scholarly article | Q13442814 |
P2093 | author name string | V Ling | |
J M Ruysschaert | |||
A B Shapiro | |||
N Sonveaux | |||
C Vigano | |||
P2860 | cites work | ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells | Q24650215 |
A simplification of the protein assay method of Lowry et al. which is more generally applicable | Q29615220 | ||
Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil | Q33651186 | ||
The catalytic cycle of P-glycoprotein | Q34370183 | ||
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein | Q36589430 | ||
Reconstitution of Drug Transport by Purified P-glycoprotein | Q36687072 | ||
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity | Q36712329 | ||
Cellular uptake, cytotoxicity, and transport kinetics of anthracyclines in human sensitive and multidrug-resistant K562 cells | Q36817416 | ||
P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer. | Q36895019 | ||
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities | Q36895030 | ||
Topological folding and proteolysis profile of P-glycoprotein in membranes of multidrug-resistant cells: implications for the drug-transport mechanism. | Q38355020 | ||
Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence | Q38358911 | ||
The biochemistry of P-glycoprotein-mediated multidrug resistance | Q38364215 | ||
ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance | Q40384605 | ||
Conformational changes of P-glycoprotein by nucleotide binding | Q41067952 | ||
P-glycoprotein--a mediator of multidrug resistance in tumour cells | Q41078108 | ||
MDR1 gene expression in solid tumours | Q41078192 | ||
Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity | Q41293154 | ||
P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site | Q41310191 | ||
Membrane topology of a cysteine-less mutant of human P-glycoprotein | Q41380800 | ||
The P-glycoprotein efflux pump: how does it transport drugs? | Q41678834 | ||
Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites | Q47922050 | ||
Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains. | Q50535941 | ||
Dissection of drug-binding-induced conformational changes in P-glycoprotein. | Q54127126 | ||
Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. | Q54216853 | ||
P433 | issue | 25 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | fluorescence quenching | Q585536 |
P304 | page(s) | 17649-17654 | |
P577 | publication date | 1999-06-01 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Ligand-mediated tertiary structure changes of reconstituted P-glycoprotein. A tryptophan fluorescence quenching analysis | |
P478 | volume | 274 |
Q53705160 | A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein. |
Q41735425 | A conformation change in the carboxyl terminus of Alzheimer's Abeta (1-40) accompanies the transition from dimer to fibril as revealed by fluorescence quenching analysis |
Q54453791 | A novel ligand bound ABC transporter, LolCDE, provides insights into the molecular mechanisms underlying membrane detachment of bacterial lipoproteins. |
Q46307680 | Autofluorescence and Nonspecific Immunofluorescent Labeling in Frozen Bovine Intestinal Tissue Sections: Solutions for Multicolor Immunofluorescence Experiments |
Q46367702 | Benzodiazepine-mediated structural changes in the multidrug transporter P-glycoprotein: an intrinsic fluorescence quenching analysis |
Q45001388 | Concentration dependency of modulatory effect of amlodipine on P-glycoprotein efflux activity of doxorubicin--a comparison with tamoxifen |
Q42284764 | Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein |
Q28366017 | Detailed characterization of cysteine-less P-glycoprotein reveals subtle pharmacological differences in function from wild-type protein |
Q35644350 | Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators |
Q48269107 | Insights Into the Molecular Mechanism of Triptan Transport by P-glycoprotein. |
Q37411852 | Interaction of human serum albumin with novel 3,9-disubstituted perylenes |
Q34158355 | Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione |
Q38341900 | Maltose-binding protein is open in the catalytic transition state for ATP hydrolysis during maltose transport |
Q42804394 | Many P-glycoprotein substrates do not inhibit the transport process across cell membranes |
Q42614676 | Mapping daunorubicin-binding Sites in the ATP-binding cassette transporter MsbA using site-specific quenching by spin labels |
Q42688822 | Molecular dynamics simulations of E. coli MsbA transmembrane domain: formation of a semipore structure |
Q34290848 | Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism |
Q40817588 | Nucleotide-induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells |
Q44982216 | P-glycoprotein retains function when reconstituted into a sphingolipid- and cholesterol-rich environment |
Q26777721 | Providing a molecular mechanism for P-glycoprotein; why would I bother? |
Q36386127 | Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux. |
Q24535845 | Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle |
Q33897307 | Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis. A fourier transform attenuated total reflection infrared spectroscopy and tryptophan fluorescence quenching analysis. |
Q48313444 | Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1). |
Q28585772 | Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy |
Q36786255 | Structure and function of ABC transporters |
Q36579583 | Structure and function of ABC transporters: the ATP switch provides flexible control |
Q37591245 | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity |
Q47965610 | Substitution at the C-3 Position of Catechins Has an Influence on the Binding Affinities against Serum Albumin. |
Q34353789 | The ATP switch model for ABC transporters |
Q42665190 | The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA. |
Q40400095 | The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment. |
Q73526045 | The effect of glutathione on the ATPase activity of MRP1 in its natural membranes |
Q58195302 | The flexibility of P-glycoprotein for its poly-specific drug binding from molecular dynamics simulations |
Q28776849 | The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism |
Q40546719 | The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein. |
Q36354417 | The translocation mechanism of P-glycoprotein. |
Q42691597 | Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding |
Q42451287 | Transition State Analysis of the Coupling of Drug Transport to ATP Hydrolysis by P-glycoprotein |
Q42105486 | Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1. |
Q36525551 | Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins |
Q40253896 | Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase |
Q42182875 | Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2. |
Q36691249 | Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein |
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