The SOS and RpoS Regulons Contribute to Bacterial Cell Robustness to Genotoxic Stress by Synergistically Regulating DNA Polymerase Pol II.

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The SOS and RpoS Regulons Contribute to Bacterial Cell Robustness to Genotoxic Stress by Synergistically Regulating DNA Polymerase Pol II. is …
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scholarly articleQ13442814

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P356DOI10.1534/GENETICS.116.199471
P932PMC publication ID5500135
P698PubMed publication ID28468910

P50authorTanja DapaQ87157270
P2093author name stringIvan Matic
Marie-Florence Bredeche
Sébastien Fleurier
P2860cites workAfter 30 years of study, the bacterial SOS response still surprises usQ21092806
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Mechanism of DNA polymerase II-mediated frameshift mutagenesisQ28205789
Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymeraseQ28220384
DNA polymerase IIQ28247841
Mitomycin C: small, fast and deadly (but very selective)Q28255522
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase etaQ28286703
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Over 1000 genes are involved in the DNA damage response of Escherichia coliQ28611182
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Separate DNA Pol II- and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS.Q34119281
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS systemQ34144983
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The RpoS-mediated general stress response in Escherichia coliQ34189650
The Brucella abortus xthA-1 gene product participates in base excision repair and resistance to oxidative killing but is not required for wild-type virulence in the mouse modelQ34353973
Interplay between replication and recombination in Escherichia coli: impact of the alternative DNA polymerasesQ34574827
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The bacterial adaptive response gene, barA, encodes a novel conserved histidine kinase regulatory switch for adaptation and modulation of metabolism in Escherichia coliQ35584872
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Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinonesQ35612344
Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutationQ35979376
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Role of sulA and sulB in filamentation by lon mutants of Escherichia coli K-12.Q36308395
β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelityQ36737307
Competitive fitness during feast and famine: how SOS DNA polymerases influence physiology and evolution in Escherichia coliQ36878608
Bacterial DNA repair genes and their eukaryotic homologues: 3. AlkB dioxygenase and Ada methyltransferase in the direct repair of alkylated DNA.Q36933238
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A DNA damage response in Escherichia coli involving the alternative sigma factor, RpoS.Q37062112
Redundant hydrogen peroxide scavengers contribute to Salmonella virulence and oxidative stress resistance.Q37247851
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Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coliQ37403076
Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined positionQ37404894
DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coliQ39495577
Growth phase-regulated expression of bolA and morphology of stationary-phase Escherichia coli cells are controlled by the novel sigma factor sigma S.Q39942389
The SOS regulatory system of Escherichia coliQ40335741
The role of DNA base excision repair in the pathogenesis of Salmonella enterica serovar TyphimuriumQ40562049
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The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activityQ41735615
Thioureas react with superoxide radicals to yield a sulfhydryl compound. Explanation for protective effect against paraquatQ41747382
Alternate pathways of DNA replication in Escherichia coliQ41849408
Selective alleviation of Mitomycin C sensitivity in lexA3 strains of Escherichia coli demands allele specificity of rif-nal mutations: a pivotal role for rpoB87-gyrA87 mutationsQ41852021
Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivityQ41863185
Nucleotide sequence and deletion analysis of the polB gene of Escherichia coliQ42635032
RpoS, the stress response sigma factor, plays a dual role in the regulation of Escherichia coli's error-prone DNA polymerase IV.Q42738196
H2O2 generation during the redox cycle of mitomycin C and dna-bound mitomycin C.Q45367407
XthA (Exonuclease III) regulates loading of RecA onto DNA substrates in log phase Escherichia coli cells.Q50656600
Discovery and Function of a General Core Hormetic Stress Response in E. coli Induced by Sublethal Concentrations of Antibiotics.Q51452645
Effect of pH on DNA alkylation by enzyme-activated mitomycin C and porfiromycin.Q52224535
Mutagenesis and cellular responses to DNA damage.Q54525208
In vitro repair of psoralen-DNA cross-links by RecA, UvrABC, and the 5'-exonuclease of DNA polymerase I.Q54731105
Role of the umuC gene in postreplication repair in UV-irradiated Escherichia coli K-12 uvrB.Q54798484
RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin ActivityQ56761766
Aphidicolin inhibits DNA polymerizing activity but not nucleolytic activity of Escherichia coli DNA polymerase IIQ68118526
Deoxyribonucleic acid plymerase II. of Escherichia coli. I. The purification and characterization of the enzymeQ68637074
Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase IIQ68641863
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesisQ72994394
PCR-mediated gene replacement in Escherichia coliQ73682242
Transcriptional induction of the conserved alternative sigma factor RpoS in Escherichia coli is dependent on BarA, a probable two-component regulatorQ74130059
CROSSLINKING OF DNA BY ENZYMATICALLY OR CHEMICALLY ACTIVATED MITOMYCINS AND PORFIROMYCINS, BIFUNCTIONALLY "ALKYLATING" ANTIBIOTICSQ76959585
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectgenotoxicityQ1009245
P1104number of pages12
P304page(s)1349-1360
P577publication date2017-05-03
P1433published inGeneticsQ3100575
P1476titleThe SOS and RpoS Regulons Contribute to Bacterial Cell Robustness to Genotoxic Stress by Synergistically Regulating DNA Polymerase Pol II.
P478volume206

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cites work (P2860)
Q64115436Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells
Q56875376Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates
Q93185974The SOS system: A complex and tightly regulated response to DNA damage
Q46253040The major contribution of the DNA damage-triggered reactive oxygen species production to cell death: implications for antimicrobial and cancer therapy.
Q98463614Transcriptomic determinants of the response of ST-111 Pseudomonas aeruginosa AG1 to ciprofloxacin identified by a top-down systems biology approach