| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...619533L |
| P356 | DOI | 10.1371/JOURNAL.PONE.0019533 |
| P932 | PMC publication ID | 3088684 |
| P698 | PubMed publication ID | 21573172 |
| P5875 | ResearchGate publication ID | 51127658 |
| P50 | author | Ching Kung | Q123764436 |
| P2093 | author name string | Zhenwei Su | |
| Stephen Loukin | |||
| P2860 | cites work | Dominant TRPV4 mutations in nonlethal and lethal metatropic dysplasia. | Q51909616 |
| Metatropic dysplasia: clinical and radiographic findings in 11 patients demonstrating long-term natural history. | Q51977340 | ||
| Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family. | Q54422608 | ||
| Spondylo-epiphyseal dysplasia, Maroteaux type (pseudo-Morquio syndrome type 2), and parastremmatic dysplasia are caused by TRPV4 mutations. | Q55052943 | ||
| N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Pa | Q56601579 | ||
| Renal Osteodystrophy | Q58085748 | ||
| Revisiting metatropic dysplasia: Presentation of a series of 19 novel patients and review of the literature | Q63681407 | ||
| Metatropic dysplasia and its variants (analysis of 14 cases) | Q67988125 | ||
| Yeast gain-of-function mutations reveal structure-function relationships conserved among different subfamilies of transient receptor potential channels | Q36288747 | ||
| IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid | Q36527219 | ||
| A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating | Q36710217 | ||
| Modulation of transient receptor potential Vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C. | Q37116100 | ||
| Bone remodeling during fracture repair: The cellular picture. | Q37240518 | ||
| A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia | Q37310734 | ||
| Molecular mechanisms of TRPV4-mediated neural signaling | Q37348481 | ||
| Activation of the TRPV4 ion channel is enhanced by phosphorylation. | Q37459860 | ||
| Brachyolmia: radiographic and genetic evidence of heterogeneity | Q38676414 | ||
| Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study | Q39861832 | ||
| Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli. | Q39912354 | ||
| Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation | Q40084522 | ||
| Temperature-modulated diversity of TRPV4 channel gating: activation by physical stresses and phorbol ester derivatives through protein kinase C-dependent and -independent pathways | Q40648956 | ||
| Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells | Q40700786 | ||
| Transient receptor potential vanilloid 4 deficiency suppresses unloading-induced bone loss. | Q42817046 | ||
| Modulation of TRPV4 gating by intra- and extracellular Ca2+. | Q44452825 | ||
| Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels | Q44524443 | ||
| TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts | Q45749407 | ||
| Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease | Q46083919 | ||
| Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila. | Q47070695 | ||
| OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity | Q24290380 | ||
| Ca2+-dependent Potentiation of the Nonselective Cation Channel TRPV4 Is Mediated by a C-terminal Calmodulin Binding Site | Q24300879 | ||
| Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C | Q24595706 | ||
| Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor | Q24647926 | ||
| Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C | Q27658802 | ||
| TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling | Q30438420 | ||
| TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells | Q30483343 | ||
| Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4. | Q30547553 | ||
| Bisandrographolide from Andrographis paniculata activates TRPV4 channels. | Q30821637 | ||
| Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation | Q33386567 | ||
| Global comparative transcriptome analysis of cartilage formation in vivo | Q33416200 | ||
| Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4 | Q33582066 | ||
| Forward genetic analysis reveals multiple gating mechanisms of TRPV4 | Q33924287 | ||
| Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force | Q34094517 | ||
| Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives | Q34112760 | ||
| TRPV4-pathy, a novel channelopathy affecting diverse systems | Q34117611 | ||
| Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. | Q34522629 | ||
| Kozlowski type spondylometaphyseal dysplasia: a case report with literature review | Q34568102 | ||
| Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia | Q34790129 | ||
| IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site. | Q34841332 | ||
| Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia | Q34949511 | ||
| Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4. | Q35123129 | ||
| Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint-waddler mice. | Q36157007 | ||
| A helix-breaking mutation in TRPML3 leads to constitutive activity underlying deafness in the varitint-waddler mouse | Q36288732 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e19533 | |
| P577 | publication date | 2011-05-05 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutations | |
| P478 | volume | 6 |
| Q36760317 | A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function. |
| Q35910190 | A channelopathy mechanism revealed by direct calmodulin activation of TrpV4. |
| Q37369327 | A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open |
| Q52162409 | A mutation in TRPV4 results in altered chondrocyte calcium signaling in severe metatropic dysplasia |
| Q92698690 | Combined Phenotypes of Spondylometaphyseal Dysplasia-Kozlowski Type and Charcot-Marie-Tooth Disease Type 2C Secondary to a TRPV4 Pathogenic Variant |
| Q28658571 | Feeling the hidden mechanical forces in lipid bilayer is an original sense |
| Q57234082 | Fetal akinesia in metatropic dysplasia: The combined phenotype of chondrodysplasia and neuropathy? |
| Q33613251 | Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations |
| Q30276535 | Gain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral head |
| Q36514432 | Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation |
| Q35212642 | L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel |
| Q39464645 | Mutations in TRPV4 cause an inherited arthropathy of hands and feet. |
| Q90422145 | Mutations in calmodulin-binding domains of TRPV4/6 channels confer invasive properties to colon adenocarcinoma cells |
| Q36738586 | Novel mutations highlight the key role of the ankyrin repeat domain in TRPV4-mediated neuropathy |
| Q33788974 | Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1 |
| Q50102613 | Sensing and regulation of cell volume - we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role? |
| Q27681184 | Structural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 Channel |
| Q27680759 | Structure of the TRPV1 ion channel determined by electron cryo-microscopy |
| Q34537097 | Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia |
| Q34287791 | TRPV4-associated skeletal dysplasias |
| Q38830274 | The TRPCs, Orais and STIMs in ER/PM Junctions |
| Q38216887 | The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements |
| Q94564833 | Transient receptor potential vanilloid 1 and 4 double knockout leads to increased bone mass in mice |
| Q49806546 | Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A-mediated phosphorylation |
| Q36584629 | Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias |
| Q47228512 | When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor. |
| Q39630828 | Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4. |
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