Reinitiation after translation of two upstream open reading frames (ORF) governs expression of the ORF35-37 Kaposi's sarcoma-associated herpesvirus polycistronic mRNA

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Reinitiation after translation of two upstream open reading frames (ORF) governs expression of the ORF35-37 Kaposi's sarcoma-associated herpesvirus polycistronic mRNA is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00202-14
P932PMC publication ID4093840
P698PubMed publication ID24623444

P2093author name stringJae U Jung
Kevin F Brulois
Britt A Glaunsinger
Lisa M Kronstad
P2860cites workMechanisms governing expression of the v-FLIP gene of Kaposi's sarcoma-associated herpesvirusQ39602182
Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon.Q39868773
Translation of a polycistronic mRNA in the presence of the cauliflower mosaic virus transactivator proteinQ41083475
Close spacing of AUG initiation codons confers dicistronic character on a eukaryotic mRNA.Q41626996
Kaposi's sarcoma-associated herpesvirus vCyclin open reading frame contains an internal ribosome entry siteQ24529088
Upstream open reading frames: molecular switches in (patho)physiologyQ24614000
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)Q24650427
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humansQ24658225
Translation of the first upstream ORF in the hepatitis B virus pregenomic RNA modulates translation at the core and polymerase initiation codonsQ24793781
Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4Q27348186
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomesQ27860600
Ribosome shunting in cauliflower mosaic virus. Identification of an essential and sufficient structural elementQ28260822
Nonlinear ribosome migration on cauliflower mosaic virus 35S RNAQ28269505
Oral ganciclovir for patients with cytomegalovirus retinitis treated with a ganciclovir implant. Roche Ganciclovir Study GroupQ33857954
Recognition of AUG and alternative initiator codons is augmented by G in position +4 but is not generally affected by the nucleotides in positions +5 and +6.Q33886566
Adherence to the first-AUG rule when a second AUG codon follows closely upon the firstQ34489813
An upstream open reading frame modulates ebola virus polymerase translation and virus replicationQ34574867
Dual short upstream open reading frames control translation of a herpesviral polycistronic mRNA.Q34574885
RNA elements directing translation of the duck hepatitis B Virus polymerase via ribosomal shuntingQ35077468
Translational control of C/EBPalpha and C/EBPbeta isoform expression.Q35199785
Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational controlQ36644113
Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteinsQ36779911
Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomesQ36922094
Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trialQ37237122
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapyQ37366303
Reselection of a genomic upstream open reading frame in mouse hepatitis coronavirus 5'-untranslated-region mutantsQ37547381
A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunityQ37648264
Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome cloneQ39323923
Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon inductionQ39573744
Human herpesvirus 8-encoded thymidine kinase and phosphotransferase homologues confer sensitivity to ganciclovirQ39594055
P433issue11
P304page(s)6512-6518
P577publication date2014-03-12
P1433published inJournal of VirologyQ1251128
P1476titleReinitiation after translation of two upstream open reading frames (ORF) governs expression of the ORF35-37 Kaposi's sarcoma-associated herpesvirus polycistronic mRNA
P478volume88

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cites work (P2860)
Q28078469Modulation of the Translational Landscape During Herpesvirus Infection
Q35014918Molecular biology of KSHV lytic reactivation
Q54114449Ribosome Shunting, Polycistronic Translation, and Evasion of Antiviral Defenses in Plant Pararetroviruses and Beyond.
Q41238337Roles of Epstein-Barr virus BGLF3.5 gene and two upstream open reading frames in lytic viral replication in HEK293 cells
Q92257146Transcriptional and post-transcriptional regulation of viral gene expression in the gamma-herpesvirus Kaposi's sarcoma-associated herpesvirus
Q59359160Translational Control in Virus-Infected Cells
Q47576154Viral Short ORFs and Their Possible Functions
Q34112086Viral miRNA targeting of bicistronic and polycistronic transcripts

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