5-ALA mediated photodynamic therapy induces autophagic cell death via AMP-activated protein kinase

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5-ALA mediated photodynamic therapy induces autophagic cell death via AMP-activated protein kinase is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1038055919
P356DOI10.1186/1476-4598-9-91
P932PMC publication ID2873441
P698PubMed publication ID20426806
P5875ResearchGate publication ID43350884

P2093author name stringLi-Ting Chien
Chin-Tin Chen
Hong-Tai Ji
Hsiung-Fei Chien
Yu-Hsin Lin
P2860cites workRole of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapyQ40321304
AMPK activation regulates apoptosis, adipogenesis, and lipolysis by eIF2alpha in adipocytesQ40336306
Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cellsQ40344982
AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinaseQ40657762
Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cellsQ40707175
Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapyQ41003785
Characterization of the mucin differentiation in human lung adenocarcinoma cell linesQ41610423
Photodynamic therapy mediates immediate loss of cellular responsiveness to cytokines and growth factors.Q42163148
The role of the peripheral benzodiazepine receptor in the apoptotic response to photodynamic therapy.Q43730942
Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.Q53665783
Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.Q55064927
AMP-activated Protein Kinase and the Regulation of Autophagic ProteolysisQ56777095
Inhibition of glucocorticoid-induced apoptosis with 5-aminoimidazole-4-carboxamide ribonucleoside, a cell-permeable activator of AMP-activated protein kinaseQ74311172
Photodynamic therapyQ74688364
Photodynamic therapy: a mitochondrial inducer of apoptosisQ77315778
Role of AMP-activated protein kinase in mechanism of metformin actionQ22241898
The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytesQ24290792
The AMP-activated protein kinase--fuel gauge of the mammalian cell?Q24315074
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processingQ24597817
Biosynthesis of delta-aminolevulinic acid and the regulation of heme formation by immature erythroid cells in manQ28678681
Autophagy in cell death: an innocent convict?Q29617604
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosisQ29622875
Effect of 5-aminolevulinic acid-mediated photodynamic therapy on MCF-7 and MCF-7/ADR cells.Q31039596
Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4.Q33185113
Reorganization of cytoskeleton induced by 5-aminolevulinic acid-mediated photodynamic therapy and its correlation with mitochondrial dysfunction.Q33214457
Initiation of apoptosis and autophagy by photodynamic therapyQ33239933
Dealing with energy demand: the AMP-activated protein kinaseQ33543966
Photodynamic therapy for cancerQ34194073
Management of cellular energy by the AMP-activated protein kinase systemQ34209246
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.Q34859478
The role of apoptosis in response to photodynamic therapy: what, where, why, and how.Q35092776
Methods for monitoring autophagyQ35869399
Intracellular signaling mechanisms in photodynamic therapyQ35885684
Properties and applications of photodynamic therapy.Q35897172
Autophagy: dual roles in life and death?Q36146947
Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brainQ36475846
Autophagy, mitochondrial quality control, and oncogenesisQ36549509
Molecular effectors of multiple cell death pathways initiated by photodynamic therapyQ36907982
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injuryQ37286204
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L.Q39972651
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activityQ40259774
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell linesQ40278287
P921main subjectaminolevulinic acidQ238474
autophagyQ288322
cell deathQ2383867
P304page(s)91
P577publication date2010-04-28
P1433published inMolecular CancerQ15724585
P1476title5-ALA mediated photodynamic therapy induces autophagic cell death via AMP-activated protein kinase
P478volume9

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cites work (P2860)
Q995662909-phenyl acridine photosensitizes A375 cells to UVA radiation
Q94188972Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
Q57273332Amphiphilic chitosan modified upconversion nanoparticles for in vivo photodynamic therapy induced by near-infrared light
Q36859217Apoptosis and autophagy induced by pyropheophorbide-α methyl ester-mediated photodynamic therapy in human osteosarcoma MG-63 cells
Q38202871Autophagy Contributes to the Death/Survival Balance in Cancer PhotoDynamic Therapy.
Q38349813Autophagy, a major adaptation pathway shaping cancer cell death and anticancer immunity responses following photodynamic therapy
Q34549203Chloride intracellular channel 4 involves in the reduced invasiveness of cancer cells treated by photodynamic therapy.
Q33739471Doxycycline potentiates antitumor effect of 5-aminolevulinic acid-mediated photodynamic therapy in malignant peripheral nerve sheath tumor cells
Q94457800Enhanced anti-tumor efficacy of 5-aminolevulinic acid-gold nanoparticles-mediated photodynamic therapy in cutaneous squamous cell carcinoma cells
Q50448694Ex vivo evaluation of the effect of photodynamic therapy on skin scars and striae distensae.
Q46831195HMME-based PDT restores expression and function of transporter associated with antigen processing 1 (TAP1) and surface presentation of MHC class I antigen in human glioma
Q39251853Light fractionated ALA-PDT enhances therapeutic efficacy in vitro; the influence of PpIX concentration and illumination parameters
Q35386782Magnetic-luminescent YbPO4:Er,Dy microspheres designed for tumor theranostics with synergistic effect of photodynamic therapy and chemotherapy.
Q40979804Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy in vitro
Q34068201Photochemical internalization of tumor-targeted protein toxins.
Q39125005Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy
Q33713297Use of the dietary supplement 5-aminiolevulinic acid (5-ALA) and its relationship with glucose levels and hemoglobin A1C among individuals with prediabetes

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