Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis

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Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.01304-09
P932PMC publication ID2876514
P698PubMed publication ID20351175

P2093author name stringHozumi Motohashi
Masayuki Yamamoto
Setsuya Aiba
Mikiko Suzuki
Mariko Takayama
Ryuhei Okuyama
Rie Fujita
P2860cites workA critical role for the transcription factor Scl in platelet production during stress thrombopoiesisQ24292976
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte developmentQ24321429
Megakaryocyte biology and related disordersQ24536140
Isolation of a differentially regulated splicing isoform of human NF-E2Q24564535
Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant miceQ28138589
Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylationQ28142527
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteinsQ28249579
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancyQ28265885
Global regulation of erythroid gene expression by transcription factor GATA-1Q28275891
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant miceQ28277588
Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domainsQ28283769
Regulation of NF-E2 activity in erythroleukemia cell differentiation.Q52189633
A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone marrow transplantation.Q52200606
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficienciesQ74055045
Loss of the transcription factor p45 NF-E2 results in a developmental arrest of megakaryocyte differentiation and the onset of a high bone mass phenotypeQ81552000
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1Q28295662
Transgenic expression of BACH1 transcription factor results in megakaryocytic impairmentQ28299574
Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOGQ28506193
Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 geneQ28509754
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet developmentQ28591602
Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.Q30478947
Consequences of GATA-1 deficiency in megakaryocytes and plateletsQ33328560
Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.Q33330558
Molecular and transcriptional regulation of megakaryocyte differentiationQ33338957
Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopeniaQ33357932
Molecular mechanisms of megakaryopoiesisQ33372252
Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytesQ33503448
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturationQ33608699
p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytesQ33887503
Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteinsQ33929846
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesisQ34034571
Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promotersQ34425014
MafG sumoylation is required for active transcriptional repressionQ34532578
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.Q34604202
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.Q34976601
GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodelingQ35170832
GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesisQ36136740
A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.Q36240033
The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the alpha- and beta-globin gene loci in an erythroid cell lineQ36580348
Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiationQ37099963
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fateQ37291657
Transgene insertion in proximity to the c-myb gene disrupts erythroid-megakaryocytic lineage bifurcationQ39124965
Multiple regions of p45 NF-E2 are required for beta-globin gene expression in erythroid cellsQ39720357
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.Q39864016
Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.Q40146211
Functional characterization of the two alternative promoters of human p45 NF-E2 geneQ40849706
Aphidicolin, an inhibitor of DNA replication, blocks the TPA-induced differentiation of a human megakaryoblastic cell line, MEG-O1Q41652808
Development of myelofibrosis in mice genetically impaired for GATA-1 expression (GATA-1(low) mice).Q44083612
GATA-1 and c-myb crosstalk during red blood cell differentiation through GATA-1 binding sites in the c-myb promoter.Q44389067
Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levelsQ44534261
A WW domain-binding motif within the activation domain of the hematopoietic transcription factor NF-E2 is essential for establishment of a tissue-specific histone modification patternQ44642038
Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitmentQ46617733
Regulation of mouse p45 NF-E2 transcription by an erythroid-specific GATA-dependent intronic alternative promoterQ47873129
NF-E2-mediated enhancement of megakaryocytic differentiation and platelet production in vitro and in vivo.Q50662222
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)2668-2680
P577publication date2010-03-29
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleGenetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis
P478volume30

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cites work (P2860)
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Q27015841Transcription factors in late megakaryopoiesis and related platelet disorders

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