Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats

scientific article

Effect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1167/IOVS.10-6262
P932PMC publication ID3176033
P698PubMed publication ID21482645
P5875ResearchGate publication ID51041445

P50authorZhiming SongQ59690562
P2093author name stringJuanjuan Wang
Yun-Zheng Le
Yanyan Bai
Meili Zhu
Daniel W Gil
Edwin Padillo
Jyotirmoy Kusari
Sheila X Zhou
P2860cites workInterleukin 6 induces the expression of vascular endothelial growth factorQ24316308
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluidQ29617640
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesisQ29617644
VEGF is major stimulator in model of choroidal neovascularization.Q30914479
Foveolar choroidal blood flow in age-related macular degeneration.Q32111311
Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy.Q33264002
A novel imaging technique for experimental choroidal neovascularizationQ33264433
Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularizationQ33394749
Oxidative damage and age-related macular degenerationQ33774187
Retinal and choroidal neovascularizationQ33980639
Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes.Q34062411
Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakageQ34082890
Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularizationQ34749337
Role of alpha-2 agonists in neuroprotectionQ35174036
Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularizationQ35745444
Erythropoietin deficiency decreases vascular stability in mice.Q36404124
Vascular endothelial growth factor expression in choroidal neovascularization in ratsQ36864325
Inhibition of retinal neovascularization by siRNA targeting VEGF(165)Q36957634
Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degenerationQ37294413
Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathyQ37607034
Introduction: Understanding the role of angiogenesis and antiangiogenic agents in age-related macular degenerationQ37607656
Effect of memantine on neuroretinal function and retinal vascular changes of streptozotocin-induced diabetic ratsQ42520811
Müller cell-derived VEGF is a significant contributor to retinal neovascularizationQ43273707
Inhibition of vitreoretinal VEGF elevation and blood-retinal barrier breakdown in streptozotocin-induced diabetic rats by brimonidineQ43285278
alpha(2)-Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemiaQ43512831
Neuroprotective effects of alpha(2)-selective adrenergic agonists against ischemia-induced retinal ganglion cell deathQ43693068
Brimonidine's neuroprotective effects against transient ischaemia-induced retinal ganglion cell death.Q43760623
Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.Q44329008
Kinetics of retinal vaso-obliteration and neovascularisation in the oxygen-induced retinopathy (OIR) mouse model.Q45969448
Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicityQ46097757
Descending doses of intravitreal bevacizumab for the regression of diabetic neovascularization.Q46167343
Time-course of experimental choroidal neovascularization in Dutch-Belted rabbit: clinical and histological evaluationQ46675298
Ischemia results 3 months later in altered ERG, degeneration of inner layers, and deafferented tectum: neuroprotection with brimonidineQ46722468
Neuroprotective effect of topically applied brimonidine tartrate 0.2% in endothelin-1-induced optic nerve ischaemia model.Q50923300
The relation between expression of vascular endothelial growth factor and breakdown of the blood-retinal barrier in diabetic rat retinasQ71013356
Subfoveal fibrovascular membranes in age-related macular degeneration express vascular endothelial growth factorQ71402232
Oxygen-induced retinopathy in the mouseQ71608431
Retinopathy of prematurity: recent advances in our understandingQ74649816
From the lab to the clinic: activation of an alpha-2 agonist pathway is neuroprotective in models of retinal and optic nerve injuryQ77407174
The rationale for drug combinations in age-related macular degenerationQ84123394
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectneovascularizationQ1281049
retinopathy of prematurityQ1423087
P304page(s)5424-5431
P577publication date2011-07-20
P1433published inInvestigative Ophthalmology Visual ScienceQ6060707
P1476titleEffect of brimonidine on retinal and choroidal neovascularization in a mouse model of retinopathy of prematurity and laser-treated rats
P478volume52

Reverse relations

cites work (P2860)
Q8412062217-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model
Q34612126A novel in vivo model of focal light emitting diode-induced cone-photoreceptor phototoxicity: neuroprotection afforded by brimonidine, BDNF, PEDF or bFGF.
Q90379236Collagen peptide modified carboxymethyl cellulose as both antioxidant drug and carrier for drug delivery against retinal ischaemia/reperfusion injury
Q38885566Integrative concepts of rosacea pathophysiology, clinical presentation and new therapeutics
Q42576282Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection
Q42151817Overexpression of Heme Oxygenase-1 in Mesenchymal Stem Cells Augments Their Protection on Retinal Cells In Vitro and Attenuates Retinal Ischemia/Reperfusion Injury In Vivo against Oxidative Stress
Q84789929Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR
Q38644369Pomegranate protective effect on experimental ischemia/reperfusion retinal injury in rats (histological and biochemical study).
Q49381318Safety threshold of intravitreal clonidine in rabbit's eyes.
Q35484906Sulforaphane protects rodent retinas against ischemia-reperfusion injury through the activation of the Nrf2/HO-1 antioxidant pathway
Q37980016The emerging role of stem cells in ocular neurodegeneration: hype or hope?
Q92342987Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity
Q92277510Update on the Management of Rosacea from the American Acne & Rosacea Society (AARS)

Search more.