review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0166-6851(99)00197-8 |
P698 | PubMed publication ID | 10743606 |
P50 | author | Hans Westerhoff | Q15989741 |
Barbara Marleen Bakker | Q21551979 | ||
Fred Opperdoes | Q55221768 | ||
P2093 | author name string | P A Michels | |
P2860 | cites work | Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase | Q27617894 |
Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors | Q27618611 | ||
Crystal Structure of Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase from Leishmania mexicana: Implications for Structure-Based Drug Design and a New Position for the Inorganic Phosphate Binding Site | Q27729721 | ||
A Linear Steady-State Treatment of Enzymatic Chains. General Properties, Control and Effector Strength | Q28246120 | ||
Sugar transporters from bacteria, parasites and mammals: structure-activity relationships | Q28292451 | ||
An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei | Q28306793 | ||
Structure-based drug design: progress, results and challenges | Q30419784 | ||
Recent advances in identifying and validating drug targets in trypanosomes and leishmanias. | Q33542293 | ||
Compartmentation of carbohydrate metabolism in trypanosomes | Q34685609 | ||
Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei | Q35615506 | ||
Metabolic control analysis: a survey of its theoretical and experimental development | Q35860764 | ||
Compartmentation of phosphoglycerate kinase in Trypanosoma brucei plays a critical role in parasite energy metabolism | Q36314647 | ||
Structure, function, and biogenesis of glycosomes in kinetoplastida | Q39044849 | ||
Compartmentation of glycolysis in trypanosomes: a potential target for new trypanocidal drugs | Q39249876 | ||
The inhibition of pyruvate transport across the plasma membrane of the bloodstream form of Trypanosoma brucei and its metabolic implications. | Q39591858 | ||
Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis | Q40437048 | ||
The control of flux. | Q40481103 | ||
Inhibition of the glycolytic enzymes in the trypanosome: an approach in the development of new leads in the therapy of parasitic diseases | Q40667215 | ||
Regulation and control of compartmentalized glycolysis in bloodstream form Trypanosoma brucei | Q41040967 | ||
Purification, morphometric analysis, and characterization of the glycosomes (microbodies) of the protozoan hemoflagellate Trypanosoma brucei | Q41457278 | ||
Trypanosoma brucei: Trypanocidal effect of salicylhydroxamic acid plus glycerol in infected rats | Q41680538 | ||
Differential regulation of two distinct families of glucose transporter genes in Trypanosoma brucei | Q43181987 | ||
New approach to screening drugs for activity against African trypanosomes | Q44983593 | ||
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone in Trypanosoma brucei | Q46211203 | ||
Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes. | Q52274817 | ||
Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design. | Q53741874 | ||
What Controls Glycolysis in Bloodstream FormTrypanosoma brucei? | Q57393902 | ||
Subcellular Compartmentation of Glycolytic Intermediates in Trypanosoma brucei | Q58843045 | ||
Specificity of glucose transport in Trypanosoma brucei. Effective inhibition by phloretin and cytochalasin B | Q68036120 | ||
Prospects for antiparasitic drugs. The case of Trypanosoma brucei, the causative agent of African sleeping sickness | Q74263636 | ||
P433 | issue | 1 | |
P304 | page(s) | 1-10 | |
P577 | publication date | 2000-02-01 | |
P1433 | published in | Molecular and Biochemical Parasitology | Q15752756 |
P1476 | title | Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs | |
P478 | volume | 106 |
Q35917161 | A plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis |
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Q36131358 | Aquaporins from pathogenic protozoan parasites: structure, function and potential for chemotherapy |
Q27643297 | Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia |
Q32062530 | Cloning of a pyruvate phosphate dikinase from Trypanosoma cruzi |
Q45007511 | Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei |
Q46041637 | Comparative molecular docking of antitrypanosomal natural products into multiple Trypanosoma brucei drug targets |
Q89662547 | Computational approaches for drug discovery against trypanosomatid-caused diseases |
Q73062299 | Current awareness on comparative and functional genomics |
Q34071727 | Drug uptake via nutrient transporters in Trypanosoma brucei. |
Q41972663 | Enzymatic inhibitory activity and trypanocidal effects of extracts and compounds from Siphoneugena densiflora O. Berg and Vitex polygama Cham |
Q38867546 | Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei |
Q34059533 | Expression of genes encoding F(1)-ATPase results in uncoupling of glycolysis from biomass production in Lactococcus lactis |
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Q92774155 | Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity |
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Q41730167 | Immunological response and protection of mice immunized with plasmid encoding Toxoplasma gondii glycolytic enzyme malate dehydrogenase |
Q47293352 | In Vitro Testing of Potential Entamoeba histolytica Pyruvate Phosphate Dikinase Inhibitors |
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Q27641298 | Leishmania mexicana glycerol-3-phosphate dehydrogenase showed conformational changes upon binding a bi-substrate adduct |
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Q35550669 | Metabolic Engineering: Advances in Modeling and Intervention in Health and Disease |
Q34550535 | Metabolic control analysis in drug discovery and disease |
Q37217309 | Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. |
Q36850342 | Molecular identification and characterization of an essential pyruvate transporter from Trypanosoma brucei |
Q37452948 | Network dynamics |
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Q35080823 | Nutrient transport and pathogenesis in selected parasitic protozoa |
Q34837180 | Promising therapeutic targets for antileishmanial drugs |
Q58842888 | Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution |
Q44103725 | Schemes of flux control in a model of Saccharomyces cerevisiae glycolysis |
Q27656083 | Structure of Insoluble Rat Sperm Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) via Heterotetramer Formation with Escherichia coli GAPDH Reveals Target for Contraceptive Design |
Q27639073 | Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution |
Q26748657 | Synthetic biology and regulatory networks: where metabolic systems biology meets control engineering |
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Q34585708 | Targeting of toxic compounds to the trypanosome's interior |
Q41971759 | The Peculiar Glycolytic Pathway in Hyperthermophylic Archaea: Understanding Its Whims by Experimentation In Silico. |
Q46844882 | The development of an immobilized enzyme reactor containing glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi: the effect of species' specific differences on the immobilization. |
Q43210237 | Trypanocidal activity of the ethyl esters of N-propyl and N-isopropyl oxamates on intracellular amastigotes of Trypanosoma cruzi acute infected mice |
Q35537890 | Why is the Plasmodium falciparum hexose transporter a promising new drug target? |
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