36501076HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms
Q81951836ICER expression inhibits leukemia phenotype and controls tumor progression
Q38707271IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines
Q39971749Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells
Q37173281Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells
Q54334505Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia.
Q41959589Immunohistochemical biomarkers in gastric cancer research and management
Q64075361Implication of Voltage-Gated Potassium Channels in Neoplastic Cell Proliferation
Q28534789Integrated analysis of drug-induced gene expression profiles predicts novel hERG inhibitors
Q38184985Interaction of tumour cells with their microenvironment: ion channels and cell adhesion molecules. A focus on pancreatic cancer
Q26849490Ion channels and transporters in tumour cell migration and invasion
Q90335558Ion channels as therapeutic antibody targets
Q42277895Ion channels in hematopoietic and mesenchymal stem cells
Q37702927Ion channels under the sun.
Q37152732Ion channels: functional expression and therapeutic potential in cancer. Colloquium on Ion Channels and Cancer
Q33699387Irresponsiveness of two retinoblastoma cases to conservative therapy correlates with up- regulation of hERG1 channels and of the VEGF-A pathway.
Q27324841K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated Manner
Q39188078Kv3.4 potassium channel-mediated electrosignaling controls cell cycle and survival of irradiated leukemia cells
Q37201859LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer
Q34024653Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels.
Q35862717Multimerin-1 (MMRN1) as Novel Adverse Marker in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group
Q37783442New Insights into the Regulation of Ion Channels by Integrins
Q38974256New Trends in Cancer Therapy: Targeting Ion Channels and Transporters
Q27007789New targets for the antitumor activity of gambogic acid in hematologic malignancies
Q90193598Noncanonical Ion Channel Behaviour in Pain
Q27015660Novel roles for hERG K(+) channels in cell proliferation and apoptosis
Q37321844Over-Expression of the LH Receptor Increases Distant Metastases in an Endometrial Cancer Mouse Model
Q42061814Placing ion channels into a signaling network of T cells: from maturing thymocytes to healthy T lymphocytes or leukemic T lymphoblasts.
Q41616259Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways.
Q53391411Prognostic significance of hERG1 expression in gastric cancer.
Q43228471Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice
Q39372092Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas.
Q38361335Role of ion channels in regulating Ca²⁺ homeostasis during the interplay between immune and cancer cells
Q38110508Roles of ion transport in control of cell motility
Q35688524Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation.
Q35150041Sig1R protein regulates hERG channel expression through a post-translational mechanism in leukemic cells.
Q38896670Sigma 1 Receptor and Ion Channel Dynamics in Cancer
Q90454252Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer
Q37162402State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy
Q36528727Stem-cell ecology and stem cells in motion
Q47827712TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.
Q33937726Targeting potassium channels in cancer
Q64244710The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells
Q46097844The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.
Q64913436The ion channels and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma.
Q33715775The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia
Q46078309The role of hERG1 K+ channels and a functional link between hERG1 K+ channels and SDF-1 in acute leukemic cell migration
Q36124907The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment
Q38171243The roles of K(+) channels in cancer
Q38123807The sigma-1 receptor: a regulator of cancer cell electrical plasticity?
Q35661122The use of Bcl-2 over-expression to stabilize hybridomas specific to the HERG potassium channel
Q37521165Up-regulation of hERG K⁺ channels by B-RAF.
Q61454129Voltage-gated K channels promote BT-474 breast cancer cell migration
Q37464784Voltage-gated potassium channels as therapeutic targets
Q35081094hERG potassium channel blockage by scorpion toxin BmKKx2 enhances erythroid differentiation of human leukemia cells K562
Q35882249hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study
Q35198312hERG1 channels drive tumour malignancy and may serve as prognostic factor in pancreatic ductal adenocarcinoma.
Q39056231hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer

Search more.