Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

scientific article (publication date: December 2011)

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1002413
P3181OpenCitations bibliographic resource ID840280
P932PMC publication ID3234229
P698PubMed publication ID22174679
P5875ResearchGate publication ID51884637

P50authorDalan BaileyQ28379675
Peter SimmondsQ28379677
Felix YarovinskyQ28379680
Yasmin ChaudhryQ28379681
Ian GoodfellowQ28379682
Andrew MacdonaldQ52644690
Jonathan L. HeeneyQ39066258
P2093author name stringAlicia Benson
Guia Carrara
Nora McFadden
Amita Shortland
P2860cites workA single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulenceQ21089626
Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.Q21090537
MDA-5 recognition of a murine norovirusQ21131596
Leader (L) and L* proteins of Theiler's murine encephalomyelitis virus (TMEV) and their regulation of the virus' biological activitiesQ21245245
Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infectionQ24300481
Viral apoptosis is induced by IRF-3-mediated activation of BaxQ24305369
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
The interferon stimulated gene 54 promotes apoptosisQ24321910
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusQ24336255
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestineQ24604466
Innate cellular response to virus particle entry requires IRF3 but not virus replicationQ24607212
Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulenceQ24644764
Replication of Norovirus in cell culture reveals a tropism for dendritic cells and macrophagesQ24798292
Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivoQ24798502
Detecting overlapping coding sequences in virus genomesQ25255657
STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptorQ27312177
The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal DegradationQ27477650
Coordinated Regulation and Widespread Cellular Expression of Interferon-Stimulated Genes (ISG) ISG-49, ISG-54, and ISG-56 in the Central Nervous System after Infection with Distinct VirusesQ27478040
Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent MechanismsQ27480936
The evolution of genome compression and genomic novelty in RNA virusesQ27481078
Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal calicivirusesQ27486048
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
A novel influenza A virus mitochondrial protein that induces cell death.Q27863709
VISA is an adapter protein required for virus-triggered IFN-beta signalingQ28131814
Expression of the VP2 protein of murine norovirus by a translation termination-reinitiation strategyQ28472315
Molecular basis of cellular localization of poly C binding protein 1 in neuronal cellsQ28506105
Caliciviruses Differ in Their Functional Requirements for eIF4F ComponentsQ56787207
Putting the brakes on the anti-viral response: negative regulators of type I interferon (IFN) productionQ37831564
Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoterQ39548682
Tom70 mediates activation of interferon regulatory factor 3 on mitochondriaQ39680564
Endocytosis of murine norovirus 1 into murine macrophages is dependent on dynamin II and cholesterolQ39717486
Murine norovirus-1 cell entry is mediated through a non-clathrin-, non-caveolae-, dynamin- and cholesterol-dependent pathway.Q39741117
Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon systemQ39756691
Expression of the NS3 protease of cytopathogenic bovine viral diarrhea virus results in the induction of apoptosis but does not block activation of the beta interferon promoterQ39793197
MAVS-mediated apoptosis and its inhibition by viral proteinsQ39858569
Subcellular localizations of the hepatitis C virus alternate reading frame proteinsQ39919651
Recovery of genetically defined murine norovirus in tissue culture by using a fowlpox virus expressing T7 RNA polymeraseQ40109031
N(pro) of classical swine fever virus is an antagonist of double-stranded RNA-mediated apoptosis and IFN-alpha/beta inductionQ40393486
Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54.Q40397234
Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.Q40416432
Ribosomal frameshifting on viral RNAsQ40460979
V and C proteins of measles virus function as virulence factors in vivoQ40903850
Effects of murine norovirus infection on a mouse model of diet-induced obesity and insulin resistanceQ41334543
Close spacing of AUG initiation codons confers dicistronic character on a eukaryotic mRNA.Q41626996
Development of an optimized RNA-based murine norovirus reverse genetics systemQ41685641
Genetic diversity and recombination of murine noroviruses in immunocompromised miceQ42622059
Human enteric caliciviruses have a unique genome structure and are distinct from the Norwalk-like virusesQ42681502
A point mutation in the Sendai virus accessory C proteins attenuates virulence for mice, but not virus growth in cell cultureQ45759046
Detecting overlapping coding sequences with pairwise alignments.Q48525780
Calicivirus translation initiation requires an interaction between VPg and eIF 4 E.Q28507110
Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient SystemsQ29039793
Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine ProteaseQ29614208
The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages.Q30359236
Influenza A virus PB1-F2: a small protein with a big punch.Q30365853
Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumoniaQ30365855
A single amino acid substitution in the murine norovirus capsid protein is sufficient for attenuation in vivo.Q33336969
Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infectionQ33392684
Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responsesQ33573566
Effect of murine norovirus infection on mouse parvovirus infectionQ33670977
Development of a microsphere-based serologic multiplexed fluorescent immunoassay and a reverse transcriptase PCR assay to detect murine norovirus 1 infection in miceQ34072459
STAT1-dependent innate immunity to a Norwalk-like virusQ34182269
Non-AUG-initiated internal translation of the L* protein of Theiler's virus and importance of this protein for viral persistenceQ34348974
Theiler's virus L protein is targeted to the mitochondrial outer membraneQ34742353
Cleavage map and proteolytic processing of the murine norovirus nonstructural polyprotein in infected cellsQ35023930
The genome-linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitmentQ35032545
The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responsesQ35101310
Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulinQ35278976
Access of viral proteins to mitochondria via mitochondria-associated membranesQ35619799
Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivoQ35784950
Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responsesQ35785067
Investigation of the impact of the common animal facility contaminant murine norovirus on experimental murine cytomegalovirus infectionQ35786621
Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA.Q35865077
Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergenceQ36099017
Herpesviruses and the innate immune response.Q36202957
Antibody is critical for the clearance of murine norovirus infectionQ36747984
Apoptosis in murine norovirus-infected RAW264.7 cells is associated with downregulation of survivin.Q37145344
Type I and type II interferons inhibit the translation of murine norovirus proteinsQ37191963
Primary high-dose murine norovirus 1 infection fails to protect from secondary challenge with homologous virusQ37232803
Murine norovirus: an intercurrent variable in a mouse model of bacteria-induced inflammatory bowel disease.Q37261984
Cysteine protease activation and apoptosis in Murine norovirus infectionQ37365778
Effects of acute and chronic murine norovirus infections on immune responses and recovery from Friend retrovirus infectionQ37452443
Hepatitis B virus X gene is implicated in liver carcinogenesisQ37492997
Paramyxovirus disruption of interferon signal transduction: STATus reportQ37582936
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectnorovirusQ1142751
apoptotic processQ14599311
P304page(s)e1002413
P577publication date2011-12-01
P1433published inPLOS PathogensQ283209
P1476titleNorovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4
P478volume7

Reverse relations

cites work (P2860)
Q90367303A semi-nested RT-PCR assay for detection of norovirus in rat fecal samples
Q36506922A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence
Q27016152Advances in norovirus biology
Q59353987Antiviral activity of Schizonepeta tenuifolia Briquet against noroviruses via induction of antiviral interferons
Q90032387Asymmetric evolution in viral overlapping genes is a source of selective protein adaptation
Q52347283Atomic structure of the murine norovirus protruding domain and sCD300lf receptor complex.
Q38833628Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases
Q38657477Bovine noroviruses: A missing component of calf diarrhoea diagnosis
Q64915326Calicivirus RNA-Dependent RNA Polymerases: Evolution, Structure, Protein Dynamics, and Function.
Q64070250Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
Q39038924Characterization of the chemokine response of RAW264.7 cells to infection by murine norovirus.
Q59361138Comparative Transcriptomic Response of Primary and Immortalized Macrophages to Murine Norovirus Infection
Q47548088Construction and Cloning of Reporter-Tagged Replicon cDNA for an In Vitro Replication Study of Murine Norovirus-1 (MNV-1).
Q36377502Critical role of RIG-I and MDA5 in early and late stages of Tulane virus infection
Q36328925Current Status of Norovirus Infections in Children in Sub-Saharan Africa
Q38954444Deep sequencing of norovirus genomes defines evolutionary patterns in an urban tropical setting
Q39365844Development of a reverse-genetics system for murine norovirus 3: long-term persistence occurs in the caecum and colon
Q41875909Development of a strand specific real-time RT-qPCR assay for the detection and quantitation of murine norovirus RNA
Q47549718Distinct Effects of Type I and III Interferons on Enteric Viruses.
Q41144052Effect of TERT on the growth of fibrosarcoma via caspase-3, survivin and PKB
Q90249039Emergence of norovirus strains: A tale of two genes
Q36111292Expression of the NS5 (VPg) Protein of Murine Norovirus Induces a G1/S Phase Arrest.
Q31153401Expression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model
Q33875277Feline calicivirus can tolerate gross changes of its minor capsid protein expression levels induced by changing translation reinitiation frequency or use of a separate VP2-coding mRNA.
Q38354315Functions of the 5' and 3' ends of calicivirus genomes
Q42253921Genetic and evolutionary perspectives on genogroup III, genotype 2 bovine noroviruses
Q61445039Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses
Q38723186HS-AFM and SERS Analysis of Murine Norovirus Infection: Involvement of the Lipid Rafts.
Q34390421High-resolution functional profiling of the norovirus genome
Q34256338High-risk human papillomavirus E5 oncoprotein displays channel-forming activity sensitive to small-molecule inhibitors
Q38705235Histologic Lesions Induced by Murine Norovirus Infection in Laboratory Mice
Q47296262Human Norovirus NS3 has RNA Helicase and Chaperoning Activities
Q38988141ISG15 functions as an interferon-mediated antiviral effector early in the murine norovirus life cycle
Q39288517Identification of RNA-protein interaction networks involved in the norovirus life cycle
Q34987998Identification of immune and viral correlates of norovirus protective immunity through comparative study of intra-cluster norovirus strains
Q63880481Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells
Q98191440In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors
Q38269752Inactivation of norovirus and surrogates by natural phytochemicals and bioactive substances
Q34990499Inactivation of norovirus on dry copper alloy surfaces.
Q36050362Infection with the Persistent Murine Norovirus Strain MNV-S99 Suppresses IFN-Beta Release and Activation of Stat1 In Vitro
Q41516919Influence of genome-scale RNA structure disruption on the replication of murine norovirus--similar replication kinetics in cell culture but attenuation of viral fitness in vivo.
Q64978275Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.
Q33854465Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections
Q47595280Membrane alterations induced by nonstructural proteins of human norovirus.
Q38081826Molecular detection and genotyping of noroviruses
Q36313041Molecular detection of murine noroviruses in laboratory and wild mice
Q92859918Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis
Q38790540Mouse Norovirus infection promotes autophagy induction to facilitate replication but prevents final autophagosome maturation
Q35103915Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection
Q40386666Murine norovirus infection in Brazilian animal facilities
Q49492089Murine norovirus inhibits B cell development in the bone marrow of STAT1-deficient mice
Q41015712Murine norovirus replication induces G0/G1 cell cycle arrest in asynchronously growing cells.
Q95839248New insights into the evolutionary features of viral overlapping genes by discriminant analysis
Q64095412Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
Q38005664Non-canonical translation in RNA viruses
Q40771522Nonstructural protein p39 of feline calicivirus suppresses host innate immune response by preventing IRF-3 activation
Q26864280Norovirus
Q36907013Norovirus (NoV) specific protective immune responses induced by recombinant P dimer vaccine are enhanced by the mucosal adjuvant FlaB.
Q30240631Norovirus Regulation by Host and Microbe
Q40743794Norovirus antagonism of B-cell antigen presentation results in impaired control of acute infection
Q90003022Norovirus encounters in the gut: multifaceted interactions and disease outcomes
Q37252785Norovirus genome circularization and efficient replication are facilitated by binding of PCBP2 and hnRNP A1.
Q28083087Norovirus immunology: Of mice and mechanisms
Q40813688Norovirus in symptomatic and asymptomatic individuals: cytokines and viral shedding.
Q92438540Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation
Q38670949Norovirus mechanisms of immune antagonism
Q36275589Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives
Q33569848Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors
Q38217316Norovirus: targets and tools in antiviral drug discovery
Q40126759Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine-Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2.
Q83229418Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
Q58590580Overlapping genes and the proteins they encode differ significantly in their sequence composition from non-overlapping genes
Q58590010Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells
Q36911792Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses
Q34281184Plasmid-based human norovirus reverse genetics system produces reporter-tagged progeny virus containing infectious genomic RNA.
Q34720811Porcine sapovirus replication is restricted by the type I interferon response in cell culture
Q35901075Proteomic Analysis of the Schistosoma mansoni Miracidium
Q35826359Protruding domain of capsid protein is necessary and sufficient to determine murine norovirus replication and pathogenesis in vivo
Q30155275RETRACTED: Norovirus RNA synthesis is modulated by an interaction between the viral RNA-dependent RNA polymerase and the major capsid protein, VP1.
Q40067139RNA Sequencing of Murine Norovirus-Infected Cells Reveals Transcriptional Alteration of Genes Important to Viral Recognition and Antigen Presentation
Q38761262Recent advances in understanding noroviruses
Q36736602Regulation of Norovirus Virulence by the VP1 Protruding Domain Correlates with B Cell Infection Efficiency.
Q33887631Reinitiation after translation of two upstream open reading frames (ORF) governs expression of the ORF35-37 Kaposi's sarcoma-associated herpesvirus polycistronic mRNA
Q33761808Relationship between genotypes and serotypes of genogroup 1 recoviruses: a model for human norovirus antigenic diversity
Q39320380Reverse genetics mediated recovery of infectious murine norovirus.
Q58716481Robust Innate Immunity of Young Rabbits Mediates Resistance to Rabbit Hemorrhagic Disease Caused by Lagovirus Europaeus GI.1 But Not GI.2
Q35136064Solenopsis invicta virus 3: mapping of structural proteins, ribosomal frameshifting, and similarities to Acyrthosiphon pisum virus and Kelp fly virus
Q47111270Structure and Function of Caliciviral RNA Polymerases.
Q41257306Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions.
Q30239859Structure(s), function(s), and inhibition of the RNA-dependent RNA polymerase of noroviruses
Q64231028Structure-function relationship in the 'termination upstream ribosomal binding site' of the calicivirus rabbit hemorrhagic disease virus
Q24629310Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteins
Q34883353Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases
Q51741116TLR7 agonists display potent antiviral effects against norovirus infection via innate stimulation.
Q63880718Targeting macrophage- and intestinal epithelial cell-specific microRNAs against norovirus restricts replication in vivo.
Q47575056The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus
Q36667813The feline calicivirus leader of the capsid protein is associated with cytopathic effect.
Q41055909The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes
Q38256883The influence of viral RNA secondary structure on interactions with innate host cell defences.
Q38259875The molecular pathology of noroviruses
Q38940840The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis
Q36001052The role of type I interferons in intestinal infection, homeostasis, and inflammation
Q30397112Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes
Q26750947Translational Control during Calicivirus Infection
Q37726158Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures
Q33799843Viral Population Changes during Murine Norovirus Propagation in RAW 264.7 Cells
Q34961642Viral proteins originated de novo by overprinting can be identified by codon usage: application to the "gene nursery" of Deltaretroviruses
Q38766728Viruses in Rodent Colonies: Lessons Learned from Murine Noroviruses
Q55026881miR-155 induction is a marker of murine norovirus infection but does not contribute to control of replication in vivo.

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